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Molecular Therapy: the Journal of the American Society of Gene Therapy最新文献

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The MicroRNA-92a/Sp1/MyoD Axis Regulates Hypoxic Stimulation of Myogenic Lineage Differentiation in Mouse Embryonic Stem Cells. MicroRNA-92a/Sp1/MyoD轴调控缺氧刺激小鼠胚胎干细胞的肌源性谱系分化
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2020-01-01 DOI: 10.1016/j.ymthe.2019.08.014
Seo-Yeon Lee, Jimin Yang, J. Park, H. Shin, W. Kim, Su-Yeon Kim, E. J. Lee, Injoo Hwang, Choon-Soo Lee, Jaewon Lee, Hyo‐Soo Kim
{"title":"The MicroRNA-92a/Sp1/MyoD Axis Regulates Hypoxic Stimulation of Myogenic Lineage Differentiation in Mouse Embryonic Stem Cells.","authors":"Seo-Yeon Lee, Jimin Yang, J. Park, H. Shin, W. Kim, Su-Yeon Kim, E. J. Lee, Injoo Hwang, Choon-Soo Lee, Jaewon Lee, Hyo‐Soo Kim","doi":"10.1016/j.ymthe.2019.08.014","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.08.014","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74768340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Ablation of Immunoproteasome β5i Subunit Suppresses Hypertensive Retinopathy by Blocking ATRAP Degradation in Mice. 免疫蛋白酶体β5i亚基消融通过阻断ATRAP降解抑制小鼠高血压视网膜病变。
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2020-01-01 DOI: 10.1016/j.ymthe.2019.09.025
Shuai Wang, J. Li, Tong Wang, Jie Bai, Yun-Long Zhang, Qiu-Yue Lin, Jingmin Li, Qi Zhao, Shu-bin Guo, Hui-Hua Li
{"title":"Ablation of Immunoproteasome β5i Subunit Suppresses Hypertensive Retinopathy by Blocking ATRAP Degradation in Mice.","authors":"Shuai Wang, J. Li, Tong Wang, Jie Bai, Yun-Long Zhang, Qiu-Yue Lin, Jingmin Li, Qi Zhao, Shu-bin Guo, Hui-Hua Li","doi":"10.1016/j.ymthe.2019.09.025","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.09.025","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85516320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Transplantation of M2-Deviated Microglia Promotes Recovery of Motor Function after Spinal Cord Injury in Mice. m2偏小胶质细胞移植促进小鼠脊髓损伤后运动功能恢复。
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2020-01-01 DOI: 10.1016/j.ymthe.2019.09.004
S. Kobashi, T. Terashima, M. Katagi, Yuki Nakae, Junko Okano, Yoshihisa Suzuki, M. Urushitani, Hideto Kojima
{"title":"Transplantation of M2-Deviated Microglia Promotes Recovery of Motor Function after Spinal Cord Injury in Mice.","authors":"S. Kobashi, T. Terashima, M. Katagi, Yuki Nakae, Junko Okano, Yoshihisa Suzuki, M. Urushitani, Hideto Kojima","doi":"10.1016/j.ymthe.2019.09.004","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.09.004","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"134 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77866123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 83
Novel mRNA-Based Therapy Reduces Toxic Galactose Metabolites and Overcomes Galactose Sensitivity in a Mouse Model of Classic Galactosemia. 在经典半乳糖血症小鼠模型中，基于mrna的新疗法可减少有毒半乳糖代谢物并克服半乳糖敏感性。
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2020-01-01 DOI: 10.1016/j.ymthe.2019.09.018
B. Balakrishnan, D. An, Vi Nguyen, Christine DeAntonis, P. Martini, K. Lai
{"title":"Novel mRNA-Based Therapy Reduces Toxic Galactose Metabolites and Overcomes Galactose Sensitivity in a Mouse Model of Classic Galactosemia.","authors":"B. Balakrishnan, D. An, Vi Nguyen, Christine DeAntonis, P. Martini, K. Lai","doi":"10.1016/j.ymthe.2019.09.018","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.09.018","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72723677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 34
Improved Titer and Gene Transfer by Lentiviral Vectors Using Novel, Small β-Globin Locus Control Region Elements. 利用新型小β-珠蛋白基因座控制区元件提高滴度和慢病毒载体的基因转移。
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2020-01-01 DOI: 10.1016/j.ymthe.2019.09.020
R. Morgan, Mildred J. Unti, Bamidele Aleshe, Devin Brown, Kyle Osborne, C. Koziol, Oliver Smith, Rachel O'Brien, C. Tam, E. Miyahira, Marlene Ruiz, Jason P Quintos, S. Senadheera, R. Hollis, D. Kohn
