Veemal V Hemradj, Alexander J Spanjersberg, Marit Buitenhuis, Thanasie Markou, Rik S Hermanides, Jan-Henk Dambrink, Marcel Gosselink, Vincent Roolvink, Maarten van Leeuwen, Jan Paul Ottervanger
{"title":"Preoperative intra-aortic balloon pump in patients with ST-elevation myocardial infarction undergoing urgent cardiac bypass surgery.","authors":"Veemal V Hemradj, Alexander J Spanjersberg, Marit Buitenhuis, Thanasie Markou, Rik S Hermanides, Jan-Henk Dambrink, Marcel Gosselink, Vincent Roolvink, Maarten van Leeuwen, Jan Paul Ottervanger","doi":"10.1007/s12471-024-01879-3","DOIUrl":"10.1007/s12471-024-01879-3","url":null,"abstract":"<p><strong>Background: </strong>In patients with ST-elevation myocardial infarction (STEMI), either with or without cardiogenic shock, mechanical circulatory support with an intra-aortic balloon pump (IABP) is not associated with lower mortality. However, in STEMI patients undergoing urgent coronary artery bypass grafting (CABG), preoperative insertion of an IABP has been suggested to reduce mortality. In this study, the effect of preoperative IABP use on mortality in STEMI patients undergoing urgent CABG was investigated.</p><p><strong>Methods: </strong>All consecutive STEMI patients undergoing urgent CABG in a single centre between 2000 and 2018 were studied. The primary outcome, 30-day mortality, was compared between patients with and without a preoperative IABP. Subgroup analysis and multivariable analysis using a propensity score and inverse probability treatment weighting were performed to adjust for potential confounders.</p><p><strong>Results: </strong>A total of 246 patients were included, of whom 171 (69.5%) received a preoperative IABP (pIABP group) and 75 (30.5%) did not (non-pIABP group). In the pIABP group, more patients suffered from cardiogenic shock, persistent ischaemia and reduced left ventricular function. Unadjusted 30-day mortality was comparable between the pIABP and the non-pIABP group (13.3% vs 12.3%, p = 0.82). However, after correction for confounders and inverse probability treatment weighting preoperative IABP was associated with reduced 30-day mortality (relative risk 0.52, 95% confidence interval 0.30-0.88).</p><p><strong>Conclusion: </strong>In patients with STEMI undergoing urgent CABG, preoperative insertion of an IABP is associated with reduced mortality.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"276-282"},"PeriodicalIF":1.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11239630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A quest to unravel idiopathic ventricular fibrillation.","authors":"Joris R de Groot","doi":"10.1007/s12471-024-01874-8","DOIUrl":"10.1007/s12471-024-01874-8","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"226-227"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11143107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140857248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna van Veelen, Joëlle Elias, Pieter G Postema, Mariëlle C van de Veerdonk
{"title":"A bizarre electrocardiogram with a fruitful recovery.","authors":"Anna van Veelen, Joëlle Elias, Pieter G Postema, Mariëlle C van de Veerdonk","doi":"10.1007/s12471-024-01875-7","DOIUrl":"10.1007/s12471-024-01875-7","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"262-263"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11143082/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141088091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advancing cardiac care through national registries.","authors":"Pim van der Harst","doi":"10.1007/s12471-024-01878-4","DOIUrl":"10.1007/s12471-024-01878-4","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":"32 6","pages":"225"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11143101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141179378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna van Veelen, Joëlle Elias, Pieter G Postema, Mariëlle C van de Veerdonk
{"title":"A bizarre electrocardiogram with a fruitful recovery.","authors":"Anna van Veelen, Joëlle Elias, Pieter G Postema, Mariëlle C van de Veerdonk","doi":"10.1007/s12471-024-01876-6","DOIUrl":"10.1007/s12471-024-01876-6","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"264-266"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11143163/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jan-Willem Balder, Mariusz K Szymanski, Linda W van Laake, Pim van der Harst, Christiaan L Meuwese, Faiz Z Ramjankhan, Manon G van der Meer, Jeannine A J M Hermens, Michiel Voskuil, Eric E C de Waal, Dirk W Donker, Marish I F J Oerlemans, Adriaan O Kraaijeveld
{"title":"ECPELLA as a bridge-to-decision in refractory cardiogenic shock: a single-centre experience.","authors":"Jan-Willem Balder, Mariusz K Szymanski, Linda W van Laake, Pim van der Harst, Christiaan L Meuwese, Faiz Z Ramjankhan, Manon G van der Meer, Jeannine A J M Hermens, Michiel Voskuil, Eric E C de Waal, Dirk W Donker, Marish I F J Oerlemans, Adriaan O Kraaijeveld","doi":"10.1007/s12471-024-01872-w","DOIUrl":"10.1007/s12471-024-01872-w","url":null,"abstract":"<p><strong>Background: </strong>In refractory cardiogenic shock, temporary mechanical support (tMCS) may be crucial for maintaining tissue perfusion and oxygen delivery. tMCS can serve as a bridge-to-decision to assess eligibility for left ventricular assist device (LVAD) implantation or heart transplantation, or as a bridge-to-recovery. ECPELLA is a novel tMCS configuration combining venoarterial extracorporeal membrane oxygenation with Impella. The present study presents the clinical parameters, outcomes, and complications of patients supported with ECPELLA.</p><p><strong>Methods: </strong>All patients supported with ECPELLA at University Medical Centre Utrecht between December 2020 and August 2023 were included. The primary outcome was 30-day mortality, and secondary outcomes were LVAD implantation/heart transplantation and safety outcomes.</p><p><strong>Results: </strong>Twenty patients with an average age of 51 years, and of whom 70% were males, were included. Causes of cardiogenic shock were acute heart failure (due to acute coronary syndrome, myocarditis, or after cardiac surgery) or chronic heart failure, respectively 70 and 30% of cases. The median duration of ECPELLA support was 164 h (interquartile range 98-210). In 50% of cases, a permanent LVAD was implanted. Cardiac recovery within 30 days was seen in 30% of cases and 30-day mortality rate was 20%. ECPELLA support was associated with major bleeding (40%), haemolysis (25%), vascular complications (30%), kidney failure requiring replacement therapy (50%), and Impella failure requiring extraction (15%).