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Neurogastroenterology & Motility最新文献

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The effect of rikkunshito on gastrointestinal symptoms and gastric motor function: The first study in a Belgian functional dyspepsia population 利健茶对胃肠道症状和胃运动功能的影响:比利时功能性消化不良人群的首次研究
Neurogastroenterology & Motility Pub Date : 2020-02-01 DOI: 10.1111/nmo.13739
I. Masuy, F. Carbone, L. Holvoet, A. Vandenberghe, T. Vanuytsel, J. Tack
{"title":"The effect of rikkunshito on gastrointestinal symptoms and gastric motor function: The first study in a Belgian functional dyspepsia population","authors":"I. Masuy, F. Carbone, L. Holvoet, A. Vandenberghe, T. Vanuytsel, J. Tack","doi":"10.1111/nmo.13739","DOIUrl":"https://doi.org/10.1111/nmo.13739","url":null,"abstract":"Rikkunshito, a traditional Kampo medicine, has shown efficacy to treat functional dyspepsia (FD) in controlled trials in Japan. Its putative benefit for European patients and mechanism of action has not been established.","PeriodicalId":19104,"journal":{"name":"Neurogastroenterology & Motility","volume":"57 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91451171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Ghrelin abates bacterial translocation following burn injury by improving gastric emptying 胃饥饿素通过改善胃排空来减少烧伤后细菌的易位
Neurogastroenterology & Motility Pub Date : 2020-02-01 DOI: 10.1111/nmo.13742
H. Sallam, P. Urvil, T. Savidge, Jiande D. Z. Chen
{"title":"Ghrelin abates bacterial translocation following burn injury by improving gastric emptying","authors":"H. Sallam, P. Urvil, T. Savidge, Jiande D. Z. Chen","doi":"10.1111/nmo.13742","DOIUrl":"https://doi.org/10.1111/nmo.13742","url":null,"abstract":"In severe burns, increased intestinal permeability facilitates bacterial translocation, resulting in systemic endotoxemia and multi‐organ failure. We investigated the role of burn‐induced gastrointestinal dysmotility (BIGD) in promoting bacterial translocation following burn injury, and the protective effect of ghrelin in this process.","PeriodicalId":19104,"journal":{"name":"Neurogastroenterology & Motility","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81092948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Normative values for region‐specific colonic and gastrointestinal transit times in 111 healthy volunteers using the 3D‐Transit electromagnet tracking system: Influence of age, gender, and body mass index 111名健康志愿者使用3D - transit电磁体追踪系统测量特定区域结肠和胃肠运输时间的标准值:年龄、性别和体重指数的影响
Neurogastroenterology & Motility Pub Date : 2020-02-01 DOI: 10.1111/nmo.13734
G. Nandhra, E. Mark, G. D. Di Tanna, A. Haase, J. Poulsen, S. Christodoulides, V. Kung, M. Klinge, K. Knudsen, P. Borghammer, Katrine O Andersen, L. Fynne, Nanna Sutter, V. Schlageter, K. Krogh, A. Drewes, M. Birch, S. Scott
{"title":"Normative values for region‐specific colonic and gastrointestinal transit times in 111 healthy volunteers using the 3D‐Transit electromagnet tracking system: Influence of age, gender, and body mass index","authors":"G. Nandhra, E. Mark, G. D. Di Tanna, A. Haase, J. Poulsen, S. Christodoulides, V. Kung, M. Klinge, K. Knudsen, P. Borghammer, Katrine O Andersen, L. Fynne, Nanna Sutter, V. Schlageter, K. Krogh, A. Drewes, M. Birch, S. Scott","doi":"10.1111/nmo.13734","DOIUrl":"https://doi.org/10.1111/nmo.13734","url":null,"abstract":"The 3D‐Transit electromagnet tracking system (Motilis Medica, SA, Lausanne, Switzerland) is an emerging tool for the ambulatory assessment of gastrointestinal (GI) transit and motility. Using this tool, we aimed to derive normative values for region‐specific colonic and GI transit times and to assess the influence of age, gender, and body mass index (BMI).","PeriodicalId":19104,"journal":{"name":"Neurogastroenterology & Motility","volume":"103 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78436263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 38
Endogenous control of inflammatory visceral pain by T cell‐derived opioids in IL‐10‐deficient mice IL - 10缺失小鼠中T细胞源性阿片类药物内源性控制炎性内脏疼痛
Neurogastroenterology & Motility Pub Date : 2020-02-01 DOI: 10.1111/nmo.13743
L. Basso, Mehdi Benamar, Xavier Mas-Orea, C. Deraison, C. Blanpied, N. Cenac, A. Saoudi, G. Dietrich
