Nanomaterials最新文献_第2页

Three-Dimensional Printed Nanocomposites with Tunable Piezoresistive Response. 具有可调压阻响应的三维印刷纳米复合材料

IF 4.4 3区材料科学

Nanomaterials Pub Date : 2024-11-02 DOI: 10.3390/nano14211761

Francesca Aliberti, Liberata Guadagno, Raffaele Longo, Marialuigia Raimondo, Roberto Pantani, Andrea Sorrentino, Michelina Catauro, Luigi Vertuccio

{"title":"Three-Dimensional Printed Nanocomposites with Tunable Piezoresistive Response.","authors":"Francesca Aliberti, Liberata Guadagno, Raffaele Longo, Marialuigia Raimondo, Roberto Pantani, Andrea Sorrentino, Michelina Catauro, Luigi Vertuccio","doi":"10.3390/nano14211761","DOIUrl":"10.3390/nano14211761","url":null,"abstract":"This study explores a novel approach to obtaining 3D printed strain sensors, focusing on how changing the printing conditions can produce a different piezoresistive response. Acrylonitrile butadiene styrene (ABS) filled with different weight concentrations of carbon nanotubes (CNTs) was printed in the form of dog bones via fused filament fabrication (FFF) using two different raster angles (0-90°). Scanning electron microscopy (SEM) and atomic force microscopy (AFM) in TUNA mode (TUNA-AFM) were used to study the morphological features and the electrical properties of the 3D printed samples. Tensile tests revealed that sensitivity, measured by the gauge factor (G.F.), decreased with increasing filler content for both raster angles. Notably, the 90° orientation consistently showed higher sensitivity than the 0° orientation for the same filler concentration. Creep and fatigue tests identified permanent damage through residual electrical resistance values. Additionally, a cross-shaped sensor was designed to measure two-dimensional deformations simultaneously, which is applicable in the robotic field. This sensor can monitor small and large deformations in perpendicular directions by tracking electrical resistance variations in its arms, significantly expanding its measuring range.","PeriodicalId":18966,"journal":{"name":"Nanomaterials","volume":"14 21","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11547783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Progress in Two-Dimensional Magnetic Materials. 二维磁性材料的最新进展。

IF 4.4 3区材料科学

Nanomaterials Pub Date : 2024-11-01 DOI: 10.3390/nano14211759

Guangchao Shi, Nan Huang, Jingyuan Qiao, Xuewen Zhang, Fulong Hu, Hanwei Hu, Xinyu Zhang, Jingzhi Shang

引用次数: 0

Liposomes and Their Therapeutic Applications in Enhancing Psoriasis and Breast Cancer Treatments. 脂质体及其在增强牛皮癣和乳腺癌治疗中的治疗应用。

