Paediatric respiratory epidemiology最新文献_第4页

Effect of pneumococcal conjugate vaccination on radiological findings of chest in infants hospitalized with community acquired pneumonia in northern India: a case-control study 肺炎球菌结合疫苗接种对印度北部社区获得性肺炎住院婴儿胸部放射学表现的影响:一项病例对照研究

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa1036

S. Awasthi, C. Pandey, N. Verma, C. Kumar, C. Roy, K. Mishra, P. Jain, Rajesh B. Yadav, R. Shukla, N. Mohindra, A. Chauhan, M. Agarwal, N. Kohli

{"title":"Effect of pneumococcal conjugate vaccination on radiological findings of chest in infants hospitalized with community acquired pneumonia in northern India: a case-control study","authors":"S. Awasthi, C. Pandey, N. Verma, C. Kumar, C. Roy, K. Mishra, P. Jain, Rajesh B. Yadav, R. Shukla, N. Mohindra, A. Chauhan, M. Agarwal, N. Kohli","doi":"10.1183/13993003.congress-2019.pa1036","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa1036","url":null,"abstract":"Background: Burden of community acquired pneumonia (CAP) in infants is high in India. Streptococcus pneumoniae is stated to be an common etiological agent for it. Hence Pneumococcal Conjugate Vaccination(PCV) has been introduced in India since 2017(phased-wise). Objective: To study effect of PCV on radiological findings of chest in infants hospitalized with WHO-defined CAP. Methods: Prospective hospital-based pneumonia surveillance is ongoing since 2015 in Lucknow & Etawah districts, Uttar Pradesh and Patna & Darbhanga districts, Bihar, India. Recruitments were done from a network of hospitals formed for project. Infants(2-11months)hospitalized with WHO-defined CAP from index districts with Results: From May2017-October2018, 282(22.7%females) infants with PCV vaccination (cases) and 570 (29.8%females) without PCV vaccination (controls) with interpretable CXRs were analyzed. Primary end point pneumonia (PEP)+other infiltrate (OI) were found in 43(15.2%) cases and 140 (24.7%)controls (p=0.001);OI in 30(10.6%) cases and 69(12.1%) controls (p =0.5) and normal CXR in 209 (74.1%) cases and 361(63.3%) controls (p=0.001). There was one death among cases whose CXR showed OI. There were 22 deaths among controls whose CXRs showed PEP + OI in 12(54.6%); OI in3(13.6%) and normal7(31.8%). Crude odds ratio for death among cases was 0.088 (95 %: CI 0.012-0.66). Conclusion: Among hospitalized patients of CAP, radiological findings differ by PCV vaccination status in infants.","PeriodicalId":190855,"journal":{"name":"Paediatric respiratory epidemiology","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115745461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Asthma and all-cause mortality in children and young adults - a Swedish population based study 儿童和年轻人的哮喘和全因死亡率——瑞典一项基于人群的研究

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.oa4972

E. C. Osvald, H. Bower, C. Lundholm, H. Larsson, Bronwyn K Brew, C. Almqvist

引用次数: 1

Knowing asthma in adolescentes from Uruguaiana: The Global Asthma Network (GAN) 了解乌拉圭青少年哮喘:全球哮喘网络(GAN)

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa300

M. Urrutia-Pereira, H. C. Neto, Pietro Rinelli, L. Simon, P. Ellwood, L. Garcia-Marco, D. Solé

引用次数: 0

Diagnosing children with exercise induced respiratory symptoms – the Swiss Paediatric Airway Cohort 诊断儿童与运动引起的呼吸道症状-瑞士儿科气道队列

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa311

E. Pedersen, C. D. Jong, C. Ardura-Garcia, J. Barben, C. Casaulta, A. Jochmann, P. Latzin, A. Moeller, Dominik Mueller-Suter, N. Regamey, F. Singer, M. Goutaki, C. Kuehni

引用次数: 0

No signs of early lung function decline in a population-based cohort born extremely preterm in the 1980s 在20世纪80年代出生的极度早产人群中，没有早期肺功能下降的迹象

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa294

T. Bårdsen, H. Clemm, M. Benestad, O. Røksund, T. Halvorsen, M. Vollsæter

引用次数: 0

Taking care of parents: Trends in referrals for specialist psychological support for children accessing the long-term ventilation service at Leicester Children’s Hospital and their families 照顾父母:在莱斯特儿童医院获得长期通气服务的儿童及其家人获得专家心理支持的转诊趋势

