Ivo M van Dongen, Jobst Winter, Bart Aben, Gilbert W M Wijntjens, Ronak Delewi, Jan Siebers, Robin N Kok, Frederieke G Schaafsma
{"title":"Cardiovascular disease and absenteeism in Dutch occupational health: a retrospective study in a regular working population.","authors":"Ivo M van Dongen, Jobst Winter, Bart Aben, Gilbert W M Wijntjens, Ronak Delewi, Jan Siebers, Robin N Kok, Frederieke G Schaafsma","doi":"10.1007/s12471-025-01989-6","DOIUrl":"10.1007/s12471-025-01989-6","url":null,"abstract":"<p><strong>Background: </strong>There is very limited data available on the impact of cardiovascular disease (CVD) on absenteeism occurrence, absenteeism duration, and the associated rough cost-estimate for employers.</p><p><strong>Methods: </strong>We extracted routinely collected absenteeism data for the years 2019-2022 from a database maintained by two large, nationally operating occupational health services (n = 443,740). All diagnoses and included sickness cases were recorded > 6 weeks of absenteeism. Descriptive statistics, including median values (IQR) and percentages, were calculated and compared using the Mann-Whitney U test and Pearson chi-square test. Subgroup comparisons were performed using the Kruskal-Wallis test. To analyse return-to-work over time, a Kaplan-Meier curve was constructed, and differences in return-to-work were assessed using the Log Rank (Mantel-Cox) test.</p><p><strong>Results: </strong>CVD is the primary cause of absenteeism in 3.2% of all absenteeism cases. The median duration of absenteeism following CVD was 119 working days (IQR 156; Q1-Q3 62.9-218.6) with a minimum rough cost-estimate to employers of € 37,000 per employee. The most frequently occurring CVD diagnoses were: acute myocardial infarction, cerebrovascular disease, cardiac arrhythmia, unspecified cardiovascular complaints and angina.</p><p><strong>Conclusions: </strong>CVD occurs frequently, results in prolonged absenteeism, and incurs high costs for employers. We strongly believe that CVD-related absenteeism should receive greater attention. Specifically, both in-hospital and outpatient treatments should place a stronger emphasis on work-related issues, including strategies for returning to work with or without tailored assignments in the workplace. This focus will help ensure that employees can sustainably return to work and continue to contribute to society.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"343-353"},"PeriodicalIF":2.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12550078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diekje R Schouten, Josianne H Heuver, Wendy Stouten-Gresnigt, Paulien Weijers, Esther van der Perk, Michiel Soullié, Joyce Peper, Benno J M W Rensing, Jurriën M Ten Berg, Uday Sonker, Martin J Swaans, Leo Timmers
{"title":"Next-day discharge after transcatheter aortic valve replacement in a Dutch hospital.","authors":"Diekje R Schouten, Josianne H Heuver, Wendy Stouten-Gresnigt, Paulien Weijers, Esther van der Perk, Michiel Soullié, Joyce Peper, Benno J M W Rensing, Jurriën M Ten Berg, Uday Sonker, Martin J Swaans, Leo Timmers","doi":"10.1007/s12471-025-01986-9","DOIUrl":"10.1007/s12471-025-01986-9","url":null,"abstract":"<p><strong>Background: </strong>In recent years, hospital stays after transcatheter aortic valve replacement (TAVR) have shortened. Previous studies have shown that next-day discharge (NDD) is feasible without compromising patient safety, but data from the Dutch hospital setting are lacking. To assess the real-world effect of a NDD policy after TAVR.</p><p><strong>Methods: </strong>A next-day discharge policy was introduced in 2022 at St. Antonius Hospital Nieuwegein, the Netherlands. We included elective TAVR patients between August 2022 and August 2024, excluding those with pre-existing hospitalisation, transapical access, or intraprocedural mortality.</p><p><strong>Results: </strong>Among 460 patients (mean age 80.1 ± 6.2 years, 40.9% female, and a median Edmonton Frail score of 3.0 [1.0-4.0]), the majority underwent transfemoral TAVR (99.1%), under local anaesthesia (97.0%), using self-expanding valves (78.3%). Patients in the NDD group were more often male, less frail, and less likely to have right bundle branch block before TAVR compared to delayed discharge (DD) patients. NDD was feasible in 269 patients (58.5%) with a low number of post-discharge complications at 30 days: 1.9% permanent pacemaker implantation and 2.2% minor vascular complications. There were no cases of mortality, major vascular complications, or in-hospital stroke. Main reasons for DD were conduction disorders, access site complications, and stroke, which contributed to a higher incidence of complications in the DD group (18.3% permanent pacemaker implantation, p < 0.001, 3.1% stroke, p = 0.004, 1.6% major vascular complication, overall p-value 0.02).</p><p><strong>Conclusion: </strong>After implementing an NDD policy, 58.5% of patients were eligible for NDD after TAVR with a very low post-discharge complication rate.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"354-360"},"PeriodicalIF":2.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12549464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yvemarie B O Somsen, Rohan S Mansaram, Roel Hoek, Camila S Pizarro Perez, Dicky K Y Yee, Stefan P Schumacher, Wynand J Stuijfzand, Jos W R Twisk, Bimmer E P M Claessen, Niels J Verouden, Ruben W de Winter, Sebastiaan A Kleijn, José P Henriques, Alexander Nap, Paul Knaapen
