Adriana S Lopez,Randall English,Shannon L Rogers,Brian Emery,Leah A Goldstein,Claire M Midgley,Heidi L Moline,Terry Fei Fan Ng,
{"title":"Acute Flaccid Myelitis Surveillance - United States, January 2020-December 2025.","authors":"Adriana S Lopez,Randall English,Shannon L Rogers,Brian Emery,Leah A Goldstein,Claire M Midgley,Heidi L Moline,Terry Fei Fan Ng, ","doi":"10.15585/mmwr.mm7526a1","DOIUrl":"https://doi.org/10.15585/mmwr.mm7526a1","url":null,"abstract":"Acute flaccid myelitis (AFM) is a rare but serious neurologic condition that causes paralysis and primarily affects children. Clinically and radiologically, AFM is indistinguishable from the acute flaccid paralysis of poliomyelitis caused by poliovirus. Nationwide surveillance for AFM has been conducted in the United States since 2014, when an increase in AFM was first recognized. Laboratory testing and epidemiologic and clinical data collected through surveillance suggest that enteroviruses, particularly enterovirus D68 (EV-D68), are a common cause of AFM. EV-D68 circulation was associated with biennial peaks in AFM cases in the United States in 2014, 2016, and 2018. This report provides an update to nationwide surveillance of confirmed AFM cases during January 2020-December 2025. During this period, the number of confirmed AFM cases reported to CDC remained low (17-48 cases per year) compared with 2014, 2016, and 2018 (120-238 cases per year). Despite ongoing seasonal enterovirus circulation, including increases in EV-D68-associated respiratory illnesses identified from sentinel surveillance sites in 2022, 2024, and 2025, concurrent increases in AFM cases in nationwide surveillance data were not observed; EV-D68 was detected in one AFM patient specimen received by CDC during this period. A majority (approximately 75%) of confirmed cases of AFM occurred in persons who were reported to be up to date with polio vaccination; approximately one half had stool specimens collected and tested. In 2022, a polio case in an unvaccinated person was identified by testing stool specimens collected through AFM surveillance. Clinicians should ensure that stool samples are collected from patients with acute onset of flaccid weakness or paralysis and report all cases to their local health department.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"28 1","pages":"329-336"},"PeriodicalIF":0.0,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148415925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Gallalee,Hannah M Cranford,Aubrey Drummond,Lisa LaPlace Ekpo,Brett R Ellis,Esther M Ellis
{"title":"Legionellosis Outbreaks Associated with Two Hotels - U.S. Virgin Islands, October 2024-April 2025.","authors":"Sarah Gallalee,Hannah M Cranford,Aubrey Drummond,Lisa LaPlace Ekpo,Brett R Ellis,Esther M Ellis","doi":"10.15585/mmwr.mm7525a2","DOIUrl":"https://doi.org/10.15585/mmwr.mm7525a2","url":null,"abstract":"Legionellosis is a bacterial disease caused by inhalation or aspiration of Legionella bacteria; Legionnaires disease is a type of legionellosis characterized by illness with pneumonia. During November 2024, the U.S. Virgin Islands (USVI) Department of Health (VIDOH) was notified of two confirmed Legionnaires disease cases among travelers to two different hotels on St. Croix Island. VIDOH investigated to determine exposure sources and prevent additional cases. Two additional legionellosis cases were identified. The four patients with cases were aged 53-73 years; two patients were hospitalized and none died. At hotel A, L. pneumophila was detected in three of 21 (14%) environmental samples. VIDOH required hotel A to close one guest room, remediate, and retest. At hotel B, L. pneumophila was detected in 22 of 40 (55%) samples. VIDOH required hotel B to cease hotel operations until remediation and retesting were completed. L. pneumophila was isolated from shower samples at both hotels, in the cistern and cold water system at hotel A, and in cold and hot water systems at hotel B. The two USVI outbreaks underscore the importance of reporting legionellosis among returned travelers to facilitate local public health investigations and prevent additional cases. In addition, in tropical climates, cold water systems operate at temperatures favorable for Legionella growth (77°F-113°F [25°C-45°C]), highlighting the importance of effective water management programs and water system disinfection to prevent disease spread.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"169 1","pages":"322-326"},"PeriodicalIF":0.0,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148372410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eleanor F Saunders,Marissa L Taylor,Emma S Jones,Brad J Biggerstaff,Julia M Vorobiov,David W McCormick,Marion C Lanteri,Valerie Green,Brian Custer,Laura Tonnetti,Gilbert J Kersh,Scott P Commins,Johanna S Salzer