{"title":"Endogenous control of inflammatory visceral pain by T cell‐derived opioids in IL‐10‐deficient mice","authors":"L. Basso, Mehdi Benamar, Xavier Mas-Orea, C. Deraison, C. Blanpied, N. Cenac, A. Saoudi, G. Dietrich","doi":"10.1111/nmo.13743","DOIUrl":"https://doi.org/10.1111/nmo.13743","url":null,"abstract":"The opioid‐mediated analgesic activity of mucosal CD4+ T lymphocytes in colitis has been reported in immunocompetent mice so far. Here, we investigated whether CD4+ T lymphocytes alleviate from inflammation‐induced abdominal pain in mice with defective immune regulation.","PeriodicalId":19104,"journal":{"name":"Neurogastroenterology & Motility","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73697245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Effects of acotiamide on functional dyspepsia patients with heartburn who failed proton pump inhibitor treatment in Japanese patients: A randomized, double‐blind, placebo‐controlled crossover study 阿可替胺对日本质子泵抑制剂治疗失败的功能性消化不良伴胃灼热患者的影响:一项随机、双盲、安慰剂对照交叉研究
Neurogastroenterology & Motility Pub Date : 2020-02-01 DOI: 10.1111/nmo.13749
Y. Funaki, N. Ogasawara, Yurika Kawamura, T. Yoshimine, Yasuhiro Tamura, S. Izawa, M. Ebi, M. Sasaki, K. Kasugai
{"title":"Effects of acotiamide on functional dyspepsia patients with heartburn who failed proton pump inhibitor treatment in Japanese patients: A randomized, double‐blind, placebo‐controlled crossover study","authors":"Y. Funaki, N. Ogasawara, Yurika Kawamura, T. Yoshimine, Yasuhiro Tamura, S. Izawa, M. Ebi, M. Sasaki, K. Kasugai","doi":"10.1111/nmo.13749","DOIUrl":"https://doi.org/10.1111/nmo.13749","url":null,"abstract":"Functional dyspepsia (FD) and non‐erosive reflux disease (NERD) are gastrointestinal disorders that often overlap. In this randomized, double‐blind, placebo‐controlled crossover study, the effects of adding acotiamide to treatment with proton pump inhibitors (PPI) were investigated in FD patients with heartburn who failed PPI treatment, corresponding to PPI‐resistant NERD.","PeriodicalId":19104,"journal":{"name":"Neurogastroenterology & Motility","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84375880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Utility of the plasma pancreatic polypeptide response to modified sham feeding in diabetic gastroenteropathy and non‐ulcer dyspepsia 血浆胰多肽对改良假喂养在糖尿病性胃肠病和非溃疡性消化不良中的作用
Neurogastroenterology & Motility Pub Date : 2020-02-01 DOI: 10.1111/nmo.13744
Anshuman C. Desai, P. Low, M. Camilleri, W. Singer, D. Burton, S. Chakraborty, A. Bharucha
{"title":"Utility of the plasma pancreatic polypeptide response to modified sham feeding in diabetic gastroenteropathy and non‐ulcer dyspepsia","authors":"Anshuman C. Desai, P. Low, M. Camilleri, W. Singer, D. Burton, S. Chakraborty, A. Bharucha","doi":"10.1111/nmo.13744","DOIUrl":"https://doi.org/10.1111/nmo.13744","url":null,"abstract":"The relationship between cardiovascular and gastrointestinal (ie, plasma pancreatic polypeptide [PP] response to modified sham feeding [MSF]) indices of vagal function is unclear. Hyperglycemia inhibits PP secretion via vagally mediated mechanisms. Our aims were to (a) compare the PP response, (b) its relationship with glycemia, and (c) the relationship between PP response to MSF, gastric emptying (GE) of solids, and symptoms during GE study in healthy controls, patients with diabetic gastroenteropathy (DM), and non‐ulcer dyspepsia (NUD).","PeriodicalId":19104,"journal":{"name":"Neurogastroenterology & Motility","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80018844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Codeine delays gastric emptying through inhibition of gastric motility as assessed with a novel diagnostic intragastric balloon catheter 可待因通过抑制胃运动延缓胃排空，以一种新的诊断性胃内球囊导管评估
Neurogastroenterology & Motility Pub Date : 2020-01-01 DOI: 10.1111/nmo.13733
N. Goelen, J. D. de Hoon, John F. Morales, C. Varon, S. Van Huffel, P. Augustijns, R. Mols, Marissa Herbots, K. Verbeke, T. Vanuytsel, J. Tack, P. Janssen
