Netherlands Heart Journal最新文献

{"title":"PRACTICE-HF: Implementation of an updated clinical protocol for acute heart failure.","authors":"Lukas Peeters, Mick Hoen, Delian Hofman, Bjorn Hompes, Bart Langenveld, Danae Smeets, Timo Lenderink, Hans Peter Brunner-La Rocca, Sandra Sanders-van Wijk","doi":"10.1007/s12471-025-02004-8","DOIUrl":"10.1007/s12471-025-02004-8","url":null,"abstract":"<p><strong>Background: </strong>Despite recent advances in the treatment of acute heart failure (AHF), implementation of new evidence into clinical practice remains challenging.</p><p><strong>Methods: </strong>We conducted a single-center descriptive exploratory study within an ongoing prospective AHF registry. Adult patients admitted with AHF, without requiring intensive care, were included consecutively. An updated local AHF protocol was developed and implemented by group-education sessions, pocket cards, and posters. Patients before (control group) and after (intervention group) implementation of the new protocol were compared in terms of compliance to the protocol and 90-day outcomes-blanking the implementation period. Subgroups entailed HF with (mildly) reduced and preserved ejection fraction.</p><p><strong>Results: </strong>Patients were elderly, with almost half being de novo HF patients. Groups were comparable except for higher NT-proBNP in the implementation group and a higher cancer prevalence in the control group. The intervention group showed an increase in in-hospital use of acetazolamide (59.8 vs 0%, p < 0.001), in iron deficiency testing and correct iv. iron administration (42.9% vs 78.6% p ≤ 0.001). Pre-discharge installation of SGLT2 inhibitors showed a positive trend (44.2 vs 20% in HF(m)rEF patients and 29.4 vs 4% in HFpEF, both p = 0.01) HF-event-free survival at 90 days numerically favored the intervention group (29.9 vs 44.3%, p = 0.054), whereas length of hospital stay increased by 1 day (p = 0.011).</p><p><strong>Conclusion: </strong>Implementing a local updated AHF protocol improved adoption of several evidence based AHF interventions. This may translate into improved patient outcomes, against a minor increase in hospital duration.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"46-53"},"PeriodicalIF":2.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12852520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A stitch in the left main artery.","authors":"Yehia Saleh, Saul Rios, Hussein Shaqra","doi":"10.1007/s12471-025-01950-7","DOIUrl":"10.1007/s12471-025-01950-7","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"81-82"},"PeriodicalIF":2.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12852530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to: 'Persistent high major adverse cardiac outcome of 7% with chronic total occlusion intervention in patients with stable coronary artery disease'.","authors":"Yvemarie B O Somsen","doi":"10.1007/s12471-026-02018-w","DOIUrl":"10.1007/s12471-026-02018-w","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"86"},"PeriodicalIF":2.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12852509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146030406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of follow-up care for patients presenting with non-typical chest pain at the emergency department.","authors":"Leonard Voorhout, Mieneke Willems, Frank Willems, Sanne Heijmans, Jelle Luijten, Martin Hemels, Ron Pisters","doi":"10.1007/s12471-025-02009-3","DOIUrl":"10.1007/s12471-025-02009-3","url":null,"abstract":"<p><strong>Background: </strong>Failure to identify the underlying cause of chest pain in patients presenting to the cardiac emergency department (ED) poses a significant health and economic challenge. Non-typical chest pain in patients without a history of cardiovascular disease often leads to uncertainty regarding appropriate follow-up care.</p><p><strong>Research question: </strong>Does outpatient follow-up consultation with a cardiologist impact recurrent cardiac ED visits and major adverse cardiac and cerebrovascular events (MACCE) in patients with non-typical chest pain and no prior cardiovascular history?</p><p><strong>Study design and methods: </strong>This retrospective cohort study included 429 patients presenting to the cardiac ED with non-typical chest pain and no history of cardiovascular disease. Of these, 213 patients (49.7%) received follow-up consultations with a cardiologist within three months of their index ED visit. We compared rates of recurrent (cardiac) ED visits, MACCE, and healthcare resource utilization during a one-year follow-up between patients who received follow-up consultations and those who did not.</p><p><strong>Results: </strong>Patients with follow-up consultations had a significantly higher rate of revisits to the cardiac ED (13.6% vs. 5.1%) during the one-year follow-up period. There was no significant difference in MACCE between the two groups. Additionally, follow-up consultations were associated with an increase in healthcare resource utilization, including specialized cardiac tests.</p><p><strong>Conclusion: </strong>This study highlights the potential drawbacks of routine follow-up consultations in this patient population and calls for further prospective research to validate these findings.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"54-59"},"PeriodicalIF":2.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12852522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Persistent high major adverse cardiac outcome of 7% with chronic total occlusion intervention in patients with stable coronary artery disease.","authors":"Mohammad Reza Movahed","doi":"10.1007/s12471-026-02017-x","DOIUrl":"10.1007/s12471-026-02017-x","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"85"},"PeriodicalIF":2.