Percutaneous left stellate ganglion block for refractory ventricular tachycardia in structural heart disease: our single-centre experience.

IF 1.7 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Netherlands Heart Journal Pub Date : 2024-08-01 Epub Date: 2024-06-12 DOI:10.1007/s12471-024-01880-w
Vincent R van der Pas, Jurren M van Opstal, Marcoen F Scholten, Nelson P Monteiro de Oliveira, Ron G H Speekenbrink, Pascal F H M van Dessel
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引用次数: 0

Abstract

Introduction: When electrical storm (ES) is amenable to neither antiarrhythmic drugs, nor deep sedation or catheter ablation, autonomic modulation may be considered. We report our experience with percutaneous left stellate ganglion block (PSGB) to temporarily suppress refractory ventricular arrhythmia (VA) in patients with structural heart disease.

Methods: A retrospective analysis was performed at our institution of patients with structural heart disease and an implantable cardioverter defibrillator (ICD) who had undergone PSGB for refractory VA between January 2018 and October 2021. The number of times antitachycardia pacing (ATP) was delivered and the number of ICD shocks/external cardioversions performed in the week before and after PSGB were evaluated. Charts were checked for potential complications.

Results: Twelve patients were identified who underwent a combined total of 15 PSGB and 5 surgical left cardiac sympathetic denervation procedures. Mean age was 73 ± 5.8 years and all patients were male. Nine of 12 (75%) had ischaemic cardiomyopathy, with the remainder having non-ischaemic dilated cardiomyopathy. Mean left ventricular ejection fraction was 35% (± 12.2%). Eight of 12 (66.7%) patients were already being treated with both amiodarone and beta-blockers. The reduction in ATP did not reach statistical significance (p = 0.066); however, ICD shocks (p = 0.028) and ATP/shocks combined were significantly reduced (p = 0.04). At our follow-up electrophysiology meetings PSGB was deemed ineffective in 4 of 12 patients (33%). Temporary anisocoria was seen in 2 of 12 (17%) patients, and temporary hypotension and hoarseness were reported in a single patient.

Discussion: In this limited series, PSGB showed promise as a method for temporarily stabilising refractory VA and ES in a cohort of male patients with structural heart disease. The side effects observed were mild and temporary.

Abstract Image

经皮左星状神经节阻滞治疗结构性心脏病的难治性室速:我们的单中心经验。
导言:当抗心律失常药物、深度镇静或导管消融均无法缓解电风暴(ES)时,可考虑使用自主神经调节。我们报告了经皮左星状神经节阻滞(PSGB)暂时抑制结构性心脏病患者难治性室性心律失常(VA)的经验:我院对2018年1月至2021年10月期间接受PSGB治疗难治性室性心律失常的结构性心脏病和植入式心律转复除颤器(ICD)患者进行了回顾性分析。评估了PSGB前后一周内进行抗心动过速起搏(ATP)的次数和ICD电击/体外心脏除颤的次数。对病历进行了检查,以发现潜在的并发症:12名患者共接受了15次PSGB和5次左心交感神经去支配手术。平均年龄为 73 ± 5.8 岁,所有患者均为男性。12 人中有 9 人(75%)患有缺血性心肌病,其余为非缺血性扩张型心肌病。平均左心室射血分数为 35%(± 12.2%)。12 名患者中有 8 名(66.7%)已同时接受胺碘酮和β-受体阻滞剂治疗。ATP 的降低未达到统计学意义(p = 0.066);然而,ICD 冲击(p = 0.028)和 ATP/ 冲击合计显著降低(p = 0.04)。在我们的后续电生理学会议上,12 名患者中有 4 人(33%)被认为 PSGB 无效。12 例患者中有 2 例(17%)出现暂时性失神,1 例患者出现暂时性低血压和声音嘶哑:在这一有限的系列研究中,PSGB 作为一种暂时稳定患有结构性心脏病的男性患者中难治性 VA 和 ES 的方法,显示了其前景。观察到的副作用是轻微和暂时的。
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来源期刊
Netherlands Heart Journal
Netherlands Heart Journal CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
4.70
自引率
5.00%
发文量
84
审稿时长
6-12 weeks
期刊介绍: The scope of the Netherlands Heart Journal is to contribute to the national and international literature by publishing scientific papers in the field of cardiovascular medicine. It also provides a platform for Continuing Medical Education for cardiologists and those in training for the speciality of cardiology in the Netherlands. The Netherlands Heart Journal is made available to cardiologists, cardiologists in training, cardiopulmonary surgeons, cardiopulmonary surgeons in training, internists and paediatric cardiologists. The journal is the official journal of the Netherlands Society of Cardiology.
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