{"title":"Alpha-gal Immunoglobulin E Seroprevalence Among Blood Donors - 10 States, 2024-2025.","authors":"Eleanor F Saunders,Marissa L Taylor,Emma S Jones,Brad J Biggerstaff,Julia M Vorobiov,David W McCormick,Marion C Lanteri,Valerie Green,Brian Custer,Laura Tonnetti,Gilbert J Kersh,Scott P Commins,Johanna S Salzer","doi":"10.15585/mmwr.mm7525a1","DOIUrl":"https://doi.org/10.15585/mmwr.mm7525a1","url":null,"abstract":"Alpha-gal syndrome (AGS) is an emerging, noninfectious tickborne disease characterized by an allergic reaction to galactose-α-1,3-galactose (alpha-gal), an oligosaccharide found in red (mammalian) meat and other mammalian products such as dairy and gelatin. As of 2022, AGS was estimated to affect up to 450,000 persons in the United States (1). Anaphylactic AGS reactions can be fatal, and AGS allergic reactions encompass a range of symptoms including urticaria, angioedema, wheezing, and gastrointestinal distress. AGS is primarily managed through an avoidance diet. The U.S. geographic distribution of AGS is closely associated with the range of the lone star tick (Amblyomma americanum); bites from this tick introduce alpha-gal through its saliva, which can trigger the allergy. Diagnosis of AGS requires both the presence of clinically compatible symptoms and the detection of serologic immunoglobulin E (IgE) antibodies against alpha-gal. Persons can have alpha-gal-specific IgE antibodies without clinical symptoms. The proportion of persons in the United States who are seropositive for alpha-gal IgE is unknown. To better understand the distribution and seroprevalence of alpha-gal IgE among U.S. adults, 3,000 serum samples collected during November 2024-April 2025 from blood donors living in 10 states were tested for the presence of alpha-gal IgE antibodies. States previously reported to have high numbers of suspected AGS cases were found to have correspondingly high seroprevalences. Among the 10 states, the highest estimated seroprevalences among persons aged ≥16 years were detected in Arkansas (31.2%) and Missouri (26.0%). These findings can guide the development of surveillance systems for AGS and help identify regions at increased risk.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"34 1","pages":"315-321"},"PeriodicalIF":0.0,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148372411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"QuickStats: Percentage of Births in Which Women Received Prenatal Care in the First Trimester of Pregnancy, by State - United States, 2024.","authors":"","doi":"10.15585/mmwr.mm7525a3","DOIUrl":"https://doi.org/10.15585/mmwr.mm7525a3","url":null,"abstract":"","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"2 1","pages":"327"},"PeriodicalIF":0.0,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148372412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bhavna Singichetti,Alison L Cammack,Patrick Rekieta,Amy Schumacher,Katharina L van Santen,Wojciech Kaczkowski,Lakshmi Radhakrishnan,Kayla N Anderson,Michael F Ballesteros,Robin Lee
