Neuromodulation最新文献_第7页

Accelerative Effects of Transcutaneous Electrical Acustimulation on Postoperative Recovery After Thoracolumbar Vertebral Fracture Associated With Suppressed Sympathetic Activity and Interleukin-6 经皮电刺激对胸腰椎骨折术后恢复的促进作用与交感神经活动和白细胞介素-6抑制相关。

IF 3.2 3区医学

Neuromodulation Pub Date : 2025-06-01 DOI: 10.1016/j.neurom.2024.11.011

Ying Kang MD , Feng Xu MD , Yang Wang MD , Xiangyue Gao MD , Weixin Dong MD , Liansong Lu MD , Fei Li MD , Lin Lin PhD , Jiande D.Z. Chen PhD

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引用次数: 0

Tonic and Event-Related Phasic Transcutaneous Auricular Vagus Nerve Stimulation Alters Pupil Responses in the Change-Detection Task 紧张性和事件相关的相位经皮耳迷走神经刺激改变了变化检测任务中的瞳孔反应。

IF 3.2 3区医学

Neuromodulation Pub Date : 2025-06-01 DOI: 10.1016/j.neurom.2025.01.003

Jingxin Chen MD , Yufeng Ke PhD , Guangjian Ni PhD , Shuang Liu PhD , Dong Ming PhD

{"title":"Tonic and Event-Related Phasic Transcutaneous Auricular Vagus Nerve Stimulation Alters Pupil Responses in the Change-Detection Task","authors":"Jingxin Chen MD , Yufeng Ke PhD , Guangjian Ni PhD , Shuang Liu PhD , Dong Ming PhD","doi":"10.1016/j.neurom.2025.01.003","DOIUrl":"10.1016/j.neurom.2025.01.003","url":null,"abstract":"<div><h3>Background</h3><div>Transcutaneous auricular vagus nerve stimulation (taVNS) has emerged as a potential modulator of cognitive behavior by activating the locus ceruleus-noradrenaline (LC-NA) system. Previous studies explored both phasic and tonic taVNS by investigating their impact on LC-NA markers such as pupil dilation and heart rate variability (HRV).</div></div><div><h3>Objective</h3><div>Inconsistencies persist in the identification of reliable markers for assessing the effects of taVNS on noradrenergic activity. Furthermore, it remains unclear whether the effects of taVNS extend beyond pure vagal nerve responses, particularly in specific cognitive domains such as working memory. In the present study, we investigated the effects of taVNS on working memory capacity and LC-NA markers using a change-detection task.</div></div><div><h3>Materials and Methods</h3><div>Twenty-two healthy, right-handed university students participated in a sham-controlled, randomized cross-over experiment with four sessions. We applied two types of phasic and event-related stimulation (Pre-event and Event-synchronous), tonic stimulation (Pre-task), and sham stimulation across different sessions. Pupil size and electrocardiogram data were recorded during the tasks.</div></div><div><h3>Results</h3><div>taVNS did not significantly modulate behavioral performance on the change-detection task, specifically working memory capacity. However, both tonic and event-related phasic taVNS significantly influenced the pupillary response during the task. In addition, the Pre-task condition of the taVNS affected the low-frequency parameter of HRV.</div></div><div><h3>Conclusions</h3><div>Our findings suggest that tonic and event-related phasic taVNS may modulate noradrenergic activity, as evidenced by pupil responses and HRV changes during the change-detection task. This study provides new evidence regarding the impact of taVNS on cognitive tasks, thus supporting the development of noninvasive neuromodulation interventions.</div></div>","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Pages 652-662"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to: Anesthetic Effect on the Subthalamic Nucleus in Microelectrode Recording and Local Field Potential of Parkinson’s Disease 反应：麻醉对帕金森病丘脑下核微电极记录和局部场电位的影响

IF 3.2 3区医学

Neuromodulation Pub Date : 2025-06-01 DOI: 10.1016/j.neurom.2025.03.066

Cinira Diogo PhD , Christopher R. Conner MD, PhD

引用次数: 0

Response to: Letter to the Editor Regarding: “Anesthetic Effect on the Subthalamic Nucleus in Microelectrode Recording and Local Field Potential of Parkinson’s Disease” 回复：关于“帕金森病微电极记录和局部场电位麻醉对丘脑下核的影响”的致编辑信

IF 3.2 3区医学

Neuromodulation Pub Date : 2025-06-01 DOI: 10.1016/j.neurom.2025.03.067

Shin-Yuan Chen MD , Sheng-Huang Lin MD

引用次数: 0

28. Holistic composite assessments, arithmetic gymnastics to make sense of a complex outcome 28. 整体综合评估，算术体操，使复杂的结果有意义