Molecules最新文献_第9页

Benefit of an Ultrasonic Irradiation on the Depollution by Washing of Nickel- or Zinc-Contaminated Vermiculite.

IF 4.2 2区化学

Molecules Pub Date : 2025-02-28 DOI: 10.3390/molecules30051110

Antoine Leybros, Sophie Herr, Rita Salameh, Rachel Pflieger

{"title":"Benefit of an Ultrasonic Irradiation on the Depollution by Washing of Nickel- or Zinc-Contaminated Vermiculite.","authors":"Antoine Leybros, Sophie Herr, Rita Salameh, Rachel Pflieger","doi":"10.3390/molecules30051110","DOIUrl":"10.3390/molecules30051110","url":null,"abstract":"Pollution of soil by heavy metals has become a critical environmental issue. This study investigated an innovative approach to heavy metals removal, focusing on the desorption of nickel and zinc from vermiculite using a combination of leaching and ultrasonic (US) irradiation at 20 or 362 kHz. When 0.1 M HCl was used as a washing solution, Zn2+ desorption yields around 85% were obtained in all conditions. Under 20 kHz US, fragmentation of the particles occurred, leading to the formation of new sites where released Zn2+ could sorb, allowing improved decontamination by cation exchange. Even higher yields were obtained with the biobased citric acid. Ni2+ desorption yields were lower due to its distribution in less accessible Tessier fractions. They significantly increased under US, especially at 362 kHz. It is shown that US leads to transfer of the contaminant from less accessible fractions (in particular the residual one) to more accessible ones, and that at low frequency, new sorption sites are created by fragmentation, leading to readsorption in the exchangeable fraction. This study brought to light for the first time the potential of high-frequency US in enhancing soil washing, to a higher extent compared to low-frequency (20-50 kHz) US.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143616244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advanced TiO₂-Based Photocatalytic Systems for Water Splitting: Comprehensive Review from Fundamentals to Manufacturing.

IF 4.2 2区化学

Molecules Pub Date : 2025-02-28 DOI: 10.3390/molecules30051127

Tarek Ahasan, E M N Thiloka Edirisooriya, Punhasa S Senanayake, Pei Xu, Huiyao Wang

{"title":"Advanced TiO2-Based Photocatalytic Systems for Water Splitting: Comprehensive Review from Fundamentals to Manufacturing.","authors":"Tarek Ahasan, E M N Thiloka Edirisooriya, Punhasa S Senanayake, Pei Xu, Huiyao Wang","doi":"10.3390/molecules30051127","DOIUrl":"10.3390/molecules30051127","url":null,"abstract":"The global imperative for clean energy solutions has positioned photocatalytic water splitting as a promising pathway for sustainable hydrogen production. This review comprehensively analyzes recent advances in TiO2-based photocatalytic systems, focusing on materials engineering, water source effects, and scale-up strategies. We recognize the advancements in nanoscale architectural design, the engineered heterojunction of catalysts, and cocatalyst integration, which have significantly enhanced photocatalytic efficiency. Particular emphasis is placed on the crucial role of water chemistry in photocatalytic system performance, analyzing how different water sources-from wastewater to seawater-impact hydrogen evolution rates and system stability. Additionally, the review addresses key challenges in scaling up these systems, including the optimization of reactor design, light distribution, and mass transfer. Recent developments in artificial intelligence-driven materials discovery and process optimization are discussed, along with emerging opportunities in bio-hybrid systems and CO2 reduction coupling. Through critical analysis, we identify the fundamental challenges and propose strategic research directions for advancing TiO2-based photocatalytic technology toward practical implementation. This work will provide a comprehensive framework for exploring advanced TiO2-based composite materials and developing efficient and scalable photocatalytic systems for multifunctional simultaneous hydrogen production.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143616291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and Evaluation of Boron-Containing Heterocyclic Compounds with Antimicrobial and Anticancer Activities.

