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Use of 21-Valent Pneumococcal Conjugate Vaccine Among U.S. Adults: Recommendations of the Advisory Committee on Immunization Practices - United States, 2024. 美国成年人接种 21 价肺炎球菌结合疫苗的情况:免疫实践咨询委员会的建议 - 美国,2024 年。
Morbidity and Mortality Weekly Report Pub Date : 2024-09-12 DOI: 10.15585/mmwr.mm7336a3
Miwako Kobayashi,Andrew J Leidner,Ryan Gierke,Jennifer L Farrar,Rebecca L Morgan,Doug Campos-Outcalt,Robert Schechter,Katherine A Poehling,Sarah S Long,Jamie Loehr,Adam L Cohen
{"title":"Use of 21-Valent Pneumococcal Conjugate Vaccine Among U.S. Adults: Recommendations of the Advisory Committee on Immunization Practices - United States, 2024.","authors":"Miwako Kobayashi,Andrew J Leidner,Ryan Gierke,Jennifer L Farrar,Rebecca L Morgan,Doug Campos-Outcalt,Robert Schechter,Katherine A Poehling,Sarah S Long,Jamie Loehr,Adam L Cohen","doi":"10.15585/mmwr.mm7336a3","DOIUrl":"https://doi.org/10.15585/mmwr.mm7336a3","url":null,"abstract":"On June 17, 2024, the Food and Drug Administration approved 21-valent pneumococcal conjugate vaccine (PCV) (PCV21; CAPVAXIVE; Merck Sharp & Dohme, LLC) for adults aged ≥18 years. PCV21 does not contain certain serotypes that are included in other licensed pneumococcal vaccines but adds eight new serotypes. The Advisory Committee on Immunization Practices (ACIP) recommends use of a PCV for all adults aged ≥65 years, as well as adults aged 19-64 years with certain risk conditions for pneumococcal disease if they have not received a PCV or whose vaccination history is unknown. Previously, options included either 20-valent PCV (PCV20; Prevnar20; Wyeth Pharmaceuticals, Inc.) alone or a 15-valent PCV (PCV15; VAXNEUVANCE; Merck Sharp & Dohme, LLC) in series with 23-valent pneumococcal polysaccharide vaccine (PPSV23; Pneumovax23; Merck Sharp & Dohme, LLC). Additional recommendations for use of PCV20 exist for adults who started their pneumococcal vaccination series with 13-valent PCV (PCV13; Prevnar13; Wyeth Pharmaceuticals, Inc.). The ACIP Pneumococcal Vaccines Work Group employed the Evidence to Recommendations framework to guide its deliberations on PCV21 vaccination among U.S. adults. On June 27, 2024, ACIP recommended a single dose of PCV21 as an option for adults aged ≥19 years for whom PCV is currently recommended. Indications for PCV have not changed from previous recommendations. This report summarizes evidence considered for these recommendations and provides clinical guidance for use of PCV21.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"62 1","pages":"793-798"},"PeriodicalIF":0.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142231392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heat-Related Emergency Department Visits — United States, May–September 2023 美国 2023 年 5 月至 9 月与高温有关的急诊就诊人数
Morbidity and Mortality Weekly Report Pub Date : 2024-04-18 DOI: 10.15585/mmwr.mm7315a1
A. Vaidyanathan, Abigail Gates, Claudia Brown, Emily Prezzato, Aaron Bernstein
{"title":"Heat-Related Emergency Department Visits — United States, May–September 2023","authors":"A. Vaidyanathan, Abigail Gates, Claudia Brown, Emily Prezzato, Aaron Bernstein","doi":"10.15585/mmwr.mm7315a1","DOIUrl":"https://doi.org/10.15585/mmwr.mm7315a1","url":null,"abstract":"Unprecedented heat waves can affect all persons, but some are more sensitive to the effects of heat, including children and adults with underlying health conditions, pregnant women, and outdoor workers. Many regions of the United States experienced record-breaking high temperatures in 2023, with populations exposed to extremely high temperatures for prolonged periods. CDC examined emergency department (ED) visits associated with heat-related illness (HRI) from the National Syndromic Surveillance Program and compared daily HRI ED visit rates during the warm-season months (May-September) of 2023 with those during 2018-2022. In the 2023 warm-season months, daily HRI ED visit rates peaked in several regions and remained elevated for a prolonged duration. More males than females sought care in EDs for HRI, especially males aged 18-64 years. CDC issued multiple public health alerts using the Epidemic Information Exchange system to bring attention to increases in ED utilization for HRI. Deaths and illnesses associated with heat exposure are a continuing public health concern as climate change results in longer, hotter, and more frequent episodes of extreme heat. Near real-time monitoring of weather conditions and adverse health outcomes can guide public health practitioners' timing of risk communication and implementation of prevention measures associated with extreme heat.