</p><p><strong>Conclusion: </strong>ECPELLA can be successfully used as a bridge to LVAD implantation or as a bridge-to-recovery in patients with refractory cardiogenic shock. Despite a significant number of complications, 30-day mortality was lower than observed in previous cohorts.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"245-253"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11143097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140863710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eline H Ploumen, Edimir Semedo, Carine J M Doggen, Carl E Schotborgh, Rutger L Anthonio, Peter W Danse, Edouard Benit, Adel Aminian, Martin G Stoel, Marc Hartmann, K Gert van Houwelingen, Martijn Scholte, Ariel Roguin, Gerard C M Linssen, Paolo Zocca, Clemens von Birgelen
{"title":"Ethnic minorities treated with new-generation drug-eluting coronary stents in two European randomised clinical trials.","authors":"Eline H Ploumen, Edimir Semedo, Carine J M Doggen, Carl E Schotborgh, Rutger L Anthonio, Peter W Danse, Edouard Benit, Adel Aminian, Martin G Stoel, Marc Hartmann, K Gert van Houwelingen, Martijn Scholte, Ariel Roguin, Gerard C M Linssen, Paolo Zocca, Clemens von Birgelen","doi":"10.1007/s12471-024-01873-9","DOIUrl":"10.1007/s12471-024-01873-9","url":null,"abstract":"<p><strong>Background: </strong>Several ethnic minorities have an increased risk of cardiovascular events, but previous European trials that investigated clinical outcome after coronary stenting did not assess the patients' ethnic background.</p><p><strong>Aims: </strong>To compare ethnic minority and Western European trial participants in terms of both cardiovascular risk profile and 1‑year clinical outcome after percutaneous coronary intervention.</p><p><strong>Methods: </strong>In the BIO-RESORT and BIONYX randomised trials, which assessed new-generation drug-eluting stents, information on patients' self-reported ethnic background was prospectively collected. Pooled patient-level data of 5803 patients, enrolled in the Netherlands and Belgium, were analysed in this prespecified analysis. The main endpoint was target vessel failure after 1 year.</p><p><strong>Results: </strong>Patients were classified as belonging to an ethnic minority (n = 293, 5%) or of Western European origin (n = 5510, 95%). Follow-up data were available in 5772 of 5803 (99.5%) patients. Ethnic minority patients were younger, less often female, more often current smokers, more often medically treated for diabetes, and more often had a positive family history of coronary artery disease. The main endpoint target vessel failure did not differ between ethnic minority and Western European patients (3.5% vs 4.9%, hazard ratio 0.71, 95% confidence interval 0.38-1.33; p = 0.28). There was also no difference in mortality, myocardial infarction, and repeat revascularisation rates.</p><p><strong>Conclusions: </strong>Despite the unfavourable cardiovascular risk profile of ethnic minority patients, short-term clinical outcome after treatment with contemporary drug-eluting stents was highly similar to that in Western European patients. Further efforts should be made to ensure the enrolment of more ethnic minority patients in future coronary stent trials.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"254-261"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11143136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141076265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lineke Derks, Niki M Medendorp, Saskia Houterman, Victor A W M Umans, Jos G Maessen, Dennis van Veghel
{"title":"Building a patient-centred nationwide integrated cardiac care registry: intermediate results from the Netherlands.","authors":"Lineke Derks, Niki M Medendorp, Saskia Houterman, Victor A W M Umans, Jos G Maessen, Dennis van Veghel","doi":"10.1007/s12471-024-01877-5","DOIUrl":"10.1007/s12471-024-01877-5","url":null,"abstract":"<p><p>This paper presents an overview of the development of an integrated patient-centred cardiac care registry spanning the initial 5 years (September 2017 to December 2022). The Netherlands Heart Registration facilitates registration committees in which mandated cardiologists and cardiothoracic surgeons structurally evaluate quality of care using real-world data. With consistent attendance rates exceeding 60%, a valuable network is supported. Over time, the completeness level of the registry has increased. Presently, four out of six quality registries show over 95% completeness in variables that are part of the quality policies of cardiology and cardiothoracic surgery societies. Notably, 93% of the centres voluntarily report outcomes related to open heart surgery and (trans)catheter interventions publicly. Moreover, outcomes after implantable cardioverter-defibrillator and pacemaker procedures are transparently reported by 26 centres. Multiple innovation projects have been initiated by the committees, signalling a shift from publishing outcomes transparently to collaborative efforts in sharing healthcare processes and investigating improvement initiatives. The next steps will focus on the entire pathway of cardiac care for a specific medical condition instead of focusing solely on the outcomes of the procedures. This redirection of focus to a comprehensive assessment of the patient pathway in cardiac care ultimately aims to optimise outcomes for all patients.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"228-237"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11143093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141076264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Overcoming therapeutic inertia in LDL cholesterol-lowering treatment with education and simplified treatment algorithms.","authors":"Maarten J G Leening","doi":"10.1007/s12471-024-01863-x","DOIUrl":"10.1007/s12471-024-01863-x","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"198-199"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11039431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140184998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}