IF 4.4 3区材料科学

Nanomaterials Pub Date : 2024-11-01 DOI: 10.3390/nano14211760

Amal Ali Elkordy, David Hill, Mohamed Attia, Cheng Shu Chaw

{"title":"Liposomes and Their Therapeutic Applications in Enhancing Psoriasis and Breast Cancer Treatments.","authors":"Amal Ali Elkordy, David Hill, Mohamed Attia, Cheng Shu Chaw","doi":"10.3390/nano14211760","DOIUrl":"10.3390/nano14211760","url":null,"abstract":"Psoriasis and breast cancer are two examples of diseases where associated inflammatory pathways within the body's immune system are implicated. Psoriasis is a complex, chronic and incurable inflammatory skin disorder that is primarily recognized by thick, scaly plaques on the skin. The most noticeable pathophysiological effect of psoriasis is the abnormal proliferation of keratinocytes. Breast cancer is currently the most diagnosed cancer and the leading cause of cancer-related death among women globally. While treatments targeting the primary tumor have significantly improved, preventing metastasis with systemic treatments is less effective. Nanocarriers such as liposomes and lipid nanoparticles have emerged as promising drug delivery systems for drug targeting and specificity. Advances in technologies and drug combinations have emerged to develop more efficient lipid nanocarriers to include more than one drug in combinational therapy to enhance treatment outcomes and/or relief symptoms for better patients' quality of life. Although there are FDA-approved liposomes with anti-cancer drugs for breast cancer, there are still unmet clinical needs to reduce the side effects associated with those nanomedicines. Hence, combinational nano-therapy may eliminate some of the issues and challenges. Furthermore, there are no nanomedicines yet clinically available for psoriasis. Hence, this review will focus on liposomes encapsulated single and/or combinational therapy to augment treatment outcomes with an emphasis on the effectiveness of combinational therapy within liposomal-based nanoparticulate drug delivery systems to tackle psoriasis and breast cancer. This review will also include an overview of both diseases, challenges in delivering drug therapy and the roles of nanomedicines as well as psoriasis and breast cancer models used for testing therapeutic interventions to pave the way for effective in vivo testing prior to the clinical trials.","PeriodicalId":18966,"journal":{"name":"Nanomaterials","volume":"14 21","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11547384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis of Composition-Tunable Ag-Cu Bimetallic Nanoparticles Through Plasma-Driven Solution Electrolysis. 通过等离子体驱动的溶液电解合成成分可调的银铜双金属纳米粒子。

IF 4.4 3区材料科学

Nanomaterials Pub Date : 2024-10-31 DOI: 10.3390/nano14211758

Chi Xu, Himashi P Andaraarachchi, Uwe R Kortshagen

引用次数: 0

Safety Evaluations of Rapamycin Perfluorocarbon Nanoparticles in Ovarian Tumor-Bearing Mice. 雷帕霉素全氟碳纳米粒子在卵巢肿瘤小鼠中的安全性评价

IF 4.4 3区材料科学

Nanomaterials Pub Date : 2024-10-31 DOI: 10.3390/nano14211752

Qingyu Zhou, John C Harding, Ping Fan, Ivan Spasojevic, Attila Kovacs, Antonina Akk, Adam Mitchell, Luke E Springer, Joseph P Gaut, Daniel A Rauch, Samuel A Wickline, Christine T N Pham, Katherine Fuh, Hua Pan

{"title":"Safety Evaluations of Rapamycin Perfluorocarbon Nanoparticles in Ovarian Tumor-Bearing Mice.","authors":"Qingyu Zhou, John C Harding, Ping Fan, Ivan Spasojevic, Attila Kovacs, Antonina Akk, Adam Mitchell, Luke E Springer, Joseph P Gaut, Daniel A Rauch, Samuel A Wickline, Christine T N Pham, Katherine Fuh, Hua Pan","doi":"10.3390/nano14211752","DOIUrl":"10.3390/nano14211752","url":null,"abstract":"Nanomedicine holds great potential for revolutionizing medical treatment. Ongoing research and advancements in nanotechnology are continuously expanding the possibilities, promising significant advancements in healthcare. To fully harness the potential of nanotechnology in medical applications, it is crucial to conduct safety evaluations for the nanomedicines that offer effective benefits in the preclinical stage. Our recent efficacy studies indicated that rapamycin perfluorocarbon (PFC) nanoparticles showed promise in mitigating cisplatin-induced acute kidney injury (AKI). As cisplatin is routinely administered to ovarian cancer patients as their first-line chemotherapy, in this study, we focused on evaluating the safety of rapamycin PFC nanoparticles in mice bearing ovarian tumor xenografts. Specifically, this study evaluated the effects of repeat-dose rapamycin PFC nanoparticle treatment on vital organs, the immune system, and tumor growth and assessed pharmacokinetics and biodistribution. Our results indicated that rapamycin PFC nanoparticle treatment did not cause any detectable adverse effects on cardiac, renal, or hepatic functions or on splenocyte populations, but it reduced the splenocyte secretion of IL-10, TNFα, and IL12p70 upon IgM stimulation. The pharmacokinetics and biodistribution results revealed a significant enhancement in the delivery of rapamycin to tumors by rapamycin PFC nanoparticles, which, in turn, led to a significant reduction in ovarian tumor growth. Therefore, rapamycin PFC nanoparticles have the potential to be clinically beneficial in cisplatin-treated ovarian cancer patients.","PeriodicalId":18966,"journal":{"name":"Nanomaterials","volume":"14 21","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11547995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of the Carrier Gas Flow in the CVD Synthesis of 2-Dimensional MoS₂ Based on the Spin-Coating of Liquid Molybdenum Precursors. 载气流量对基于液态钼前驱体自旋涂层的二维 MoS2 CVD 合成的影响。

