Nanomedicine : nanotechnology, biology, and medicine最新文献

Constructing a blood contact material surface with selective adhesion of multiple cells using TiO2 photocatalytic oxidation of polydopamine

IF 4.2 2区医学

Nanomedicine : nanotechnology, biology, and medicine Pub Date : 2025-04-01 DOI: 10.1016/j.nano.2025.102815

Luying Liu PhD , Peng Ye ME , Jingmei Pan PhD , Zhongyu Zhang PhD , Ziqi Zhou BE , Sheng Dai PhD , Yue Luo MD , Ping Yang PhD

{"title":"Constructing a blood contact material surface with selective adhesion of multiple cells using TiO2 photocatalytic oxidation of polydopamine","authors":"Luying Liu PhD , Peng Ye ME , Jingmei Pan PhD , Zhongyu Zhang PhD , Ziqi Zhou BE , Sheng Dai PhD , Yue Luo MD , Ping Yang PhD","doi":"10.1016/j.nano.2025.102815","DOIUrl":"10.1016/j.nano.2025.102815","url":null,"abstract":"<div><div>The effective measure to promoting endothelial repair is to construct a surface similar to that of normal vascular on blood contact materials. The construction of cell culture platform regulating platelets, endothelial cells (ECs) and Smooth muscle cells (SMCs) may provide more help to promote endothelial repair. In this work, a novel versatile cell research platform UV-P-PDA@TiO<sub>2</sub> was constructed by magnetron sputtering and photoetching. The surface of UV-P-PDA@TiO<sub>2</sub> was evaluated by materials science methods such as FTIR, Raman, Micro BCA and WCA, and cell culture was performed on the surface. These results indicated that UV-P-PDA@TiO<sub>2</sub> platform regulated the cellular behavior of platelets, ECs, and SMCs, achieved selective adhesion, and exhibited orientation. The advantage of histocompatibility was demonstrated by <em>in vivo</em> tests that UV-P-PDA@TiO<sub>2</sub> had pattern stability and inhibited tissue proliferation. Conceivably, the regulating the multicellular UV-P-PDA @ TiO<sub>2</sub> culture platform may provide a versatile surface engineering strategy for biomaterials.</div></div>","PeriodicalId":19050,"journal":{"name":"Nanomedicine : nanotechnology, biology, and medicine","volume":"65 ","pages":"Article 102815"},"PeriodicalIF":4.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Temozolomide-loaded bacterial magnetosomes improve targeted therapy for brain tumors

IF 4.2 2区医学

Nanomedicine : nanotechnology, biology, and medicine Pub Date : 2025-04-01 DOI: 10.1016/j.nano.2025.102814

Amna Nisar Pharm-D , Shumaila Rauf Ph.D , Fazle Rabbi Ph.D , Laiba Ahmad Bachelor of Medicine (MBBS) , Abdur Rauf Ph.D , Abdulrahman Alshammari Ph.D , Norah A. Albekairi Ph.D , Thamer H. Albekairi Ph.D , Marcello Iriti Ph.D

{"title":"Temozolomide-loaded bacterial magnetosomes improve targeted therapy for brain tumors","authors":"Amna Nisar Pharm-D , Shumaila Rauf Ph.D , Fazle Rabbi Ph.D , Laiba Ahmad Bachelor of Medicine (MBBS) , Abdur Rauf Ph.D , Abdulrahman Alshammari Ph.D , Norah A. Albekairi Ph.D , Thamer H. Albekairi Ph.D , Marcello Iriti Ph.D","doi":"10.1016/j.nano.2025.102814","DOIUrl":"10.1016/j.nano.2025.102814","url":null,"abstract":"<div><div>Novel active-targeting nano-therapeutic, Temozolomide-loaded magnetosomes conjugate has been developed to address the challenges of high metastatic rates and recurrence of tumors due to tumor circulating cells. Temozolomide-loaded magnetosomes as drug conjugate were characterized through a scanning electron microscope, Zeta-sizer, and UV–visible spectroscopy. The anti-tumor activity was studied in vitro (Cell viability, Cell proliferation, and flow cytometry) <strong>and</strong> in vivo (Xenograft tumor model). The particle size of temozolomide-coated magnetosomes is larger than that of uncoated magnetosomes. The zeta potential decreased to −11.2 from −21.6 mV for Temozolomide- magnetosomes conjugates. The drug-coated magnetosomes can sustain drug release, reducing the frequency of administration and enhancing their therapeutic effect. The study found that Temozolomide-loaded magnetosomes conjugate showed enhanced tumor cytotoxicity and apoptosis than free Temozolomide or magnetosomes. In vivo, the treatment of mice with Temozolomide-loaded magnetosomes inhibited tumor growth to 405.25 mm<sup>3</sup> and reduced tumor weight (0.60 g), with fewer juvenile cells and increased necrotic area. These results suggest Bacterial magnetosomes as an appropriate choice for cancer therapy since they may be superior drug carriers with increased therapeutic efficacy and no undesirable side effects to the brain.</div></div>","PeriodicalId":19050,"journal":{"name":"Nanomedicine : nanotechnology, biology, and medicine","volume":"65 ","pages":"Article 102814"},"PeriodicalIF":4.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanogels conjugated with cell-penetrating peptide as drug delivery vehicle for treating urinary tract infections

