Jean-Baptiste Delmotte, Abdulkarim Tutakhail, Kahina Abdallah, Pauline Reach, Marguerite D'Ussel, Gael Deplanque, Hélène Beaussier, François Coudoré
{"title":"Electrochemical Skin Conductance as a Marker of Painful Oxaliplatin-Induced Peripheral Neuropathy.","authors":"Jean-Baptiste Delmotte, Abdulkarim Tutakhail, Kahina Abdallah, Pauline Reach, Marguerite D'Ussel, Gael Deplanque, Hélène Beaussier, François Coudoré","doi":"10.1155/2018/1254602","DOIUrl":"https://doi.org/10.1155/2018/1254602","url":null,"abstract":"<p><strong>Purpose: </strong>Oxaliplatin is a platinum compound widely used in gastrointestinal cancer treatment but produces dose-limiting peripheral neuropathy. New insights into oxaliplatin-induced peripheral neuropathy (OIPN) assessment are needed to detect more effectively this condition. In this context, we conducted Canaloxa study, a prospective preliminary clinical trial that aimed to investigate how Electrochemical Skin Conductance (ESC), a parameter used in small fiber neuropathy assessment, could be helpful in OIPN diagnosis.</p><p><strong>Methods: </strong>Cancer patients treated for at least three months with oxaliplatin and suffering from clinically OIPN were included. Electrochemical Skin Conductance, thermal thresholds, and neuropathic pain were assessed in all included patients.</p><p><strong>Results: </strong>During one year, 36 patients were included. The main result was the correlation between ESC and Neuropathic Pain Symptom Inventory score for hands (rho value = -0.69, <i>p</i> < 0.0001) and feet (rho value = -0.79, <i>p</i> < 0.0001). ESC values were lower in neuropathic patients with painful symptoms than in ones without painful symptoms (<i>p</i> = 0.0003 and <i>p</i> < 0.0001 for hands and feet, respectively). No correlation was observed between ESC and thermal thresholds.</p><p><strong>Conclusion: </strong>These preliminary data suggest that ESC could be a useful objective marker of painful oxaliplatin-induced neuropathy and could complement the use of subjective clinical scales. <i>This study was prospectively registered on clinicaltrials.gov</i> (NCT02827916) <i>before patient recruitment has begun</i>.</p>","PeriodicalId":19124,"journal":{"name":"Neurology Research International","volume":"2018 ","pages":"1254602"},"PeriodicalIF":1.5,"publicationDate":"2018-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/1254602","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36664790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Saeed Alqahtani, Ahmad Ayed Alshbriqe, Ahmed A Awwadh, Turki Ali Alyami, Mohammed Saad Alshomrani, Adel Alhazzani
{"title":"Prevalence and Risk Factors for Depression among Caregivers of Alzheimer's Disease Patients in Saudi Arabia.","authors":"Mohammed Saeed Alqahtani, Ahmad Ayed Alshbriqe, Ahmed A Awwadh, Turki Ali Alyami, Mohammed Saad Alshomrani, Adel Alhazzani","doi":"10.1155/2018/2501835","DOIUrl":"https://doi.org/10.1155/2018/2501835","url":null,"abstract":"<p><strong>Objectives: </strong>To identify prevalence and risk factors of depression among caregivers of Alzheimer' disease (AD) patients.</p><p><strong>Methods: </strong>In a cross-sectional study, 110 caregivers of AD patients participated in this study (51 males and 59 females). Patients data were obtained from patients' records at Aseer Central Hospital. Depression among caregivers was assessed by using the Hamilton Rating Scale for Depression.</p><p><strong>Results: </strong>The age of caregivers ranged from 17 to 85 years (Mean±SD: 41.1±14.0 years). Prevalence of depression among caregivers was 70%. Caregivers were mainly sons/daughters (69.1%) or spouses (11.8%). A total of 33 caregivers (30%) had mild depression while 44 (40%) had moderate depression. Prevalence of depression was significantly higher among caregivers of AD patients who were exposed to repeated falling down (p=0.003), but did not differ significantly among caregivers who were exposed to repeated pneumonia or getting lost. Caregivers' scores of depression positively correlated with duration of caregivers' daily stay with AD patients (r=0.272, p=0.004), but did not correlate significantly with either caregivers' age or patients' age. Moreover, caregivers' depression did not differ significantly according to their marital status, educational status, employment status, or monthly income.</p><p><strong>Conclusions: </strong>Prevalence of depression among AD caregiver is high. Risk factors for depression include patients' exposure to repeated falls and prolonged stay with patients. Therefore, psychiatric care should be provided to caregivers, home safety should be maintained to avoid falls, and several persons should interchangeably provide care to AD patients.