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":" 5","pages":"324 - 329"},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140687589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 Vaccination Coverage, and Rates of SARS-CoV-2 Infection and COVID-19–Associated Hospitalization Among Residents in Nursing Homes — National Healthcare Safety Network, United States, October 2023–February 2024 2023 年 10 月至 2024 年 2 月,美国国家医疗保健安全网络:COVID-19 疫苗接种覆盖率、疗养院居民 SARS-CoV-2 感染率和 COVID-19 相关住院率
Morbidity and Mortality Weekly Report Pub Date : 2024-04-18 DOI: 10.15585/mmwr.mm7315a3
David Franklin, Kira Barbre, Theresa Rowe, Hannah Reses, Jason Massey, Lu Meng, Philip Dollard, Heather Dubendris, Molly Stillions, Lindsay Robinson, Jacques W Clerville, K. J. Slifka, Andrea Benin, Jeneita Bell
{"title":"COVID-19 Vaccination Coverage, and Rates of SARS-CoV-2 Infection and COVID-19–Associated Hospitalization Among Residents in Nursing Homes — National Healthcare Safety Network, United States, October 2023–February 2024","authors":"David Franklin, Kira Barbre, Theresa Rowe, Hannah Reses, Jason Massey, Lu Meng, Philip Dollard, Heather Dubendris, Molly Stillions, Lindsay Robinson, Jacques W Clerville, K. J. Slifka, Andrea Benin, Jeneita Bell","doi":"10.15585/mmwr.mm7315a3","DOIUrl":"https://doi.org/10.15585/mmwr.mm7315a3","url":null,"abstract":"Nursing home residents are at increased risk for developing severe COVID-19. Nursing homes report weekly facility-level data on SARS-CoV-2 infections, COVID-19-associated hospitalizations, and COVID-19 vaccination coverage among residents to CDC's National Healthcare Safety Network. This analysis describes rates of incident SARS-CoV-2 infection, rates of incident COVID-19-associated hospitalization, and COVID-19 vaccination coverage during October 16, 2023-February 11, 2024. Weekly rates of SARS-CoV-2 infection ranged from 61.4 to 133.8 per 10,000 nursing home residents. The weekly percentage of facilities reporting one or more incident SARS-CoV-2 infections ranged from 14.9% to 26.1%. Weekly rates of COVID-19-associated hospitalization ranged from 3.8 to 7.1 per 10,000 residents, and the weekly percentage of facilities reporting one or more COVID-19-associated hospitalizations ranged from 2.6% to 4.7%. By February 11, 2024, 40.5% of nursing home residents had received a dose of the updated 2023-2024 COVID-19 vaccine that was first recommended in September 2023. Although the peak rate of SARS-CoV-2 infection among nursing home residents was lower during the 2023-24 respiratory virus season than during the three previous respiratory virus seasons, nursing home residents continued to be disproportionately affected by SARS-CoV-2 infection and related severe outcomes. Vaccination coverage remains suboptimal in this population. Ongoing surveillance for SARS-CoV-2 infections and COVID-19-associated hospitalizations in this population is necessary to develop and evaluate evidence-based interventions for protecting nursing home residents.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":" 2","pages":"339 - 344"},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140688550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Use of the Pfizer Pentavalent Meningococcal Vaccine Among Persons Aged ≥10 Years: Recommendations of the Advisory Committee on Immunization Practices ― United States, 2023 辉瑞五价脑膜炎球菌疫苗在年龄≥10 岁人群中的使用:免疫实践咨询委员会的建议 - 美国,2023 年
Morbidity and Mortality Weekly Report Pub Date : 2024-04-18 DOI: 10.15585/mmwr.mm7315a4
