Netherlands Heart Journal最新文献

{"title":"Upper extremity versus lower extremity for secondary access during transcatheter aortic valve implantation: rationale and design of the randomised TAVI XS trial","authors":"Maxim J. P. Rooijakkers, Geert A. A. Versteeg, Kimberley I. Hemelrijk, Hugo M. Aarts, Daniël C. Overduin, Dirk-Jan van Ginkel, Pieter J. Vlaar, Marleen H. van Wely, Lokien X. van Nunen, Robert Jan van Geuns, Leen A. F. M. van Garsse, Guillaume S. C. Geuzebroek, Michel W. A. Verkroost, Laura Rodwell, Robin H. Heijmen, Pim A. L. Tonino, Jurrien M. ten Berg, Ronak Delewi, Niels van Royen","doi":"10.1007/s12471-024-01869-5","DOIUrl":"https://doi.org/10.1007/s12471-024-01869-5","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Background</h3><p>During transcatheter aortic valve implantation (TAVI), secondary access is required for angiographic guidance and temporary pacing. The most commonly used secondary access sites are the femoral artery (angiographic guidance) and the femoral vein (temporary pacing). An upper extremity approach using the radial artery and an upper arm vein instead of the lower extremity approach using the femoral artery and femoral vein may reduce clinically relevant secondary access site-related bleeding complications, but robust evidence is lacking.</p><h3 data-test=\"abstract-sub-heading\">Trial design</h3><p>The TAVI XS trial is a multicentre, randomised, open-label clinical trial with blinded evaluation of endpoints. A total of 238 patients undergoing transfemoral TAVI will be included. The primary endpoint is the incidence of clinically relevant bleeding (i.e. Bleeding Academic Research Consortium (BARC) type 2, 3 or 5 bleeding) of the randomised secondary access site (either diagnostic or pacemaker access, or both) within 30 days after TAVI. Secondary endpoints include time to mobilisation after TAVI, duration of hospitalisation, any BARC type 2, 3 or 5 bleeding, and early safety at 30 days according to Valve Academic Research Consortium‑3 criteria.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>The TAVI XS trial is the first randomised trial comparing an upper extremity approach to a lower extremity approach with regard to clinically relevant secondary access site-related bleeding complications. The results of this trial will provide important insights into the safety and efficacy of an upper extremity approach in patients undergoing transfemoral TAVI.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":"19 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140800509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Dutch Idiopathic Ventricular Fibrillation Registry: progress report on the quest to identify the unidentifiable","authors":"Lisa M. Verheul, Sanne A. Groeneveld, Job Stoks, Wiert F. Hoeksema, Matthijs J. M. Cluitmans, Pieter G. Postema, Arthur A. M. Wilde, Paul G. A. Volders, Rutger J. Hassink","doi":"10.1007/s12471-024-01870-y","DOIUrl":"https://doi.org/10.1007/s12471-024-01870-y","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Background</h3><p>Idiopathic ventricular fibrillation (iVF) is a rare cause of sudden cardiac arrest and, by definition, a diagnosis of exclusion. Due to the rarity of the disease, previous and current studies are limited by their retrospective design and small patient numbers. Even though the incidence of iVF has declined owing to the identification of new disease entities, an important subgroup of patients remains.</p><h3 data-test=\"abstract-sub-heading\">Aim</h3><p>To expand the existing Dutch iVF Registry into a large nationwide cohort of patients initially diagnosed with iVF, to reveal the underlying cause of iVF in these patients, and to improve arrhythmia management.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>The Dutch iVF Registry includes sudden cardiac arrest survivors with an initial diagnosis of iVF. Clinical data and outcomes are collected. Outcomes include subsequent detection of a diagnosis other than ‘idiopathic’, arrhythmia recurrence and death. Non-invasive electrocardiographic imaging is used to investigate electropathological substrates and triggers of VF.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>To date, 432 patients have been included in the registry (median age at event 40 years (interquartile range 28–52)), 61% male. During a median follow-up of 6 (2–12) years, 38 patients (9%) received a diagnosis other than ‘idiopathic’. Eleven iVF patients were characterised with electrocardiographic imaging.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>The Dutch iVF Registry is currently the largest of its kind worldwide. In this heterogeneous population of index patients, we aim to identify common functional denominators associated with iVF. With the implementation of non-invasive electrocardiographic imaging and other diagnostic modalities (e.g. echocardiographic deformation, cardiac magnetic resonance), we advance the possibilities to reveal pro-fibrillatory substrates.