{"title":"Emergency Department Visits for Suspected Suicide Attempts - United States, 2021-2025.","authors":"Bhavna Singichetti,Alison L Cammack,Patrick Rekieta,Amy Schumacher,Katharina L van Santen,Wojciech Kaczkowski,Lakshmi Radhakrishnan,Kayla N Anderson,Michael F Ballesteros,Robin Lee","doi":"10.15585/mmwr.mm7524a1","DOIUrl":"https://doi.org/10.15585/mmwr.mm7524a1","url":null,"abstract":"Suicide is a substantial public health problem. In 2024, approximately 49,000 persons died by suicide in the United States, and an estimated 2.9 million persons aged ≥12 years reported having attempted suicide. Emergency department (ED) visits for suspected suicide attempts among adolescents increased during 2020-2021, then decreased in 2022; reports based on more recent data, including ED visits for suicide attempts among older age groups, are lacking. National Syndromic Surveillance Program data were examined overall and by sex and age group to identify changes in ED visits for suspected suicide attempts. During 2021-2025, numbers of ED visits for suspected suicide attempts and proportions of those visits among all ED visits for any reason (visit proportions) were highest among adolescents aged 12-17 years compared with other age groups and were higher among females than among males. Compared with 2021, overall visit proportions in 2025 declined 7.0%, with the largest decreases occurring among adolescents aged 12-17 years (20.8% decline) and females (10.7% decline). Visit proportions increased among adults in age groups ≥26 years (range = 1.4%-15.2%). These findings highlight the need for suicide prevention in all groups, particularly in those with high or increasing proportions of suicide attempts. Timely monitoring of suicide-related data and a comprehensive approach that both prevents suicidal behavior by addressing multiple risk and protective factors and also supports those who have attempted suicide are critical for saving lives.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"67 1","pages":"304-310"},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148322661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Stewart,Amanda Dinwiddie,April Wisdom,Thomas Gilson
{"title":"Notes from the Field: Drug Overdose Deaths in Hotels and Motels - United States, 2022-2024.","authors":"Andrea Stewart,Amanda Dinwiddie,April Wisdom,Thomas Gilson","doi":"10.15585/mmwr.mm7524a2","DOIUrl":"https://doi.org/10.15585/mmwr.mm7524a2","url":null,"abstract":"","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"31 1","pages":"311-313"},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148322660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeneita M Bell,Kira Barbre,Lu Meng,Brynn Lape-Newman,Emily Wong,Austin Woods,Elizabeth J Kalayil,Heather Dubendris,Molly Stillions Prosper,Jonathan Edwards,Minn M Soe,David T Kuhar,Matthew J Stuckey,Megan C Lindley,Andrea Benin
{"title":"Influenza Vaccination Coverage Among Nursing Home Residents and Health Care Personnel - United States, 2024-25 Influenza Season.","authors":"Jeneita M Bell,Kira Barbre,Lu Meng,Brynn Lape-Newman,Emily Wong,Austin Woods,Elizabeth J Kalayil,Heather Dubendris,Molly Stillions Prosper,Jonathan Edwards,Minn M Soe,David T Kuhar,Matthew J Stuckey,Megan C Lindley,Andrea Benin","doi":"10.15585/mmwr.mm7515a1","DOIUrl":"https://doi.org/10.15585/mmwr.mm7515a1","url":null,"abstract":"Nursing home residents and health care personnel (HCP) are at increased risk for exposure to influenza; in addition, residents of nursing homes who acquire influenza are at increased risk for severe disease. The Advisory Committee on Immunization Practices recommends routine annual seasonal influenza vaccination for persons without contraindications, including HCP and those at increased risk for severe influenza. Nursing homes report influenza vaccination among residents and HCP to CDC's National Healthcare Safety Network. This report describes influenza vaccination coverage among nursing home residents and HCP working in nursing homes during the 2024-25 influenza season (October 1, 2024-March 31, 2025). At the end of the 2024-25 influenza season, influenza vaccination coverage was 61.3% among nursing home residents and 42.1% among HCP who work in nursing homes; coverage among HCP varied by employment type. This study is the first comprehensive, national assessment of influenza vaccination coverage among nursing home residents and HCP who work in nursing homes in the United States. Monitoring of influenza vaccination coverage in this population at high risk for influenza exposure and severe influenza disease, along with implementation of a combination of influenza vaccination, administration of influenza antiviral medications, and other recommended practices to control the spread and severity of influenza in nursing home settings, can help protect nursing home residents and HCP against severe influenza-associated outcomes.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"32 1","pages":"195-201"},"PeriodicalIF":0.0,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147735379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roberta Lugo Robles,Alida M Gertz,Francisco Alvarado-Ramy,Adelaide Asare,Kristen Pringle,Kara Adams,Yonette Hercules,Mayra Garcia Brown,Justice King,Linda C Pimentel,Faisal S Minhaj,Clive Brown,Sundari Mase,Shannon Gearhart