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa1044

V. Elliott, K. Jain

{"title":"Taking care of parents: Trends in referrals for specialist psychological support for children accessing the long-term ventilation service at Leicester Children’s Hospital and their families","authors":"V. Elliott, K. Jain","doi":"10.1183/13993003.congress-2019.pa1044","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa1044","url":null,"abstract":"The Leicester Children’s Hospital offers specialist care to approximately 80 patients requiring long-term ventilation (LTV). In November 2015, funding was secured for a Specialist Clinical Psychologist to join the team as the first to hold a dedicated post with this population in the UK. In the first year, 12 referrals were made to Psychology representing approximately 15% of the patient population. In year two, a further 6 families were referred, followed by 7 more in year three. Projected data for year four suggests a further 12 families will be referred for psychological support. Referral numbers by end of year four will reach approximately 46% of the total patient population. In year two, 100% of referrals were for parents presenting with clinical levels of anxiety, distress and low mood associated with their child’s medical condition, predominantly those whose children required tracheostomy-ventilation. Current data indicates a trend for increasing numbers of fathers requiring support with managing feelings associated with having a child on LTV. Themes seem to include feelings of responsibility and guilt, managing shifts in perceived paternal role, and high anxiety relating to performing care tasks. Future service delivery will need to be shaped to account for differences in psychological needs between family members. Specific psychological interventions aimed at fathers can be piloted alongside other, family-based interventions. More research is needed into the long-term psychological impact of having a child requiring LTV on all parts of the family system and at different points in the journey.","PeriodicalId":190855,"journal":{"name":"Paediatric respiratory epidemiology","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127906486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modification of effect between air pollution and lung function by the inflammatory potential of diet: a cross sectional study in children 饮食的炎症潜力对空气污染和肺功能之间影响的改变:一项儿童横断面研究

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa1045

F. Mendes, I. Paciência, J. Rufo, M. Farraia, Diana Silva, Pedro Cunha, L. Delgado, A. Moreira, P. Moreira

{"title":"Modification of effect between air pollution and lung function by the inflammatory potential of diet: a cross sectional study in children","authors":"F. Mendes, I. Paciência, J. Rufo, M. Farraia, Diana Silva, Pedro Cunha, L. Delgado, A. Moreira, P. Moreira","doi":"10.1183/13993003.congress-2019.pa1045","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa1045","url":null,"abstract":"Fine particulate matter (PM) can cause systematic inflammation and oxidative stress, which can worsen asthma development and progression. Intake of fatty acids and antioxidants may attenuate some effects of PM but the role of overall dietary intake has not been studied. We aimed to investigate the modification of the association between air pollution and childhood asthma by the dietary inflammatory potential effect. In a cross-sectional study, 501 (48.1% males, aged 7 to 12 years) of 858 children attending 71 classrooms from 20 schools were selected. Spirometry and airway reversibility, exhaled nitric oxide, skin-prick testing and current symptoms (breathing difficulties and irritative cough) were assessed. Dietary inflammatory potential was evaluated by the Dietary Inflammatory Index (DII) and calculated from a 24-hour dietary recall. Indoor air quality measurements were conducted in classrooms for one week. The proportion of effects explained by the exposures to PM2.5 and PM10 were measured by generalized linear mixed model. After adjustments, an inflammatory diet increased the risk of asthma for PM2.5 (OR=1.67, 95% CI 1.03, 2.73) and PM10 (OR= 1.75, 95% CI 1.07, 2.87) levels. Considering the dietary inflammatory potential in PM2.5 and PM10 exposure, the risk of asthma increased in parallel with the DII, being significant for children with asthma (OR= 0.89, 95% CI 0.81, 0.97 and OR= 0.92, 95% CI 0.87, 0.97). These findings provide further support to the role of diet’s inflammatory characteristics modulating the effects of indoor air pollution, highlighting the importance of children’s diet as a potential solution to reduce the asthma risk.","PeriodicalId":190855,"journal":{"name":"Paediatric respiratory epidemiology","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127487121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Asthma control in preschoolers: a strong predictor of long-term morbidity 学龄前儿童哮喘控制:长期发病的一个强有力的预测因子

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.oa4971

C. Longo, L. Blais, M. Brownell, R. Platt, J. Quail, M. Sadatsafavi, Wenbin Li, H. Tavakoli, A. Tan, F. Ducharme

引用次数: 1

The Swiss Primary Ciliary Dyskinesia registry: an update 瑞士初级纤毛运动障碍登记:更新

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa299

M. Goutaki, F. Halbeisen, Agatha Wisse, J. Barben, C. Casaulta, C. Clarenbach, A. Jung, P. Latzin, R. Lazor, Dagmar Lin, Marco Lurà, I. Rochat, S. Tschanz, Elisabeth Maurer, C. Kuehni

引用次数: 0

Clinical outcome measures for use in primary ciliary dyskinesia research: a scoping systematic review 用于原发性纤毛运动障碍研究的临床结果测量:一项范围系统评价

Paediatric respiratory epidemiology Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa307

B. Rubbo, F. Gahleitner, C. Jackson, M. Goutaki, F. Halbeisen, J. Hueppe, L. Behan, G. Thouvenin, C. Kuehni, P. Latzin, J. Lucas

引用次数: 0