Noise & HealthPub Date : 2024-10-01Epub Date: 2024-12-30DOI: 10.4103/nah.nah_71_24
Lan Zhang, Hui Liao, Zongnan Li, Jianhui Yuan
{"title":"Individual and combined effects of noise exposure and diabetes mellitus on hearing.","authors":"Lan Zhang, Hui Liao, Zongnan Li, Jianhui Yuan","doi":"10.4103/nah.nah_71_24","DOIUrl":"10.4103/nah.nah_71_24","url":null,"abstract":"<p><p>Hearing loss (HL) is a prevalent health concern with a significant impact on society and the economy. Several factors contribute to the development of hearing impairment, with noise overexposure being the primary culprit. Diabetes mellitus (DM) is also a factor in hearing impairment, and studies have shown a positive correlation between DM and HL; however, the exact causal relationship and pathogenesis remain contentious. Given the ubiquity of noise exposure and the high incidence of DM, individuals may develop diabetes while being chronically exposed to noise. It is particularly important to explore the independent and combined effects of noise and DM on hearing, which can help healthcare professionals understand the potential risks posed by these factors and inspire prevention strategies and potential interventions for hearing impairment. This review summarizes the current research advancements in noise-induced HL and diabetes-related HL and discusses their characteristics and potential mechanisms. Furthermore, this review focuses on the combined effects of noise exposure and DM on hearing, setting the stage for further research and development of intervention strategies to address HL.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 123","pages":"449-460"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142951953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-10-01Epub Date: 2024-12-30DOI: 10.4103/nah.nah_98_24
Haroldas Razvadauskas, Jurgita Razvadauskienė, Martynas Aliulis, Rūta Aliulytė, Albinas Naudžiūnas, Renata Paukštaitienė, Saulius Sadauskas
{"title":"Influence of Gaussian White Noise on Medical Students' Capacity to Accurately Identify Pulmonary Sounds.","authors":"Haroldas Razvadauskas, Jurgita Razvadauskienė, Martynas Aliulis, Rūta Aliulytė, Albinas Naudžiūnas, Renata Paukštaitienė, Saulius Sadauskas","doi":"10.4103/nah.nah_98_24","DOIUrl":"10.4103/nah.nah_98_24","url":null,"abstract":"<p><strong>Background: </strong>The effect of background noise on auscultation accuracy for different lung sound classes under standardised conditions, especially at lower to medium levels, remains largely unexplored. This article aims to evaluate the impact of three levels of Gaussian white noise (GWN) on the ability to identify three classes of lung sounds.</p><p><strong>Methods and materials: </strong>A pre-post pilot study assessing the impact of GWN on a group of students' ability to identify lung sounds was conducted. The three intensities were applied to the three classes of lung sounds: no GWN, signal-to-noise ratio (SNR), SNR-40 (medium level) and SNR-20 (high). This resulted with three exams, each containing nine questions. Fifty-two participants underwent a 4-day training programme and were tested on their identification of lung sound classes under the three levels of GWN, but seven subjects were excluded for not completing all three assessments. Statistical analysis was performed on 45 subjects, using non-parametric tests to analyse the data. A P-value of 0.05 was considered statistically significant.</p><p><strong>Results: </strong>The GWN did not impact the overall lung sound identification capacity of medical students, with consistent scores of 66.7% across the three noise levels for all three lung sound classes combined. However, when considering sound classes separately, GWN affected the identification of normal (NAS) and discontinuous (DAS), but not continuous (CAS) types. Exam scores for NAS varied significantly across the three noise levels, with respective scores of 66.7%, 100% and 66.7%. Scores for DAS also varied, revealing 66.7%, 33.3% and 66.7%.</p><p><strong>Conclusion: </strong>This study introduces a standardised simulation-based approach to investigate the effect of GWN on the accuracy of auscultation amongst medical students. Findings indicate that whilst CAS sounds are robust to background noise, the identification of NAS and DAS sounds can be compromised. The medium noise levels (SNR-40) of noise pollution had the greatest effect on the DAS lung sounds.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 123","pages":"474-482"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142952298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-10-01Epub Date: 2024-12-30DOI: 10.4103/nah.nah_106_24
