Neuromodulation最新文献

{"title":"ID# 2183376 CERVICAL SPINAL CORD STIMULATOR LEAD MIGRATION CAUSING OCCIPITAL NEURALGIA: A CASE REPORT OF REVISION WITHOUT EXPLANTATION","authors":"Kevin Vincent Gilbert MD, MS, Gary Allen MD, Tyler Ball MD, Tigran Kesayan MD","doi":"10.1016/j.neurom.2026.06.042","DOIUrl":"10.1016/j.neurom.2026.06.042","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"29 7","pages":"Page e27"},"PeriodicalIF":3.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149094602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ID# 2186426 SYMPTOM IMPROVEMENT IN CHRONIC SUBJECTIVE TINNITUS AFTER TRANSCRANIAL MAGNETIC STIMULATION: A RETROSPECTIVE OPEN-LABEL STUDY","authors":"Abhinav Singh Verma MD, Bhavik Bansal MD, Rishab Gupta MD, Nand Kumar MD, Anjali Pathak MD, Vaibhav Patil MD","doi":"10.1016/j.neurom.2026.06.049","DOIUrl":"10.1016/j.neurom.2026.06.049","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"29 7","pages":"Page e31"},"PeriodicalIF":3.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149094601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ID# 2184740 FOCUSED ULTRASOUND NONINVASIVELY AND REVERSIBLY IMPROVES SPASTICITY AFTER SPINAL CORD INJURY IN MOUSE MODELS","authors":"Joshua Chalif MD, PhD, Chen Gong MS, Zhigang He PhD, Yi Lu MD PhD, Qifa Zhou PhD","doi":"10.1016/j.neurom.2026.06.045","DOIUrl":"10.1016/j.neurom.2026.06.045","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"29 7","pages":"Page e29"},"PeriodicalIF":3.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149093729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ID# 2173133 SURGICAL PADDLE LEAD TRIAL FOR SPINAL CORD STIMULATION: RETROSPECTIVE CASE SERIES FROM A SINGLE-SURGEON DATA BASE","authors":"Griffin W. White BS, Stephen Jaffee MD, Varun Nayar BS, Michael Patterson MD, Nestor D. Tomycz MD","doi":"10.1016/j.neurom.2026.06.024","DOIUrl":"10.1016/j.neurom.2026.06.024","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"29 7","pages":"Page e16"},"PeriodicalIF":3.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149094026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ID# 2157292 LATERAL SACROILIAC JOINT FUSION PLANNING: EXPANDED PILOT STUDY USING COMPUTED TOMOGRAPHY ANGIOGRAPHIC ANALYSIS","authors":"Christopher J. Mallard MD, Jay S. Grider DO, PhD, MBA, Michael E. Harned MD","doi":"10.1016/j.neurom.2026.06.005","DOIUrl":"10.1016/j.neurom.2026.06.005","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"29 7","pages":"Page e4"},"PeriodicalIF":3.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ID# 2175848 PERCUTANEOUS 60-DAY PERIPHERAL NERVE STIMULATION PROVIDES DURABLE RELIEF FROM OCCIPITAL HEADACHE: A PROSPECTIVE, SINGLE-ARM STUDY","authors":"Christopher A. Gilmore Sr. MD, Zachary McCormick MD, Genaro Gutierrez MD, Mitchell Engle MD, Matthew Pingree MD, Jason Pope MD, David DiBennedetto MD, Narayan Kissoon MD, William J. Huffman PhD, Nathan Crosby PhD, Joseph Boggs PhD","doi":"10.1016/j.neurom.2026.06.028","DOIUrl":"10.1016/j.neurom.2026.06.028","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"29 7","pages":"Page e18"},"PeriodicalIF":3.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ID# 2171339 MULTIDIMENSIONAL OUTCOMES OF SPINAL CORD STIMULATION: A PROSPECTIVE MULTICENTER OBSERVATIONAL STUDY","authors":"Simon Thomson MBBS, Laura Demartini MD, Kliment Gatzinsky MD, PhD, Jan Willem Kallewaard MD, PhD, Georgios Matis MD, Agustin Mendiola MD, Concepcion Perez MD, Ganesan Baranidharan MD, Simon Bayerl MD, Borja Bujedo MD, Jorge Calle MD, Jose de Andres MD, PhD, Sarah Love-Jones MD, Vivek Mehta MBBS, MD, Nicolas Verela MD, Jan Vesper MD, PhD","doi":"10.1016/j.neurom.2026.06.020","DOIUrl":"10.1016/j.neurom.2026.06.020","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"29 7","pages":"Page e13"},"PeriodicalIF":3.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ID# 2171340 HOLISTIC SPINAL CORD STIMULATION APPROACH TREATING PAINFUL DIABETIC PERIPHERAL NEUROPATHY: OUTCOMES FROM THE INSPIRE STUDY","authors":"Cristian Rizea MD, Jose Paz-Solis MD, Maria R. de Aragon MD, Javier D. de Teran MD, Gerardo J. Gutierrez MD, Ismael Huertas PhD, Beatriz R. Mansilla MD, Rafael J. Martinez MD, Cristian Rizea MD, Heleen Scholtes MS","doi":"10.1016/j.neurom.2026.06.021","DOIUrl":"10.1016/j.neurom.2026.06.021","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"29 7","pages":"Page e14"},"PeriodicalIF":3.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing Percutaneous Tibial Nerve Stimulation Intensity for Overactive Bladder Using a Motion Capture System","authors":"Linquan Jin MM,&nbsp;Dongsheng Shang MM,&nbsp;Han Deng MD,&nbsp;Chen Li MD,&nbsp;Ziyu Wang MD,&nbsp;Hao Li BE,&nbsp;Limin Liao MD, PhD,&nbsp;Yun Guo MD,&nbsp;Xing Li MD, PhD","doi":"10.1016/j.neurom.2026.06.481","DOIUrl":"10.1016/j.neurom.2026.06.481","url":null,"abstract":"<div><h3>Background and Objective</h3><div>Overactive bladder (OAB) is a significant global health issue. The standard percutaneous tibial nerve stimulation (PTNS) protocol uses maximal-tolerance stimulation and causes discomfort and other side effects. This study aimed to optimize stimulation intensity using a motion capture (MoCap) system, thereby enhancing therapy safety and personalization.