National Journal of Physiology, Pharmacy and Pharmacology最新文献_第6页

An epidemiological study on assessment of dementia and general health pattern among geriatric population in the rural field practice area of medical college and hospital, Kolkata 加尔各答医学院和医院农村实习区老年人群痴呆评估及总体健康模式的流行病学研究

National Journal of Physiology, Pharmacy and Pharmacology Pub Date : 2023-01-01 DOI: 10.5455/njppp.2023.13.12612202214022023

Nirmalya Manna, Avishek Bhadra, Pushpak Das, Abhishek Reja, Debasis Das

{"title":"An epidemiological study on assessment of dementia and general health pattern among geriatric population in the rural field practice area of medical college and hospital, Kolkata","authors":"Nirmalya Manna, Avishek Bhadra, Pushpak Das, Abhishek Reja, Debasis Das","doi":"10.5455/njppp.2023.13.12612202214022023","DOIUrl":"https://doi.org/10.5455/njppp.2023.13.12612202214022023","url":null,"abstract":"Background: As our age increases, different pathophysiological changes occur, which leads to geriatric syndromes in the elderly. Along with other bodily changes, psychological changes and dementia start emerging that affects day-to-day activities of the elderly people. These symptoms often get undetected due to lack of care or awareness among the geriatric population or their caregivers. Aim and Objectives: This study aims to measure the prevalence of psychiatric disorders and onset of dementia among the geriatric population in a rural area of West Bengal. Materials and Methods: An observational, descriptive, community-based, and cross-sectional study was conducted by interviewing persons aged 60 years and above residing in Banspole village during the months of April–May, 2022, using General Health Questionnaire-12 and dementia assessment by rapid test questionnaire. The data were analyzed with the Statistical Package for the Social Sciences. Results: A total of 104 respondents were interviewed (% male and % female). Most commonly found comorbidity was hypertension (48.08%), followed by chronic obstructive pulmonary disease (26.92%) and hypothyroidism (25.97%). Significant psychological morbidity was found in 49 (47.11%) persons, whereas, different levels of dementia was found in 72 (69.23%) participants. Significant associations were found between psychiatric morbidity with age and socioeconomic status, and dementia with age and marital status. Significance level was at P < 0.05. Conclusion: As it can be seen that in psychiatric morbidity is present in almost half of the participants, and dementia in almost 70% participants, but most of the times, these get undetected or overlooked. Early detection and management are the need of the hour, as these conditions causes huge economic burden on the caregivers, as well as on the government concerned.","PeriodicalId":18969,"journal":{"name":"National Journal of Physiology, Pharmacy and Pharmacology","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78220039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of effectiveness of video-assisted learning and didactic lectures in learning physiology among 1st year MBBS students 影像辅助学习与教学式教学在MBBS一年级学生生理学学习中的效果比较

National Journal of Physiology, Pharmacy and Pharmacology Pub Date : 2023-01-01 DOI: 10.5455/njppp.2023.13.02090202316022023

Minu P. Abraham, Elizabeth Vadasseril, Ceema Varghese

{"title":"Comparison of effectiveness of video-assisted learning and didactic lectures in learning physiology among 1st year MBBS students","authors":"Minu P. Abraham, Elizabeth Vadasseril, Ceema Varghese","doi":"10.5455/njppp.2023.13.02090202316022023","DOIUrl":"https://doi.org/10.5455/njppp.2023.13.02090202316022023","url":null,"abstract":"Background: Video-assisted learning makes the learning environment effective and engaging for a wide range of learners with different levels of prior knowledge and interests. Aim and Objectives: The objectives of this study were to compare the effectiveness of video-assisted learning and didactic lectures as teaching methods among 1st year MBBS students and to evaluate the feedback regarding the teaching methods from students. Materials and methods: A quasi-experimental study was conducted among 100 1st year MBBS students. A pre-test in the form of MCQ was used to assess the knowledge regarding the topic. Students were divided into two groups based on their roll numbers. Group 1 attended video-assisted learning, while the group two students attended didactic lectures. At the end of session, post-test was provided to all students to assess the knowledge gained. Feedback was taken from students at the end of session. Statistical analysis was performed using two-way repeated measures mixed ANOVA to determine whether there is any difference in the average score before and after intervention as well as between the video assisted learning and traditional method. Mann–Whitney U-test was used for comparing the feedback score between two teaching methods. Results: There was statistically significant increase in the post test scores in both the group. Although both the teaching methods were equally effective, the score change was high in the video-assisted learning group but was not statistically significant (P = 0.907). Conclusion: Video-assisted learning is an effective learning method in physiology.","PeriodicalId":18969,"journal":{"name":"National Journal of Physiology, Pharmacy and Pharmacology","volume":"140 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78281556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between awareness of sleep quality, internet addiction, and health risk among college students – A cross-sectional study 大学生睡眠质量意识、网络成瘾和健康风险之间的关系——一项横断面研究

