Northern Clinics of Istanbul最新文献_第3页

Sleeve gastrectomy in situsinversustotalis case. 袖带胃切除术治疗坐位性全胃炎。

IF 1

Northern Clinics of Istanbul Pub Date : 2023-11-21 eCollection Date: 2023-01-01 DOI: 10.14744/nci.2022.15046

Mehmet Gencturk, Abdullah Sisik, Muhammed Said Dalkilic, Merih Yilmaz, Selim Sozen, Hasan Erdem

引用次数: 0

The relationship of pre-operative vitamin D and TSH levels with papillary thyroid cancer. 术前维生素D和促甲状腺激素水平与甲状腺乳头状癌的关系。

IF 1

Northern Clinics of Istanbul Pub Date : 2023-11-21 eCollection Date: 2023-01-01 DOI: 10.14744/nci.2022.09699

Mehmet Taner Unlu, Nurcihan Aygun, Ozan Caliskan, Adnan Isgor, Mehmet Uludag

{"title":"The relationship of pre-operative vitamin D and TSH levels with papillary thyroid cancer.","authors":"Mehmet Taner Unlu, Nurcihan Aygun, Ozan Caliskan, Adnan Isgor, Mehmet Uludag","doi":"10.14744/nci.2022.09699","DOIUrl":"10.14744/nci.2022.09699","url":null,"abstract":"Objective: Our goal in this study is to analyze the correlation between papillary thyroid cancer (PTC) with elevated thyroid-stimulating hormone (TSH) levels and deficiency of vitamin D.Methods: Patients who underwent thyroidectomy, also with available vitamin D test results preoperatively, were included in the study. The patients were separated into two different categories as having papillary thyroid carcinoma (Group 1), benign diseases (Group 2). According to the TSH (mUI/mL) level and vitamin D values, patients were categorized into four quarters.Results: Preoperatively, TSH level (mean±SDmUI/mL) was higher in Group 1 (2.04±1.55) compared to Group 2 (1.82±1.94) significantly (p=0.029). Preoperatively, vitamin D levels (mean±SD) were higher in Group 1 (15.88±10.88) than in Group 2 (12.94±10.26) significantly (p=0.011). There was no significant difference between Group 1 and Group 2 according to the vitamin D deficiency (65.5%, 72.8%; respectively (p=0.472)). When categorized with reference to pre-operative vitamin D levels, the proportion of patients in Group 2 and Category 1 was higher significantly (p=0.031).Conclusion: Although the pre-operative TSH level was significantly higher in papillary thyroid carcinoma than benign thyroid diseases, the categorical distributions of the patients according to the TSH value were similar and the TSH values overlapped. Pre-operative mean vitamin D levels were similar in both PTC and benign thyroid disease groups so PTC was not associated with vitamin D deficiency.","PeriodicalId":19164,"journal":{"name":"Northern Clinics of Istanbul","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10846581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76745136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SARS-COV-2 MRNA vaccine-associated cutaneous vasculitis. SARS-COV-2 MRNA 疫苗相关皮肤血管炎。

IF 1

Northern Clinics of Istanbul Pub Date : 2023-11-21 eCollection Date: 2023-01-01 DOI: 10.14744/nci.2022.22309

Vedat Bugra Erol, Meryem Can

引用次数: 0

The importance of inflammatory biomarkers in ischemic stroke patients with carotid artery stenosis. 颈动脉狭窄缺血性中风患者的炎症生物标志物的重要性。

IF 0.9

Northern Clinics of Istanbul Pub Date : 2023-11-20 eCollection Date: 2023-01-01 DOI: 10.14744/nci.2023.87003

Aysel Tekesin, Ahmet Batuhan Demiral, Ahmet Yildirim

{"title":"The importance of inflammatory biomarkers in ischemic stroke patients with carotid artery stenosis.","authors":"Aysel Tekesin, Ahmet Batuhan Demiral, Ahmet Yildirim","doi":"10.14744/nci.2023.87003","DOIUrl":"10.14744/nci.2023.87003","url":null,"abstract":"Objective: This study aims to investigate inflammatory markers and their relationship with the degree of stenosis in ischemic stroke patients with carotid artery stenosis.Methods: This retrospective case-control study was conducted with 70 newly diagnosed ischemic stroke patients and 70 age- and gender-matched healthy controls. Laboratory analyses were carried out including serum hemogram, biochemistry profiles, erythrocyte sedimentation rate, and C-reactive protein (CRP). Mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-high-density lipoprotein cholesterol ratio (MHR) values were calculated, and compared between the patients and healthy controls. Patients were divided into two groups according to the degree of arterial carotid stenosis. The degree of carotid stenosis was <50% in Group 1 and it was 50% and above in Group 2.Results: In the patient group, neutrophil, monocyte, MPV, CRP, sedimentation, MHR, PLR, and NLR levels were significantly higher than the control group. There was no significant correlation between the level of carotid stenosis and inflammatory biomarkers. There was a significant correlation between the presentation NIHSS value and CRP, PLR, and NLR values.Conclusion: Inflammatory biomarker values were higher in stroke patients with carotid artery stenosis than in healthy individuals. However, they should neither be used to predict the degree of carotid artery stenosis.","PeriodicalId":19164,"journal":{"name":"Northern Clinics of Istanbul","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10846580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73394732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Just a vitamin? Should cobalamin (Vitamin B12) levels be checked in children with neurological disadvantages? 只是一种维生素？有神经系统缺陷的儿童是否应该检查钴胺素（维生素 B12）水平？

