International Journal of Orthopaedics Research最新文献

{"title":"Janus Kinase Inhibitors: Hope for Biotherapy in Sub-Saharan Africa?","authors":"","doi":"10.33140/ijor.04.03.07","DOIUrl":"https://doi.org/10.33140/ijor.04.03.07","url":null,"abstract":"Introduction: Tofacitinib is an oral Janus Kinase (JAK) inhibitor used in the treatment of rheumatoid arthritis (RA) and in many other conditions [1-3]. After promising results in clinical and preclinical trials, Tofacitinib was extensively evaluated in pivotal trials in 2012 and its efficacy on demonstrated structural damage [4]. Thus, Tofacitinib has been approved for the treatment of patients with RA who have an inadequate response to methotrexate [5]. Biologics are used routinely in many countries but remain difficult to access in sub-Saharan Africa [6]. The cost of biotherapies, their side effects, in particular infectious ones, and their presentation in injectable form constitute a brake on the use of these new treatments. The advent of a new therapy administered by bone would represent an excellent alternative for Africa. We thus report the case of a patient who failed conventional treatments and who has benefited from Tofacitinib (Xeljanz 5mg®).","PeriodicalId":192630,"journal":{"name":"International Journal of Orthopaedics Research","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127363676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimal Brain Dysfunction. Children and adults. Clinical and Psychological Symptoms. Examples of pathology. Rules of Therapy","authors":"","doi":"10.33140/ijor.04.03.08","DOIUrl":"https://doi.org/10.33140/ijor.04.03.08","url":null,"abstract":"In the paper there are presented observations from the years 1995-2021. Material content of 1355 children and youths in the ages between 2 and 18 years and adults 20-70 years old. In the article they are present the clinical symptoms of Minimal Brain Dysfunction [MBD]. Clinically there are: valgus deformity of the feet, hyperextension of the knees, anterior tilt of the pelvis, hyperlordosis of the lumbar spine. These symptoms are as result of spasticity or sub-spasticity of the muscles. At the same time, we observe in this group of patients “laxity of joints” and this is a result of the changes in the properties of collagen. In the MBD group of patients-there are very often also psychological disorders-similarly like in cases of Attention Deficit & Hyperactivity Disorder (ADHD). Children with MBD often present inclination to hyperactivity-frequent jumping-and it is the main cause of Perthes disease. There are also psychological changes in behavior in adults-and this is described in “Discussion”. It is also given information about physiotherapy of the diseases and disorders in movement system.","PeriodicalId":192630,"journal":{"name":"International Journal of Orthopaedics Research","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132643893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Less Invasive Treatment of 265 Intraarticular Calcaneal Fractures with An Interlocking Nail (C-nail)","authors":"","doi":"10.33140/ijor.04.03.02","DOIUrl":"https://doi.org/10.33140/ijor.04.03.02","url":null,"abstract":"Objectives: Less invasive restoration of joint congruity and calcaneal shape in displaced intra-articular calcaneal fractures via a sinus tarsi approach followed by minimally invasive internal fixation with an interlocking nail (C-nail) results in a low rate of soft-tissue complications and good outcomes. Design: Prospective case-control study. Setting: Regional Hospital Trauma Department Patients: A total of 265 calcaneal fractures were treated by using the C-nail between 2011 and 2018 at the Department of Traumatology at the Regional Hospital Pardubice. Intervention: The reduced joint surface was fixed with one or two screws with short thread. All other fragments were fixed after reduction with the C-Nail introduced through the tuberosity. The fragments were fixed with 7 interlocking screws passing through the nail. Main Outcome Measures: Patients were assessed for complications, restoration of Böhler angle, posterior facet reduction with postoperative computed tomography, and weight-bearing radiographs after 6 and 12 months. Results: Wound edge necrosis was seen in three cases (1.1%) and soft tissue infection was observed in one case (0.4%). Böhler’s angle was improved from 5.9° preoperatively to 32.1° postoperatively, measuring 27.6° after 12 months. Conclusions: Two hundred forty-nine patients (222 males and 27 females; mean age 47.3 years) with 265 calcaneal fractures were treated between 2011 and 2018 