Jennifer P Collins, Samuel J Crowe, Ismael R. Ortega-Sanchez, Lynn Bahta, Doug Campos-Outcalt, Jamie Loehr, Rebecca L Morgan, K. Poehling, Lucy A McNamara
{"title":"Use of the Pfizer Pentavalent Meningococcal Vaccine Among Persons Aged ≥10 Years: Recommendations of the Advisory Committee on Immunization Practices ― United States, 2023","authors":"Jennifer P Collins, Samuel J Crowe, Ismael R. Ortega-Sanchez, Lynn Bahta, Doug Campos-Outcalt, Jamie Loehr, Rebecca L Morgan, K. Poehling, Lucy A McNamara","doi":"10.15585/mmwr.mm7315a4","DOIUrl":"https://doi.org/10.15585/mmwr.mm7315a4","url":null,"abstract":"Meningococcal disease is a life-threatening invasive infection caused by Neisseria meningitidis. Two quadrivalent (serogroups A, C, W, and Y) meningococcal conjugate vaccines (MenACWY) (MenACWY-CRM [Menveo, GSK] and MenACWY-TT [MenQuadfi, Sanofi Pasteur]) and two serogroup B meningococcal vaccines (MenB) (MenB-4C [Bexsero, GSK] and MenB-FHbp [Trumenba, Pfizer Inc.]), are licensed and available in the United States and have been recommended by CDC's Advisory Committee on Immunization Practices (ACIP). On October 20, 2023, the Food and Drug Administration approved the use of a pentavalent meningococcal vaccine (MenACWY-TT/MenB-FHbp [Penbraya, Pfizer Inc.]) for prevention of invasive disease caused by N. meningitidis serogroups A, B, C, W, and Y among persons aged 10-25 years. On October 25, 2023, ACIP recommended that MenACWY-TT/MenB-FHbp may be used when both MenACWY and MenB are indicated at the same visit for the following groups: 1) healthy persons aged 16-23 years (routine schedule) when shared clinical decision-making favors administration of MenB vaccine, and 2) persons aged ≥10 years who are at increased risk for meningococcal disease (e.g., because of persistent complement deficiencies, complement inhibitor use, or functional or anatomic asplenia). Different manufacturers' serogroup B-containing vaccines are not interchangeable; therefore, when MenACWY-TT/MenB-FHbp is used, subsequent doses of MenB should be from the same manufacturer (Pfizer Inc.). This report summarizes evidence considered for these recommendations and provides clinical guidance for the use of MenACWY-TT/MenB-FHbp.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":" 45","pages":"345 - 350"},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140687546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Durability of Original Monovalent mRNA Vaccine Effectiveness Against COVID-19 Omicron–Associated Hospitalization in Children and Adolescents — United States, 2021–2023 2021-2023 年美国原始单价 mRNA 疫苗在预防 COVID-19 Omicron 相关儿童和青少年住院治疗方面的效力持续时间
Morbidity and Mortality Weekly Report Pub Date : 2024-04-18 DOI: 10.15585/mmwr.mm7315a2
Laura D. Zambrano, Margaret M. Newhams, Regina M Simeone, Amanda B. Payne, Michael Wu, Amber O Orzel-Lockwood, N. Halasa, Jemima M Calixte, Pia S Pannaraj, K. Mongkolrattanothai, J. Boom, Leila C. Sahni, S. Kamidani, K. Chiotos, M. Cameron, A. Maddux, K. Irby, J. Schuster, E. Mack, Austin Biggs, B. Coates, Kelly N. Michelson, Katherine E Bline, Ryan A Nofziger, Hillary R Crandall, Charlotte V Hobbs, S. Gertz, Sabrina M. Heidemann, T. Bradford, Tracie C Walker, S. Schwartz, M. Staat, Samina S Bhumbra, J. Hume, Michele Kong, M. Stockwell, Thomas J Connors, M. Cullimore, H. Flori, Emily R Levy, N. Cvijanovich, M. Zinter, Mia Maamari, Cindy Bowens, Danielle M. Zerr, J. Guzman-Cottrill, Ivan Gonzalez, Angela P Campbell, Adrienne G Randolph, M. Murdock, Heather Kelley, Candice Colston, Ronald C. Sanders, Laura Miron, M. Yates, Ashlyn Madding, Alexa Dixon, Michael Henne, Kathleen Sun, Jazmin Baez Maidana, Natalie Triester, Jaycee Jumarang, Daniel Hakimi, Kennis-Grace Mrotek, Liria Muriscot Niell, Natasha Baig, E