{"title":"Improved Titer and Gene Transfer by Lentiviral Vectors Using Novel, Small β-Globin Locus Control Region Elements.","authors":"R. Morgan, Mildred J. Unti, Bamidele Aleshe, Devin Brown, Kyle Osborne, C. Koziol, Oliver Smith, Rachel O'Brien, C. Tam, E. Miyahira, Marlene Ruiz, Jason P Quintos, S. Senadheera, R. Hollis, D. Kohn","doi":"10.1016/j.ymthe.2019.09.020","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.09.020","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75981623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis. 巨噬细胞miR-34a是胆固醇外排和动脉粥样硬化的关键调节因子。
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2020-01-01 DOI: 10.1016/j.ymthe.2019.09.008
Yanyong Xu, Yang Xu, Yingdong Zhu, Huihui Sun, Cody Juguilon, Feng Li, Daping Fan, L. Yin, Yanqiao Zhang
{"title":"Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis.","authors":"Yanyong Xu, Yang Xu, Yingdong Zhu, Huihui Sun, Cody Juguilon, Feng Li, Daping Fan, L. Yin, Yanqiao Zhang","doi":"10.1016/j.ymthe.2019.09.008","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.09.008","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88331129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 66
Imaging CAR T Cell Trafficking with eDFHR as a PET Reporter Gene. eDFHR作为PET报告基因对CAR - T细胞转运的成像
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2020-01-01 DOI: 10.1016/j.ymthe.2019.10.007
M. Sellmyer, S. Richman, K. Lohith, C. Hou, Chi-Chang Weng, R. Mach, Roddy S. O’Connor, M. Milone, M. Farwell
{"title":"Imaging CAR T Cell Trafficking with eDFHR as a PET Reporter Gene.","authors":"M. Sellmyer, S. Richman, K. Lohith, C. Hou, Chi-Chang Weng, R. Mach, Roddy S. O’Connor, M. Milone, M. Farwell","doi":"10.1016/j.ymthe.2019.10.007","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.10.007","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81510272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 56
Neutrophils Deficient in Innate Suppressor IRAK-M Enhances Anti-tumor Immune Responses. 中性粒细胞先天抑制因子IRAK-M缺乏增强抗肿瘤免疫反应。
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2020-01-01 DOI: 10.1016/j.ymthe.2019.09.019
Yao Zhang, N. Diao, Christina Lee, H. Chu, Lan Bai, Liwu Li
{"title":"Neutrophils Deficient in Innate Suppressor IRAK-M Enhances Anti-tumor Immune Responses.","authors":"Yao Zhang, N. Diao, Christina Lee, H. Chu, Lan Bai, Liwu Li","doi":"10.1016/j.ymthe.2019.09.019","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.09.019","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79190922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Non-viral Gene Therapy for Stargardt Disease with ECO/pRHO-ABCA4 Self-Assembled Nanoparticles. ECO/pRHO-ABCA4自组装纳米颗粒对Stargardt病的非病毒基因治疗
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2020-01-01 DOI: 10.1016/j.ymthe.2019.09.010
Da Sun, Rebecca M. Schur, A. Sears, Songqi Gao, Amita M. Vaidya, Wenyu Sun, A. Maeda, T. Kern, K. Palczewski, Zheng-Rong Lu
{"title":"Non-viral Gene Therapy for Stargardt Disease with ECO/pRHO-ABCA4 Self-Assembled Nanoparticles.","authors":"Da Sun, Rebecca M. Schur, A. Sears, Songqi Gao, Amita M. Vaidya, Wenyu Sun, A. Maeda, T. Kern, K. Palczewski, Zheng-Rong Lu","doi":"10.1016/j.ymthe.2019.09.010","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.09.010","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79516336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
Urocortin2 Gene Transfer Improves Heart Function in Aged Mice. 尿皮质蛋白2基因转移改善老年小鼠心脏功能。
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2020-01-01 DOI: 10.1016/j.ymthe.2019.10.003
Dimosthenis Giamouridis, M. Gao, N. Lai, Tracy Guo, A. Miyanohara, W. Blankesteijn, E. Biessen, H. Hammond
{"title":"Urocortin2 Gene Transfer Improves Heart Function in Aged Mice.","authors":"Dimosthenis Giamouridis, M. Gao, N. Lai, Tracy Guo, A. Miyanohara, W. Blankesteijn, E. Biessen, H. Hammond","doi":"10.1016/j.ymthe.2019.10.003","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.10.003","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90697378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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