Nature Reviews Urology最新文献_第10页

Renal mass biopsy — a practical and clinicopathologically relevant approach to diagnosis 肾肿块活检--一种实用且与临床病理相关的诊断方法。

IF 12.1 1区医学

Nature Reviews Urology Pub Date : 2024-06-21 DOI: 10.1038/s41585-024-00897-5

Hussein Mansour, My-Anh Tran-Dang, Miles Walkden, Ekaterini Boleti, Ravi Barod, Prasad Patki, Faiz Mumtaz, Maxine G. B. Tran, Axel Bex, Soha El Sheikh

{"title":"Renal mass biopsy — a practical and clinicopathologically relevant approach to diagnosis","authors":"Hussein Mansour, My-Anh Tran-Dang, Miles Walkden, Ekaterini Boleti, Ravi Barod, Prasad Patki, Faiz Mumtaz, Maxine G. B. Tran, Axel Bex, Soha El Sheikh","doi":"10.1038/s41585-024-00897-5","DOIUrl":"10.1038/s41585-024-00897-5","url":null,"abstract":"Advancements in imaging modalities have increased the frequency of renal mass discovery. Imaging has typically been considered sufficient to guide management for a large proportion of these tumours, but renal mass biopsies (RMBs) have an increasing role in determining malignancy and can be a valuable tool for preventing unnecessary surgery in patients with benign tumours. A structured approach should be used to help to navigate the expanding repertoire of renal tumours, many of which are molecularly defined. In terms of tumour subtyping, the pathologist’s strategy should focus on stratifying patients into clinically different prognostic groups according to our current knowledge of tumour behaviour, including benign, low-grade or indolent, intermediate malignant or highly aggressive. Crucial pathological features and morphological mimicry of tumours can alter the tumour’s prognostic group. Thus, pathologists and urologists can use RMB to select patients with tumours at a reduced risk of progression, which can be safely managed with active surveillance within a tailored imaging schedule, versus tumours for which ablation or surgical intervention is indicated. RMB is also crucial in the oncological setting to distinguish between different high-grade tumours and guide tailored management strategies. In this Review, the authors discuss advantages and complications associated with renal mass biopsy and provide an overview of different features of both well-recognized types of renal cell carcinoma and newly identified subtypes to improve diagnosis and management.","PeriodicalId":19088,"journal":{"name":"Nature Reviews Urology","volume":"22 1","pages":"8-25"},"PeriodicalIF":12.1,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141437223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The bladder tumour microbiome and BCG response 膀胱肿瘤微生物群与卡介苗反应

IF 12.1 1区医学

Nature Reviews Urology Pub Date : 2024-06-18 DOI: 10.1038/s41585-024-00910-x

Louise Lloyd

引用次数: 0

Progression-free survival end points in prostate cancer: are we truly making progress 前列腺癌无进展生存期终点：我们是否真正取得了进展

IF 12.1 1区医学

Nature Reviews Urology Pub Date : 2024-06-17 DOI: 10.1038/s41585-024-00902-x

Ravi A. Madan, Edwin M. Posadas, Richard J. Lee

引用次数: 0

Single-cell penile cancer atlas to identify disease drivers 单细胞阴茎癌图谱确定疾病驱动因素

IF 12.1 1区医学

Nature Reviews Urology Pub Date : 2024-06-14 DOI: 10.1038/s41585-024-00909-4

Maria Chiara Masone

引用次数: 0

Promising efficacy of UTI vaccines as an alternative to antibiotics 尿毒症疫苗替代抗生素的疗效令人期待

IF 12.1 1区医学

Nature Reviews Urology Pub Date : 2024-06-14 DOI: 10.1038/s41585-024-00905-8

Quentin Mak, Julian Greig, Prokar Dasgupta, Sachin Malde, Nicholas Raison

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A new signalling-based system for germ cell reprogramming 基于信号的生殖细胞重编程新系统

IF 12.1 1区医学

Nature Reviews Urology Pub Date : 2024-06-13 DOI: 10.1038/s41585-024-00907-6

Maria Chiara Masone

引用次数: 0

A prompt-based stewardship to reduce extended-spectrum antibiotic treatment in UTI 减少尿毒症扩展谱抗生素治疗的及时监管。

IF 12.1 1区医学

Nature Reviews Urology Pub Date : 2024-06-13 DOI: 10.1038/s41585-024-00908-5

Maria Chiara Masone

引用次数: 0

Engaging medical students in urological academic research 让医科学生参与泌尿外科学术研究。

IF 12.1 1区医学

Nature Reviews Urology Pub Date : 2024-06-11 DOI: 10.1038/s41585-024-00903-w

Kamil Malshy, Taylor Braunagel, Anna Ochsner, Borivoj Golijanin, Elias Hyams

引用次数: 0

Rediscovering citrate as a biomarker for prostate cancer 重新发现作为前列腺癌生物标志物的柠檬酸盐。

IF 12.1 1区医学

Nature Reviews Urology Pub Date : 2024-05-29 DOI: 10.1038/s41585-024-00899-3

Lucas Galey, Ayokunle Olanrewaju, Hermann Nabi, Jean-Sébastien Paquette, Frédéric Pouliot, Étienne Audet-Walsh

引用次数: 0

Nocturia and obstructive sleep apnoea 夜尿和阻塞性睡眠呼吸暂停。

IF 12.1 1区医学

Nature Reviews Urology Pub Date : 2024-05-23 DOI: 10.1038/s41585-024-00887-7

Olaf P. J. Vrooman, Philip E. V. van Kerrebroeck, Michael R. van Balken, Gommert A. van Koeveringe, Mohammad S. Rahnama’i

{"title":"Nocturia and obstructive sleep apnoea","authors":"Olaf P. J. Vrooman, Philip E. V. van Kerrebroeck, Michael R. van Balken, Gommert A. van Koeveringe, Mohammad S. Rahnama’i","doi":"10.1038/s41585-024-00887-7","DOIUrl":"10.1038/s41585-024-00887-7","url":null,"abstract":"Nocturia, the need to urinate at night, is a common symptom in patients with obstructive sleep apnoea (OSA). Continuous positive airway pressure treatment can reduce nocturia in some patients, but the underlying mechanisms are complex and not fully understood. OSA affects the autonomic nervous system, oxidative stress and endothelial damage. Furthermore, the commonly held theory attributing polyuria to a false signal of cardiac overload and response natriuresis has limitations. A comprehensive approach to the management of nocturia in OSA, considering factors such as comorbidities, medication use, alcohol consumption and lifestyle, is needed. Effective management of nocturia in OSA requires a multidisciplinary approach, and urologists should be aware of the potential effect of OSA on physiology and refer patients for further testing at a sleep centre. In addition to continuous positive airway pressure, other interventions such as oral appliances and surgical obstruction treatment could be beneficial for some patients. Overall, understanding the complex interplay between OSA and nocturia is crucial for optimizing patient outcomes. In this Review, the authors provide urologists and other interested physicians with an improved understanding of the multifactorial pathophysiology underlying the correlation between obstructive sleep apnoea and nocturia. They describe current evidence, identify topics for future research, and provide practical recommendations for managing patients with this complex condition.","PeriodicalId":19088,"journal":{"name":"Nature Reviews Urology","volume":"21 12","pages":"735-753"},"PeriodicalIF":12.1,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141087771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0