IF 4.2 2区化学

Molecules Pub Date : 2025-02-28 DOI: 10.3390/molecules30051117

João Lucas Bruno Prates, Samanta de Matos Silva, Kaila Petrolina Medina-Alarcón, Kelvin Sousa Dos Santos, Jenyffie Araujo Belizario, Juliana Romano Lopes, Freddy Humberto Marin-Dett, Debora Leite Campos, Maria José Soares Mendes Giannini, Ana Marisa Fusco-Almeida, Paula Aboud Barbugli, Fernando Rogério Pavan, Jean Leandro Dos Santos

{"title":"Synthesis and Evaluation of Boron-Containing Heterocyclic Compounds with Antimicrobial and Anticancer Activities.","authors":"João Lucas Bruno Prates, Samanta de Matos Silva, Kaila Petrolina Medina-Alarcón, Kelvin Sousa Dos Santos, Jenyffie Araujo Belizario, Juliana Romano Lopes, Freddy Humberto Marin-Dett, Debora Leite Campos, Maria José Soares Mendes Giannini, Ana Marisa Fusco-Almeida, Paula Aboud Barbugli, Fernando Rogério Pavan, Jean Leandro Dos Santos","doi":"10.3390/molecules30051117","DOIUrl":"10.3390/molecules30051117","url":null,"abstract":"Organoboron compounds, especially those containing boronic acid and benzoxaborole in their structure, have been gaining prominence in medicinal chemistry, following the FDA approval of tavaborole for the treatment of onychomycosis and bortezomib for multiple myeloma. The antimicrobial and anticancer effects of organoboron compounds motivate the investigation of the effects of the novel derivatives described here. A total of fourteen new boronic derivatives were synthesized and characterized using analytical methods. The antimicrobial activities were evaluated against M. tuberculosis (Mtb) H37Rv strains and fungal dermatophytes (C. albicans, ATCC 90028; T. rubrum, ATCC 28189; and T. mentagrophytes, ATCC 11481), while the anticancer effect was evaluated against oral squamous cell carcinoma (SCC) cell lines. Several promising boron-containing prototypes were identified, providing a foundation for further molecular optimization in the development of new antimicrobial and anticancer compounds.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143616436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Study of the Catalytic System H₃PW₁₂O₄₀/Quaternary Phosphonium Salts for the Epoxidation of Fatty Acid Methyl Esters-The Effect of the Molar Ratio of Hydrogen Peroxide to the Double Bond.

IF 4.2 2区化学

Molecules Pub Date : 2025-02-28 DOI: 10.3390/molecules30051109

Marlena Musik, Ewa Janus, Robert Pełech

{"title":"A Study of the Catalytic System H3PW12O40/Quaternary Phosphonium Salts for the Epoxidation of Fatty Acid Methyl Esters-The Effect of the Molar Ratio of Hydrogen Peroxide to the Double Bond.","authors":"Marlena Musik, Ewa Janus, Robert Pełech","doi":"10.3390/molecules30051109","DOIUrl":"10.3390/molecules30051109","url":null,"abstract":"In the present work, the epoxidation of fatty acid methyl esters (biodiesel or FAMEs) with an iodine number of 96.4 g/100 g and containing approximately 11% palmitic acid, 4% stearic acid, 51% oleic acid, 25% linoleic acid, and 5% linolenic acid was studied with an aqueous H2O2 solution and different quaternary phosphonium salts (QPSs) combined with the phosphotungstic heteropolyacid (HPA) H3PW12O40 in a biphasic system. The effect of the molar ratio of H2O2:C=C on the epoxidation of FAMEs was investigated. The effect of the molar ratio of H2O2:C=C on the epoxy number (EN) and iodine number (IN) was measured. Multiple regression analysis methods were used to determine the regression model describing the influence of the various independent variables. In the results obtained, it was found that the highest yields were obtained for [P6][Phosf]. The optimum conditions for the epoxidation process with the systems used were a time range of 30 ± 4 min and a H2O2/double bond molar ratio in the range of 1.8 ± 0.2. The formation of epoxidised fatty acid methyl esters (E-FAMEs) was confirmed by FT-IR, 1H NMR and 13C NMR analyses. In the FT-IR spectrum of the E-FAMEs, epoxy ring vibration signals were identified at 826 cm-1. In the 1H NMR spectrum, signals appeared in the range of 3.25-3.00 ppm, corresponding to epoxy ring formation in biodiesel, and in the range of 60-55 ppm in the 13C NMR spectrum.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143616211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Viologen-Based Ionic Porous Organic Polymers for Efficient Removal of Anionic Dyes and Hexavalent Chromium (Cr (VI)) from Water.