{"title":"Durability of Original Monovalent mRNA Vaccine Effectiveness Against COVID-19 Omicron–Associated Hospitalization in Children and Adolescents — United States, 2021–2023","authors":"Laura D. Zambrano, Margaret M. Newhams, Regina M Simeone, Amanda B. Payne, Michael Wu, Amber O Orzel-Lockwood, N. Halasa, Jemima M Calixte, Pia S Pannaraj, K. Mongkolrattanothai, J. Boom, Leila C. Sahni, S. Kamidani, K. Chiotos, M. Cameron, A. Maddux, K. Irby, J. Schuster, E. Mack, Austin Biggs, B. Coates, Kelly N. Michelson, Katherine E Bline, Ryan A Nofziger, Hillary R Crandall, Charlotte V Hobbs, S. Gertz, Sabrina M. Heidemann, T. Bradford, Tracie C Walker, S. Schwartz, M. Staat, Samina S Bhumbra, J. Hume, Michele Kong, M. Stockwell, Thomas J Connors, M. Cullimore, H. Flori, Emily R Levy, N. Cvijanovich, M. Zinter, Mia Maamari, Cindy Bowens, Danielle M. Zerr, J. Guzman-Cottrill, Ivan Gonzalez, Angela P Campbell, Adrienne G Randolph, M. Murdock, Heather Kelley, Candice Colston, Ronald C. Sanders, Laura Miron, M. Yates, Ashlyn Madding, Alexa Dixon, Michael Henne, Kathleen Sun, Jazmin Baez Maidana, Natalie Triester, Jaycee Jumarang, Daniel Hakimi, Kennis-Grace Mrotek, Liria Muriscot Niell, Natasha Baig, E","doi":"10.15585/mmwr.mm7315a2","DOIUrl":"https://doi.org/10.15585/mmwr.mm7315a2","url":null,"abstract":"Pediatric COVID-19 vaccination is effective in preventing COVID-19-related hospitalization, but duration of protection of the original monovalent vaccine during SARS-CoV-2 Omicron predominance merits evaluation, particularly given low coverage with updated COVID-19 vaccines. During December 19, 2021-October 29, 2023, the Overcoming COVID-19 Network evaluated vaccine effectiveness (VE) of ≥2 original monovalent COVID-19 mRNA vaccine doses against COVID-19-related hospitalization and critical illness among U.S. children and adolescents aged 5-18 years, using a case-control design. Too few children and adolescents received bivalent or updated monovalent vaccines to separately evaluate their effectiveness. Most case-patients (persons with a positive SARS-CoV-2 test result) were unvaccinated, despite the high frequency of reported underlying conditions associated with severe COVID-19. VE of the original monovalent vaccine against COVID-19-related hospitalizations was 52% (95% CI = 33%-66%) when the most recent dose was administered <120 days before hospitalization and 19% (95% CI = 2%-32%) if the interval was 120-364 days. VE of the original monovalent vaccine against COVID-19-related hospitalization was 31% (95% CI = 18%-43%) if the last dose was received any time within the previous year. VE against critical COVID-19-related illness, defined as receipt of noninvasive or invasive mechanical ventilation, vasoactive infusions, extracorporeal membrane oxygenation, and illness resulting in death, was 57% (95% CI = 21%-76%) when the most recent dose was received <120 days before hospitalization, 25% (95% CI = -9% to 49%) if it was received 120-364 days before hospitalization, and 38% (95% CI = 15%-55%) if the last dose was received any time within the previous year. VE was similar after excluding children and adolescents with documented immunocompromising conditions. Because of the low frequency of children who received updated COVID-19 vaccines and waning effectiveness of original monovalent doses, these data support CDC recommendations that all children and adolescents receive updated COVID-19 vaccines to protect against severe COVID-19.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":" 39","pages":"330 - 338"},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140689006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measles — United States, January 1, 2020–March 28, 2024 麻疹 - 美国,2020 年 1 月 1 日至 2024 年 3 月 28 日
Morbidity and Mortality Weekly Report Pub Date : 2024-04-11 DOI: 10.15585/mmwr.mm7314a1
Adria D Mathis, Kelley Raines, Nina B. Masters, Thomas D. Filardo, Gimin Kim, Stephen N Crooke, Bettina Bankamp, Paul A. Rota, David E Sugerman