IF 4.2 2区医学

Nanomedicine : nanotechnology, biology, and medicine Pub Date : 2025-02-28 DOI: 10.1016/j.nano.2025.102812

Humberto D. Escobedo Ph.D , Nicholas Zawadzki BS , James K.A. Till Ph.D , Andres Vazquez-Torres D.V.M., Ph.D , Guankui Wang Ph.D , Dmitri Simberg Ph.D , David J. Orlicky Ph.D , Joshua Johnson Ph.D , Marsha K. Guess MD, MS , Devatha P. Nair Ph.D , Michael J. Schurr Ph.D

{"title":"Nanogels conjugated with cell-penetrating peptide as drug delivery vehicle for treating urinary tract infections","authors":"Humberto D. Escobedo Ph.D , Nicholas Zawadzki BS , James K.A. Till Ph.D , Andres Vazquez-Torres D.V.M., Ph.D , Guankui Wang Ph.D , Dmitri Simberg Ph.D , David J. Orlicky Ph.D , Joshua Johnson Ph.D , Marsha K. Guess MD, MS , Devatha P. Nair Ph.D , Michael J. Schurr Ph.D","doi":"10.1016/j.nano.2025.102812","DOIUrl":"10.1016/j.nano.2025.102812","url":null,"abstract":"<div><div>Among hospital–acquired infections, <em>Pseudomonas aeruginosa-</em>associated urinary tract infections (UTIs) are mainly caused by indwelling urethral catheters (catheter-associated UTIs or CAUTIs) and are difficult to treat, resulting in high rates of morbidity among hospitalized patients. While antibiotics can successfully treat bacteria in the bladder lumen, they are inefficient at crossing stratified urothelium plasma membranes to kill persistent intracellular bacterial communities (IBCs). Herein, we introduce an approach to target UTI IBCs by locally delivering the antibiotic gentamicin via polymeric nanogels conjugated with a cell-penetrating peptide Cys-Gly-Lys-Arg-Lys. This novel approach delivered ~36 % more intracellular gentamicin compared to drug delivered in solution in vitro. In an acute UTI murine model, the nanogel cell-penetrating peptide drug delivery system facilitated the transport of gentamicin into the urothelium and resulted in >90 % clearance of a uropathogenic <em>P. aeruginosa</em> clinical strain in vivo.</div></div>","PeriodicalId":19050,"journal":{"name":"Nanomedicine : nanotechnology, biology, and medicine","volume":"65 ","pages":"Article 102812"},"PeriodicalIF":4.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced rivastigmine delivery through nanoemulsion and pyridoxine supplementation: An in-vivo study on Alzheimer's disease intervention

IF 4.2 2区医学

Nanomedicine : nanotechnology, biology, and medicine Pub Date : 2025-02-28 DOI: 10.1016/j.nano.2025.102810

Harekrishna Roy PhD , Balaji Maddiboyina PhD , Sisir Nandi PhD , Swati Srungarapati PhD , Bhabani Shankar Nayak PhD , Nirmala Jyothi Gade M Pharm , Tummala Lokeswari Naga Sai Anjana M Pharm , Kammula Mounika Vinayasri M Pharm , Asha Gummadi M Pharm , Shaik Haseena M Pharm