IF 4.2 2区化学

Molecules Pub Date : 2025-02-28 DOI: 10.3390/molecules30051123

Meihan Lu, Lijun Sun, Dongxin Yang, Zewen Nie, Weitao Gong

{"title":"New Viologen-Based Ionic Porous Organic Polymers for Efficient Removal of Anionic Dyes and Hexavalent Chromium (Cr (VI)) from Water.","authors":"Meihan Lu, Lijun Sun, Dongxin Yang, Zewen Nie, Weitao Gong","doi":"10.3390/molecules30051123","DOIUrl":"10.3390/molecules30051123","url":null,"abstract":"Water pollution is a critical environmental issue in modern society, and adsorption is recognized as a straightforward and efficient water purification technique. In this study, three new viologen-based ionic porous organic polymers were designed and successfully synthesized via a simple approach, and their adsorption properties for water pollutants were evaluated. The cationic nature of these polymers, coupled with their large conjugated π-electron system, physicochemical stability, and aromatic backbone, contributes to their high adsorption capacity and rapid adsorption efficiency for anionic contaminants in water such as Methyl Orange, Congo Red, and Cr (VI). The polymers exhibited maximum adsorption capacities of 1617 mg/g for MO, 3734 mg/g for CR, and 530.22 mg/g for Cr (VI), surpassing most previously reported adsorbents. Furthermore, the polymers maintained a high removal rate even in the presence of competing anions. Effective separation of anionic dyes from mixed solutions could be achieved through simple filtration. These characteristics make them promising candidates for water purification applications.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143616309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heterocyclic Antidepressants with Antimicrobial and Fungicide Activity.

IF 4.2 2区化学

Molecules Pub Date : 2025-02-27 DOI: 10.3390/molecules30051102

Darya Zolotareva, Alexey Zazybin, Yelizaveta Belyankova, Sarah Bayazit, Anuar Dauletbakov, Tulegen Seilkhanov, Ulan Kemelbekov, Murat Aydemir

引用次数: 0

From "Maraschino" to Cell Cultures: A Deep Study on Prunus cerasus L. Cell Culture Juices.

IF 4.2 2区化学

Molecules Pub Date : 2025-02-27 DOI: 10.3390/molecules30051089

Vanessa Dalla Costa, Anna Piovan, Ina Varfaj, Maria Carla Marcotullio, Paola Brun, Raffaella Filippini

{"title":"From \"Maraschino\" to Cell Cultures: A Deep Study on Prunus cerasus L. Cell Culture Juices.","authors":"Vanessa Dalla Costa, Anna Piovan, Ina Varfaj, Maria Carla Marcotullio, Paola Brun, Raffaella Filippini","doi":"10.3390/molecules30051089","DOIUrl":"10.3390/molecules30051089","url":null,"abstract":"Prunus cerasus var. Marasca (Rosaceae) is an important Croatian cultivar, known wordwide for the production of Luxardo maraschino liqueur, which occurs in the eastern Po Valley of Italy. Besides liqueur, Marasca is attractive for its beneficial effects on human health and well-being. The undifferentiated in vitro cell cultures of Marasca were investigated as a source of healthy products. The in vitro conditions for obtaining callus and suspension cultures under photoperiod were defined. The cell lines were evaluated for growth rate, total phenol and proanthocyanidin contents, and antioxidant activities via colorimetric assays. The best cell lines were also subcultured in darkness, studying the importance of the light parameter in the possible industrial scaling-up. The juices extracted from the obtained biomasses were analyzed by LC-DAD-MS and six flavanone derivatives, among which naringenin and its glucoside were identified. The quantitative analysis, pursued during the cell growth cycle, revealed that the flavanone content was higher at the end of the growth cycle (28th day) and that the total content of identified flavanone compounds varied from 17.22 to 79.22 μg/mL of juice. The results of the antioxidant and anti-inflammatory activities on Caco-2 cells support the potential applications of this material in human health.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143616147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comprehensive Review of the Phytochemistry, Pharmacology and Other Applications of Euphorbiae Humifusae Herba.