Shujian Zhang, Li Shen, Qian Wang, Shuhong Yu
{"title":"Correlation between Occupational Noise Exposure and Renal Dysfunction in Male Workers.","authors":"Shujian Zhang, Li Shen, Qian Wang, Shuhong Yu","doi":"10.4103/nah.nah_106_24","DOIUrl":"10.4103/nah.nah_106_24","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to explore the relationship between occupational noise exposure and renal dysfunction in male workers.</p><p><strong>Methods: </strong>A total of 160 male workers (the number of people who met the inclusion criteria) who underwent health examinations in Qingdao Municipal Hospital from January 2023 to December 2023 were grouped into a noise group (80 cases) and a control group (80 cases) based on whether they engaged in noise work. We compared the differences in creatinine (CREA), cystatin C (CysC) and blood urea nitrogen (BUN) levels between the two groups. We also compared the differences in the above renal function indicators among workers with different working years in the noise group, as well as observed the relationship between renal dysfunction and noise exposure.</p><p><strong>Results: </strong>The levels of BUN, CREA and CysC in the noise group were significantly higher than those in the control group (P < 0.05). The overall abnormal rate of renal function in the noise group (42.50%) was significantly higher than that in the control group (11.25%, P < 0.05). The levels of BUN, CREA and CysC all significantly increased with the increase in working years (P < 0.05). The noise exposure intensity and cumulative noise exposure (CNE) of the group with renal dysfunction were higher than those of the group with normal renal function (P < 0.05). The area under the curve was 0.811 (95% confidence interval: 0.714-0.908), the optimal cut-off value of CNE was 96.53 dB (A) · year, the sensitivity was 89.29%, the specificity was 83.32% and the Youden index was 72.61%.</p><p><strong>Conclusion: </strong>There may be a correlation between long-term noise exposure and renal function. The intensity of noise exposure and CNE may have a certain correlation with renal function damage in occupational noise-exposed workers.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 123","pages":"559-565"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142952313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Noise in Paediatric Dentistry and Change in Perception of Operators with Use of Ear Protection Devices.","authors":"Anshula Neeraj Deshpande, Simron Baishya, Sonali Saha, Vasudha Sodani, Riddhika Shah, Aishwarya Antala","doi":"10.4103/nah.nah_72_24","DOIUrl":"10.4103/nah.nah_72_24","url":null,"abstract":"<p><strong>Background: </strong>Noise sources in paediatric dental offices include machinery and children's cries and screams. Although the presence of occupational noise-induced hearing loss (ONIHL) among dental operators is established, preventive measures such as ear protection devices (EPDs) are not frequently employed as prophylactic intervention. The primary aim of this study was to quantitatively assess the noise levels in paediatric dental clinics and to qualitatively evaluate the operators' perception of noise with and without the use of EPDs.</p><p><strong>Methods: </strong>A crossover study was conducted with 93 operators; half of whom first worked without EPD, and the other half worked with EPD. Sound produced near each operator was recorded in decibels (dBs) for five working days, and the maximum sound in decibel for each day was noted and averaged. The results were then compared with the Occupational Safety and Health Administration (OSHA) and National Institute for Occupational Safety and Health (NIOSH) exposure limits. A questionnaire was handed out before the commencement of the study, and another at the end of the study.</p><p><strong>Results: </strong>The average noise level was 86.68 dB without EPD and 86.83 dB with EPD. About 65.59% dentists considered the level of noise at their workplace to be medium level, and 98.92% did not wear EPD. Most common findings, such as irritability at the end of the day (77.42%), were relieved after use of EPD in 92.47% dentists.</p><p><strong>Conclusion: </strong>The noise in the paediatric department is above the NOISH-recommended exposure limit, which is harmful to the auditory system. In general, dentists are knowledgeable about the noise in the operatory, although their knowledge about EPDs is not high.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 123","pages":"501-506"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142951532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-10-01Epub Date: 2024-12-30DOI: 10.4103/nah.nah_86_24