{"title":"Measles — United States, January 1, 2020–March 28, 2024","authors":"Adria D Mathis, Kelley Raines, Nina B. Masters, Thomas D. Filardo, Gimin Kim, Stephen N Crooke, Bettina Bankamp, Paul A. Rota, David E Sugerman","doi":"10.15585/mmwr.mm7314a1","DOIUrl":"https://doi.org/10.15585/mmwr.mm7314a1","url":null,"abstract":"Measles is a highly infectious febrile rash illness and was declared eliminated in the United States in 2000. However, measles importations continue to occur, and U.S. measles elimination status was threatened in 2019 as the result of two prolonged outbreaks among undervaccinated communities in New York and New York City. To assess U.S. measles elimination status after the 2019 outbreaks and to provide context to understand more recent increases in measles cases, CDC analyzed epidemiologic and laboratory surveillance data and the performance of the U.S. measles surveillance system after these outbreaks. During January 1, 2020-March 28, 2024, CDC was notified of 338 confirmed measles cases; 97 (29%) of these cases occurred during the first quarter of 2024, representing a more than seventeenfold increase over the mean number of cases reported during the first quarter of 2020-2023. Among the 338 reported cases, the median patient age was 3 years (range = 0-64 years); 309 (91%) patients were unvaccinated or had unknown vaccination status, and 336 case investigations included information on ≥80% of critical surveillance indicators. During 2020-2023, the longest transmission chain lasted 63 days. As of the end of 2023, because of the absence of sustained measles virus transmission for 12 consecutive months in the presence of a well-performing surveillance system, U.S. measles elimination status was maintained. Risk for widespread U.S. measles transmission remains low because of high population immunity. However, because of the increase in cases during the first quarter of 2024, additional activities are needed to increase U.S. routine measles, mumps, and rubella vaccination coverage, especially among close-knit and undervaccinated communities. These activities include encouraging vaccination before international travel and rapidly investigating suspected measles cases.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"28 3","pages":"295 - 300"},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140714564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Risk for Sudden Cardiac Death Among Adolescents and Young Adults After Receipt of COVID-19 Vaccine — Oregon, June 2021–December 2022 青少年接种 COVID-19 疫苗后心脏性猝死风险评估 - 俄勒冈州,2021 年 6 月至 2022 年 12 月
Morbidity and Mortality Weekly Report Pub Date : 2024-04-11 DOI: 10.15585/mmwr.mm7314a5
Juventila Liko, Paul R. Cieslak
{"title":"Assessment of Risk for Sudden Cardiac Death Among Adolescents and Young Adults After Receipt of COVID-19 Vaccine — Oregon, June 2021–December 2022","authors":"Juventila Liko, Paul R. Cieslak","doi":"10.15585/mmwr.mm7314a5","DOIUrl":"https://doi.org/10.15585/mmwr.mm7314a5","url":null,"abstract":"COVID-19 vaccination has been associated with myocarditis in adolescents and young adults, and concerns have been raised about possible vaccine-related cardiac fatalities in this age group. In April 2021, cases of myocarditis after COVID-19 vaccination, particularly among young male vaccine recipients, were reported to the Vaccine Adverse Event Reporting System. To assess this possibility, investigators searched death certificates for Oregon residents aged 16-30 years who died during June 2021-December 2022 for cardiac or undetermined causes of death. For identified decedents, records in Oregon's immunization information system were reviewed for documentation of mRNA COVID-19 vaccination received ≤100 days before death. Among 1,292 identified deaths, COVID-19 was cited as the cause for 30. For 101 others, a cardiac cause of death could not be excluded; among these decedents, immunization information system records were available for 88, three of whom had received an mRNA COVID-19 vaccination within 100 days of death. Of 40 deaths that occurred among persons who had received an mRNA COVID-19 vaccine dose, three occurred ≤100 days after vaccination. Two of these deaths were attributed to chronic underlying conditions; the cause was undetermined for one. No death certificate attributed death to vaccination. These data do not support an association between receipt of mRNA COVID-19 vaccine and sudden cardiac death among previously healthy young persons. COVID-19 vaccination is recommended for all persons aged ≥6 months to prevent COVID-19 and complications, including death.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"4 3","pages":"317 - 320"},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140714859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