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12852512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146019114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of life before and after catheter ablation (pulmonary vein isolation) for atrial fibrillation: Results from the Netherlands Heart Registration.","authors":"Tom Oirbans, Jonas S S G de Jong, Gijs J van Steenbergen, Ahmet Adiyaman, Bas A Schoonderwoerd, Hilda G Rijnhart-de Jong, Pepijn H van der Voort, Justin G L M Luermans, Sjoerd W Westra, Wichert J Kuijt, Michelle D van der Stoel, Johannes C Kelder, Lucas V A Boersma, Jippe C Balt","doi":"10.1007/s12471-025-02014-6","DOIUrl":"10.1007/s12471-025-02014-6","url":null,"abstract":"<p><strong>Background: </strong>Reducing AF-related symptoms and improving health-related quality of life (HRQoL) are important drivers in the decision for pulmonary vein isolation (PVI) in treating symptomatic atrial fibrillation (AF). We assessed the association between various patient characteristics, intervention, and outcome variables, and HRQoL both prior to and one year after PVI, with specific attention to groups that did not improve or were still impaired in HRQoL post PVI.</p><p><strong>Methods: </strong>Observational, retrospective multicenter cohort study within 8 hospitals participating in the Netherlands Heart Registration (NHR). Patients who underwent PVI between 2016 and 2019 and completed the Atrial Fibrillation Effect on Quality-of-Life (AFEQT) questionnaire both prior to and one year after were included. Accepted cut-off values for impaired HRQoL and clinically important difference (CID) were used.</p><p><strong>Results: </strong>Mean AFEQT score (n = 2,534) was 55.6 ± 19.7 prior to intervention and 79.8 ± 20.2 after. Post-PVI, 39.5% of the population was still impaired in HRQoL (< 80 points), and 19.2% failed to achieve CID (delta ≥ 5 points). Lower baseline AFEQT-score (odds ratio [OR], 0.96 [per 1‑point increase]; 95% CI, 0.96-0.97; p < 0.001) and female sex (odds ratio [OR], 1.42; 95% CI, 1.16-1.75; p < 0.001) were the most prominent related factors with impaired HRQoL post-PVI. Higher baseline AFEQT-score (odds ratio [OR], 1.04 [per 1‑point increase]; 95% CI, 1.04-1.05; p < 0.001) was strongly associated with failure to achieve CID.</p><p><strong>Conclusion: </strong>Despite a major increase in HRQoL across the population, over one-third of patients were still impaired in HRQoL post-PVI. Multiple factors were identified that may guide counselling of AF patients about treatment choice.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"72-79"},"PeriodicalIF":2.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12852550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145998524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An ominous ECG.","authors":"M Libbrecht, T De Meyer, M Boulaksil","doi":"10.1007/s12471-025-02007-5","DOIUrl":"10.1007/s12471-025-02007-5","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"80"},"PeriodicalIF":2.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12852521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145763280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An ominous ECG.","authors":"M Libbrecht, T De Meyer, M Boulaksil","doi":"10.1007/s12471-025-02008-4","DOIUrl":"10.1007/s12471-025-02008-4","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"83-84"},"PeriodicalIF":2.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12852557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145763317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"More than numbers: survival, symptoms, and what care triggers.","authors":"Pim van der Harst","doi":"10.1007/s12471-026-02024-y","DOIUrl":"10.1007/s12471-026-02024-y","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"45"},"PeriodicalIF":2.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12852545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146011450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mortality rates and causes of death after cardiac interventions: real-world short- and long-term insights from the Netherlands.","authors":"Lineke Derks, Maaike M Roefs, Gijs J van Steenbergen, Saskia Houterman, Dennis van Veghel","doi":"10.1007/s12471-025-02016-4","DOIUrl":"10.1007/s12471-025-02016-4","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to gain insight into mortality rates and causes of death after major cardiac interventions, using nationwide real-world data from the Netherlands.</p><p><strong>Methods: </strong>For this retrospective observational study, data from Statistics Netherlands and the Dutch all-payer claims database in the period 2016-2019 were used to select the intervention groups: coronary artery bypass grafting (CABG), percutaneous coronary intervention, surgical aortic valve replacement (SAVR), SAVR + CABG, mitral valve surgery, transcatheter heart valve intervention, pulmonary vein isolation and minimally-invasive maze surgery. For all interventions, survival status, date, and cause of death were retrieved. Causes of death were clustered for cardiovascular (CV) and non-CV causes by their corresponding ICD-10 code at different time intervals up to 5 years after the intervention.</p><p><strong>Results: </strong>A total of 203,001 interventions were included, and 13.7% (27,832) of the patients died during the 5‑year follow-up. Of these, 45.1% (12,560) were CV, and 54.9% (15,272) were non-CV deaths. After coronary revascularization, valve intervention, and aortic valve intervention and coronary revascularization combined, respectively, non-CV mortality increased from 14.2%, 12.9% and 20.7% at 30 days to 44.5%, 47.0% and 44.5% after 2 years. Of all deaths up to 5 years, 54.7%, 54.3% and 55.3% were non-CV.</p><p><strong>Conclusion: </strong>Initially main cause of death after cardiac intervention is CV-related. The proportion of non-CV deaths increases during follow-up, impacting survival for all patients up to 5 years after intervention. (Fig. 1).</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"60-71"},"PeriodicalIF":2.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12852519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146011485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}