Yuqing Wang, Lin Wang, Shuhua Lin, Zhaode Zhang, Xiaoqing Li, Lingli Lin
{"title":"Relationship between Age-Related Hearing Loss and Age-Related Macular Degeneration.","authors":"Yuqing Wang, Lin Wang, Shuhua Lin, Zhaode Zhang, Xiaoqing Li, Lingli Lin","doi":"10.4103/nah.nah_86_24","DOIUrl":"10.4103/nah.nah_86_24","url":null,"abstract":"<p><strong>Background: </strong>With the aging of the population, the deterioration of visual and auditory functions amongst the elderly has attracted much attention. Age-related hearing loss (ARHL) and age-related macular degeneration (AMD) are common eye and ear diseases that seriously affect the quality of life of elderly population.</p><p><strong>Methods: </strong>This study utilised a whole cohort sampling method, with a total of 713 participants aged 50 years and older in the community from June 2022 to October 2023, resulting in the inclusion of 620 participants. Demographic information was collected from these participants, and eye and hearing examinations were conducted at Ningde Municipal Hospital affiliated of Fujian Medical University. Spearman's correlation analysis was utilised to investigate the association between ARHL and AMD in patients. Multivariate logistic regression analysis was employed to identify the factors influencing ARHL to provide insights for preventing and treating ARHL and AMD in older individuals.</p><p><strong>Results: </strong>Correlation analysis indicated a significantly positive relationship between ARHL and AMD (P < 0.001). The results showed that age, medical history, AMD and chronic noise exposure were risk factors for ARHL.</p><p><strong>Conclusions: </strong>There were 196 cases of AMD in ARHL patients (82.35%). Spearman's correlation analysis revealed that ARHL was associated with AMD; logistic regression analysis revealed that age, medical history, macular degeneration and history of prolonged noise exposure were risk factors for ARHL. Among them, age, medical history (hypertension, hyperlipidaemia and diabetes mellitus), noise and AMD influence the development of ARHL in the elderly population. Therefore, attention should be paid to controlling risk factors in this population to prevent or reduce the development of ARHL.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 123","pages":"483-488"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142952265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-10-01Epub Date: 2024-12-30DOI: 10.4103/nah.nah_10_24
Sofia Temam, Nathalie Billaudeau, Sofiane Kab, Marie Zins, Marie-Noël Vercambre
{"title":"Occupational noise, work-related stress, and teachers' health in the French CONSTANCES study.","authors":"Sofia Temam, Nathalie Billaudeau, Sofiane Kab, Marie Zins, Marie-Noël Vercambre","doi":"10.4103/nah.nah_10_24","DOIUrl":"10.4103/nah.nah_10_24","url":null,"abstract":"<p><strong>Objective: </strong>Besides psychosocial stressors, teachers are exposed to disturbing noise at work, such as students' irrelevant speech. Few studies have focused on this issue and its health consequences. We explored occupational noise exposure among teachers within the French workforce and analyzed how noise and work-related stress are related to their health.</p><p><strong>Materials and methods: </strong>The prevalence of perceived noise exposure, evaluated through the question \"Do you work in an environment where you sometimes have to raise your voice to talk to people 2 to 3 m away?\" was compared between teachers (n = 13,843) and various occupational groups (n = 34,338) using inclusion data (2012-2020) from the ongoing French population-based CONSTANCES cohort (>217,000 participants). Additionally, the relationships between perceived noise and two health dimensions, perceived health (poor vs. good) and depressive symptoms (Centre for Epidemiologic Studies-Depression Scale, high vs. low/moderate), among teachers were alternately investigated using logistic regressions. Moreover, how perceived noise may interact with work-related stress (effort-reward imbalance/strained relationships) was explored.</p><p><strong>Results: </strong>Thirty-two percent of teachers reported working in a noisy environment, compared with 14% of noneducation employees (P < 0.001). Primary school teachers were the most likely to report noise exposure (43%). Independent of stress, teachers exposed to noise had poorer perceived health and higher odds of depressive symptoms than nonexposed teachers, with odds ratios (95% confidence interval) of 1.21 (1.07; 1.37) and 1.14 (1.01; 1.28), respectively. Evidence of an interaction between perceived noise and strained relationships was observed on perceived health (P = 0.05).</p><p><strong>Conclusion: </strong>French teachers commonly reported disturbing noise at work, and those exposed showed poorer health indicators, particularly when facing strained relationships. The findings call for further studies on noise in schools, especially longitudinal studies, to ascertain its long-term effect on teachers' health and its potential interaction with the psychosocial environment.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 123","pages":"523-534"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142952339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-10-01Epub Date: 2024-12-30DOI: 10.4103/nah.nah_162_24