</p>","PeriodicalId":19124,"journal":{"name":"Neurology Research International","volume":"2018 ","pages":"2501835"},"PeriodicalIF":1.5,"publicationDate":"2018-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/2501835","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36572982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of Patients' Adherence to Antiepileptic Medications at Dessie Referral Hospital, Chronic Follow-Up, South Wollo, Amhara Region, North East Ethiopia.","authors":"Gizachew Kassahun, Getachew Moges, Yitayew Demessie","doi":"10.1155/2018/5109615","DOIUrl":"https://doi.org/10.1155/2018/5109615","url":null,"abstract":"<p><p>An epileptic seizure is a clinical event presumed to result from an abnormal and excessive neuronal discharge. The clinical symptoms are paroxysmal and may include impaired consciousness and motor, sensory, autonomic, or psychic events perceived by the subject or an observer. Epilepsy occurs when 2 or more epileptic seizures occur unprovoked by any immediately identifiable cause. And in the majority of patients with epilepsy, antiepileptic drugs effectively control their illness. However, more than 30% of people with epilepsy do not attain full seizure control, even with the best available treatment regimen. The aim of this study is to assess self-reported adherence in adult patients with epilepsy and to identify potential barriers for nonadherence to antiepileptic drug treatment in Dessie Referral Hospital. A hospital based cross-sectional study was conducted using structured questionnaires including Morisky medication adherence scale and analysis was conducted descriptively using SPSS version 20. The level of nonadherence to antiepileptic medication regimens was 34.1%. The major reason for missing medication was forgetfulness 53.5%. And the most common side effect was sedation 56.2%. <i>Conclusion.</i> Majority of epileptic patients in Dessie Referral Hospital was adherent to their AEDs treatment and among the determinants of adherence assessed the level of education and the side effect of drugs showed statistical significance.</p>","PeriodicalId":19124,"journal":{"name":"Neurology Research International","volume":"2018 ","pages":"5109615"},"PeriodicalIF":1.5,"publicationDate":"2018-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/5109615","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36539682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephen Albano, Blake Berman, Glenn Fischberg, Javed Siddiqi, Bolin Liu, Yasir Khan, Atif Zafar, Syed A Quadri, Mudassir Farooqui
{"title":"Retrospective Analysis of Ventriculitis in External Ventricular Drains.","authors":"Stephen Albano, Blake Berman, Glenn Fischberg, Javed Siddiqi, Bolin Liu, Yasir Khan, Atif Zafar, Syed A Quadri, Mudassir Farooqui","doi":"10.1155/2018/5179356","DOIUrl":"https://doi.org/10.1155/2018/5179356","url":null,"abstract":"<p><strong>Background: </strong>Nosocomial EVD-related ventriculitis is a major complication and a significant cause of morbidity and mortality in critically ill neurological patients. Questions remain about best management of EVDs. The purpose of this study is to compare our incidence of ventriculitis to studies using different catheters and/or antibiotic coverage schemes and determine whether c-EVD with prolonged antibiotics given for the duration of drain placement is inferior to ac-EVD with pp-abx or ac-EVD with prolonged antibiotics for prevention of ventriculitis.</p><p><strong>Methods: </strong>A retrospective chart review of all patients who had EVDs placed from January 2010 through December 2015 at home institution was performed. Statistical analysis was performed using Fisher's exact test to compare incidence of ventriculitis identified in other studies with that of home institution.</p><p><strong>Results: </strong>The study included 107 patients, 66 (61.7%) males and 41 (38.3%) females. Average age was 56 years ranging from 18 to 95 years. Average length of drain placement was 7.8 days ranging from 2 to 23 days. Average length of drain placement in infected drains was 13.3 days ranging from 11 to 15 days. There were 3 cases with positive CSF cultures (<i>Staphylococcus haemolyticus</i> and <i>Staphylococcus epidermidis</i> x 2). There were 2 cases with a CSF having a positive gram stain but failed to yield any bacterial growth on culture and did not meet predefined criteria.