IF 1

Northern Clinics of Istanbul Pub Date : 2023-11-20 eCollection Date: 2023-01-01 DOI: 10.14744/nci.2022.33279

Celebi Kocaoglu, Seyma Akturk

{"title":"Just a vitamin? Should cobalamin (Vitamin B12) levels be checked in children with neurological disadvantages?","authors":"Celebi Kocaoglu, Seyma Akturk","doi":"10.14744/nci.2022.33279","DOIUrl":"10.14744/nci.2022.33279","url":null,"abstract":"Objective: The assay of serum cobalamin (Cbl) level is commonly used to diagnose Cbl deficiency. Unexpectedly, the elevated Cbl levels may be determined in some of the patients and its interpretation is difficult. We investigated the association between elevated Cbl levels and a variety of clinical entities in patients presenting with various neurological symptoms.Methods: The data were obtained from the patients' electronic medical records in a tertiary hospital affiliated with a university. The pediatric patients with serum Cbl levels above 1000 pg/mL were included in the study. The patients with serum Cbl levels below 900 pg/mL and above 200 pg/mL constituted the control group.Results: The mean Cbl level of the patients with neurological problems was 1424.2±354.2 pg/mL, whereas the average Cbl level of neurologically healthy was 1316±317.8 pg/mL, and the difference was statistically significant. While the rate of having neurological deficits or symptoms in the study group was found to be 24%, this rate was only 18% in the control group. Unexpectedly, despite elevated Cbl level, the high mean corpuscular volume rate was higher in the study group compared to the control group.Conclusion: This study highlights the importance of the disorders of Cbl metabolism in patients presenting with various neurological symptoms. In children with neurological deficits, serum Cbl levels should be checked. In case of high Cbl level is determined, patients should be followed up closely, and further investigations should be performed in terms of Cbl metabolism disorders.","PeriodicalId":19164,"journal":{"name":"Northern Clinics of Istanbul","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10846572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88493548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An entity that should be kept in mind: Synchronous gastrointestinal stromal tumor encountered in resection materials obtained for the detection of intra-abdominal malignancies. 应牢记的一个实体：在检测腹腔内恶性肿瘤的切除材料中发现的同步胃肠道间质瘤。

IF 1

Northern Clinics of Istanbul Pub Date : 2023-11-06 eCollection Date: 2023-01-01 DOI: 10.14744/nci.2022.98623

Selma Sengiz Erhan, Gamze Kulduk, Arzu Dobral, Aytul Bugra

{"title":"An entity that should be kept in mind: Synchronous gastrointestinal stromal tumor encountered in resection materials obtained for the detection of intra-abdominal malignancies.","authors":"Selma Sengiz Erhan, Gamze Kulduk, Arzu Dobral, Aytul Bugra","doi":"10.14744/nci.2022.98623","DOIUrl":"10.14744/nci.2022.98623","url":null,"abstract":"Objective: Gastrointestinal stromal tumors (GISTs), often sporadic, arise from interstitial Cajal cells of the gastrointestinal tract or their stem cell-like precursors. Apart from tumor-associated syndromes, it has been reported that GISTs are also associated with other tumors. There is no clear information about the etiology of these synchronous tumors. In this study, we wanted to present the clinicopathological features of 13 cases diagnosed as synchronous GIST with other tumors.Methods: Demographic characteristics of the cases, risk of progressive disease score, tumor localization, size, and the mitotic activity of tumors along with survival status were evaluated.Results: Thirteen of 101 cases diagnosed with GIST had a primary tumor synchronous with GIST. Synchronous GISTs were located in the stomach and small intestine. Most of the cases were detected incidentally in the intraoperative and post-operative periods. Risk scores for progressive disease were categorized as low (n=1), very low (n=1), and no risk (n=11). Non-GIST tumors were located in the stomach, transverse colon, left colon, rectum, gallbladder, kidney, and retroperitoneal space. Histological tumor types were adenocarcinoma, diffuse large B-cell lymphoma, mesothelioma, and neuroendocrine tumor. Life expectancy was found to be significantly lower in synchronous GISTs.Conclusion: In cases operated for non-GIST tumors, the possibility of incidental detection of GIST should always be kept in mind.","PeriodicalId":19164,"journal":{"name":"Northern Clinics of Istanbul","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10846574/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78779940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of patients presenting with serum electrolyte imbalance in terms of the differential diagnosis of pseudohypoaldosteronism. 从假性醛固酮增多症的鉴别诊断角度分析血清电解质失衡患者。