</div></div><div><h3>Materials and Methods</h3><div>In a single short-term stimulation session, the stimulator was fixed to the cat’s (four males and four females) medial malleolus and the inertial measurement unit (IMU) sensor to the ipsilateral paw dorsum. Threshold intensity T was established conventionally by visual observation of toe flexion, and t was established through MoCap. The effects of PTNS on the micturition reflex were assessed using serial cystometrograms (CMGs) during infusion of normal saline (NS) or acetic acid (AA).</div></div><div><h3>Results</h3><div>During NS infusion, PTNS at 2T increased bladder capacity (BC) to 143.60% ± 4.96% of control (9.89 ± 3.20 mL) and at 2t increased it to 143.10% ± 5.81% (both <em>p</em> &lt; 0.01). During AA infusion, BC decreased to 56.43% ± 1.59% of control (<em>p</em> &lt; 0.01); subsequent PTNS at 2T and at 2t restored it to 77.99% ± 4.80% and 78.08% ± 4.65%, respectively (both <em>p</em> &lt; 0.01). MoCap t was significantly lower than T (<em>p</em> &lt; 0.05). Both intensities prolonged contraction duration relative to the AA group (<em>p</em> &lt; 0.05), whereas contraction amplitude and area under the curve did not differ among conditions (<em>p</em> &gt; 0.05). Angular velocity and linear acceleration across all three orthogonal axes showed moderately to highly significant positive correlations with stimulation intensity.</div></div><div><h3>Conclusions</h3><div>The IMU-based MoCap system used angular velocity and linear acceleration as measures and identified a markedly lower stimulation threshold that produced therapeutic outcomes equivalent to conventional protocols. Although this single-session short-term study differs from standard longitudinal clinical application, this approach reduces stimulation intensity and may enable safer and more individualized PTNS for OAB.</div></div>","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"29 7","pages":"Pages 1292-1299"},"PeriodicalIF":3.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148674015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electro-Mechanical Mapping of the Small Intestine and the Influence of High-Energy Pacing","authors":"Nipuni D. Nagahawatte PhD,&nbsp;Shaleka Agrawal PhD,&nbsp;Hanyu Zhang PhD,&nbsp;Jack M. Rogers PhD,&nbsp;Recep Avci PhD,&nbsp;Peng Du PhD,&nbsp;Niranchan Paskaranandavadivel PhD,&nbsp;Leo K. Cheng PhD","doi":"10.1016/j.neurom.2025.07.003","DOIUrl":"10.1016/j.neurom.2025.07.003","url":null,"abstract":"<div><h3>Purpose</h3><div>Compromised electrical and mechanical activity in the gastrointestinal tract is associated with several motility disorders. Conventional treatment fails in a significant proportion of the patient population, and pacing is a promising alternative therapy. However, the correlation between slow waves and contractions during pacing remains unexplored. Therefore, this study simultaneously mapped contractile and slow wave responses in high-resolution during pacing to elucidate their relationship and therapeutic implications.</div></div><div><h3>Materials and Methods</h3><div>Electrical and contractile activity were measured simultaneously in the jejunum of seven pigs in vivo. After a baseline session, pacing was applied at 10-second intervals with a pulse amplitude of 8 mA and pulse widths of either 100 or 400 milliseconds. Slow wave and contractile responses were quantified by the propagation pattern and strain.</div></div><div><h3>Results</h3><div>Pacing spatially entrained the slow wave activity, generating a radial pacemaker propagation pattern with a success of 89% at both the energy levels, and induced a localized ring contraction at the pacing site in response to each pacing pulse. Induced contractions had mean contractile strains of −0.15 ± 0.04 and −0.19 ± 0.05 when paced at 100 milliseconds and 400 milliseconds, respectively.</div></div><div><h3>Conclusions</h3><div>This study defined the spatial response of slow wave activity during pacing, while mapping contractile activity. Slow waves propagated radially in a pacemaker pattern, whereas contractions remained localized. This insight into electrophysiologic modulation during pacing warrants further investigation. These findings are significant because they correlate the electrical and mechanical responses during intestinal pacing and will help optimize pacing techniques as a novel therapy for motility disorders.</div></div>","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"29 7","pages":"Pages 1146-1154"},"PeriodicalIF":3.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}