</p><p><strong>Conclusions: </strong>The c-EVD with prolonged antibiotics given for the duration of drain placement is not inferior to ac-EVD with pp-abx or ac-EVD with prolonged antibiotics for prevention of ventriculitis. The c-EVD with prolonged antibiotics is superior to c-EVD with pp-abx and conventional EVD without antibiotics for prevention of ventriculitis. Selection should include considerations for antibiotic stewardship and cost effectiveness. Future studies should also utilize clinical and CSF profile criteria in addition to positive CSF cultures for identifying ventriculitis to prevent line colonization from classification as ventriculitis in analysis.</p>","PeriodicalId":19124,"journal":{"name":"Neurology Research International","volume":"2018 ","pages":"5179356"},"PeriodicalIF":1.5,"publicationDate":"2018-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/5179356","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36515473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Serotonin Reuptake Inhibitors in Obstructive Sleep Apnea: Associations in People with and without Epilepsy.","authors":"Jocelyn Y Cheng","doi":"10.1155/2018/7247605","DOIUrl":"https://doi.org/10.1155/2018/7247605","url":null,"abstract":"<p><strong>Purpose: </strong>Positive airway pressure remains the gold-standard treatment for OSA, but many are intolerant. The neurotransmitter serotonin is involved in respiratory control. Evidence exists for SRIs in reducing OSA severity in the general population and ictal hypoxemia and seizure-induced respiratory arrest in people with epilepsy (PWE). However, the association between SRIs and OSA severity has not been studied in populations consisting of both groups. This study aims to determine if SRIs are associated with OSA severity in both PWE and people without epilepsy (PWO) and whether differences exist between the two groups.</p><p><strong>Methods: </strong>A retrospective study of adults with OSA was conducted. Subjects were categorized as PWE or PWO and for the use (+SRI) or absence (-SRI) of an SRI. The primary outcome was OSA severity relative to SRI status. OSA severity as a function of SRI status was also compared between PWE and PWO and within the PWE and PWO cohorts. Oxygen saturation nadir was a secondary outcome measure. Statistical adjustment of pertinent characteristics was performed.</p><p><strong>Results: </strong>There were 125 subjects (57 PWE, 68 PWO, 80 -SRI, and 45 +SRI). +SRI was associated with reduced odds of severe compared to moderate OSA, in unadjusted and adjusted analysis. Compared to PWO, PWE demonstrated a more robust association between OSA severity and +SRI. When analyzed as separate cohorts, only PWE demonstrated reduced OSA severity, with adjustment for age (OR:0.140, CI:0.021-1.116, and p=0.042). Oxygen saturation nadir was not significant in any model.</p><p><strong>Conclusions: </strong>SRIs represent a potential treatment option for OSA and may demonstrate a more robust association with reduced OSA severity in PWE compared to PWO.</p>","PeriodicalId":19124,"journal":{"name":"Neurology Research International","volume":"2018 ","pages":"7247605"},"PeriodicalIF":1.5,"publicationDate":"2018-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/7247605","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36518381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Maximizing the Survival of Amyotrophic Lateral Sclerosis Patients: Current Perspectives.","authors":"Osama A Khairoalsindi, Ahmad R Abuzinadah","doi":"10.1155/2018/6534150","DOIUrl":"10.1155/2018/6534150","url":null,"abstract":"<p><p>Amyotrophic lateral sclerosis is a neurodegenerative disease that leads to loss of the upper and lower motor neurons. Almost 90% of all cases occur in the sporadic form, with the rest occurring in the familial form. The disease has a poor prognosis, with only two disease-modifying drugs approved by the United States Food and Drug Administration (FDA). The approved drugs for the disease have very limited survival benefits. Edaravone is a new FDA-approved medication that may slow the disease progression by 33% in a selected subgroup of ALS patients. This paper covers the various interventions that may provide survival benefits, such as early diagnosis, medications, gene therapy, stem cell therapy, diet, nutritional supplements, multidisciplinary clinics, and mechanical invasive and noninvasive ventilation. The recent data on masitinib, the role of enteral feeding, gene therapy, and stem cell therapy is discussed.</p>","PeriodicalId":19124,"journal":{"name":"Neurology Research International","volume":"2018 ","pages":"6534150"},"PeriodicalIF":1.5,"publicationDate":"2018-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36443797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hanan Amer, Hatem Shehata, Laila Ahmed Rashed, Hanan Helmy, Shaimaa El-Jaafary, Asmaa Sabbah, Wael Ibrahim