National Journal of Physiology, Pharmacy and Pharmacology Pub Date : 2023-01-01 DOI: 10.5455/njppp.2023.13.01010202312012023

I. Ghosh, Pansy Lyall, Debalina Sahoo, Poulami Sarkar

{"title":"Relationship between awareness of sleep quality, internet addiction, and health risk among college students – A cross-sectional study","authors":"I. Ghosh, Pansy Lyall, Debalina Sahoo, Poulami Sarkar","doi":"10.5455/njppp.2023.13.01010202312012023","DOIUrl":"https://doi.org/10.5455/njppp.2023.13.01010202312012023","url":null,"abstract":"Background: At present, the cell-phone is not only a talking tool but also a virtual network connection in the individual’s daily life as people can connect easily in one click of finger through internet. Use mobile for more time may enhance the chance to several health risk and psychiatric disorders, such as anxiety disorders and depression. Aims and Objectives: The aim of this study is to access sleep quality and internet addiction in these students using Pittsburgh sleep quality index (PSQI) and internet addiction scale, respectively. Materials and Methods: The study was designed as a cross-sectional and questionnaire-based study. This study has been conducted among 300 college students in India through online, emails, and social media. Data analysis has been done on PSQI score and Internet addition score among the subjects. Results: The results of this study demonstrated significant associations of Internet addiction and poorer quality of sleep in those who have moderate and severe internet addiction than normal internet users. Conclusion: In the present study, more percentage of students met the criteria for poor sleep quality and internet addiction as well as have positive association with the different degrees of internet addiction.","PeriodicalId":18969,"journal":{"name":"National Journal of Physiology, Pharmacy and Pharmacology","volume":"151 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73155699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Distal humerus fracture and its surgical management with distal humerus dual plating 肱骨远端骨折及肱骨远端双钢板的手术治疗

National Journal of Physiology, Pharmacy and Pharmacology Pub Date : 2023-01-01 DOI: 10.5455/njppp.2023.13.08397202322082023

J. Mistry, T. Patel, Parth Patel

{"title":"Distal humerus fracture and its surgical management with distal humerus dual plating","authors":"J. Mistry, T. Patel, Parth Patel","doi":"10.5455/njppp.2023.13.08397202322082023","DOIUrl":"https://doi.org/10.5455/njppp.2023.13.08397202322082023","url":null,"abstract":"Background: Approximately 7% of all adult fractures involve the elbow. Out of these, approximately 1/3 involve the distal humerus. These fractures have bimodal age distribution with peak incidences between the age 12 and 19 years and aged more than 80 years. The result of these fractures relies on the location of the fracture, the type of fracture (comminute or simple), any displacement, and any soft-tissue damage in the immediate vicinity. Distal humerus fracture can be treated surgically using a variety of techniques, including open reduction and internal fixation with plates, limited internal fixation with screws and/or Kirschner wire, and external fixation of the bone in some circumstances with loss of surrounding skin or soft tissue. Aim and Objective: This prospective and cohort study of 30 patients with distal humerus fracture aimed at evaluating the radiological outcome and function outcome of patients treated with distal humerus dual platting. Materials and Methods: Thirty patients with distal humeral fractures had surgical treatment between March 2021 and March 2023 been investigated. Open reduction through posterior approach was used to treat patients. Olecranon osteotomy with two-column internal fixation with parallel plates, the healing of fractures, functional results, and consequences were assessed in patients. Results: After the follow-up time range from 1 month to 2 years, the average duration for union in operated patients was 24 weeks (range 18–34 weeks). Two patients came with non-union and operated again, whereas one patient came with back out of screws. Mayo elbow performance score was used to evaluate the patients’ functional outcome. Conclusion: Distal humerus fractures should be treated with dual plating through a posterior approach and an olecranon osteotomy to restore the best possible elbow function.","PeriodicalId":18969,"journal":{"name":"National Journal of Physiology, Pharmacy and Pharmacology","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72663387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation of vitamin D and bone mineral density in diabetic patients with chronic renal disease: A single institute study 糖尿病合并慢性肾病患者维生素D与骨密度的相关性:一项单机构研究

National Journal of Physiology, Pharmacy and Pharmacology Pub Date : 2023-01-01 DOI: 10.5455/njppp.2023.13.02059202306022023