{"title":"Longitudinal results from a dedicated chronic total coronary occlusions percutaneous coronary intervention program-a single-center experience.","authors":"Yvemarie B O Somsen, Rohan S Mansaram, Roel Hoek, Camila S Pizarro Perez, Dicky K Y Yee, Stefan P Schumacher, Wynand J Stuijfzand, Jos W R Twisk, Bimmer E P M Claessen, Niels J Verouden, Ruben W de Winter, Sebastiaan A Kleijn, José P Henriques, Alexander Nap, Paul Knaapen","doi":"10.1007/s12471-025-01988-7","DOIUrl":"10.1007/s12471-025-01988-7","url":null,"abstract":"<p><strong>Objective: </strong>To provide insight into the longitudinal (> 10 years) results of a dedicated CTO PCI program in a single center.</p><p><strong>Background: </strong>Percutaneous coronary intervention (PCI) of chronic total occlusions (CTO) requires substantial operator experience. Dedicated CTO programs aim to increase technical success rates through sufficient case volume. However, longitudinal data beyond 10 years on such programs are scarce.</p><p><strong>Methods: </strong>We included 1185 patients who underwent CTO PCI in the Amsterdam University Medical Center between 2013 and 2024. Technical CTO PCI success was defined as thrombolysis in myocardial infarction flow grade 3 and < 30% residual stenosis. Procedural success was defined as technical success in the absence of in-hospital major adverse cardiovascular events. Multivariable logistic regression analyses were used to identify predictors for technical success.</p><p><strong>Results: </strong>Mean age was 66 ± 11 years; 81% were male. Overall technical CTO PCI success (92%) and procedural success (87%) rates were high and consistent. We observed temporal changes in wire crossing time (31 [7-56] to 23 [5-67] minutes), contrast volume (360 ± 160 to 210 ± 101 mL), and procedural time (90 [60-130] to 121 [80-165] minutes). Additionally, MACE rate improved from 13% (in 2013-2015) to 7% (in 2021-2024). Age ≥ 65 years, prior CABG, three-vessel disease, and an intermediate to high J‑CTO score (≥ 2) predicted technical failure.</p><p><strong>Conclusions: </strong>This study reports the longitudinal (> 10 years) results of a dedicated CTO PCI program, which confirms that high technical CTO PCI and procedural success rates can be achieved by a single center.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"361-369"},"PeriodicalIF":2.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12549449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145251944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Innovation, implementation, and insight: new contributions to Dutch cardiovascular care.","authors":"Pim van der Harst","doi":"10.1007/s12471-025-01990-z","DOIUrl":"10.1007/s12471-025-01990-z","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"289"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12454738/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144992919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maikel H M Immens, Lars S Witte, Abdelhak El Bouziani, Anthonie Duijnhouwer, Berto J Bouma, Jan G P Tijssen, Frank-Erik de Leeuw, Rob J de Winter, Tim J F Ten Cate
{"title":"Anatomical features of percutaneously closed patent foramen ovale in patients with cryptogenic stroke.","authors":"Maikel H M Immens, Lars S Witte, Abdelhak El Bouziani, Anthonie Duijnhouwer, Berto J Bouma, Jan G P Tijssen, Frank-Erik de Leeuw, Rob J de Winter, Tim J F Ten Cate","doi":"10.1007/s12471-025-01983-y","DOIUrl":"10.1007/s12471-025-01983-y","url":null,"abstract":"<p><strong>Background: </strong>Patent foramen ovale (PFO) is increasingly recognized as a cause of stroke, with a prevalence of approximately 25% in the general population. Consequently, the likelihood of encountering a 'bystander PFO' in young patients who have experienced a stroke seems significant. To aid in identifying patients with a PFO-related cryptogenic stroke, an interdisciplinary Heart-Stroke Team (HST) has been established. This team evaluates patients who have suffered from stroke and were diagnosed with a PFO to assess its potential contribution. Understanding the anatomical features of PFOs associated with stroke is essential for decision-making. This study examines the PFO characteristics of all patients who underwent percutaneous PFO closure for cryptogenic stroke at two congenital heart disease institutions in the Netherlands.</p><p><strong>Methods: </strong>Data on all patients who underwent PFO closure from 2016 to 2022 were collected. Anatomical characteristics were measured using transesophageal echocardiography and analyzed by two cardiologists.</p><p><strong>Results: </strong>In total, 223 patients underwent PFO closure. The mean age was 42.8 ± 10.7 years, with 115 (51.6%) being male. Approximately 80% of all patients had at least one risk-enhancing PFO feature (moderate to severe shunt and/or atrial septal aneurysm of > 10 mm).</p><p><strong>Conclusion: </strong>Although all patients accepted for percutaneous PFO closure were individually assessed by a dedicated HST, 20% had a PFO without risk-enhancing features but were still accepted for closure due to other reasons. This highlights the importance of careful individual assessment of young stroke patients with a PFO. Future studies are needed to identify the characteristics that contribute to stroke in these patients.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"313-318"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12454762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Platypnea-Orthodeoxia: A case of PFO with aortic compression.","authors":"Joana Guimarães, Patrícia Costa, Joana Ferreira","doi":"10.1007/s12471-025-01943-6","DOIUrl":"10.1007/s12471-025-01943-6","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"323-324"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12454843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}