less-invasively. The sinus tarsi-approach with use of the C-nail shows low risk of infection due to high stability of the fixed fracture.","PeriodicalId":192630,"journal":{"name":"International Journal of Orthopaedics Research","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134499411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidental Dural Tear in Lumbar Spine Surgery: A Prospective Study","authors":"","doi":"10.33140/ijor.04.03.01","DOIUrl":"https://doi.org/10.33140/ijor.04.03.01","url":null,"abstract":"Introduction: Incidental dual tear is a complication of spinal surgery characterized by an accidental nick of the spinal dural sheath during operative procedures. The worldwide incidence of dural tear according to previous literature varies widely (1- 17%) and in general depends on the type and complexity of the procedure. The present was carried to evaluate the incidence of dural tear in lumbar spine surgery, and to study clinical outcomes in terms of VAS score ODI score and length of hospital stay. Methods: This was a prospective, observational and case control study conducted on 40 patients who underwent elective Lumbosacral spine surgery. The incidence of dural tear was evaluated and the patients were divided into with dural tear and without dural tear. The clinical outcome such as visual analogue scale (VAS) score, Oswestry Disability Index (ODI) score and length of hospital stay were evaluated. Results: The incidence of Dural tear in our study population was found to be 7.5%. The ODI score was significantly higher in dural tear as compared to without dual tear at various postoperative periods. Further, there was no significant difference in the VAS scores with and without dural tear patients. The length of hospital stay was significantly higher in patients with dural tear as compared to without dural tear (11.63±6.19 vs 3.06±1.02 days; p=0.004). Conclusion: Incidental Dural tears if detected and managed accordingly, adverse clinical and postoperative outcomes can be reduced effectively and also increases the quality of life in patients.","PeriodicalId":192630,"journal":{"name":"International Journal of Orthopaedics Research","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124731094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harmful Effects of COVID-19 on Mental Health and Its Social Repercussions","authors":"","doi":"10.33140/ijor.04.002","DOIUrl":"https://doi.org/10.33140/ijor.04.002","url":null,"abstract":"Introduction: The COVID-19 pandemic constitutes a global emergency, with a high impact on public health, including mental health. This situation currently represents a challenge for health professionals in all fields. In the absence of a definitive cure, the most effective measures to reduce the number of infected cases is those that involve social isolation and specifically the establishment of quarantines. Objective: To determine the psychological disorders most frequently presented during the Covid-19 pandemic. Methods: A bibliographic and documentary review was carried out on the subject in authorized digital data sources and websites of recognized scientific prestige on psychological and social aspects, linked to the epidemics that occurred historically and in particular to the Covid-19 pandemic. The consultations were made in Scopus, EBSCO Health, PubMed (search engine), SciELO and PsycINFO, with an emphasis on original articles and systematic reviews. For the search, the following keywords were used in English and Spanish: quarantine, social isolation, psychological impact, psychological and social reaction. Conclusions: Prolonged confinement and social distancing during the COVID-19 pandemic has been responsible for the deterioration of mental health in some individuals, due to the post-traumatic stress that these conditions generate, manifesting itself more frequently by anxiety, depression, insomnia and panic. which has led to harmful behaviors and inappropriate social behaviors, explained in a general way by anxiety and panic of deficiencies, mainly food.","PeriodicalId":192630,"journal":{"name":"International Journal of Orthopaedics Research","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128407070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Retrospective Audit of Indwelling Urinary Catheter Practices in Primary Hip Fracture Patients at Fiona Stanley Hospital","authors":"","doi":"10.33140/ijor.04.02.04","DOIUrl":"https://doi.org/10.33140/ijor.04.02.04","url":null,"abstract":"The pre-operative utilisation of indwelling urinary catheters (IDCs) has become standard orthopaedic