Neuromodulation最新文献

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57. The UK&I National Neuromodulation Registry: intrathecal baclofen improves patient perception of spasticity but does not improve quality of life 57. UK&I国家神经调节登记处:鞘内巴氯芬可改善患者对痉挛的感知,但不能改善生活质量
IF 3.2 3区 医学
Neuromodulation Pub Date : 2025-06-01 DOI: 10.1016/j.neurom.2025.03.059
S. Martin , A. Papacharalampous , G. Baranidharan , S. Thomson , A. Gulve , V. Mehta , S. Love-Jones , R. Strachan , S. Eldabe , J.J. FitzGerald , S. Bojanić
{"title":"57. The UK&I National Neuromodulation Registry: intrathecal baclofen improves patient perception of spasticity but does not improve quality of life","authors":"S. Martin , A. Papacharalampous , G. Baranidharan , S. Thomson , A. Gulve , V. Mehta , S. Love-Jones , R. Strachan , S. Eldabe , J.J. FitzGerald , S. Bojanić","doi":"10.1016/j.neurom.2025.03.059","DOIUrl":"10.1016/j.neurom.2025.03.059","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S29"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144190020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
31. Mixed methods survey of stakeholders to identify barriers to accessing deep brain stimulation for movement disorders in Canada 31. 利益相关者的混合方法调查,以确定在加拿大获得深部脑刺激治疗运动障碍的障碍
IF 3.2 3区 医学
Neuromodulation Pub Date : 2025-06-01 DOI: 10.1016/j.neurom.2025.03.033
M. Lannon , A. Martyniuk , M. Aminnejad , R. Hatoum , D. Paoloni , F. Farrokhyar , M. Bhandari , S. Kalia , S. Sharma
{"title":"31. Mixed methods survey of stakeholders to identify barriers to accessing deep brain stimulation for movement disorders in Canada","authors":"M. Lannon , A. Martyniuk , M. Aminnejad , R. Hatoum , D. Paoloni , F. Farrokhyar , M. Bhandari , S. Kalia , S. Sharma","doi":"10.1016/j.neurom.2025.03.033","DOIUrl":"10.1016/j.neurom.2025.03.033","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S16"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
37. Outcomes of spinal cord stimulation in patients with non-surgical refractory back and/or lower extremity radicular pain: a single-centre, retrospective review 37. 脊髓刺激治疗非手术性难治性背痛和/或下肢神经根性疼痛的疗效:一项单中心回顾性研究
IF 3.2 3区 医学
Neuromodulation Pub Date : 2025-06-01 DOI: 10.1016/j.neurom.2025.03.039
V. Varshney , A. Stelzl , R. Sahjpaul , S. Paquette , J. Osborn
{"title":"37. Outcomes of spinal cord stimulation in patients with non-surgical refractory back and/or lower extremity radicular pain: a single-centre, retrospective review","authors":"V. Varshney , A. Stelzl , R. Sahjpaul , S. Paquette , J. Osborn","doi":"10.1016/j.neurom.2025.03.039","DOIUrl":"10.1016/j.neurom.2025.03.039","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S19"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
14. Waveform utilization and outcomes of spinal cord stimulation in CRPS patients: a multicenter real-world observational study 14. CRPS患者脊髓刺激的波形利用和结果:一项多中心现实世界观察研究
IF 3.2 3区 医学
Neuromodulation Pub Date : 2025-06-01 DOI: 10.1016/j.neurom.2025.03.016
A. Gulve , J. Robinson , I. Wilkinson , S. Raoul , P. Rigoard , J.E. Llopis , G. Kyriakopoulos , J. Paz-Solis , S. Bayer , S. Love-Jones , M.A.C. Verdecho , E. Goldberg
{"title":"14. Waveform utilization and outcomes of spinal cord stimulation in CRPS patients: a multicenter real-world observational study","authors":"A. Gulve , J. Robinson , I. Wilkinson , S. Raoul , P. Rigoard , J.E. Llopis , G. Kyriakopoulos , J. Paz-Solis , S. Bayer , S. Love-Jones , M.A.C. Verdecho , E. Goldberg","doi":"10.1016/j.neurom.2025.03.016","DOIUrl":"10.1016/j.neurom.2025.03.016","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S8"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2. A single centre experience of use of novel fast acting sub-perception therapy (FAST) to achieve rapid analgesia in chronic pain patients 2. 使用新型快速亚知觉疗法(fast)实现慢性疼痛患者快速镇痛的单中心经验
IF 3.2 3区 医学
Neuromodulation Pub Date : 2025-06-01 DOI: 10.1016/j.neurom.2025.03.004
D. Lowes, C. Patel
{"title":"2. A single centre experience of use of novel fast acting sub-perception therapy (FAST) to achieve rapid analgesia in chronic pain patients","authors":"D. Lowes, C. Patel","doi":"10.1016/j.neurom.2025.03.004","DOIUrl":"10.1016/j.neurom.2025.03.004","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S2"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
48 Real-world outcomes, implant and programming details, and user satisfaction of SCS for treatment of PSPS-2: results from a European Clinical Survey 48真实结果,植入物和编程细节,以及SCS治疗PSPS-2的用户满意度:来自欧洲临床调查的结果
