Paediatric respiratory epidemiology最新文献_第6页

Viral etiologies in childhood wheezing illness, asthma and respiratory infections 儿童喘息疾病、哮喘和呼吸道感染的病毒病因

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa298

G. Wong, Yuhan Xing, E. Yung, T. Leung

引用次数: 0

Vitamin D status during pregnancy and wheezing and asthma during childhood 怀孕期间的维生素D状况，儿童时期的喘息和哮喘

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa308

Júlia Sangüesa, M. Bustamante, A. Abellan, M. Basterrechea, Ana Esplugues, J. Garcia-Aymerich, M. Guxens, J. Júlvez, A. Irizar, C. Roda, Ana Cristina Rodríguez-Delhi, J. Vioque, M. Vrijheid, A. Tardón, M. Torrent, J. Sunyer, M. Casas

引用次数: 0

Evaluation of psychogenic respiratory behaviours in children 儿童心因性呼吸行为的评价

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa1047

H. Yazan, A. Orengul, E. Ertaş, E. Çakır

{"title":"Evaluation of psychogenic respiratory behaviours in children","authors":"H. Yazan, A. Orengul, E. Ertaş, E. Çakır","doi":"10.1183/13993003.congress-2019.pa1047","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa1047","url":null,"abstract":"Introduction: Psychogenic respiratory behaviours (PRB) such as psychogenic cough (tic cough), barking, sighing, feeling of shortness of breath, and throat clearing tic are common in adolescent children. The aim of this study was to compare the sociodemographic and clinical characteristics of the patients with psychogenic respiratory behaviour to the control group and to evaluate their diagnosis according to DSM-5. Method: The study includes 52 children with PRB and control group, which includes 42 children, without any chronic disease. Patients who were followed-up in our Pediatric Pulmonology outpatient clinic between January 2017 and November 2018 were included in the study. Results: The mean age of the patients with PRB was 11.25 ± 2.61, it was 11.17 ± 2.58 in the control group. There were cough in 35 patients, shortness of breath, in 11 patients throat clearance in 11 patients and deep sighing in 6 patients. Symptoms were more than 6 months in most patients. Considering the previous examinations; PA-AC radiography 84.6%, allergy skin tests 76.9%, blood test 82.7%, spirometry 73.1% and CT 23.1% were performed in patients . Least one psychiatric disease was detected at 55.8% of PRB group and this rate was 28.6% in the control group. Discussion and Conclusion: Psychogenic respiratory problems are usually diagnosed by exclusion of other diseases. This diagnosis should be considered in the adolescent age group which has no pathology in physical examination but especially high stress factor. In suspected patients, early psychiatric evaluation is important for early diagnosis of these patients.","PeriodicalId":190855,"journal":{"name":"Paediatric respiratory epidemiology","volume":"144 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116421836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Allergic rhinitis co-morbidity as risk factor on lung function parameters recovery after asthma exacerbation 变应性鼻炎作为哮喘加重后肺功能参数恢复的危险因素

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa1048

V. Veković, Z. Zivković, B. Vekovic, M. Tomašević

{"title":"Allergic rhinitis co-morbidity as risk factor on lung function parameters recovery after asthma exacerbation","authors":"V. Veković, Z. Zivković, B. Vekovic, M. Tomašević","doi":"10.1183/13993003.congress-2019.pa1048","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa1048","url":null,"abstract":"Asthma and rhinitis are the most common chronic health issues in children today. They come together in vast majority of cases, supporting idea that both are part of the broader spectrum of respiratory allergic disorders. Influence is bi-directional and treatment and management should consider both disease simultaneously. Aim of this prospective study is to show, weather presence of rhinitis as co-morbidity, is significant risk factor for prolonged recovery of lung function parameters after asthma flare ups. Our study included 60 children divided into two groups. First group of 30 children with asthma and rhinitis(A+AR). And second group with 30 children with asthma and no rhinitis(A). Both groups performed pulmonary lung function tests in days 7th,14th,21st, following asthma flare up. In the first group (A+AR) parameters FEV1, FVC and FEF25-75% showed more sever flare up. In the first group (A+AR) at the end of first week, parameters FEV1, FVC and FEF25-75%, showed statistically significant lower values- FEV1(p=0.050), FVC(p=0,026), FEF25-75%(p=0,050). Through following weeks there was statistical difference in values of FEV1, lower in first group (A+AR) and with slower recovery. There was no difference in values of FEF25-75% parameter between these groups. In conclusion, pulmonary lung function values were more decreased, FEV1 showed slower recovery and flare ups were more severe in group with associated rhinitis.","PeriodicalId":190855,"journal":{"name":"Paediatric respiratory epidemiology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131638199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pneumomediastinum in children: a rare entity? 儿童纵隔气肿:一种罕见的疾病?