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":"120 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140800512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of ICD eligibility in non-ischaemic cardiomyopathy patients: a position statement by the Task Force of the Dutch Society of Cardiology","authors":"Anne-Lotte C. J. van der Lingen, Tom E. Verstraelen, Lieselot van Erven, Joan G. Meeder, Dominic A. Theuns, Kevin Vernooy, Arthur A. M. Wilde, Alexander H. Maass, Cornelis P. Allaart","doi":"10.1007/s12471-024-01859-7","DOIUrl":"https://doi.org/10.1007/s12471-024-01859-7","url":null,"abstract":"<p>International guidelines recommend implantation of an implantable cardioverter-defibrillator (ICD) in non-ischaemic cardiomyopathy (NICM) patients with a left ventricular ejection fraction (LVEF) below 35% despite optimal medical therapy and a life expectancy of more than 1 year with good functional status. We propose refinement of these recommendations in patients with NICM, with careful consideration of additional risk parameters for both arrhythmic and non-arrhythmic death. These additional parameters include late gadolinium enhancement on cardiac magnetic resonance imaging and genetic testing for high-risk genetic variants to further assess arrhythmic risk, and age, comorbidities and sex for assessment of non-arrhythmic mortality risk. Moreover, several risk modifiers should be taken into account, such as concomitant arrhythmias that may affect LVEF (atrial fibrillation, premature ventricular beats) and resynchronisation therapy. Even though currently no valid cut-off values have been established, the proposed approach provides a more careful consideration of risks that may result in withholding ICD implantation in patients with low arrhythmic risk and substantial non-arrhythmic mortality risk.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":"41 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140613898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design of the Dutch multicentre study on opportunistic screening of geriatric patients for atrial fibrillation using a smartphone PPG app: the Dutch-GERAF study","authors":"Lennaert A. R. Zwart, Jocelyn R. Spruit, Martin E. W. Hemels, Joris R. de Groot, Ron Pisters, Robert K. Riezebos, René W. M. M. Jansen","doi":"10.1007/s12471-024-01868-6","DOIUrl":"https://doi.org/10.1007/s12471-024-01868-6","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Background</h3><p>Screening of high-risk patients is advocated to achieve early detection and treatment of clinical atrial fibrillation (AF). The Dutch-GERAF study will address two major issues. Firstly, the effectiveness and feasibility of an opportunistic screening strategy for clinical AF will be assessed in frail older patients and, secondly, observational data will be gathered regarding the efficacy and safety of oral anticoagulation (OAC).</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>This is a multicentre study on opportunistic screening of geriatric patients for clinical AF using a smartphone photoplethysmography (PPG) application. Inclusion criteria are age ≥ 65 years and the ability to perform at least three PPG recordings within 6 months. Exclusion criteria are the presence of a cardiac implantable device, advanced dementia or a severe tremor. The PPG application records patients’ pulse at their fingertip and determines the likelihood of clinical AF. If clinical AF is suspected after a positive PPG recording, a confirmatory electrocardiogram is performed. Patients undergo a comprehensive geriatric assessment and a frailty index is calculated. Risk scores for major bleeding (MB) are applied. Standard laboratory testing and additional laboratory analyses are performed to determine the ABC-bleeding risk score. Follow-up data will be collected at 6 months, 12 months and 3 years on the incidence of AF, MB, hospitalisation, stroke, progression of cognitive disorders and mortality.</p><h3 data-test=\"abstract-sub-heading\">Discussion</h3><p>The Dutch-GERAF study will focus on frail older patients, who are underrepresented in randomised clinical trials. It will provide insight into the effectiveness of screening for clinical AF and the efficacy and safety of OAC in this high-risk population.</p><h3 data-test=\"abstract-sub-heading\">Trial registration</h3><p>NCT05337202.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":"14 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140573333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intramyocardial left anterior descending unroofing using a minimally invasive off-pump approach","authors":"Mara-Louise Wester, Annemiek M. J. De Vos, Peter Elsman, Joost Ter Woorst, Ferdi Akca","doi":"10.1007/s12471-024-01866-8","DOIUrl":"https://doi.org/10.1007/s12471-024-01866-8","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":"14 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140573210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unexpected gaps in knowledge of familial hypercholesterolaemia among Dutch general practitioners","authors":"Shirin Ibrahim, Jim N. de Goeij, Nick S. Nurmohamed, Jing Pang, Sibbeliene E. van den Bosch, Fabrice M. A. C. Martens, Jeanine E. Roeters van Lennep, Willemijn Corpeleijn, Talip Tumkaya, G. Kees Hovingh, Gerald F. Watts, Erik S. G. Stroes, Laurens F. Reeskamp","doi":"10.1007/s12471-024-01862-y","DOIUrl":"https://doi.org/10.1007/s12471-024-01862-y","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Background</h3><p>Familial hypercholesterolaemia (FH) warrants early diagnosis to prevent premature atherosclerotic cardiovascular disease (CVD). However, underdiagnosis and undertreatment of FH persist. This study aimed to assess the knowledge and practice of FH care among general practitioners (GPs) in the Netherlands.