Neuromodulation最新文献

{"title":"25. First long term objective quantification of multifidus activity during restorative stimulation - 18F-FDG PET/CT assessment of multifidus activity and radiomics-based heterogeneity analysis","authors":"K. Poply , A. Haroon , T. Wodehouse , B. Ganeshan , R. Endozo , B. Goss , V. Mehta","doi":"10.1016/j.neurom.2025.03.027","DOIUrl":"10.1016/j.neurom.2025.03.027","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S13"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of an Educational Curriculum for Implanting and Managing Vagus Nerve Stimulators for Epilepsy","authors":"David Bieber MD ,&nbsp;Kunal Gupta MD, PhD ,&nbsp;Rany Abdallah MD ,&nbsp;Alaa Abd-Elsayed MD ,&nbsp;Alyson Engle MD ,&nbsp;Irina Duff MD, PhD ,&nbsp;Duvan Hoffman MBA ,&nbsp;Hemant Kalia MD, MPH ,&nbsp;Joshua Rosenow MD ,&nbsp;Micheal Macken MD ,&nbsp;Ahmed M. Raslan MD ,&nbsp;Konstantin Slavin MD ,&nbsp;Amy Tennant NP ,&nbsp;Jeffrey S. Raskin MS, MD","doi":"10.1016/j.neurom.2024.12.008","DOIUrl":"10.1016/j.neurom.2024.12.008","url":null,"abstract":"<div><h3>Background</h3><div>Vagus nerve stimulation (VNS) devices are commonly used for extracranial neuromodulation of drug-resistant epilepsy. These devices are implanted by multiple surgical subspecialties and managed by practitioners with varying levels of epilepsy-specific expertise. The North American Neuromodulation Society (NANS) education committee presents a curriculum defining level-dependent recommendations within the six-core competency rubric for the implantation and management of VNS devices.</div></div><div><h3>Material and Methods</h3><div>A multidisciplinary (anesthesiology, neurology, neurosurgery, and physiatrists) and diverse (advanced practice providers, physicians, and surgeons) subcommittee of the NANS education committee met virtually over a year to develop a curriculum following the Accreditation Council for Graduate Medical Education (ACGME) core competencies. The subcommittee used a consensus approach, evidence-based development strategy; once completed, the VNS curriculum was approved by the NANS board.</div></div><div><h3>Results</h3><div>The subcommittee developed a VNS curriculum as a standard to be used for implanting surgeons, managing physicians, and advanced practice providers. The vertical orientation of the curriculum uses the ACGME educational core competencies framework; within this paradigm is a horizontal progression of skills with distinct competency groups for implanting surgeons and/or managing physicians. The horizontal progression defines the expected competence for early learner, advanced learner, and independent practitioner.</div></div><div><h3>Conclusion</h3><div>A NANS education subcommittee iteratively developed a VNS curriculum for defining progressive competence of myriad care providers, including clinicians and advanced practice providers, within the ACGME six core competencies.</div></div>","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Pages 551-557"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phase-Amplitude Coupling in Response to Transcutaneous Vagus Nerve Stimulation: Focus on Regions Implicated in Mood and Memory","authors":"Charlotte Keatch PhD ,&nbsp;Elisabeth Lambert PhD ,&nbsp;Will Woods PhD ,&nbsp;Tatiana Kameneva PhD","doi":"10.1016/j.neurom.2025.01.011","DOIUrl":"10.1016/j.neurom.2025.01.011","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate whether transcutaneous vagus nerve stimulation (tVNS) at different frequencies affects phase-amplitude coupling among regions of the brain linked to mood and memory disorders using simultaneous magnetoencephalography (MEG) in healthy participants.</div></div><div><h3>Materials and Methods</h3><div>Phase-amplitude coupling was measured among brain areas in response to different stimulation frequencies of tVNS using concurrent MEG and tVNS in 17 healthy participants. The 4 protocols were: 24 Hz cymba concha, 1 Hz cymba concha, PFM cymba concha, and 24 Hz ear lobe. A driven autoregressive method was used to estimate the coupling among brain areas in different physiological frequency bands in response to these protocols.