practice in patients with hip fractures with the aim to minimise the incidence of post-operative bladder dysfunction which occurs due to administration of analgesia and anaesthesia [1]. Despite the practical benefits of IDC insertion, there are well-documented associated risks which include hospital-acquired urinary tract infection (UTI), which is positively correlated with its duration in situ-estimated to be around 5-10% each catheter day after the first 48 hours of catheterisation [2]. Hospital-acquired UTIs have significant patient and healthcare costs, resulting in prolonged hospital stay, bacteraemia, prosthetic joint infections, and death [1].","PeriodicalId":192630,"journal":{"name":"International Journal of Orthopaedics Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131306839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seasonal Trends in Operative Pediatric Supracondylar Humerus and Femoral Shaft Fractures at a Pediatric Level 1 Trauma Center","authors":"","doi":"10.33140/ijor.04.02.05","DOIUrl":"https://doi.org/10.33140/ijor.04.02.05","url":null,"abstract":"Background: Supracondylar humerus (SCHF) and femoral shaft (FSF) fractures are two common injuries at pediatric trauma centers. While anecdotally we see an increase in injuries with warmer weather, the purpose of this study was to objectively describe the seasonal variation in these operative fractures, and their relative burden on hospital census. Methods: We performed an IRB-approved, retrospective review of 1626 SCHF and 601 FSF treated operatively from 2013-2018 at a single level 1 pediatric trauma center. Dates of injury were categorized with hospital census information, and temperature and precipitation data were obtained through the National Weather Service. Results: For every 10º F increase in temperature, there was a 5% increased likelihood of FSF (p=0.048) and a 26% increased likelihood of SCHF (p=<0.0001). FSF were less likely to occur on weekdays than weekends (OR 0.59, p<0.0001) and less likely to occur on days with precipitation (OR 0.41, p= 0.03). SCHF demonstrated no significant weekly or precipitation-related trends. SCHF represent a significantly larger burden on orthopedic volume during summer months. The ratio of operative FSF relative to the total orthopedic volume per month did not correlate with season. Conclusions: As often anecdotally reported, SCHF volumes mirror temperature variations annually. FSF appear to have more complex trends, with increased incidence on weekends regardless of season. Geographic variation in weather contributes strongly to pediatric trauma volume, and the ability to forecast a hospital system’s operative fracture volume allows for responsible resource allocation during key periods. Level of Evidence: Retrospective case series, Level IV","PeriodicalId":192630,"journal":{"name":"International Journal of Orthopaedics Research","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131867539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of UCBL and Medial Longitudinal Arch Support in Balance and Functional Performance in Bilateral Flexible Flat Feet in Patients Aged Between 16 And 20 Years","authors":"","doi":"10.33140/ijor.04.02.03","DOIUrl":"https://doi.org/10.33140/ijor.04.02.03","url":null,"abstract":"Purpose: Moulded foot orthoses have been shown to be successful in treating such injuries and reducing the symptoms by realigning the foot anatomy, controlling excessive pronation and reducing internal tibial rotation. Numerous prophylactics or therapeutic devices, such as motion control shoe, orthoses, orthotic devices, inserts and others, have emerged to limit the pronation range during running. In evaluating the effect of these devices to control pronation during running, orthopaedics and biomechanics researchers often investigate the rearfoot kinematics, or to be specific, the calcaneal motion in respect to the talus bone. Previous researches showed that the effects are still unclear however some orthotic inserts are useful in relieving heel and plantar fasciitis pain. The purpose of this study is to identify among UCBL and Medial Arch Support which is a better prescription option for Pes planus. Materials and Method: An incidental simple randomised sample of 30 participants (30 Bilateral Flexible Flat Feet) were recruited for the study with age range from 16 to 20 years. There were 21 male and 9 female patients in the study. There was no drop out during the study. Participants were allocated to two groups by random allocation based on the fitment of UCBL and arch support (UCBL prescribed for Group A and Medial