{"title":"QuickStats: Percentage of Suicides* and Homicides† Involving a Firearm Among Persons Aged ≥10 Years, by Age Group - United States, 2022.","authors":"","doi":"10.15585/mmwr.mm7337a3","DOIUrl":"https://doi.org/10.15585/mmwr.mm7337a3","url":null,"abstract":"","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"127 1","pages":"828"},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142273399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lakshmi Panagiotakopoulos,Danielle L Moulia,Monica Godfrey,Ruth Link-Gelles,Lauren Roper,Fiona P Havers,Christopher A Taylor,Shannon Stokley,H Keipp Talbot,Robert Schechter,Oliver Brooks,Matthew F Daley,Katherine E Fleming-Dutra,Megan Wallace
{"title":"Use of COVID-19 Vaccines for Persons Aged ≥6 Months: Recommendations of the Advisory Committee on Immunization Practices - United States, 2024-2025.","authors":"Lakshmi Panagiotakopoulos,Danielle L Moulia,Monica Godfrey,Ruth Link-Gelles,Lauren Roper,Fiona P Havers,Christopher A Taylor,Shannon Stokley,H Keipp Talbot,Robert Schechter,Oliver Brooks,Matthew F Daley,Katherine E Fleming-Dutra,Megan Wallace","doi":"10.15585/mmwr.mm7337e2","DOIUrl":"https://doi.org/10.15585/mmwr.mm7337e2","url":null,"abstract":"COVID-19 vaccination provides additional protection against severe COVID-19-associated illness and death. Since September 2023, 2023-2024 Formula monovalent XBB.1-strain COVID-19 vaccines have been recommended for use in the United States for all persons aged ≥6 months. However, SARS-CoV-2 continues to evolve, and since winter 2023-2024, Omicron JN.1 lineage strains of SARS-CoV-2, including the JN.1 strain and the KP.2 strain, have been widely circulating in the United States. Further, COVID-19 vaccine effectiveness is known to wane. On June 27, 2024, the Advisory Committee on Immunization Practices (ACIP) recommended 2024-2025 COVID-19 vaccination with a Food and Drug Administration (FDA)-approved or authorized vaccine for all persons aged ≥6 months. On August 22, 2024, FDA approved the 2024-2025 COVID-19 vaccines by Moderna and Pfizer-BioNTech (based on the KP.2 strain) for use in persons aged ≥12 years and authorized these vaccines for use in children aged 6 months-11 years under Emergency Use Authorization (EUA). On August 30, 2024, FDA authorized 2024-2025 COVID-19 vaccine by Novavax (based on the JN.1 strain) for use in persons aged ≥12 years under EUA. ACIP will continue to evaluate new evidence as it becomes available and will update recommendations as needed.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"19 1","pages":"819-824"},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142273372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rieza H Soelaeman,Danielle Kleven,Jena Losch,Michael Vega,S Nicole Fehrenbach,Jessica N Ricaldi,Diana Valencia,Scott Santibañez
{"title":"Notes from the Field: Support for Wastewater Monitoring and Influence on Protective Behavioral Intentions Among Adults - United States, July 2024.","authors":"Rieza H Soelaeman,Danielle Kleven,Jena Losch,Michael Vega,S Nicole Fehrenbach,Jessica N Ricaldi,Diana Valencia,Scott Santibañez","doi":"10.15585/mmwr.mm7337a2","DOIUrl":"https://doi.org/10.15585/mmwr.mm7337a2","url":null,"abstract":"In 2020, during the COVID-19 pandemic, CDC established the National Wastewater Surveillance System and later expanded it to include mpox and influenza A data dashboards.