</div></div><div><h3>Results</h3><div>Different tVNS stimulation protocols led to alterations in phase-amplitude coupling among multiple brain regions linked to mood and memory, notably the prefrontal cortex, hippocampus, and temporal pole. Stimulation delivered at 24 Hz was observed to decrease delta-gamma coupling within the temporal pole and cingulate cortex when contrasted with 24-Hz sham stimulation.</div><div>Increased alpha-gamma coupling was observed between the hippocampus and prefrontal cortex when contrasting 24 Hz with pulse-frequency–modulated stimulation. Finally, a comparison of 24-Hz with low-frequency 1-Hz stimulation showed an increase in theta-gamma coupling within the prefrontal cortex.</div></div><div><h3>Significance</h3><div>To our knowledge, this study represents the first attempt to quantify phase-amplitude coupling in response to tVNS and suggests that different stimulation frequencies can modulate coupling between different areas of the brain. Abnormal phase-amplitude coupling has been linked to multiple mood and memory disorders. Further investigations using different stimulation frequencies of tVNS to alter phase-amplitude coupling may lead to the development of tVNS as a therapeutic option for different medical conditions.</div></div>","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Pages 663-671"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143493059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"21. ECAPS closed loop spinal cord stimulation using different stimulation paradigms for the treatment of chronic intractable pain: a European study using the Product Surveillance Registry (PSR)","authors":"A. Gulve ,&nbsp;P. Pierlovisi ,&nbsp;H. Hanbli ,&nbsp;H. Van der Velden ,&nbsp;T. Weaver ,&nbsp;R. Buschman","doi":"10.1016/j.neurom.2025.03.023","DOIUrl":"10.1016/j.neurom.2025.03.023","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S11"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"43. Pulse dosing of high frequency spinal cord stimulation immediately following implant: efficacy and satisfaction","authors":"H. Watson,&nbsp;J. Jennings,&nbsp;M. Raneses-Jeffrey,&nbsp;K. Robertson,&nbsp;E. Davies,&nbsp;E. Harding,&nbsp;J. Titterington,&nbsp;S. Black,&nbsp;C. Montgomery,&nbsp;A. Whelan,&nbsp;G. Baranidharan","doi":"10.1016/j.neurom.2025.03.045","DOIUrl":"10.1016/j.neurom.2025.03.045","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S22"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"13. Closed loop spinal cord stimulation for controlling chronic pain conditions: a case series","authors":"M. Hassan,&nbsp;C. Gromley,&nbsp;P. Murphy","doi":"10.1016/j.neurom.2025.03.015","DOIUrl":"10.1016/j.neurom.2025.03.015","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S7"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"16. Deep brain stimulation for tremor management in Klinefelter syndrome: a systematic review and case report","authors":"R. Hazrati,&nbsp;B. Dabboucy,&nbsp;M. Prudhomme","doi":"10.1016/j.neurom.2025.03.018","DOIUrl":"10.1016/j.neurom.2025.03.018","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S9"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"62. Use of spinal cord stimulation for pancreatic divisum and sphincter of Oddi dysfunction (SOD)","authors":"D. Anwar,&nbsp;A. Khan,&nbsp;S. Balasubramanian,&nbsp;G. Vajramani","doi":"10.1016/j.neurom.2025.03.064","DOIUrl":"10.1016/j.neurom.2025.03.064","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S32"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"34. Neuromodulatory effects of targeted tDCS on cognitive source-monitoring processes in the superior temporal gyrus and dorsolateral prefrontal cortex","authors":"G. Sharma ,&nbsp;V. Chitturi ,&nbsp;V.K. Sharma ,&nbsp;R. Kathrotia ,&nbsp;P. Barde ,&nbsp;N. Parmar ,&nbsp;M. Sharma ,&nbsp;R.D. Singh","doi":"10.1016/j.neurom.2025.03.036","DOIUrl":"10.1016/j.neurom.2025.03.036","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S18"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"23. Externally powered SCS at C2 for refractory neuropathic occipital and facial pain","authors":"M. Macdonald,&nbsp;H. Bedran,&nbsp;E. Pereira,&nbsp;M. Tavakkoli","doi":"10.1016/j.neurom.2025.03.025","DOIUrl":"10.1016/j.neurom.2025.03.025","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 4","pages":"Page S12"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}