Munesh Kumar, M. Yadav, Harshul Tak, D. Meena, Dhiraj Daga

{"title":"Correlation of vitamin D and bone mineral density in diabetic patients with chronic renal disease: A single institute study","authors":"Munesh Kumar, M. Yadav, Harshul Tak, D. Meena, Dhiraj Daga","doi":"10.5455/njppp.2023.13.02059202306022023","DOIUrl":"https://doi.org/10.5455/njppp.2023.13.02059202306022023","url":null,"abstract":"Background: Diabetes metabolic dysregulation directly or indirectly affects almost all the organs of the body, including renal system, bone mass, and its metabolism. Bone composition and metabolism related to minerals start to change with the onset of chronic kidney disease (CKD). Osteoporosis oftenly coexists with CKD mineral and bone disorder, which is the most common metabolic bone disease resulting in fragility fractures. To design a treatment plan and prevent complications in patients of CKD with low bone mineral density (BMD), understanding the pathophysiology of these two bone disorders is necessary. Aims and Objectives: The aim is to study the BMD and vitamin D in diabetic patients suffering from CKD and to compare the BMDs among patients with the chronicity of disease. Materials and Methods: A case–control study was conducted to study the BMD and vitamin D levels among diabetic patients with CKD attending the Medicine and Nephrology Outdoor at M.D.M. Hospital, Jodhpur India. Vitamin D estimation was done by chemiluminescence immunoassay and BMD measured by DEXA scan at lumbar spine L4–L5 for both case and control groups. Results: Incidence of low BMD and low vitamin D levels is very high in patients suffering from CKD, but it is more profound in patients suffering from diabetes. Majority of them were male and more from rural area. Mean age of patients was 50 ± 8.75 years. Overall 63.34% of CKD patients had low vitamin D level, 36.67% had osteopenia, and 36.67% had osteoporosis. Similarly, 51.62% diabetic patients had osteoporosis, 38.7% had osteopenia, and 83.86% had low vitamin D. Conclusion: Correlation of vitamin D deficiency with low BMD was statistically highly significant in patients of diabetes with CKD. Early intervention in diabetes patients to prevent low BMD and vitamin D supplements can decrease the complications of low BMD and low vitamin D.","PeriodicalId":18969,"journal":{"name":"National Journal of Physiology, Pharmacy and Pharmacology","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73680851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A study on mental distress among the undergraduate students of medical college, Kolkata 加尔各答医科大学本科生心理困扰的调查研究

National Journal of Physiology, Pharmacy and Pharmacology Pub Date : 2023-01-01 DOI: 10.5455/njppp.2023.13.03131202321032023

Nirmalya Manna, Sudipto Mondal, Anjali Jainendran, Sudipta Das

{"title":"A study on mental distress among the undergraduate students of medical college, Kolkata","authors":"Nirmalya Manna, Sudipto Mondal, Anjali Jainendran, Sudipta Das","doi":"10.5455/njppp.2023.13.03131202321032023","DOIUrl":"https://doi.org/10.5455/njppp.2023.13.03131202321032023","url":null,"abstract":"Background: Medical students are reported to have high levels of mental distress that includes problems such as anxiety, depression, and stress due to the highly competitive curriculum. In the post-pandemic era with a renewed perspective toward health system and popularization of online classes, current batch of students are exposed to diverse sources of mental distress. Aims and Objectives: Objectives of this study were to find out the socio-demographic and behavioral characteristics, family background and academic profile of the study participants, and to estimate the proportion of different varieties of mental distress among them, and to examine relationship of mental distress with sociodemographic, behavioral and academic profile. Materials and Methods: A cross-sectional observational study was performed on 649 undergraduate students by census method using depression anxiety stress scale-21 items. Results: The study participants are predominantly Hindu, urban, unmarried, hostelites, males from nuclear families and belonging to upper socioeconomic class according to Modified B.G Prasad Socioeconomic Status Scale (January 2022). The proportion of depression, anxiety, and stress among study participants was found to be 49.61%, 58.86%, and 33.13%, respectively. Proportion of mental distress was significantly higher in the age group of 21–24 years. Those who preferred to study more at night were more anxious and stressed. Stress was higher in students with addiction to gadgets too. Participants hailing from rural areas, hostelites, and paying guests were relatively more depressed. Conclusion: There is urgent need for emotional support and provision of personalized counseling for the MBBS students as unchecked mental distress can turn into severe psychological morbidity.","PeriodicalId":18969,"journal":{"name":"National Journal of Physiology, Pharmacy and Pharmacology","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73744651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Teaching faculty experiences on CBME curriculum in pharmacology – A cross-sectional questionnaire-based study 药理学CBME课程的教学经验-横断面问卷研究