IF 4.2 2区化学

Molecules Pub Date : 2025-02-27 DOI: 10.3390/molecules30051094

Jian Xiao, Hong Gu, Jiaqing Zhang, Yuqian Xue, Yunyi Chen, Weizhong Zhu, Hong Zhang, Boyi Fan, Wenli Wang

{"title":"A Comprehensive Review of the Phytochemistry, Pharmacology and Other Applications of Euphorbiae Humifusae Herba.","authors":"Jian Xiao, Hong Gu, Jiaqing Zhang, Yuqian Xue, Yunyi Chen, Weizhong Zhu, Hong Zhang, Boyi Fan, Wenli Wang","doi":"10.3390/molecules30051094","DOIUrl":"10.3390/molecules30051094","url":null,"abstract":"Euphorbiae Humifusae Herba (EHH) is a globally distributed plant commonly utilized in traditional Chinese medicine (TCM) and health food within China. The dried aerial parts of EHH are well-recognized as health foods for the management of diarrhea and other intestinal diseases. Known for its therapeutic effects, such as heat-clearing, detoxification, blood cooling, hemostasis, dampness, elimination, and jaundice relief, EHH has yielded 197 bioactive compounds identified to date, including terpenoids, flavonoids, phenolic acids, tannins, alkaloids, sterols, lactones, coumarins, and other constituents, with flavonoids and terpenoids, highlighting its wide-ranging pharmacological properties and medicinal significance. Despite its popularity in research, limited systematic and comprehensive information has been provided on the EHH. Therefore, we provide an in-depth overview of EHH, covering its botanical characteristics, traditional uses, phytochemical composition, pharmacological properties, and additional applications. Furthermore, it addresses the current challenges and limitations in modern research on EHH, offering critical perspectives to guide future studies in this field.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143616179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Jiang et al. Preparation of Pinoresinol and Dehydrodiconiferyl Alcohol from Eucommiae Cortex Extract by Fermentation with Traditional Mucor. Molecules 2024, 29, 2979.

IF 4.2 2区化学

Molecules Pub Date : 2025-02-27 DOI: 10.3390/molecules30051081

Wenyi Jiang, Zhengyou He, Ruijiao Yao, Zhiyang Chen, Xia Zeng, Miao Zheng, Jing Wang, Jia Li, Yong Jiang

引用次数: 0

Preparation, Structure, Function, and Application of Dietary Polysaccharides from Polygonatum sibiricum in the Food Industry: A Review.

IF 4.2 2区化学

Molecules Pub Date : 2025-02-27 DOI: 10.3390/molecules30051098

Peilin Li, Huimin Yao, Hao Yue, Jiali Huang, Qi Wang, Chuanbo Ding, Lina Ma, Xinglong Liu, Min Yang

{"title":"Preparation, Structure, Function, and Application of Dietary Polysaccharides from Polygonatum sibiricum in the Food Industry: A Review.","authors":"Peilin Li, Huimin Yao, Hao Yue, Jiali Huang, Qi Wang, Chuanbo Ding, Lina Ma, Xinglong Liu, Min Yang","doi":"10.3390/molecules30051098","DOIUrl":"10.3390/molecules30051098","url":null,"abstract":"Polygonatum sibiricum is one of the most widely used plants in the Liliaceae family, renowned for its dual medicinal and edible properties. Polygonatum sibiricum polysaccharides, as the main pharmacological active ingredient of Polygonatum sibiricum, have various excellent physiological activities, such as antioxidant, immune enhancement, and hypoglycemic activities. Through extraction, purification, and structural analysis, the influence and mechanism of the molecular weight and glycosidic bonds of Polygonatum sibiricum polysaccharides on the pharmacological effects, as well as their structure-activity relationship, can be explored in more detail. With the increasing demand for Polygonatum sibiricum polysaccharide products, Polygonatum sibiricum has been widely used in the fields of medicine, food, and biochemistry, and various green and harmless products containing Polygonatum sibiricum polysaccharides have been developed for different populations. This study summarizes the extraction, structure, and function of Polygonatum sibiricum polysaccharides, and it further explores their applications in the food industry, including in beverages, health foods, additives, and food packaging. Overall, Polygonatum sibiricum polysaccharides have been proven to be a promising natural product and have been introduced into the food system. It is worth mentioning that further efforts and time are needed in the future to expand the deep processing of and feasibility research on Polygonatum sibiricum polysaccharides while exploring their bioactive molecular mechanisms in depth, laying the foundation for their product development and clinical applications.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143616371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0