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>An internationally standardised, online questionnaire was sent to Dutch GPs between February 2021 and July 2022. The survey assessed knowledge and awareness of FH, encompassing general familiarity, awareness of management guidelines, inheritance, prevalence, CVD risk, and clinical practice related to FH. Comparative analysis was performed using data on primary care physicians from Western Australia, the Asia-Pacific region and the United Kingdom.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Of the 221 participating GPs, 62.4% rated their familiarity with FH as above average (score &gt; 4 on a 1–7 scale), with 91.4% considering themselves familiar with FH treatment and referral guidelines. Correct identification of the FH definition, typical lipid profile, inheritance pattern, prevalence and CVD risk was reported by 83.7%, 87.8%, 55.7%, 19.5%, and 13.6% of the respondents, respectively. Of the participants, 58.4% answered fewer than half of the 8 knowledge questions correctly. Dutch GPs reported greater FH familiarity and guideline awareness compared with their international counterparts but exhibited similar low performance on FH knowledge questions.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>Despite the Netherlands’ relatively high FH detection rate, substantial knowledge gaps regarding FH persist among Dutch GPs, mirroring global trends. Enhanced FH education and awareness in primary care are imperative to improve FH detection and ensure adequate treatment. Targeting the global suboptimal understanding of FH might require international efforts.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":"19 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140573213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous coronary intervention timing and coronary physiology in transcatheter aortic valve implantation patients.","authors":"Lennert Minten, Johan Bennett, Christophe Dubois","doi":"10.1007/s12471-024-01860-0","DOIUrl":"10.1007/s12471-024-01860-0","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"182"},"PeriodicalIF":2.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10951138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140028438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to 'Percutaneous coronary intervention timing and coronary physiology in transcatheter aortic valve implantation patients'.","authors":"Hugo M Aarts, Michiel Voskuil, Ronak Delewi","doi":"10.1007/s12471-024-01861-z","DOIUrl":"10.1007/s12471-024-01861-z","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"183"},"PeriodicalIF":2.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10951139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140049967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest: an overview of current practice and evidence.","authors":"Samir Ali, Christiaan L Meuwese, Xavier J R Moors, Dirk W Donker, Anina F van de Koolwijk, Marcel C G van de Poll, Diederik Gommers, Dinis Dos Reis Miranda","doi":"10.1007/s12471-023-01853-5","DOIUrl":"10.1007/s12471-023-01853-5","url":null,"abstract":"<p><p>Cardiac arrest (CA) is a common and potentially avoidable cause of death, while constituting a substantial public health burden. Although survival rates for out-of-hospital cardiac arrest (OHCA) have improved in recent decades, the prognosis for refractory OHCA remains poor. The use of veno-arterial extracorporeal membrane oxygenation during cardiopulmonary resuscitation (ECPR) is increasingly being considered to support rescue measures when conventional cardiopulmonary resuscitation (CPR) fails. ECPR enables immediate haemodynamic and respiratory stabilisation of patients with CA who are refractory to conventional CPR and thereby reduces the low-flow time, promoting favourable neurological outcomes. In the case of refractory OHCA, multiple studies have shown beneficial effects in specific patient categories. However, ECPR might be more effective if it is implemented in the pre-hospital setting to reduce the low-flow time, thereby limiting permanent brain damage. The ongoing ON-SCENE trial might provide a definitive answer regarding the effectiveness of ECPR. The aim of this narrative review is to present the most recent literature available on ECPR and its current developments.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"148-155"},"PeriodicalIF":2.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10951133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139906125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing dialogue: Introducing 'Letters to the Editor'.","authors":"Pim van der Harst","doi":"10.1007/s12471-024-01864-w","DOIUrl":"10.1007/s12471-024-01864-w","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":"32 4","pages":"147"},"PeriodicalIF":2.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10951177/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140175660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}