National Journal of Physiology, Pharmacy and Pharmacology Pub Date : 2023-01-01 DOI: 10.5455/njppp.2023.13.11546202213022023

Rajesh Dasaraju, Pati Bapugouda, Advaitha V, A. Mark

{"title":"Teaching faculty experiences on CBME curriculum in pharmacology – A cross-sectional questionnaire-based study","authors":"Rajesh Dasaraju, Pati Bapugouda, Advaitha V, A. Mark","doi":"10.5455/njppp.2023.13.11546202213022023","DOIUrl":"https://doi.org/10.5455/njppp.2023.13.11546202213022023","url":null,"abstract":"Background: Many studies were conducted in India among the teaching faculties to understand the challenges before the implementation of new competency-based medical education (CBME) curriculum. Studies assessing the experiences and the challenges faced after its implementation are limited. Aim and Objectives: The aim of this study was to assess the experiences and the challenges faced by the teaching faculties in different medical colleges across India while implementing the new CBME curriculum in pharmacology for the MBBS batch 2019–20 students. Materials and Methods: A 19 item pre-validated questionnaire was shared to faculties through Google Forms with most of the questions having three options for answers, namely, “Agree,” “Disagree,” and “Not sure.” The time-period provided for answering the questions was 2 weeks. The data were analyzed using Microsoft Excel sheet using descriptive statistics. Results: Majority of the faculties 56 (61.5%) do not agree with national medical commission in terms of number of teaching faculty and infrastructure to implement the CBME curriculum in pharmacology. About 56 (61.5%) of the faculties felt that the number of teaching hours recommended in the CBME curriculum for pharmacology are inadequate to cover all the competencies. Seventy-eight (85.7%) felt that the implementation of CBME curriculum for the 2019–20 batch MBBS students was impacted by COVID-19 pandemic. Conclusion: Although faculty development programs played a crucial role in sensitizing faculties to implement CBME curriculum, subject specific problems do persist and the faculties need to motivate themselves to suggest ways to resolve them.","PeriodicalId":18969,"journal":{"name":"National Journal of Physiology, Pharmacy and Pharmacology","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74132540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How effective are health awareness campaigns in India among young citizens? 印度年轻人的健康意识运动效果如何?

National Journal of Physiology, Pharmacy and Pharmacology Pub Date : 2023-01-01 DOI: 10.5455/njppp.2023.13.05272202317072023

Shibaji Gupta, A. Chakraborty, Rahul Biswas, B. Baur, R. Banerjee

{"title":"How effective are health awareness campaigns in India among young citizens?","authors":"Shibaji Gupta, A. Chakraborty, Rahul Biswas, B. Baur, R. Banerjee","doi":"10.5455/njppp.2023.13.05272202317072023","DOIUrl":"https://doi.org/10.5455/njppp.2023.13.05272202317072023","url":null,"abstract":"Background: COVID-resurgence has been seen of late in 2022. A country’s success against pandemics like COVID-19 depends largely on the health behavior of public, which is a function of health education. Aims and Objectives: To assess the effectiveness of such health campaigns that raises this vital awareness among undergraduate students. Materials and Methods: A web-based questionnaire was circulated among non-medical students and student groups of colleges based in Kolkata city (India), to assess their preparedness through their awareness and preventive practice adopted against COVID-19. Results: Mass media (85.3%) and social media (83.2%) were important sources of vital information. Fever (96.0%) was the most common symptom known, 95.9% aware about human-to-human transmission. 59.4% knew face masks were protective, while 40.2% held a 6-feet social distancing was effective. 82.2% said handwashing for 20 s or more with soap and 86.2% held that hand-rubs with 70% alcohol were helpful in disease prevention. 23.9% resorted to over-the-counter medications to prevent the disease, 43.2% used the Government’s “Aarogya Setu” mobile application. Participants from urban areas, higher socio-economic class, with elderly family member and who personally knew COVID-19 patient(s), tended to have adequate knowledge about the disease. However, many were not practicing adequate preventive measures. Conclusion: Although most were aware about COVID-19, knowledge about the correct application of preventive measures was lacking. Grassroots healthcare workers may be used in the sensitization process, along with mass awareness campaigns. Using the goodwill of political and religious leaders to inculcate protective habits in the general people should also be considered.","PeriodicalId":18969,"journal":{"name":"National Journal of Physiology, Pharmacy and Pharmacology","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79388859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Objective evaluation of thyroid function in postmenopausal women 目的评价绝经后妇女甲状腺功能

National Journal of Physiology, Pharmacy and Pharmacology Pub Date : 2023-01-01 DOI: 10.5455/njppp.2023.13.01033202330012023

