食欲控制和生物疗法在自身免疫性慢性疾病管理中的应用

I. Martins
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引用次数: 10

摘要

与免疫代谢相关的食欲控制已成为治疗非酒精性脂肪性肝病(NAFLD)、心血管疾病和糖尿病的关键[1-4]。全球慢性疾病的主要缺陷是脂肪组织缺陷的自身免疫性疾病,肝脏相互作用涉及炎性细胞因子和脂肪细胞因子[5]的释放,与涉及胰腺、脑、心脏、甲状腺、肾脏和生殖器官的毒性免疫反应相关。食欲控制和自身免疫性疾病与Sirtuin 1 (sirt1)作为抗衰老基因被发现有关[1-3],参与食欲调节和自身免疫性疾病[4]的预防。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Appetite Control and Biotherapy in the Management of Autoimmune Induced Global Chronic Diseases
Editorial Appetite control with relevance to immunometabolism has become critical to the treatment of non-alcoholic fatty liver disease (NAFLD), cardiovascular disease and diabetes [1-4]. The major defect in global chronic disease is autoimmune disease with defective adipose tissue and liver interaction involved with the release of inflammatory cytokines and adipocytokines [5] relevant to toxic immune reactions that involve the pancreas brain, heart, thyroid, kidneys and reproductive organs. Appetite control and autoimmune disease are connected with the identification of Sirtuin 1 (Sirt 1) as the anti-aging gene [1-3] involved in appetite regulation and the prevention of autoimmune disease [4].
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