{"title":"Genetic Influences on Cognition in Idiopathic Parkinson's Disease.","authors":"Hanan Amer, Hatem Shehata, Laila Ahmed Rashed, Hanan Helmy, Shaimaa El-Jaafary, Asmaa Sabbah, Wael Ibrahim","doi":"10.1155/2018/5603571","DOIUrl":"https://doi.org/10.1155/2018/5603571","url":null,"abstract":"Cognitive impairment in Parkinson's disease was clearly reported in the medical literature [1, 2]. This impairment is common to some degree even in nondemented Parkinson’s disease patients (PD-ND) and eventually progresses to dementia in 24 to 31% of patients [3]. The cognitive changes in PD are characterized by a frontalsubcortical impairment with decreased attention and executive function leading to progressive impairment in prefrontal tasks, visuospatial skills, and memory. Still, 20 to 25% of PDND patients may exhibit a pattern of cortical impairment with memory tasks and confrontation naming defects, and cognitive findings associated with cortical pathology, such as language errors, develop in many patients with PD with dementia (PDD) [4]. The identification of the biomarkers for cognitive impairment in patients with PD will allow better assessment of the patients' prognosis. Some genes, such as apolipoprotein E (ApoE) and microtubule-associated protein tau (MAPT), are of particular interest because of their known association with dementia in other neurodegenerative diseases, such as Alzheimer’s disease (AD) and atypical parkinsonian syndromes, including progressive supranuclear palsy and corticobasal degeneration (Morley et al., 2012) [5]. The aim of this study is to determine the role of genetic factors associated with cognitive decline in Parkinson’s disease (PD). We examined whether variations in apolipoprotein E (ApoE) and microtubule-associated protein tau (MAPT) genotypes are associated with cognitive decline in PD.","PeriodicalId":19124,"journal":{"name":"Neurology Research International","volume":"2018 ","pages":"5603571"},"PeriodicalIF":1.5,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/5603571","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36438445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of Stroke Risk Factors and Their Distribution Based on Stroke Subtypes in Gorgan: A Retrospective Hospital-Based Study-2015-2016.","authors":"Mahdi Habibi-Koolaee, Leila Shahmoradi, Sharareh R Niakan Kalhori, Hossein Ghannadan, Erfan Younesi","doi":"10.1155/2018/2709654","DOIUrl":"https://doi.org/10.1155/2018/2709654","url":null,"abstract":"<p><strong>Background: </strong>Stroke is a leading cause of death and disability worldwide. According to the Iranian Ministry of Medical Health and Education, out of 100,000 stroke incidents in the country, 25,000 lead to death. Thus, identifying risk factors of stroke can help healthcare providers to establish prevention strategies. This study was conducted to investigate the prevalence of stroke risk factors and their distribution based on stroke subtypes in Sayad Shirazi Hospital, Gorgan, Northeastern Iran.</p><p><strong>Material and methods: </strong>A retrospective hospital-based study was conducted at Sayad Shirazi Hospital in Gorgan, the only referral university hospital for stroke patients in Gorgan city. All medical records with a diagnosis of stroke were identified based on the International Classification of Diseases, Revision 10, from August 23, 2015, to August 22, 2016. A valid and reliable data gathering form was used to capture data about demographics, diagnostics, lifestyle, risk factors, and medical history.</p><p><strong>Results: </strong>Out of 375 cases, two-thirds were marked with ischemic stroke with mean ages (standard deviation) of 66.4 (14.2) for men and 64.6 (14.2) for women. The relationship between stroke subtypes and age groups (P=0.008) and hospital outcome (P=0.0001) was significant. Multiple regression analysis showed that hypertension (Exp. (B) =1.755, P=0.037), diabetes mellitus (Exp. (B) =0.532, P=0.021), and dyslipidemia (Exp. (B) =2.325, P=0.004) significantly increased the risk of ischemic stroke.</p><p><strong>Conclusion: </strong>Overall, hypertension, diabetes mellitus, and dyslipidemia were the major risk factors of stroke in Gorgan. Establishment of stroke registry (population- or hospital-based) for the province is recommended.