Tahera Nazneen

{"title":"Objective evaluation of thyroid function in postmenopausal women","authors":"Tahera Nazneen","doi":"10.5455/njppp.2023.13.01033202330012023","DOIUrl":"https://doi.org/10.5455/njppp.2023.13.01033202330012023","url":null,"abstract":"Background: Thyroid dysfunction is more prevalent among elderly female. Assessment of thyroid dysfunction in the postmenopausal women is difficult due to their age, associated comorbidities, and ongoing treatment. Aims and Objectives: The aim of the study was to evaluate the thyroid status, presence of relative estrogen dominance and correlation of thyroid status with reproductive hormones in postmenopausal women. Materials and Methods: This cross-section study consists 40 postmenopausal women between age group 45 and 55 years. All participants were subjected to measure serum thyroid stimulating hormone (TSH) levels. Based on TSH levels, subjects were divided into normal thyroid function group (n = 12) and abnormal thyroid function group (n = 12). Serum was assayed for thyroxin binding globin (TBG), thyroid peroxidase antibody (TPO), estrogen, progesterone, and progesterone to estrogen ratio (P: E) in subjects of both the groups. Results: Around, 12 (30%) postmenopausal women had TSH values outside the range of 0.3–6.5 μIU/mL. TPO was positive only in one subject and 12.5% showed elevated TBG levels in abnormal thyroid group. Mean estrogen levels were significantly high, mean progesterone levels were significantly low and P: E was low in abnormal thyroid level group. A significant difference (P < 0.05) was observed on comparing the mean values of serum estrogen, progesterone, and P: E ratio among the groups. A significant positive correlation between TSH and serum estrogen, progesterone, and P: E and inverse correlation between estrogen and P: E was observed in abnormal thyroid level group. Conclusion: The thyroid dysfunction in postmenopausal women is associated with estrogen dominance. Therefore, menopausal women should be routinely screened for thyroid dysfunction, as part of their annual examination.","PeriodicalId":18969,"journal":{"name":"National Journal of Physiology, Pharmacy and Pharmacology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82152292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A randomized controlled study to evaluate and compare the effect of prednisolone, dexamethasone, and difluprednate eye drops on intraocular pressure in post-cataract surgery patients 一项评估和比较强的松龙、地塞米松和二氟泼尼酯滴眼液对白内障术后患者眼压影响的随机对照研究

National Journal of Physiology, Pharmacy and Pharmacology Pub Date : 2023-01-01 DOI: 10.5455/njppp.2023.13.03122202317042023

Apoorva M, K. J, Sushma K, N. R

{"title":"A randomized controlled study to evaluate and compare the effect of prednisolone, dexamethasone, and difluprednate eye drops on intraocular pressure in post-cataract surgery patients","authors":"Apoorva M, K. J, Sushma K, N. R","doi":"10.5455/njppp.2023.13.03122202317042023","DOIUrl":"https://doi.org/10.5455/njppp.2023.13.03122202317042023","url":null,"abstract":"Background: Topical corticosteroids are the effective anti-inflammatory agents prescribed following the cataract surgery. Their prolonged use can produce many side effects and one of them is steroid-induced glaucoma. Commonly used steroids in ocular therapy have tendency to cause rise in intraocular pressure (IOP). Elevated IOP if left untreated can ultimately progress to steroid-induced glaucoma. Any change in IOP should be monitored so that it can be detected and treated on time. Hence, the present study is planned. Aims and Objectives: The aims and objectives of the study are to evaluate and compare the effect of prednisolone, dexamethasone, and difluprednate eye drops on IOP in post-cataract surgery patients. Materials and Methods: A total of 90 patients were randomly allocated into three groups of thirty each receiving prednisolone, dexamethasone, and difluprednate eye drops, respectively, for 6 weeks in a tapering dose. Pre-operative and post-operative IOP measurements were noted and the patients were followed up for 1½ months. Results: Among 90 patients about 4.44% (n = 4) of them showed IOP elevation of ≥10 mmHg from baseline. About 14.44% (n = 13) patients showed moderate rise in IOP that is ≥5 mmHg. Clinically significant IOP elevation that is IOP increase of ≥10 mmHg and overall IOP of ≥21 mmHg was seen in 3.33% (n = 3) of the patients, and all of them belonged to difluprednate group. The mean post-operative IOP between the three treatment groups was not statistically significant. Conclusion: Difluprednate is having a higher potential of causing early and significant rise in IOP and hence has to be used judiciously with constant monitoring.","PeriodicalId":18969,"journal":{"name":"National Journal of Physiology, Pharmacy and Pharmacology","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79726660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0