{"title":"Codeine delays gastric emptying through inhibition of gastric motility as assessed with a novel diagnostic intragastric balloon catheter","authors":"N. Goelen, J. D. de Hoon, John F. Morales, C. Varon, S. Van Huffel, P. Augustijns, R. Mols, Marissa Herbots, K. Verbeke, T. Vanuytsel, J. Tack, P. Janssen","doi":"10.1111/nmo.13733","DOIUrl":"https://doi.org/10.1111/nmo.13733","url":null,"abstract":"The use of opioids as analgesic is on the rise, despite their inhibitory effect on gastric emptying. A novel feeding catheter with integrated intragastric balloon was developed to continuously assess gastric motility, enabling to investigate the effect of opioids on motility and emptying simultaneously. We aimed to discriminate normal and pharmacologically impaired gastric motility and its impact on gastric emptying in healthy adults.","PeriodicalId":19104,"journal":{"name":"Neurogastroenterology & Motility","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79136514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Exacerbation of gastroesophageal reflux symptoms after discontinuation of proton pump inhibitors is not associated with increased esophageal acid exposure 停止质子泵抑制剂后胃食管反流症状的加重与食管酸暴露增加无关
Neurogastroenterology & Motility Pub Date : 2020-01-01 DOI: 10.1111/nmo.13735
Yoshimasa Hoshikawa, K. Nikaki, S. Sonmez, K. Nakagawa, E. Yazaki, D. Sifrim, P. Woodland
{"title":"Exacerbation of gastroesophageal reflux symptoms after discontinuation of proton pump inhibitors is not associated with increased esophageal acid exposure","authors":"Yoshimasa Hoshikawa, K. Nikaki, S. Sonmez, K. Nakagawa, E. Yazaki, D. Sifrim, P. Woodland","doi":"10.1111/nmo.13735","DOIUrl":"https://doi.org/10.1111/nmo.13735","url":null,"abstract":"Discontinuation of long‐term proton pump inhibitors (PPIs) on patients with reflux symptoms can be challenging, as symptoms often exacerbate after stopping. The mechanism remains unknown. Our aim was to evaluate the impact of stopping long‐term PPIs on patients with heartburn, and its association with esophageal acid exposure.","PeriodicalId":19104,"journal":{"name":"Neurogastroenterology & Motility","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82456244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Acute administration of fructans increases the number of transient lower esophageal sphincter relaxations in healthy volunteers 急性服用果聚糖可增加健康志愿者短暂性下食道括约肌松弛的次数
Neurogastroenterology & Motility Pub Date : 2020-01-01 DOI: 10.1111/nmo.13727
H. Geysen, E. Gielis, E. Deloose, T. Vanuytsel, J. Tack, J. Biesiekierski, A. Pauwels
{"title":"Acute administration of fructans increases the number of transient lower esophageal sphincter relaxations in healthy volunteers","authors":"H. Geysen, E. Gielis, E. Deloose, T. Vanuytsel, J. Tack, J. Biesiekierski, A. Pauwels","doi":"10.1111/nmo.13727","DOIUrl":"https://doi.org/10.1111/nmo.13727","url":null,"abstract":"Dietary measures are often advised to patients with gastro‐esophageal reflux disease (GERD). Fermentable Oligo‐, Di‐, Mono‐saccharides and Polyols (FODMAPs) induce lower gastrointestinal (GI) symptoms. However, their effects on esophageal motility, including transient lower esophageal sphincter relaxations (TLESRs), reflux events and GERD symptoms are unknown. We investigated the effect of acute administration of two FODMAPs, fructose, and fructans, on the number of TLESRs, reflux episodes and symptom perception in healthy volunteers (HVs).","PeriodicalId":19104,"journal":{"name":"Neurogastroenterology & Motility","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74928733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Chaotic peak propagation in patients with Jackhammer esophagus 风钻式食管患者的混沌峰值传播
Neurogastroenterology & Motility Pub Date : 2020-01-01 DOI: 10.1111/nmo.13725
Yinglian Xiao, D. Carlson, Zhiyue Lin, J. Pandolfino
{"title":"Chaotic peak propagation in patients with Jackhammer esophagus","authors":"Yinglian Xiao, D. Carlson, Zhiyue Lin, J. Pandolfino","doi":"10.1111/nmo.13725","DOIUrl":"https://doi.org/10.1111/nmo.13725","url":null,"abstract":"The contractile activity of Jackhammer esophagus(JE) is heterogeneous and abnormalities in the balance of pre‐ and post‐peak contractile activity has been reported. We observed that the progression of the peak contraction is disordered in JE patients, which reflect underlying abnormalities in the inhibitory and excitatory influence in esophageal contraction. In order to better define this abnormality, we developed novel time metrics to define trajectory of the pressure wave peak and assessed it in healthy controls and JE patients.","PeriodicalId":19104,"journal":{"name":"Neurogastroenterology & Motility","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75984374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
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