COVID-19 Vaccination Coverage — World Health Organization African Region, 2021–2023 COVID-19 疫苗接种覆盖率 - 世界卫生组织非洲地区,2021-2023 年
Morbidity and Mortality Weekly Report Pub Date : 2024-04-11 DOI: 10.15585/mmwr.mm7314a3
Reena H Doshi, Sheillah Nsasiirwe, Melissa Dahlke, A. Atagbaza, Oniovo Efe Aluta, Alain Blaise Tatsinkou, Ezekiel Dauda, Alba Vilajeliu, Santosh Gurung, Jayne Tusiime, Fiona Braka, A. Bwaka, Sarah Wanyoike, Donald Brooks, Diana Chang Blanc, James P. Alexander, Benjamin A. Dahl, Ann Lindstrand, C. S. Wiysonge
{"title":"COVID-19 Vaccination Coverage — World Health Organization African Region, 2021–2023","authors":"Reena H Doshi, Sheillah Nsasiirwe, Melissa Dahlke, A. Atagbaza, Oniovo Efe Aluta, Alain Blaise Tatsinkou, Ezekiel Dauda, Alba Vilajeliu, Santosh Gurung, Jayne Tusiime, Fiona Braka, A. Bwaka, Sarah Wanyoike, Donald Brooks, Diana Chang Blanc, James P. Alexander, Benjamin A. Dahl, Ann Lindstrand, C. S. Wiysonge","doi":"10.15585/mmwr.mm7314a3","DOIUrl":"https://doi.org/10.15585/mmwr.mm7314a3","url":null,"abstract":"With the availability of authorized COVID-19 vaccines in early 2021, vaccination became an effective tool to reduce COVID-19-associated morbidity and mortality. Initially, the World Health Organization (WHO) set an ambitious target to vaccinate 70% of the global population by mid-2022. However, in July 2022, WHO recommended that all countries, including those in the African Region, prioritize COVID-19 vaccination of high-risk groups, including older adults and health care workers, to have the greatest impact on morbidity and mortality. As of December 31, 2023, approximately 860 million doses of COVID-19 vaccine had been delivered to countries in the African Region, and 646 million doses had been administered. Cumulatively, 38% of the African Region's population had received ≥1 dose, 32% had completed a primary series, and 21% had received ≥1 booster dose. Cumulative total population coverage with ≥1 dose ranged by country from 0.3% to 89%. Coverage with the primary series among older age groups was 52% (range among countries = 15%-96%); primary series coverage among health care workers was 48% (range = 13%-99%). Although the COVID-19 public health emergency of international concern was declared over in May 2023, current WHO recommendations reinforce the need to vaccinate priority populations at highest risk for severe COVID-19 disease and death and build more sustainable programs by integrating COVID-19 vaccination into primary health care, strengthening immunization across the life course, and improving pandemic preparedness.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"11 13","pages":"307 - 311"},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140715693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infections Associated with Medtronic Duet External Ventricular Drains — Rhode Island Hospital, Providence, Rhode Island, January 2023–January 2024 与美敦力 Duet 室外引流管有关的感染 - 罗德岛普罗维登斯罗德岛医院,2023 年 1 月至 2024 年 1 月
Morbidity and Mortality Weekly Report Pub Date : 2024-04-11 DOI: 10.15585/mmwr.mm7314a4
Kevin M Gibas, Dianne B. Auld, Stephanie Parente, Jean Horoho, Leonard A. Mermel
{"title":"Infections Associated with Medtronic Duet External Ventricular Drains — Rhode Island Hospital, Providence, Rhode Island, January 2023–January 2024","authors":"Kevin M Gibas, Dianne B. Auld, Stephanie Parente, Jean Horoho, Leonard A. Mermel","doi":"10.15585/mmwr.mm7314a4","DOIUrl":"https://doi.org/10.15585/mmwr.mm7314a4","url":null,"abstract":"External ventricular drains (EVDs) are medical devices that are inserted into the ventricles of the brain to drain excess fluid, manage intracranial hypertension, monitor intracranial pressure, and administer medications. Unintentional disconnections and breaks or fractures (breaks) of EVDs or associated drainage system components can result in cerebrospinal fluid (CSF) leakage and increased risk for