Goran Belojević
{"title":"Sound and Alzheimer's Disease-From Harmful Noise to Beneficial Soundscape Augmentation and Music Therapy.","authors":"Goran Belojević","doi":"10.4103/nah.nah_162_24","DOIUrl":"10.4103/nah.nah_162_24","url":null,"abstract":"<p><p>Exposure to sound energy may be a risk factor or a therapeutic intervention for Alzheimer's disease (AD). On one hand, noise has a harmful effect on people with AD by contributing to hearing loss, sleep disturbance, oxidative stress, inflammation, and excitotoxicity. But on the other hand, clinical trials and nursing home interventions with soundscape augmentation involving natural sounds have shown promising results in alleviating psychophysiological symptoms in people with AD. Music therapy, an emerging non-pharmacological treatment, can improve cognition, reduce anxiety and depression, and enhance self-awareness in patients with AD. To ensure that music does not become noise in clinical trials, only favorite music at levels safe for hearing should be used. From a public health standpoint, noise countermeasures, soundscape augmentation with natural sounds, and active or passive engagement with music may be regarded as potentially powerful strategies for the prevention of AD.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 123","pages":"445-448"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142952347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-10-01Epub Date: 2024-12-30DOI: 10.4103/nah.nah_111_24
Gang Yin, Na Li, Dan Xu, Zhen Meng, Shuyun Zheng, Ying Chen
{"title":"Effects of White Noise Intervention on Sleep Quality and Immunological Indicators of Patients with Breast Cancer Undergoing Neoadjuvant Chemotherapy.","authors":"Gang Yin, Na Li, Dan Xu, Zhen Meng, Shuyun Zheng, Ying Chen","doi":"10.4103/nah.nah_111_24","DOIUrl":"10.4103/nah.nah_111_24","url":null,"abstract":"<p><strong>Objective: </strong>Evaluate the effect of white noise intervention on sleep quality and immunological indicators of patients with breast cancer undergoing neoadjuvant chemotherapy (NAC).</p><p><strong>Methods: </strong>From January 2020 to December 2022, 104 newly diagnosed female patients (the number of people who met the inclusion criteria) with breast cancer who were confirmed to be preoperative NAC by puncture pathology were selected for a randomised single-blind trial. The patients were randomly divided into an observation group and a control group, with 52 cases in each group. The control group of patients received routine NAC treatment. The observation group played white noise at regular intervals every night on the basis of routine NAC, covering the entire treatment cycle. We evaluated the clinical efficacy, safety, sleep quality and immunological indicators of the two groups.</p><p><strong>Results: </strong>We found no statistically significant difference in the objective response rate between the two groups (P > 0.05). There was no statistically significant difference in the incidence of safety events between the two groups (P > 0.05). The total incidence of adverse reactions in the observation group was significantly lower than that in the control group (P < 0.05). After intervention, the sleep latency, subjective sleep quality, sleep duration, daytime function and sleep disorder scores of both groups decreased, and the observation group had significantly lower scores than the control group (P < 0.05). After intervention, both groups showed changes in immunoglobulin A (IgA), immunoglobulin G (IgG), immunoglobulin M (IgM), C-reactive protein and serum interleukin-6, but the differences between the groups were not statistically significant (P > 0.05).</p><p><strong>Conclusion: </strong>White noise intervention can improve the sleep quality of the NAC population with breast cancer and reduce the incidence of adverse reactions. In addition, it has no effect on the treatment efficacy, safety and immune indicators of patients.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 123","pages":"577-583"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142951038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-07-01Epub Date: 2024-09-30DOI: 10.4103/nah.nah_58_24