IF 1

Northern Clinics of Istanbul Pub Date : 2023-11-06 eCollection Date: 2023-01-01 DOI: 10.14744/nci.2022.70105

Celebi Kocaoglu, Seyma Akturk

{"title":"Analysis of patients presenting with serum electrolyte imbalance in terms of the differential diagnosis of pseudohypoaldosteronism.","authors":"Celebi Kocaoglu, Seyma Akturk","doi":"10.14744/nci.2022.70105","DOIUrl":"10.14744/nci.2022.70105","url":null,"abstract":"Objective: The aim of this study was to contribute to the differential diagnosis of transient pseudohypoaldosteronism (t-PHA).Methods: Twenty-nine infants, younger than 24 weeks, and with high aldosterone levels were included in the study. The patients were divided into two groups as t-PHA and other diagnoses group. Of 29 patients, 18 were in the t-PHA group and 11 were in other diagnoses group.Results: The means aldosterone, plasma renin activities (PRA), adrenocorticotropic hormone (ACTH), cortisol, and 17-hydroxyprogesterone (17-OHP) of those with t-PHA were 138±92.8 ng/dL, 8.39±10.57 ng/mL/h, 26.86±19.56 ng/L, 19.44±21.84 μg/dL, and 7.66±10.71 ng/mL, respectively. In other diagnoses group, the mean level of aldosterone, PRA, ACTH, cortisol, and 17-OHP levels was 100.9±70 ng/dL, 5.49±8.41 ng/mL/h, 408.28±491.9 ng/L, 19.99±14.43 μg/dL, and 11.99±12.21 ng/mL, respectively. In the t-PHA group, the number of patients with high PRA was eight (50%), while the number of patients with high levels was two (18.1%) in other diagnoses group. In the t-PHA group, although the average serum K levels were the same in both groups, serum aldosterone/K ratios were higher.Conclusion: When an infant younger than 24 weeks, with urinary tract infection and/or urinary tract malformation has electrolyte abnormalities, pediatricians should primarily consider the diagnosis of t-PHA. Thus, many unnecessary investigations and inappropriate treatments can be avoided.","PeriodicalId":19164,"journal":{"name":"Northern Clinics of Istanbul","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10846578/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77008016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suicide attempts and the factors that lead to suicidal ideation: A 3-year analysis. 自杀未遂和导致自杀意念的因素：三年分析。

IF 1

Northern Clinics of Istanbul Pub Date : 2023-11-06 eCollection Date: 2023-01-01 DOI: 10.14744/nci.2023.81598

Adem Az, Cigdem Orhan, Ozgur Sogut

{"title":"Suicide attempts and the factors that lead to suicidal ideation: A 3-year analysis.","authors":"Adem Az, Cigdem Orhan, Ozgur Sogut","doi":"10.14744/nci.2023.81598","DOIUrl":"10.14744/nci.2023.81598","url":null,"abstract":"Objective: We explored the epidemiological characteristics of suicide attempts and identified suicide trends and associated factors.Methods: This retrospective, cross-sectional, observational, and single-center study included consecutive 412 patients who were admitted to Emergency Department for follow-up and treatment after a suicide attempt between June 2019 and June 2022. We assessed patient demographics, suicidal behavior, previous suicide attempts, psychiatric disorders, drug use, visits to the psychiatry clinic within the past 6 months, the persistence of suicidal ideation, and clinical outcomes.Results: The study population consisted of 259 females (62.86%) and 153 males (37.14%), with a mean age of 29.50±11.51 (range: 13-72) years. Females attempted suicide more often than males, but suicide completion was more common in males. Overall, 79.37% (n=327) of the suicide attempters were aged <40 years and most were 20-29 years old (n=147, 35.68%). Non-fatal suicide attempts were more common in single, unemployed, and poorly educated individuals, but this was not the case for suicide completers. However, there was no significant difference in marital status, education, and occupation among suicide completers. Drug poisoning was the major form of suicide attempt (n=345, 83.74%). Mental disorders, family or relationship conflicts, and separation from a partner were common causes of suicidal ideation. Patient numbers were particularly high in the autumn (i.e., September), and at night.Conclusion: Females, young adults, singletons, the unemployed, and individuals with psychiatric disorders and low education levels are more likely to attempt suicide, particularly during hours when they are likely to be alone.","PeriodicalId":19164,"journal":{"name":"Northern Clinics of Istanbul","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10846586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72452174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the trauma-specific frailty index in geriatric trauma patients according to the new World Health Organization age classification. 根据世界卫生组织新的年龄分类，评估老年创伤患者的创伤特异虚弱指数。