{"title":"Enhanced rivastigmine delivery through nanoemulsion and pyridoxine supplementation: An in-vivo study on Alzheimer's disease intervention","authors":"Harekrishna Roy PhD , Balaji Maddiboyina PhD , Sisir Nandi PhD , Swati Srungarapati PhD , Bhabani Shankar Nayak PhD , Nirmala Jyothi Gade M Pharm , Tummala Lokeswari Naga Sai Anjana M Pharm , Kammula Mounika Vinayasri M Pharm , Asha Gummadi M Pharm , Shaik Haseena M Pharm","doi":"10.1016/j.nano.2025.102810","DOIUrl":"10.1016/j.nano.2025.102810","url":null,"abstract":"<div><div>Nanoemulsions are nanostructured material and stabilized colloidal in nature evolved as a highly desirable mechanism for the delivery of drugs. Our objective of the study deals with a successful Rivastigmine (RSG) loaded nanoemulsion which can effectively progress the treatment of AD patients. We developed nanoemulsion containing RSG by combining pyridoxine, an essential vitamin supplement for central nervous system development, with linseed oil, which functioned as the lipophilic phase in the nanoemulsion formulation. The optimal formulation having globular size of 202.3 nm was further evaluated by various analytical techniques, including zeta potential analysis, ATR, DSC, and XRD study. The study utilized the Morris Water Maze (MWM) model to assess the cognitive abilities of Long-Evans rats. The current investigation establishes that the utilization of RSG nanoemulsion incorporating blend of linseed oil and pyridoxine which reduced travel distance in animal mode and can be successfully contribute to therapeutic advancements in patients with AD.</div></div>","PeriodicalId":19050,"journal":{"name":"Nanomedicine : nanotechnology, biology, and medicine","volume":"65 ","pages":"Article 102810"},"PeriodicalIF":4.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143526763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Silver nanoparticles enhance neutron radiation sensitivity in cancer cells: An in vitro study

IF 4.2 2区医学

Nanomedicine : nanotechnology, biology, and medicine Pub Date : 2025-02-28 DOI: 10.1016/j.nano.2025.102813

Evgenii V. Plotnikov Ph.D. , Anastasia G. Drozd Master degree , Anton A. Artamonov Ph.D. , Maria S. Larkina Prof. Ph.D. , Mikhail V. Belousov Prof. Ph.D. , Ivan V. Lomov Ph.D. , D. Garibo Ph.D. , Alexey N. Pestryakov Prof. Ph.D. , Nina Bogdanchikova Prof. Ph.D.

{"title":"Silver nanoparticles enhance neutron radiation sensitivity in cancer cells: An in vitro study","authors":"Evgenii V. Plotnikov Ph.D. , Anastasia G. Drozd Master degree , Anton A. Artamonov Ph.D. , Maria S. Larkina Prof. Ph.D. , Mikhail V. Belousov Prof. Ph.D. , Ivan V. Lomov Ph.D. , D. Garibo Ph.D. , Alexey N. Pestryakov Prof. Ph.D. , Nina Bogdanchikova Prof. Ph.D.","doi":"10.1016/j.nano.2025.102813","DOIUrl":"10.1016/j.nano.2025.102813","url":null,"abstract":"<div><div>Growing interest in cancer radiotherapy has led to the application of nanoparticles as radiosensitizers. Here, we, for the first time, present the results of the radiosensitizing properties of silver nanoparticles (AgNPs) (possessing low toxicity towards human body) against cancer cells under neutron irradiation. Five standard cancer cultures (including glioblastoma, known for its resistance to conventional photon radiation) were used to evaluate the radiosensitizing properties of AgNPs suing MTT test, flow cytometry, and optical fluorescence microscopy. Neutron irradiation was applied in the absorbed dose of 0.5–1.5 Gy with an average neutron energy of 7.5 MeV. AgNPs increased the irradiation efficiency with the radiosensitivity enhancement ratios 1.02–2.32, for glioblastoma with ratios 1.22–1.47. It was revealed that at 1.5 Gy, AgNP-induced cytotoxicity made a significant contribution to the total observed radiosensitizer effect: on average, for five cell types, 29.8 and 96.2 % at the AgNP concentration of 0.2 and 1.6 μg/mL, respectively.</div></div>","PeriodicalId":19050,"journal":{"name":"Nanomedicine : nanotechnology, biology, and medicine","volume":"65 ","pages":"Article 102813"},"PeriodicalIF":4.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasmall maghemite nanoparticles as MRI contrast agent: Unique combination of aggregation stability, low toxicity, and tumor visualization

IF 4.2 2区医学

Nanomedicine : nanotechnology, biology, and medicine Pub Date : 2025-02-28 DOI: 10.1016/j.nano.2025.102811