IF 4.4 3区材料科学

Nanomaterials Pub Date : 2024-10-31 DOI: 10.3390/nano14211749

Fiorenza Esposito, Matteo Bosi, Giovanni Attolini, Francesca Rossi, Roberto Fornari, Filippo Fabbri, Luca Seravalli

{"title":"Influence of the Carrier Gas Flow in the CVD Synthesis of 2-Dimensional MoS2 Based on the Spin-Coating of Liquid Molybdenum Precursors.","authors":"Fiorenza Esposito, Matteo Bosi, Giovanni Attolini, Francesca Rossi, Roberto Fornari, Filippo Fabbri, Luca Seravalli","doi":"10.3390/nano14211749","DOIUrl":"10.3390/nano14211749","url":null,"abstract":"Atomically thin molybdenum disulfide (MoS2) is a two-dimensional semiconductor with versatile applications. The recent adoption of liquid molybdenum precursors in chemical vapor deposition has contributed significantly to the reproducible wafer-scale synthesis of MoS2 monolayer and few-layer films. In this work, we study the effects of the carrier gas flow rate on the properties of two-dimensional molybdenum disulfide grown by liquid-precursor-intermediate chemical vapor deposition on SiO2/Si substrates. We characterized the samples using Optical Microscopy, Scanning Electron Microscopy, Raman spectroscopy, and Photoluminescence spectroscopy. We analyzed samples grown with different nitrogen carrier flows, ranging from 150 to 300 sccm, and discussed the effect of carrier gas flows on their properties. We found a correlation between MoS2 flake lateral size, shape, and number of layers, and we present a qualitative growth model based on changes in sulfur provision caused by different carrier flows. We show how the use of liquid precursors can allow for the synthesis of homogeneous, single-layer flakes up to 100 µm in lateral size by optimizing the gas flow rate. These results are essential for gaining a deeper understanding of the growth process of MoS2.","PeriodicalId":18966,"journal":{"name":"Nanomaterials","volume":"14 21","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11547744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tuning the Electronic Bandgap of Penta-Graphene from Insulator to Metal Through Functionalization: A First-Principles Calculation. 通过功能化将五石墨烯的电子带隙从绝缘体调谐为金属：第一原理计算。

IF 4.4 3区材料科学

Nanomaterials Pub Date : 2024-10-31 DOI: 10.3390/nano14211751

J O Morales-Ferreiro, Gerardo Silva-Oelker, Chandra Kumar, Carlos Zambra, Zeyu Liu, Donovan E Diaz-Droguett, Diego Celentano