arch support prescribed for Group B). Pre and post interventional tests- balance and functional parameters was taken before the fitment of orthosis and after four-week of usage of the prescribed orthotic treatment and the said pre and post interventional data was analysed for statistical significance. Result: One-way ANOVA test shows a significant difference between groups at p<0.000. Posttest between the parameters (Berg balance and TUG) shows that UCBL has a high statistical significance than medial arch support in improving balance and functional parameters at p<0.000 at t value -6.942. Conclusion: A comparison of balance and functional parameter results in the tested orthoses indicated that the UCBL orthosis significantly increased the stability of people with flexible flatfoot, and it has improved balance and functional parameters in total among those with flatfeet. It seems that creating mobility in the midfoot area of the foot orthosis may cause a balance disturbance in patients with flatfoot. It is recommended that other balance parameters such as sway of the center of pressure and the long-term effects of orthoses may also be investigated.","PeriodicalId":192630,"journal":{"name":"International Journal of Orthopaedics Research","volume":"5 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113956875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"After Total Knee Arthroplasty Different Knee Position Bring Distinct Effects-a Prospective Study of One Hundred Patients","authors":"ke zheng, Wenxia Liu, Jiewen Zhang","doi":"10.21203/rs.3.rs-588449/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-588449/v1","url":null,"abstract":"\u0000 Background Following total knee arthroplasty (TKA) blood loss is a major factor influencing functional recovery and quality of life in patients. The aim of this study was to determine the effect of postoperative leg position on blood loss and functional recovery after TKA.Methods One hundred consecutive patients were enrolled in this prospective randomized study, which with degenerative osteoarthritis of the knee. An equal number of patients were randomly allocated to either flexion or extension groups. In the flexion group, the affected leg was elevated 45° at the hip and with 45° of flexion at the knee, while patients in the extension group had the knee extended fully. Primary outcomes were calculated total blood loss (CBL), hidden blood loss(HBL), intraoperative blood loss(IBL),haemoglobin(HB) level and haematocrit(HCT).Results CBL, HBL, postoperative levels of HB and HCT, drop level of HB and HCT between the two groups after 72 hours were significantly different, with patients in the flexion group experiencing lower blood loss than those in the extension group (P < 0.05).However, there no difference between groups in the postoperative levels of HB and HCT, drop level of HB and HCT at 24 hours. Even though after 1 week range of motion (ROM) was statistical difference in groups, but after 6-week rehabilitation, patients from both groups attained a similar ROM in the knee. Conclusions The results of this study definite that after TKA execute the protocol，maintaining a position with the hip 45°flexion and the knee flexed at 45° prolong 48 hours, is an effective method for reducing blood loss and increasing functional ROM.","PeriodicalId":192630,"journal":{"name":"International Journal of Orthopaedics Research","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132642871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Management of Trigger Finger: A 5-Year Retrospective Review","authors":"","doi":"10.33140/ijor.04.02.02","DOIUrl":"https://doi.org/10.33140/ijor.04.02.02","url":null,"abstract":"Stenosing tenosynovitis, generally known as Trigger Finger (TF), is a common hand disorder characterized by pain and locking of the affected digit, which is often found on the dominant hand [1- 3]. This locking occurs when swelling or thickening of the flexor tendon restricts its ability to glide through the A1 pulley during flexion or extension [4, 5]. The general population has a two percent lifetime risk of developing trigger finger, with an average age of onset of 50 years [6, 7]. Women are affected up to six times more than men and diabetics have an increased risk of 10% [8, 9]. Although all digits are susceptible, evidence has shown the ring finger and thumb to be the most affected [10].","PeriodicalId":192630,"journal":{"name":"International Journal of Orthopaedics Research","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114152637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}