Ekaterina O. Moiseeva MSc , Vsevolod A. Skribitsky MSc , Yulia A. Finogenova MD , Sergei V. German PhD , Kristina E. Shpakova MSc , Igor S. Sergeev MSc , Daria A. Terentyeva MSc , Olga A. Sindeeva PhD , Oleg A. Kulikov PhD , Alexey A. Lipengolts PhD , Elena Yu. Grigorieva DSc , Dmitry A. Gorin DSc

{"title":"Ultrasmall maghemite nanoparticles as MRI contrast agent: Unique combination of aggregation stability, low toxicity, and tumor visualization","authors":"Ekaterina O. Moiseeva MSc , Vsevolod A. Skribitsky MSc , Yulia A. Finogenova MD , Sergei V. German PhD , Kristina E. Shpakova MSc , Igor S. Sergeev MSc , Daria A. Terentyeva MSc , Olga A. Sindeeva PhD , Oleg A. Kulikov PhD , Alexey A. Lipengolts PhD , Elena Yu. Grigorieva DSc , Dmitry A. Gorin DSc","doi":"10.1016/j.nano.2025.102811","DOIUrl":"10.1016/j.nano.2025.102811","url":null,"abstract":"<div><div>Iron oxide nanoparticles are a promising candidate for the dual-mode MRI contrast agent, however most of them have limited circulation time and predominant negative contrast. We developed citric acid stabilized superparamagnetic maghemite nanoparticles (CA-SPMNs) with size 3.2 ± 0.7 nm with intense positive contrast. Co-precipitation reactions under well-controlled conditions in the automatic chemical reactor have carried out the synthesis. We found an encouraging correlation between aggregate formation kinetics in biological media and <em>in vitro</em> cytotoxicity results and <em>in vivo</em> circulation time. A cytotoxicity test showed the mouse fibroblast viability over 80 % for iron doses exceeding 1 mg/mL. CA-SPMNs have a low r<sub>2</sub>/r<sub>1</sub> ratio, exhibiting positive contrast. Using <em>in vivo</em> MRI we demonstrated that CA-SPMNs circulate in the blood for 12–24 h, enabling blood vessel and tumor visualization, and partial renal clearance. Finally, CA-SPMNs show promise as effective MRI contrast agents, enabling differentiation between normal and pathological tissues.</div></div>","PeriodicalId":19050,"journal":{"name":"Nanomedicine : nanotechnology, biology, and medicine","volume":"65 ","pages":"Article 102811"},"PeriodicalIF":4.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Machine learning-driven Raman spectroscopy: A novel approach to lipid profiling in diabetic kidney disease

IF 4.2 2区医学

Nanomedicine : nanotechnology, biology, and medicine Pub Date : 2025-02-01 DOI: 10.1016/j.nano.2025.102804

Adrianna Kryska MSc , Magdalena Sawic MSc , Joanna Depciuch PhD , Piotr Sosnowski PhD , Klaudia Szałaj MSc , Wiesław Paja PhD , Maryna Khalavka PhD , Anna Sroka-Bartnicka PhD

{"title":"Machine learning-driven Raman spectroscopy: A novel approach to lipid profiling in diabetic kidney disease","authors":"Adrianna Kryska MSc , Magdalena Sawic MSc , Joanna Depciuch PhD , Piotr Sosnowski PhD , Klaudia Szałaj MSc , Wiesław Paja PhD , Maryna Khalavka PhD , Anna Sroka-Bartnicka PhD","doi":"10.1016/j.nano.2025.102804","DOIUrl":"10.1016/j.nano.2025.102804","url":null,"abstract":"<div><div>Diabetes mellitus is a chronic metabolic disease that increasingly affects people every year. It is known that with its progression and poor management, metabolic changes can lead to organ dysfunctions, including kidneys. The study aimed to combine Raman spectroscopy and biochemical lipid profiling, complemented by machine learning (ML) techniques to evaluate chemical composition changes in kidneys induced by Type 2 Diabetes mellitus (T2DM). Raman spectroscopy identified significant differences in lipid content and specific molecular vibrations, with the 1777 cm<sup>−1</sup> band emerging as a potential spectroscopic marker for diabetic kidney damage. The integration of ML algorithms improved the analysis, providing high accuracy, selectivity, and specificity in detecting these changes. Moreover, lipids metabolic profiling revealed distinct variations in the concentration of 11 phosphatydylocholines and 9 acyl-alkylphosphatidylcholines glycerophospholipids. Importantly, the correlation between Raman data and lipids metabolic profiling differed for control and T2DM groups. This study underscores the combined power of Raman spectroscopy and ML in offering a low-cost, fast, precise, and comprehensive approach to diagnosing and monitoring diabetic nephropathy, paving the way for improved clinical interventions. However, taking into account small number of data related to ethical committee approvals, the study should be verified on a larger number of cases.</div></div>","PeriodicalId":19050,"journal":{"name":"Nanomedicine : nanotechnology, biology, and medicine","volume":"64 ","pages":"Article 102804"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143040414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving lipid nanoparticles delivery efficiency of macrophage cells by using immunomodulatory small molecules