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa1039

Natália Neto Dias, Bárbara Neffa, S. Sias

{"title":"Pneumomediastinum in children: a rare entity?","authors":"Natália Neto Dias, Bárbara Neffa, S. Sias","doi":"10.1183/13993003.congress-2019.pa1039","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa1039","url":null,"abstract":"Pneumomediastinum corresponds to the presence of free air in the mediastinum, which may be spontaneous or secondary (trauma, mechanical ventilation, etc.). Described as rare in the child, his diagnosis is underestimated. It manifests with dyspnoea, cough and chest pain, and occasionally subcutaneous emphysema. The objective is to report the radiological clinical profile of five cases of pneumomediastinum. Five cases were diagnosed, 4 boys and 1 girl, with a mean age of 3.7 years (range = 3 months to 5 years). In two, there was a previous history of controlled asthma, one had a chronic cough, with no previous diagnosis of asthma, one with acute viral bronchiolitis and another with non-progressive chronic encephalopathy with noninvasive ventilation. All were admitted to the emergency room and 4 needed an intensive care unit. Symptomatology included cough (n = 5), dyspnea (n = 5), oxygen desaturation (3), subcutaneous emphysema (4) and chest pain (n = 2). All presented radiological alterations suggestive of pneumomediastinum, confirmed by HRCT in 4. There was complete recovery in 4 cases, without relapse until this moment. One case evolved to death. Conclusion: The diagnosis of pneumomediastinum in pediatrics requires a high index of suspicion, careful clinical evaluation and should be considered in children with acute chest pain. The clinical diagnosis is complemented by chest X-ray. It presents frequently benign evolution, being rare the relapse. The increasing description in the literature, especially of spontaneous cases (Hammam Syndrome) suggests that this condition was being underdiagnosed.","PeriodicalId":190855,"journal":{"name":"Paediatric respiratory epidemiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126290474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tobacco exposure in utero and childhood asthma and wheeze – a register-based cohort study 子宫内烟草暴露与儿童哮喘和喘息——一项基于登记的队列研究

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.oa4968

C. Lundholm, Anna Gunnerbeck, B. D’Onofrio, H. Larsson, G. Pershagen, C. Almqvist

引用次数: 1

Children with history of bronchopulmonary dysplasia have low fitness capacity at school age 有支气管肺发育不良史的儿童学龄健身能力较低

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa295

M. Praprotnik, I. S. Gantar, G. Starc, U. Krivec

引用次数: 0

Less sun, more cough: Annual hours of sunshine are inversely associated with hospital admissions for children with lower respiratory tract infection 日照少，咳嗽多:每年日照时间与下呼吸道感染儿童住院率成反比

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.oa4970

James J. Walker, F. Gilchrist, W. Carroll

{"title":"Less sun, more cough: Annual hours of sunshine are inversely associated with hospital admissions for children with lower respiratory tract infection","authors":"James J. Walker, F. Gilchrist, W. Carroll","doi":"10.1183/13993003.congress-2019.oa4970","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.oa4970","url":null,"abstract":"Background: Vitamin D deficiency affects immune function increasing susceptibility to respiratory tract infections (RTI). Randomised controlled trials show vitamin D supplementation protects against acute RTIs. Most vitamin D (>90%) is acquired from sun exposure. Objective: To determine whether there is an association between hours of sunshine, deprivation status and severe lower respiratory tract infection rates (LRTI) in English children. Methods: The annualised age-gender corrected severe LRTI (agc-LRTI) rate for children Results: During the study period 314,226 children were admitted to English hospitals with LRTI. The child population varied between 9,654,027 and 9,853,580. The mean agc-LRTI rate was 357/100,000. The annual HoS in each region varied between 1287 hours (NW 2008-9) and 1815 hours (SE & Central 2006-7). There was a strong inverse association between HoS and agc-LRTI admission rates in English regions (p Conclusion: Long-term weather patterns are associated with admissions to hospital for children with LRTI. Sunnier regions and sunnier years have lower LRTI admission rates when correcting for age, gender and deprivation. It is biologically plausible that this effect is mediated by vitamin D.","PeriodicalId":190855,"journal":{"name":"Paediatric respiratory epidemiology","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126503733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Wheeze attacks during the first 3 years of life following an episode of hospitalized bronchiolitis – is there a viral association? 住院的毛细支气管炎发作后3年内的喘息发作-是否与病毒有关?

