女性毛窦疾病的血液参数和临床特征分析:疾病与多囊卵巢综合征之间是否存在联系?

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL
Banu Yigit, Rumeysa Kevser Liman, Gulhan Kilicarslan
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引用次数: 0

摘要

目的:毛窦病(Pilonidal sinus disease, PSD)是骶尾骨区常见疾病,女性发病率较男性低。本研究的目的是评估PSD女性的临床、血液学、生化和激素参数,并确定该疾病是否在临床和实验室结果异常中起主要作用。该研究也将PSD与多囊卵巢综合征(PCOS)之间的关联问题带到了最前沿。方法:前瞻性单中心研究包括患有PSD的女性,以及同样数量的健康女性作为对照组(每组50名女性)。收集了每位患者的病史,并对所有参与者进行了血液检查。超声成像评估卵巢。结果:两组年龄相符(p=0.124)。与对照组相比,患有PSD的女性肥胖和血脂异常的患病率明显更高(p=0.046, p=0.008)。研究组右卵巢体积显著高于对照组(p=0.028)。研究组中性粒细胞、c肽和促甲状腺激素的平均水平也显著高于对照组(p=0.047、p=0.031和p=0.048)。PSD患者PCOS患病率较高,但差异无统计学意义(32% vs 22%, p=0.26)。结论:根据我们的研究结果,一些临床和血液参数在有和没有PSD的女性之间有显著差异。虽然目前的研究显示PCOS的患病率在患有或不患有PSD的女性中没有显著差异,但还需要更全面和前瞻性的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis of blood parameters and clinical features in women with pilonidal sinus disease: Is there a link between the disease and polycystic ovary syndrome?

Objective: Pilonidal sinus disease (PSD) is a common disorder in the sacrococcygeal region and has a lower incidence in female as compared with male patients. The aim of this study is to evaluate clinical, hematological, biochemical, and hormonal parameters in women with PSD, and to determine whether the disease plays a major role in abnormalities of clinical and laboratory findings. This study also brings to the forefront the issue of the association between PSD and polycystic ovary syndrome (PCOS).

Methods: The prospective single-center study included women with PSD, and an equal number of healthy women enrolled in the control group (50 women in each arm of the study). Medical history was taken from every patient, and blood tests were performed on all participants. Ultrasound imaging was performed to evaluate the ovaries.

Results: Both groups were matched for age (p=0.124). The prevalence of obesity and dyslipidemia was significantly higher in women with PSD compared to controls (p=0.046, p=0.008, respectively). The right ovary volume was significantly higher in the study group than the control group (p=0.028). The study group had also significantly higher mean levels of neutrophil, C-peptide, and thyroid stimulating hormone (p=0.047, p=0.031, and p=0.048, respectively). The prevalence of PCOS was higher in patients with PSD, but the difference failed to reach statistical significance (32 vs. 22%, p=0.26).

Conclusion: Based on the findings of our study, some clinical and blood parameters differed significantly between women with and without PSD. Although the present study revealed that the prevalence of PCOS was not significantly different in women with or without PSD, more comprehensive and prospective studies are required.

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来源期刊
Northern Clinics of Istanbul
Northern Clinics of Istanbul MEDICINE, GENERAL & INTERNAL-
CiteScore
0.40
自引率
0.00%
发文量
48
审稿时长
10 weeks
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