IF 3.2 3区 医学
Neuromodulation Pub Date : 2025-06-01 DOI: 10.1016/j.neurom.2025.03.050
F.J. Castro Seoane , J.C. de la Pinta García , S. Du Four , L. Elzinga , J.M. López Millán , L. Nader Navarro , F.J. Sánchez Montero , I. Smet , J.M. Trinidad Martín-Arroyo , C. Simonelli , H. Hanbli , R. Buschman
{"title":"48 Real-world outcomes, implant and programming details, and user satisfaction of SCS for treatment of PSPS-2: results from a European Clinical Survey","authors":"F.J. Castro Seoane , J.C. de la Pinta García , S. Du Four , L. Elzinga , J.M. López Millán , L. Nader Navarro , F.J. Sánchez Montero , I. Smet , J.M. Trinidad Martín-Arroyo , C. Simonelli , H. Hanbli , R. Buschman","doi":"10.1016/j.neurom.2025.03.050","DOIUrl":"10.1016/j.neurom.2025.03.050","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S25"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
32. Multi-centre prospective cohort of intractable chronic low back pain patients treated with restorative neurostimulation – outcomes from 5-year data 32. 顽固性慢性腰痛患者接受恢复性神经刺激治疗的多中心前瞻性队列研究-来自5年数据的结果
IF 3.2 3区 医学
Neuromodulation Pub Date : 2025-06-01 DOI: 10.1016/j.neurom.2025.03.034
A. Gulve, ReActiv8-B trial investigators
{"title":"32. Multi-centre prospective cohort of intractable chronic low back pain patients treated with restorative neurostimulation – outcomes from 5-year data","authors":"A. Gulve, ReActiv8-B trial investigators","doi":"10.1016/j.neurom.2025.03.034","DOIUrl":"10.1016/j.neurom.2025.03.034","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S17"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accelerative Effects of Transcutaneous Electrical Acustimulation on Postoperative Recovery After Thoracolumbar Vertebral Fracture Associated With Suppressed Sympathetic Activity and Interleukin-6 经皮电刺激对胸腰椎骨折术后恢复的促进作用与交感神经活动和白细胞介素-6抑制相关。
IF 3.2 3区 医学
Neuromodulation Pub Date : 2025-06-01 DOI: 10.1016/j.neurom.2024.11.011
Ying Kang MD , Feng Xu MD , Yang Wang MD , Xiangyue Gao MD , Weixin Dong MD , Liansong Lu MD , Fei Li MD , Lin Lin PhD , Jiande D.Z. Chen PhD
{"title":"Accelerative Effects of Transcutaneous Electrical Acustimulation on Postoperative Recovery After Thoracolumbar Vertebral Fracture Associated With Suppressed Sympathetic Activity and Interleukin-6","authors":"Ying Kang MD ,&nbsp;Feng Xu MD ,&nbsp;Yang Wang MD ,&nbsp;Xiangyue Gao MD ,&nbsp;Weixin Dong MD ,&nbsp;Liansong Lu MD ,&nbsp;Fei Li MD ,&nbsp;Lin Lin PhD ,&nbsp;Jiande D.Z. Chen PhD","doi":"10.1016/j.neurom.2024.11.011","DOIUrl":"10.1016/j.neurom.2024.11.011","url":null,"abstract":"<div><h3>Objectives</h3><div>Gastrointestinal (GI) disturbance is a frequent complication in patients with thoracolumbar vertebral fracture (TVF). Transcutaneous electrical acustimulation (TEA) has been reported to effectively accelerate postoperative GI function recovery after abdominal surgery. This study aimed to investigate the effects of TEA on postoperative recovery and the associated mechanisms.</div></div><div><h3>Materials and Methods</h3><div>A total of 81 patients with TVF who underwent elective posterior pedicle screw fixation surgery were randomized to receive TEA or sham-TEA. TEA at ST36 or sham-TEA at nonacupoints was performed for one hour twice daily, from 24 hours before surgery to postoperative day (POD) 3. The effects were then assessed in the form of a diary at different time points.</div></div><div><h3>Results</h3><div>Compared with sham-TEA, TEA attenuated postoperative impairments associated with lower GI motility, including a reduction in time to defecation by 27.2% (<em>p</em> = 0.002 vs sham-TEA), time to first flatus by 17.2% (<em>p</em> = 0.027), an increase in the Bristol stool score (<em>p</em> = 0.014), and the number of spontaneous bowel movement (<em>p</em> = 0.009). TEA also relieved other GI symptoms including abdominal bloating on POD1 and POD4 (<em>p</em> &lt; 0.001 and <em>p</em> = 0.001, respectively), straining during defecation (<em>p</em> &lt; 0.001), and sensation of anorectal blockage during defecation (<em>p</em> = 0.02). Moreover, TEA reduced the visual analog scale wound pain score on POD1 (<em>p</em> = 0.026), POD2 (<em>p</em> &lt; 0.001), and POD3 (<em>p</em> &lt; 0.001), increased vagal activity, and decreased sympathetic activity (<em>p</em> &lt; 0.001), in addition to suppressing the serum level of norepinephrine on both POD1 (<em>p</em> = 0.047) and POD4 (<em>p</em> = 0.036). TEA caused a higher decrease from POD1 to POD4 in serum interleukin-6 (<em>p</em> = 0.011, vs sham-TEA). The use of TEA was an independent predictor of shortened time to first defecation.