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa304

Heidi Makrinioti, Vivian Maggina, P. Xepapadaki, S. Taka, S. Johnston, M. Tsolia, V. Papaevangelou, N. Papadopoulos

{"title":"Wheeze attacks during the first 3 years of life following an episode of hospitalized bronchiolitis – is there a viral association?","authors":"Heidi Makrinioti, Vivian Maggina, P. Xepapadaki, S. Taka, S. Johnston, M. Tsolia, V. Papaevangelou, N. Papadopoulos","doi":"10.1183/13993003.congress-2019.pa304","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa304","url":null,"abstract":"Introduction: Acute bronchiolitis is the most frequent respiratory infection in the beginning of life and has been associated with an increasing number of hospital admissions. Respiratory syncytial virus (RSV) has been considered as the most common cause of bronchiolitis. However, other viruses, such as rhinovirus (RV), have also been associated with increased clinical severity as well as with wheeze sequelae. Currently there is no consensus as to whether a specific virus detected during the first episode of hospitalized bronchiolitis could link to the incidence of recurrent wheeze. This is a cohort study of term infants that aims to add to the field. Methods: This is a prospective cohort study including 131 otherwise healthy term infants presenting with the first episode of hospitalized bronchiolitis and 73 age-matched control patients. A panel of 8 respiratory viruses were detected in nasopharyngeal washes. All patients were followed up until the age of 3 years old by with 6 monthly telephone reviews. Measured outcomes were the incidence of wheeze attacks, the number of reported admissions with wheeze and total number of treatment days. Results: Infants hospitalized with RV-induced bronchiolitis had a higher clinical severity score and exhibited statistically higher number of wheeze attacks, associated hospital admissions and associated treatment during the first 3 years of life (p Conclusion: In a cohort of term infants requiring admission with bronchiolitis, the level of severity of bronchiolitis episode and the incidence and persistence of wheeze during the first years of life were most strongly associated with RV detection.","PeriodicalId":190855,"journal":{"name":"Paediatric respiratory epidemiology","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124304513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early infancy BMI trajectories and lung function and asthma during childhood 婴儿早期BMI轨迹与肺功能和儿童哮喘的关系

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.oa4966

G. Peralta, P. Montazeri, A. Abellan, M. Basterrechea, Ana Espluges, Sandra Gonzalez, C. Roda, L. S. Marina, M. Vrijheid, M. Casas, J. Garcia-Aymerich

{"title":"Early infancy BMI trajectories and lung function and asthma during childhood","authors":"G. Peralta, P. Montazeri, A. Abellan, M. Basterrechea, Ana Espluges, Sandra Gonzalez, C. Roda, L. S. Marina, M. Vrijheid, M. Casas, J. Garcia-Aymerich","doi":"10.1183/13993003.congress-2019.oa4966","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.oa4966","url":null,"abstract":"Previous studies assessing the association of birthweight and infant weight gain with lung function and asthma have focused on the difference between two time points or on growth patterns. Body mass index (BMI) trajectories, which integrate information on multiple aspects of growth, may allow a more accurate identification of children at higher risk of future respiratory diseases. We assessed the associations of BMI trajectories from birth to 4 years with lung function and current asthma at 7 years. We included 1399 participants from the population-based INMA birth cohort study. Five BMI trajectories were previously identified: ‘average birth size-slower BMI gain’, ‘higher birth size-accelerated BMI gain’, ‘higher birth size-slower BMI gain’, ‘lower birth size-accelerated BMI gain’ and ‘lower birth size-slower BMI gain’. At 7 years, lung function (FVC, FEV1, FEV1/FVC) was assessed by spirometry and current asthma was assessed by questionnaire. After adjustment for potential confounders, children in the accelerated BMI gain trajectories had higher FVC at 7 years either if they departed from lower (37mL; 95%CI: -1.2 to 75) or higher (51mL; 13 to 90) birth size, compared to children in the ‘average birth size-slower BMI gain’ trajectory. These two groups also presented lower FEV1/FVC at 7 years, although the associations were not statistically significant. Children in the ‘low birth size-slower BMI gain’ trajectory had -47mL (95%CI: -84 to -11) lower FVC at 7 years, compared to children in the ‘average birth size-slower BMI gain’ trajectory. No associations were observed for FEV1 or asthma. Early infancy BMI trajectories can identify adverse growth patterns associated with future poorer respiratory health.","PeriodicalId":190855,"journal":{"name":"Paediatric respiratory epidemiology","volume":"174 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133383991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2