Yun Rong, Jingwen Jiang, Xueling Zhang, Yuntao Bu
{"title":"Application of Music Therapy in Improving Sleep Quality and Psychological Health of Pregnant Women with Hypertension: A Retrospective Study.","authors":"Yun Rong, Jingwen Jiang, Xueling Zhang, Yuntao Bu","doi":"10.4103/nah.nah_58_24","DOIUrl":"10.4103/nah.nah_58_24","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study was to retrospectively study the effect of music therapy on sleep quality and mental health level of pregnant women with hypertension in pregnancy (HIP).</p><p><strong>Methods: </strong>A total of 188 pregnant women with gestational hypertension admitted to The Fourth Hospital of Shijiazhuang from January 2022 to January 2023 were selected as the research objects. Based on various management methods documented in the medical record system, the individuals were divided into a control group (n = 88, routine management) and an observation group (n = 100, routine management + music therapy). The State-Trait Anxiety Inventory (STAI), Athens Insomnia Scale (AIS), and pregnancy outcomes were compared between the two groups.</p><p><strong>Results: </strong>No significant difference in the STAI and AIS scores before treatment was found between the two groups on admission (P > 0.05). The AIS and STAI scores in the observation group were lower than those in the control group 2 days after delivery (P < 0.05). The total incidence of adverse pregnancy outcomes in the observation group (8.00%) was lower than that in the control group (11.37%), but no significant difference between the two groups (P > 0.05).</p><p><strong>Conclusions: </strong>The implementation of music therapy for patients with HIP can alleviate their negative emotions to a certain extent and can improve sleep, offering certain clinical promotion value.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 122","pages":"332-337"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142350825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noise & HealthPub Date : 2024-07-01Epub Date: 2024-09-30DOI: 10.4103/nah.nah_60_24
Yan Yao, Lei Li
{"title":"Analysis of Therapeutic Options for Noise-Induced Hearing Loss: Retroauricular Injection of Methylprednisolone Sodium Succinate Combined with Hyperbaric Oxygenation.","authors":"Yan Yao, Lei Li","doi":"10.4103/nah.nah_60_24","DOIUrl":"10.4103/nah.nah_60_24","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the clinical effect of retroaural injection of methylprednisolone sodium succinate combined with hyperbaric oxygen (HBO) on the treatment of noise-induced hearing loss.</p><p><strong>Methods: </strong>Case data of 220 patients with hearing loss treated at the Zhongda Hospital Southeast University from January 1, 2019 to August 1, 2023 were obtained. As per the treatment plan, the recruited patients were divided into two cohorts: 158 cases in the combined-treatment group (retroaural injection of methylprednisolone sodium succinate combined with HBO) and 62 cases in the single-hormone group (retroaural injection of methylprednisolone sodium succinate). Comparison of the clinical efficacies and postoperative complication rates of the two groups was performed after treatment. MS-Excel was used to build a database for all data, and SPSS26.0 was utilized in the statistical analysis of recorded data.</p><p><strong>Results: </strong>For patients with low-frequency, high-frequency, and flat descending type, the combined-treatment group showed significantly higher clinical effective rate than the single-hormone group (P < 0.05). For patients with disease duration ≤7 days, the combined-treatment group attained a significantly higher clinical effective rate was than the single-hormone group (P < 0.05). The safety of patients in both groups was evaluated mainly through their adverse reactions. The total incidence of adverse reactions in the single-hormone group reached 9.68%, and that in the combined-treatment group was 8.23%. The two groups revealed no significant difference in terms of incidence of adverse reactions (P > 0.05).</p><p><strong>Conclusion: </strong>HBO combined with retroaural injection of methylprednisolone sodium succinate has good clinical efficacy and safety in the treatment of hearing loss.</p>","PeriodicalId":19195,"journal":{"name":"Noise & Health","volume":"26 122","pages":"370-375"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142350813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}