{"title":"Tuning the Electronic Bandgap of Penta-Graphene from Insulator to Metal Through Functionalization: A First-Principles Calculation.","authors":"J O Morales-Ferreiro, Gerardo Silva-Oelker, Chandra Kumar, Carlos Zambra, Zeyu Liu, Donovan E Diaz-Droguett, Diego Celentano","doi":"10.3390/nano14211751","DOIUrl":"10.3390/nano14211751","url":null,"abstract":"We performed first-principles density functional theory (DFT) calculations to numerically investigate the electronic band structures of penta-graphene (PG), a novel two-dimensional carbon material with a pentagonal lattice structure, and its chemically functionalized forms. Specifically, we studied hydrogenated PG (h-PG), fluorinated PG (f-PG), and chlorinated PG (Cl-PG). We used the generalized gradient approximation (GGA) and the hybrid Heyd-Scuseria-Ernzerhof (HSE06) exchange-correlation functional in the DFT-based software VASP to capture electronic properties accurately. Our results indicate that hydrogenation and fluorination increased the indirect bandgap of PG from 3.05 eV to 4.97 eV and 4.81 eV, respectively, thereby effectively transforming PG from a semiconductor to an insulator. In contrast, we found that chlorination closed the bandgap, thus indicating the metallic behavior of Cl-PG. These results highlight the feasibility of tuning the electronic properties of PG through functionalization, offering insight into designing new materials for nanoelectronic applications.","PeriodicalId":18966,"journal":{"name":"Nanomaterials","volume":"14 21","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11547250/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Blood Cell Membrane-Coated Nanomaterials as a Versatile Biomimetic Nanoplatform for Antitumor Applications. 血细胞膜包覆纳米材料作为抗肿瘤应用的多功能仿生纳米平台

IF 4.4 3区材料科学

Nanomaterials Pub Date : 2024-10-31 DOI: 10.3390/nano14211757

Hanchun Shen, Yongliang Ouyang, Liang Zhang, Jing Li, Shige Wang

{"title":"Blood Cell Membrane-Coated Nanomaterials as a Versatile Biomimetic Nanoplatform for Antitumor Applications.","authors":"Hanchun Shen, Yongliang Ouyang, Liang Zhang, Jing Li, Shige Wang","doi":"10.3390/nano14211757","DOIUrl":"10.3390/nano14211757","url":null,"abstract":"The application of nanomaterials in tumor therapy is increasingly widespread, offering more possibilities for enhanced tumor therapy. However, the unclear biological distribution and metabolism of nanomaterials may lead to immune rejection or inflammatory reactions, posing numerous challenges to their clinical translation. The rich diversity and multifaceted functions of blood cells offer promising biological avenues for enhancing the application of nanoparticles in cancer therapy. Blood cell membranes, being made of naturally found components in the body, exhibit significant biocompatibility, which can reduce the body's immune rejection response, extend the drug's residence time in the bloodstream, and enhance its bioavailability. Integrating blood cell membranes with nanomaterials enhances tumor therapy by improving targeted delivery, prolonging circulation time, and evading immune responses. This review summarizes recent advancements in the application of blood cell membrane-coated nanomaterials for antitumor therapy, with a particular focus on their use in photodynamic and photothermal treatments. Additionally, it explores their potential for synergistic effects when combined with other therapeutic modalities.","PeriodicalId":18966,"journal":{"name":"Nanomaterials","volume":"14 21","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11548044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thermal Stability and Purity of Graphene and Carbon Nanotubes: Key Parameters for Their Thermogravimetric Analysis (TGA). 石墨烯和碳纳米管的热稳定性和纯度：石墨烯和碳纳米管的热稳定性和纯度：热重分析 (TGA) 的关键参数。