EVD-associated infections. After replacement of Integra Life Sciences EVD systems with Medtronic Duet EVD systems at Rhode Island Hospital in mid-September 2023, a threefold increase was observed in the prevalence of positive CSF cultures, from 2.8 per 1,000 days with an EVD in place (EVD days) during January-September 2023 to 11.4 per 1,000 EVD days during October 2023-January 2024 (rate ratio [RR] = 5.7; 95% CI = 1.5-22.0; p = 0.01) and an eightfold increase in the prevalence of infections, from 0.7 to 6.5 per 1,000 EVD days (RR = 9.8; 95% CI = 1.1-87.3; p = 0.04). An investigation by Rhode Island Hospital Infection Control during December 2023-January 2024 identified frequent reports of disconnections and breaks of the Medtronic Duet EVD system. A search of the Food and Drug Administration Manufacturer and User Facility Device Experience database identified 326 reports nationwide of disconnection and breaks of components of the Duet EVD system, including 175 during 2023. A Medical Product Safety Network report was filed. The Duet EVD product was ultimately recalled in January 2024, citing disconnections of the EVD system and reports of CSF leakage and infection. Given the widespread use of EVD systems by neurosurgery centers and the risk for EVD-associated infections, a strategy for future consideration by hospital infection prevention and control programs might be inclusion of EVD-associated infections in hospital surveillance programs to rapidly identify increases in these events and determine factors related to such infections to prevent additional infections.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"20 4","pages":"312 - 316"},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140714426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
State Medicaid Coverage for Tobacco Cessation Treatments and Barriers to Accessing Treatments — United States, 2018–2022 2018-2022年美国各州医疗补助对戒烟治疗的覆盖范围和获得治疗的障碍
Morbidity and Mortality Weekly Report Pub Date : 2024-04-11 DOI: 10.15585/mmwr.mm7314a2
Anne DiGiulio, Michael A. Tynan, A. Schecter, Kisha-Ann S. Williams, Brenna VanFrank
{"title":"State Medicaid Coverage for Tobacco Cessation Treatments and Barriers to Accessing Treatments — United States, 2018–2022","authors":"Anne DiGiulio, Michael A. Tynan, A. Schecter, Kisha-Ann S. Williams, Brenna VanFrank","doi":"10.15585/mmwr.mm7314a2","DOIUrl":"https://doi.org/10.15585/mmwr.mm7314a2","url":null,"abstract":"The prevalence of cigarette smoking among U.S. adults enrolled in Medicaid is higher than among adults with private insurance; more than one in five adults enrolled in Medicaid smokes cigarettes. Smoking cessation reduces the risk for smoking-related disease and death. Effective treatments for smoking cessation are available, and comprehensive, barrier-free insurance coverage of these treatments can increase cessation. However, Medicaid treatment coverage and treatment access barriers vary by state. The American Lung Association collected and analyzed state-level information regarding coverage for nine tobacco cessation treatments and seven access barriers for standard Medicaid enrollees. As of December 31, 2022, a total of 20 state Medicaid programs provided comprehensive coverage (all nine treatments), an increase from 15 as of December 31, 2018. Only three states had zero access barriers, an increase from two; all three also had comprehensive coverage. Although states continue to improve smoking cessation treatment coverage and decrease access barriers for standard Medicaid enrollees, coverage gaps and access barriers remain in many states. State Medicaid programs can improve the health of enrollees who smoke and potentially reduce health care expenditures by providing barrier-free coverage of all evidence-based cessation treatments and by promoting this coverage to enrollees and providers.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"8 19","pages":"301 - 306"},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140713046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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