</div></div><div><h3>Conclusion</h3><div>Noninvasive TEA at ST36, in comparison with sham-TEA, is effective in promoting postoperative recovery in patients with TVF by enhancing vagal and suppressing sympathetic activities.</div></div><div><h3>Clinical Trial Registration</h3><div>The study was retrospectively registered on <span><span>www.chictr.org.cn</span><svg><path></path></svg></span> (Chinese Clinical Trial Registry ChiCTR2300078195).</div></div>","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Pages 690-699"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142966136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tonic and Event-Related Phasic Transcutaneous Auricular Vagus Nerve Stimulation Alters Pupil Responses in the Change-Detection Task 紧张性和事件相关的相位经皮耳迷走神经刺激改变了变化检测任务中的瞳孔反应。
IF 3.2 3区 医学
Neuromodulation Pub Date : 2025-06-01 DOI: 10.1016/j.neurom.2025.01.003
Jingxin Chen MD , Yufeng Ke PhD , Guangjian Ni PhD , Shuang Liu PhD , Dong Ming PhD
{"title":"Tonic and Event-Related Phasic Transcutaneous Auricular Vagus Nerve Stimulation Alters Pupil Responses in the Change-Detection Task","authors":"Jingxin Chen MD ,&nbsp;Yufeng Ke PhD ,&nbsp;Guangjian Ni PhD ,&nbsp;Shuang Liu PhD ,&nbsp;Dong Ming PhD","doi":"10.1016/j.neurom.2025.01.003","DOIUrl":"10.1016/j.neurom.2025.01.003","url":null,"abstract":"<div><h3>Background</h3><div>Transcutaneous auricular vagus nerve stimulation (taVNS) has emerged as a potential modulator of cognitive behavior by activating the locus ceruleus-noradrenaline (LC-NA) system. Previous studies explored both phasic and tonic taVNS by investigating their impact on LC-NA markers such as pupil dilation and heart rate variability (HRV).</div></div><div><h3>Objective</h3><div>Inconsistencies persist in the identification of reliable markers for assessing the effects of taVNS on noradrenergic activity. Furthermore, it remains unclear whether the effects of taVNS extend beyond pure vagal nerve responses, particularly in specific cognitive domains such as working memory. In the present study, we investigated the effects of taVNS on working memory capacity and LC-NA markers using a change-detection task.</div></div><div><h3>Materials and Methods</h3><div>Twenty-two healthy, right-handed university students participated in a sham-controlled, randomized cross-over experiment with four sessions. We applied two types of phasic and event-related stimulation (Pre-event and Event-synchronous), tonic stimulation (Pre-task), and sham stimulation across different sessions. Pupil size and electrocardiogram data were recorded during the tasks.</div></div><div><h3>Results</h3><div>taVNS did not significantly modulate behavioral performance on the change-detection task, specifically working memory capacity. However, both tonic and event-related phasic taVNS significantly influenced the pupillary response during the task. In addition, the Pre-task condition of the taVNS affected the low-frequency parameter of HRV.</div></div><div><h3>Conclusions</h3><div>Our findings suggest that tonic and event-related phasic taVNS may modulate noradrenergic activity, as evidenced by pupil responses and HRV changes during the change-detection task. This study provides new evidence regarding the impact of taVNS on cognitive tasks, thus supporting the development of noninvasive neuromodulation interventions.</div></div>","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Pages 652-662"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to: Anesthetic Effect on the Subthalamic Nucleus in Microelectrode Recording and Local Field Potential of Parkinson’s Disease 反应:麻醉对帕金森病丘脑下核微电极记录和局部场电位的影响
IF 3.2 3区 医学
Neuromodulation Pub Date : 2025-06-01 DOI: 10.1016/j.neurom.2025.03.066
Cinira Diogo PhD , Christopher R. Conner MD, PhD
{"title":"Response to: Anesthetic Effect on the Subthalamic Nucleus in Microelectrode Recording and Local Field Potential of Parkinson’s Disease","authors":"Cinira Diogo PhD ,&nbsp;Christopher R. Conner MD, PhD","doi":"10.1016/j.neurom.2025.03.066","DOIUrl":"10.1016/j.neurom.2025.03.066","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Pages 705-706"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144195486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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