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Clinical Immunology & Research最新文献

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The Brazilian National Immunization Program and Its Challenges for Modernization and Improvement 巴西国家免疫规划及其现代化和改进的挑战
Clinical Immunology & Research Pub Date : 2018-06-15 DOI: 10.33425/2639-8494.1012
R. Bordinhão
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引用次数: 0
Gluten Fibromyalgia 谷蛋白纤维肌痛
Clinical Immunology & Research Pub Date : 2018-06-15 DOI: 10.33425/2639-8494.1009
D. Labunskiy, S. Kopishinskaya
{"title":"Gluten Fibromyalgia","authors":"D. Labunskiy, S. Kopishinskaya","doi":"10.33425/2639-8494.1009","DOIUrl":"https://doi.org/10.33425/2639-8494.1009","url":null,"abstract":"","PeriodicalId":191133,"journal":{"name":"Clinical Immunology & Research","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121659834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Th1 and Th2 Cytokines Pattern among Sickle Cell Disease Patients in Côte d’ivoire Côte科特迪瓦镰状细胞病患者Th1和Th2细胞因子模式
Clinical Immunology & Research Pub Date : 2018-06-15 DOI: 10.33425/2639-8494.1011
L. Siransy, C. Yapo-Crezoit, M. Diané, Sidonie Goore, S. Kaboré, B. Koffi-Kabran, S. Konaté
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引用次数: 2
Therapeutic Use of MicroRNAs to Prevent and Control Allergic Rhinosinusitis microrna在预防和控制变应性鼻窦炎中的治疗应用
Clinical Immunology & Research Pub Date : 2018-06-15 DOI: 10.33425/2639-8494.1010
G. Gilbert
{"title":"Therapeutic Use of MicroRNAs to Prevent and Control Allergic Rhinosinusitis","authors":"G. Gilbert","doi":"10.33425/2639-8494.1010","DOIUrl":"https://doi.org/10.33425/2639-8494.1010","url":null,"abstract":"Inflammatory upper airway diseases, particularly chronic rhinosinusitis (CRS) and allergic rhinitis (AR), have a high worldwide prevalence. CRS and AR involve sustained and exaggerated inflammation that is associated with marked changes in gene and protein expression under tight regulation. miRNAs represent one of the fundamental epigenetic regulatory mechanisms used by cells that can mediate posttranscriptional gene silencing of target genes. As fine-tuning regulators of gene expression, miRNAs are involved in diverse biological processes, including cell proliferation, apoptosis, and differentiation, organ development, metabolism, stress responses, and signal transduction. Emerging evidence implicates an involvement of miRNAs in shaping the inflammation pattern in upper airways. Studies regarding the roles of miRNAs in allergic diseases have multiplied during the last 4 years, and the functions of miRNAs in the regulation and pathogenesis of these diseases are better and better characterized. Recently, miRNAs have been shown to be detectable in cell-free body fluids such as serum and plasma samples. The circulating miRNAs are protected from blood RNAs either by existing in cell membrane-derived vesicles such as exosomes or by forming a complex with lipid-protein carriers such as high-density lipoprotein. So it becomes possible to use such kind of molecules for a therapeutic purpose, and this is achieved by the Bio Immun(G)en Medicine – BI(G)MED – by introducing high diluted microRNAs in nanocompounds looking for a fine regulation in different upper airways diseases with an allergic aetiology.","PeriodicalId":191133,"journal":{"name":"Clinical Immunology & Research","volume":"101 36","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120826037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Health System- Related Barriers to the Uptake of Vct Services in a Rural Setting, a Case of Chivuna Southern Province 与卫生系统相关的障碍在农村环境中吸收Vct服务，奇武那南部省的一个案例
Clinical Immunology & Research Pub Date : 2018-06-15 DOI: 10.33425/2639-8494.1013
H. Ntalasha, Record Jacob Malungo, S. Simona, Sonja Merten
{"title":"Health System- Related Barriers to the Uptake of Vct Services in a Rural Setting, a Case of Chivuna Southern Province","authors":"H. Ntalasha, Record Jacob Malungo, S. Simona, Sonja Merten","doi":"10.33425/2639-8494.1013","DOIUrl":"https://doi.org/10.33425/2639-8494.1013","url":null,"abstract":"","PeriodicalId":191133,"journal":{"name":"Clinical Immunology & Research","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131241120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Travel & Edible Vaccines 旅游和食用疫苗
Clinical Immunology & Research Pub Date : 2018-06-15 DOI: 10.33425/2639-8494.1015
R. S. Mohammed
{"title":"Travel & Edible Vaccines","authors":"R. S. Mohammed","doi":"10.33425/2639-8494.1015","DOIUrl":"https://doi.org/10.33425/2639-8494.1015","url":null,"abstract":"However, if we are to maximize their impact on global health, then we need to develop new vaccines for additional disease as well as to improve their supply & delivery, particularly in developing countries. Thus food vaccines might save millions who now die for the lack of access to traditional inoculants. Development of Edible vaccines Creating edible vaccines involves introduction of selected desired gene into plants and then inducing these altered plants to manufacture the encoded proteins. This process is known as transformation & the altered plants are called transgenic plants, like conventional subunit vaccines, edible vaccines are composed of antigenic proteins and are devoid of pathogenic genes. Thus, they have no way of establishing infection, assuring its safety especially in immunocompromised patients.","PeriodicalId":191133,"journal":{"name":"Clinical Immunology & Research","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129263676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Appetite Control and Biotherapy in the Management of Autoimmune Induced Global Chronic Diseases 食欲控制和生物疗法在自身免疫性慢性疾病管理中的应用
Clinical Immunology & Research Pub Date : 2018-05-08 DOI: 10.33425/2639-8494.1014
I. Martins
{"title":"Appetite Control and Biotherapy in the Management of Autoimmune Induced Global Chronic Diseases","authors":"I. Martins","doi":"10.33425/2639-8494.1014","DOIUrl":"https://doi.org/10.33425/2639-8494.1014","url":null,"abstract":"Editorial Appetite control with relevance to immunometabolism has become critical to the treatment of non-alcoholic fatty liver disease (NAFLD), cardiovascular disease and diabetes [1-4]. The major defect in global chronic disease is autoimmune disease with defective adipose tissue and liver interaction involved with the release of inflammatory cytokines and adipocytokines [5] relevant to toxic immune reactions that involve the pancreas brain, heart, thyroid, kidneys and reproductive organs. Appetite control and autoimmune disease are connected with the identification of Sirtuin 1 (Sirt 1) as the anti-aging gene [1-3] involved in appetite regulation and the prevention of autoimmune disease [4].","PeriodicalId":191133,"journal":{"name":"Clinical Immunology & Research","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128347905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
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