IF 1

Northern Clinics of Istanbul Pub Date : 2023-11-03 eCollection Date: 2023-01-01 DOI: 10.14744/nci.2022.65785

Rumeysa Sut, Adem Az, Sumeyye Cakmak, Ozgur Sogut

{"title":"Evaluation of the trauma-specific frailty index in geriatric trauma patients according to the new World Health Organization age classification.","authors":"Rumeysa Sut, Adem Az, Sumeyye Cakmak, Ozgur Sogut","doi":"10.14744/nci.2022.65785","DOIUrl":"10.14744/nci.2022.65785","url":null,"abstract":"Objective: We compared the 15-variable trauma-specific frailty index and traditional injury scoring systems to determine trauma severity and predict discharge disposition in geriatric trauma patients based on the old and new World Health Organization age classifications.Methods: This prospective, observational, single-center study included geriatric patients aged ≥65 years with blunt trauma. We categorized patients as elderly based on the old or new World Health Organization age classification into group I (aged 65-79 years) and group II (aged ≥a80 years), respectively. At admission, we used traditional injury scoring systems (e.g., the Glasgow coma scale, injury severity score, and revised trauma score) to determine trauma severity. We compared the Trauma-Specific Frailty Index and traditional injury scoring systems between the patient groups and evaluated them for correlations.Results: We included 169 geriatric patients (80 and 89 in groups I and II, respectively). The mean Trauma-Specific Frailty Index score was significantly higher among females than males (p=0.025) and group II than group I (p=0.021). No significant correlations were observed in terms of the Trauma-Specific Frailty Index and traditional injury scoring systems in both groups. The mean Trauma-Specific Frailty Index score was significantly different between the hospitalized and discharged patients in group I (p=0.005), but not in group II (p=0.526).Conclusion: The 15-variable Trauma-Specific Frailty Index score is superior to traditional injury scoring systems for managing and predicting discharge disposition in geriatric trauma patients aged 65-79 years.","PeriodicalId":19164,"journal":{"name":"Northern Clinics of Istanbul","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10846567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80862967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between insight level and clinical and familial features in pediatric obsessive-compulsive disorder. 小儿强迫症患者的洞察力水平与临床和家族特征之间的关系。

IF 0.9

Northern Clinics of Istanbul Pub Date : 2023-06-05 eCollection Date: 2023-01-01 DOI: 10.14744/nci.2021.91979

Dilsad Yildiz Miniksar, Busra Oz, Mikail Ozdemir, Tugba Yuksel

{"title":"Relationship between insight level and clinical and familial features in pediatric obsessive-compulsive disorder.","authors":"Dilsad Yildiz Miniksar, Busra Oz, Mikail Ozdemir, Tugba Yuksel","doi":"10.14744/nci.2021.91979","DOIUrl":"10.14744/nci.2021.91979","url":null,"abstract":"Objective: The aim of this study was to explore the relationship between insight level and clinical and familial psychiatric features of children with obsessive-compulsive disorder (OCD).Methods: Children's Yale-Brown Obsessive-Compulsive Scale-Symptom Checklist, 11th item of the Children's Yale-Brown Obsessive-Compulsive Scale, Wechsler Intelligence Scale for Children Revised Form, Affective Disorders and Schizophrenia for School Aged Children Present and Lifetime Version 1.0, and Structured Diagnostic Interview for Diagnostic and Statistical Manual of Mental Disorders-IV Axis I Disorders were applied to 92 pediatric OCD patients.Results: In this study, the prevalence of OCD in the first children of the family was high (41.3%), and low insight was significantly related with concomitant intellectual disability (p=0.003). The level of insight was high in patients with comorbid OCD spectrum disorders (p<0.001). Attention deficit and hyperactivity disorder (ADHD) was the most common psychiatric diagnosis accompanying OCD (19.5%). Among the obsession-compulsion subscales, the symmetry/hoarding was higher in males (p=0.046). OCD patients with a family history of major depressive disorder (MDD) had high ADHD comorbidity rates (p=0.038). In OCD patients, whose family had psychiatric disorders besides MDD and anxiety disorders, the diagnosis rate of intellectual disability was higher than other diagnoses (p<0.001).Conclusion: The sociodemographic, clinical, and familial features of pediatric OCD patients cannot be adequately clarified if the patient has limited insight. Therefore, the insight of children with OCD should be considered a range or continuity.","PeriodicalId":19164,"journal":{"name":"Northern Clinics of Istanbul","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/94/5c/NCI-10-289.PMC10331248.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9812400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0