可待因通过抑制胃运动延缓胃排空,以一种新的诊断性胃内球囊导管评估

N. Goelen, J. D. de Hoon, John F. Morales, C. Varon, S. Van Huffel, P. Augustijns, R. Mols, Marissa Herbots, K. Verbeke, T. Vanuytsel, J. Tack, P. Janssen
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引用次数: 14

摘要

阿片类药物作为镇痛药的使用呈上升趋势,尽管它们对胃排空有抑制作用。本研究设计了一种新型胃内球囊灌胃导管,用于持续评估胃运动,从而研究阿片类药物对胃运动和排空的影响。我们的目的是区分正常和药物损害的胃运动及其对健康成人胃排空的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Codeine delays gastric emptying through inhibition of gastric motility as assessed with a novel diagnostic intragastric balloon catheter
The use of opioids as analgesic is on the rise, despite their inhibitory effect on gastric emptying. A novel feeding catheter with integrated intragastric balloon was developed to continuously assess gastric motility, enabling to investigate the effect of opioids on motility and emptying simultaneously. We aimed to discriminate normal and pharmacologically impaired gastric motility and its impact on gastric emptying in healthy adults.
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