阿可替胺对日本质子泵抑制剂治疗失败的功能性消化不良伴胃灼热患者的影响:一项随机、双盲、安慰剂对照交叉研究

Neurogastroenterology & Motility Pub Date : 2020-02-01 DOI:10.1111/nmo.13749

Y. Funaki, N. Ogasawara, Yurika Kawamura, T. Yoshimine, Yasuhiro Tamura, S. Izawa, M. Ebi, M. Sasaki, K. Kasugai

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引用次数: 5

摘要

功能性消化不良(FD)和非糜烂性反流病(NERD)是经常重叠的胃肠道疾病。在这项随机、双盲、安慰剂对照的交叉研究中，研究了在质子泵抑制剂(PPI)治疗失败的FD胃灼热患者(对应于PPI耐药的NERD)中添加阿柯替胺的效果。

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Effects of acotiamide on functional dyspepsia patients with heartburn who failed proton pump inhibitor treatment in Japanese patients: A randomized, double‐blind, placebo‐controlled crossover study

Functional dyspepsia (FD) and non‐erosive reflux disease (NERD) are gastrointestinal disorders that often overlap. In this randomized, double‐blind, placebo‐controlled crossover study, the effects of adding acotiamide to treatment with proton pump inhibitors (PPI) were investigated in FD patients with heartburn who failed PPI treatment, corresponding to PPI‐resistant NERD.

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Neurogastroenterology & Motility

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