IF 4.2 2区医学

Nanomedicine : nanotechnology, biology, and medicine Pub Date : 2025-02-01 DOI: 10.1016/j.nano.2025.102809

Lirong Yi PhD , Ziyan Zhang MSc , Tian He MSc , Yating Li MSc , Weiwei Yao PhD , Gangcai Xie PhD , Wenqing Li PhD

引用次数: 0

Soluble microneedle acupuncture patches containing melittin liposomes for the percutaneous treatment of rheumatoid arthritis

IF 4.2 2区医学

Nanomedicine : nanotechnology, biology, and medicine Pub Date : 2025-02-01 DOI: 10.1016/j.nano.2025.102806

Tong Xiong Master of Medicine (MSc degree) , Du Li Master of Medicine (MSc degree) , Juanjuan Ren Master of Medicine (MSc degree) , Chuncheng Chen Master of Medicine (MSc degree) , Shijie Li Doctor of Medicine (PhD) , Zhuoyue Song Doctor of Medicine (PhD) , Nenggui Xu Doctor of Medicine (PhD) , Tao Liu Doctor of Engineering degree , Shihui Liu Master of Engineering (M.Eng.) degree

{"title":"Soluble microneedle acupuncture patches containing melittin liposomes for the percutaneous treatment of rheumatoid arthritis","authors":"Tong Xiong Master of Medicine (MSc degree) , Du Li Master of Medicine (MSc degree) , Juanjuan Ren Master of Medicine (MSc degree) , Chuncheng Chen Master of Medicine (MSc degree) , Shijie Li Doctor of Medicine (PhD) , Zhuoyue Song Doctor of Medicine (PhD) , Nenggui Xu Doctor of Medicine (PhD) , Tao Liu Doctor of Engineering degree , Shihui Liu Master of Engineering (M.Eng.) degree","doi":"10.1016/j.nano.2025.102806","DOIUrl":"10.1016/j.nano.2025.102806","url":null,"abstract":"<div><div>Bee venom acupuncture (BVA) offers therapeutic potential for rheumatoid arthritis (RA) but faces challenges from pain and allergies linked to live bee stings. A key hurdle is melittin (Mel), bee venom's main anti-inflammatory component, which degrades rapidly when orally ingested, leading to decreased efficacy and increased toxicity. This study proposes a solution by encapsulating melittin in liposomes to enhance stability and lessen side effects, expanding its clinical applicability. Additionally, the advancement of microneedle technology, which bypasses gastrointestinal issues by targeting the stratum corneum, opens a novel pathway for RA treatment. Employing soluble microneedles loaded with melittin-encapsulated liposomes (Mel-Lip) enables effective transdermal delivery. Results from an adjuvant-induced RA animal model show that Mel-Lip microneedles improve foot health, repair cartilage, and lower inflammatory markers, highlighting microneedling with transdermal nanocarriers as a promising, patient-friendly approach for RA management.</div></div>","PeriodicalId":19050,"journal":{"name":"Nanomedicine : nanotechnology, biology, and medicine","volume":"64 ","pages":"Article 102806"},"PeriodicalIF":4.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143040415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to “A light-up “G-quadruplex nanostring” for label-free and selective detection of miRNA via duplex-specific nuclease mediated tandem rolling circle amplification” [Nanomed.: Nanotechnol. Biol. Med. 32C (2021) 102339]

IF 4.2 2区医学

Nanomedicine : nanotechnology, biology, and medicine Pub Date : 2025-02-01 DOI: 10.1016/j.nano.2025.102808

Li-qi Liu PhD , Fei Yin PhD , Yu Lu MD , Xi-luan Yan PhD , Ching-Chou Wu PhD , Xia Li PhD , Chenzhong Li PhD

引用次数: 0