{"title":"Notes from the Field: Contact Tracing for Monkeypox virus Clade I Cases Associated with Air Travel - United States, November 2024-January 2025.","authors":"Roberta Lugo Robles,Alida M Gertz,Francisco Alvarado-Ramy,Adelaide Asare,Kristen Pringle,Kara Adams,Yonette Hercules,Mayra Garcia Brown,Justice King,Linda C Pimentel,Faisal S Minhaj,Clive Brown,Sundari Mase,Shannon Gearhart","doi":"10.15585/mmwr.mm7515a2","DOIUrl":"https://doi.org/10.15585/mmwr.mm7515a2","url":null,"abstract":"Monkeypox is a vesicular rash illness caused by Monkeypox virus (MPXV), which can be divided into clades (e.g., clade I and II), each of which includes subclades. MPXV is usually transmitted from person to person through close, sustained physical contact. Global spread of clade II MPXV began in 2022; to date, approximately 37,500 cases have been reported in the United States (provisional data), and domestic transmission is ongoing. CDC began conducting aircraft contact investigations for clade II MPXV in 2021. In February 2023, based on data showing no evidence of in-flight transmission of clade II MPXV, CDC discontinued routine aircraft contact investigations. Although outcome data were missing for approximately one third of identified aircraft contacts, a 2024 report describing data from 2021 to 2022 on clade II MPXV transmission risk during commercial air travel found no secondary cases reported among 1,538 persons who had contact with 113 infected travelers on 221 flights (1).","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"68 1","pages":"202-203"},"PeriodicalIF":0.0,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147735249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer P Collins,Heather M Scobie,Shalabh Sharma,Eric J Chow,Amy B Rubis,Tasha Martin,Nicholas R Graff,Matthew Redlinger,Saba Zewdie,Louisa Castrodale,Julia C Bennett,George A Conway,Chas DeBolt,Laurie Orell,Sarah Talia Himmelfarb,Kristen Moore,Ferric C Fang,Carolynn DeByle,Camerin A Rencken,Joe McLaughlin,Michael L Tran,Chi N Hua,Basanta Wagle,Jennifer Dolan Thomas,LeAnne M Fox,Jessica R MacNeil
{"title":"Clusters of Invasive Haemophilus influenzae Type b Disease Among Adults Using Substances or Experiencing Homelessness or Housing Instability - Alaska, Oregon, and Washington, 2023─2025.","authors":"Jennifer P Collins,Heather M Scobie,Shalabh Sharma,Eric J Chow,Amy B Rubis,Tasha Martin,Nicholas R Graff,Matthew Redlinger,Saba Zewdie,Louisa Castrodale,Julia C Bennett,George A Conway,Chas DeBolt,Laurie Orell,Sarah Talia Himmelfarb,Kristen Moore,Ferric C Fang,Carolynn DeByle,Camerin A Rencken,Joe McLaughlin,Michael L Tran,Chi N Hua,Basanta Wagle,Jennifer Dolan Thomas,LeAnne M Fox,Jessica R MacNeil","doi":"10.15585/mmwr.mm7514a1","DOIUrl":"https://doi.org/10.15585/mmwr.mm7514a1","url":null,"abstract":"","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"18 1","pages":"186-191"},"PeriodicalIF":0.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147695214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katherine L Campbell,Avnika B Amin,Jessica Goswitz,Rebecca Betz,Stacey Moyer,Jayne Griffith,Kris K Carter,Christine Hahn,Michelle M Hughes
{"title":"Notes from the Field: Tetanus in Four Children - Idaho, Minnesota, Missouri, and Wisconsin, 2024.","authors":"Katherine L Campbell,Avnika B Amin,Jessica Goswitz,Rebecca Betz,Stacey Moyer,Jayne Griffith,Kris K Carter,Christine Hahn,Michelle M Hughes","doi":"10.15585/mmwr.mm7514a2","DOIUrl":"https://doi.org/10.15585/mmwr.mm7514a2","url":null,"abstract":"","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"8 1","pages":"192-193"},"PeriodicalIF":0.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147695215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}