</p>","PeriodicalId":19124,"journal":{"name":"Neurology Research International","volume":"2018 ","pages":"2709654"},"PeriodicalIF":1.5,"publicationDate":"2018-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/2709654","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36431769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Gravity and Task Specific Training of Elbow Extensors on Upper Extremity Function after Stroke.","authors":"Mohamed E Khallaf","doi":"10.1155/2018/4172454","DOIUrl":"10.1155/2018/4172454","url":null,"abstract":"<p><strong>Background: </strong>In individuals with hemiparetic stroke, reaching with the paretic arm can be impaired by abnormal muscle coactivation. Prior trails for improving upper extremity functions after stroke have underestimated the role of gravitational force in motor planning and execution.</p><p><strong>Objective: </strong>The aims this trial were to study the effect of gravity as a facilitator for elbow extension and to estimate the immediate and retention effects of task specific training of elbow extensors on upper extremity function after stroke.</p><p><strong>Methods: </strong>Twenty-six right handed patients with first ever stroke represented the sample of the study. The participants were randomly assigned into two equal groups. The study group received treatment through two phases. Phase one included training for the elbow extensors in an antigravity position. Phase two included a set of task specific exercise for 16 weeks. The control group received traditional passive stretch and range of motion exercises. Manual dexterity and upper limb function were assessed by Nine-Hole Peg Test and Fugl-Meyer upper extremity. Goniometry was used for measuring elbow extension and forearm supination active ranges of motion.</p><p><strong>Results: </strong>Significant improvements were observed in Nine-Hole Peg Test, Fugl-Meyer upper extremity, and ranges of motion at postintervention and follow-up compared to preintervention at P≤0.05.</p><p><strong>Conclusions: </strong>The results of this study provide an evidence that antigravity positions can be used as a centrally presented facilitator of elbow extension. Additionally, task specific training was effective in improving upper extremity function and elbow extension range of motion.</p>","PeriodicalId":19124,"journal":{"name":"Neurology Research International","volume":"2018 ","pages":"4172454"},"PeriodicalIF":1.5,"publicationDate":"2018-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36401374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cansu Köseoğlu Toksoy, Cem Bölük, Ülkü Türk Börü, Seydahmet Akın, Abdullah Yasir Yılmaz, Sanem Coşkun Duman, Mustafa Taşdemir
{"title":"Stroke Prevalence in a Coastal Town on the Black Sea Coast in Turkey: Community Based Study.","authors":"Cansu Köseoğlu Toksoy, Cem Bölük, Ülkü Türk Börü, Seydahmet Akın, Abdullah Yasir Yılmaz, Sanem Coşkun Duman, Mustafa Taşdemir","doi":"10.1155/2018/8246123","DOIUrl":"10.1155/2018/8246123","url":null,"abstract":"<p><strong>Background: </strong>This study aims to determine the stroke prevalence in Akçakoca which is a rural area in Turkey.</p><p><strong>Methods: </strong>The study was designed as a cross-sectional, door-to-door survey. The stroke questionnaire was completed by a trained team in the presence of the participants according to their answers. Based on the screenings, patients who had been diagnosed with stroke previously were reexamined by a neurologist and determined the prevalence values, risk factors, and stroke types.</p><p><strong>Results: </strong>A total of 3750 people over 44 years old were reached in the screenings. It was determined that 83 people had previously suffered a stroke. The prevalence rate of stroke in those above 44 years was found to be 2.2 (98% confidence level and ± 2% margin of error). 70 (84.3%) patients had suffered an ischemic stroke while 12 (14.5%) had suffered a hemorrhagic stroke. Male/female ratio was 1.1.</p><p><strong>Conclusion: </strong>The results of this study give the prevalence rate of stroke among the Turkish population living in a rural area. Due to a lack of other similar studies, it is impossible to make any data comparison. However, the results of this study help shed light on the stroke prevalence rate.</p>","PeriodicalId":19124,"journal":{"name":"Neurology Research International","volume":"2018 ","pages":"8246123"},"PeriodicalIF":1.5,"publicationDate":"2018-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/8246123","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36352830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}