IF 4.4 3区材料科学

Nanomaterials Pub Date : 2024-10-31 DOI: 10.3390/nano14211754

Markus Martincic, Stefania Sandoval, Judith Oró-Solé, Gerard Tobías-Rossell

{"title":"Thermal Stability and Purity of Graphene and Carbon Nanotubes: Key Parameters for Their Thermogravimetric Analysis (TGA).","authors":"Markus Martincic, Stefania Sandoval, Judith Oró-Solé, Gerard Tobías-Rossell","doi":"10.3390/nano14211754","DOIUrl":"10.3390/nano14211754","url":null,"abstract":"Thermal analysis is widely employed for the characterization of nanomaterials. It encompasses a variety of techniques that allow the evaluation of the physicochemical properties of a material by monitoring its response under controlled temperature. In the case of carbon nanomaterials, such as carbon nanotubes and graphene derivatives, thermogravimetric analysis (TGA) is particularly useful to determine the quality and stability of the sample, the presence of impurities and the degree of functionalization or doping after post-synthesis treatments. Furthermore, TGA is widely used to evaluate the thermal stability against oxidation by air, which can be, for instance, enhanced by the purification of the material and by nitrogen doping, finding application in areas where a retarded combustion of the material is required. Herein, we have evaluated key parameters that play a role in the data obtained from TGA, namely, gas flow rate, sample weight and temperature rate, used during the analysis. We found out that the heating rate played the major role in the process of combustion in the presence of air, inducing an increase in the temperature at which the oxidation of CNTs starts to occur, up to ca. 100 °C (from 1 °C min-1 to 50 °C min-1). The same trend was observed for all the evaluated systems, namely N-doped CNTs, graphene produced by mechanical exfoliation and N-doped reduced graphene samples. Other aspects, like the presence of impurities or structural defects in the evaluated samples, were analyzed by TGA, highlighting the versatility and usefulness of the technique to provide information of structural aspects and properties of carbon materials. Finally, a set of TGA parameters are recommended for the analysis of carbon nanomaterials to obtain reliable data.","PeriodicalId":18966,"journal":{"name":"Nanomaterials","volume":"14 21","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11547994/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of Microstructure and Physical Characteristics of Eco-Friendly Piezoelectric Composite Thin Films Based on Chitosan and Ln₂O₃-Doped Na_0.5Bi_0.5TiO₃-BaTiO₃ Nanoparticles. 基于壳聚糖和掺杂 Ln2O3 的 Na0.5Bi0.5TiO3-BaTiO3 纳米粒子的环保型压电复合薄膜的微观结构和物理特性研究

IF 4.4 3区材料科学

Nanomaterials Pub Date : 2024-10-31 DOI: 10.3390/nano14211755

Jacem Zidani, Moneim Zannen, Antonio Da Costa, Oumayma Mlida, Arash Jamali, Mustapha Majdoub, Mimoun El Marssi, Anthony Ferri, Abdelilah Lahmar

{"title":"Investigation of Microstructure and Physical Characteristics of Eco-Friendly Piezoelectric Composite Thin Films Based on Chitosan and Ln2O3-Doped Na0.5Bi0.5TiO3-BaTiO3 Nanoparticles.","authors":"Jacem Zidani, Moneim Zannen, Antonio Da Costa, Oumayma Mlida, Arash Jamali, Mustapha Majdoub, Mimoun El Marssi, Anthony Ferri, Abdelilah Lahmar","doi":"10.3390/nano14211755","DOIUrl":"10.3390/nano14211755","url":null,"abstract":"This paper investigates the synthesis and characterization of eco-friendly piezoelectric composite thin films composed of chitosan and Ln2O3-doped Na0.5Bi0.5TiO3-BaTiO3 (NBT-BT) nanoparticles. The films were fabricated using a solution-casting technique, successfully embedding the particles into the chitosan matrix, which resulted in enhanced piezoelectric properties compared to pure chitosan. Characterization methods, such as photoluminescence spectroscopy and piezo-response force microscopy (PFM) which revealed strong electromechanical responses, with notable improvements in piezoelectric performance due to the inclusion of NBT-BT nanoparticles. X-ray diffraction (XRD) analysis revealed a pure perovskite phase with the space group R3c for NBT-BT and NBT-BT-Ln particles. Scanning electron microscopy (SEM) images showed a non-uniform distribution of NBT-BT particles within the chitosan matrix. The results also suggest that the incorporation of rare earth elements further enhances the electrical and piezoelectric properties of the composites, highlighting their potential in flexible and smart device applications. Overall, these findings underscore the potential of chitosan-based composites in addressing environmental concerns while offering effective solutions for energy harvesting and biomedical applications.","PeriodicalId":18966,"journal":{"name":"Nanomaterials","volume":"14 21","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11547821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0