† Wastewater utility partners have cited community health benefits as a motivating factor for participating in wastewater surveillance; a lack of public support for wastewater surveillance activities might lead utility partners to cease participation (1,2). However, little is known about public support for wastewater monitoring and its influence on protective health behaviors. As innovative surveillance strategies such as wastewater surveillance evolve, ethical considerations, including understanding public perceptions regarding support for these activities and potential risks to communities, are essential (3).","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"213 1","pages":"825-827"},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142273394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Souci Louis,Miguella Mark-Carew,Matthew Biggerstaff,Jonathan Yoder,Alexandria B Boehm,Marlene K Wolfe,Matthew Flood,Susan Peters,Mary Grace Stobierski,Joseph Coyle,Matthew T Leslie,Mallory Sinner,Dawn Nims,Victoria Salinas,Layla Lustri,Heidi Bojes,Varun Shetty,Elisabeth Burnor,Angela Rabe,Guinevere Ellison-Giles,Alexander T Yu,Austin Bell,Stephanie Meyer,Ruth Lynfield,Melissa Sutton,Ryan Scholz,Rebecca Falender,Shannon Matzinger,Allison Wheeler,Farah S Ahmed,John Anderson,Kate Harris,Austin Walkins,Surabhi Bohra,Victoria O'Dell,Virginia T Guidry,Ariel Christensen,Zack Moore,Erica Wilson,Joshua L Clayton,Hannah Parsons,Krista Kniss,Alicia Budd,Jeffrey W Mercante,Heather E Reese,Michael Welton,Megan Bias,Jenna Webb,Daniel Cornforth,Scott Santibañez,Rieza H Soelaeman,Manpreet Kaur,Amy E Kirby,John R Barnes,Nicole Fehrenbach,Sonja J Olsen,Margaret A Honein
{"title":"Wastewater Surveillance for Influenza A Virus and H5 Subtype Concurrent with the Highly Pathogenic Avian Influenza A(H5N1) Virus Outbreak in Cattle and Poultry and Associated Human Cases - United States, May 12-July 13, 2024.","authors":"Souci Louis,Miguella Mark-Carew,Matthew Biggerstaff,Jonathan Yoder,Alexandria B Boehm,Marlene K Wolfe,Matthew Flood,Susan Peters,Mary Grace Stobierski,Joseph Coyle,Matthew T Leslie,Mallory Sinner,Dawn Nims,Victoria Salinas,Layla Lustri,Heidi Bojes,Varun Shetty,Elisabeth Burnor,Angela Rabe,Guinevere Ellison-Giles,Alexander T Yu,Austin Bell,Stephanie Meyer,Ruth Lynfield,Melissa Sutton,Ryan Scholz,Rebecca Falender,Shannon Matzinger,Allison Wheeler,Farah S Ahmed,John Anderson,Kate Harris,Austin Walkins,Surabhi Bohra,Victoria O'Dell,Virginia T Guidry,Ariel Christensen,Zack Moore,Erica Wilson,Joshua L Clayton,Hannah Parsons,Krista Kniss,Alicia Budd,Jeffrey W Mercante,Heather E Reese,Michael Welton,Megan Bias,Jenna Webb,Daniel Cornforth,Scott Santibañez,Rieza H Soelaeman,Manpreet Kaur,Amy E Kirby,John R Barnes,Nicole Fehrenbach,Sonja J Olsen,Margaret A Honein","doi":"10.15585/mmwr.mm7337a1","DOIUrl":"https://doi.org/10.15585/mmwr.mm7337a1","url":null,"abstract":"As part of the response to the highly pathogenic avian influenza A(H5N1) virus outbreak in U.S. cattle and poultry and the associated human cases, CDC and partners are monitoring influenza A virus levels and detection of the H5 subtype in wastewater. Among 48 states and the District of Columbia that performed influenza A testing of wastewater during May 12-July 13, 2024, a weekly average of 309 sites in 38 states had sufficient data for analysis, and 11 sites in four states reported high levels of influenza A virus. H5 subtype testing was conducted at 203 sites in 41 states, with H5 detections at 24 sites in nine states. For each detection or high level, CDC and state and local health departments evaluated data from other influenza surveillance systems and partnered with wastewater utilities and agriculture departments to investigate potential sources. Among the four states with high influenza A virus levels detected in wastewater, three states had corresponding evidence of human influenza activity from other influenza surveillance systems. Among the 24 sites with H5 detections, 15 identified animal sources within the sewershed or adjacent county, including eight milk-processing inputs. Data from these early investigations can help health officials optimize the use of wastewater surveillance during the upcoming respiratory illness season.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"63 1","pages":"804-809"},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142273374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Linda Beer,Yunfeng Tie,Stacy M Crim,John Weiser,Jennifer Taussig,Jason A Craw,Kate A Buchacz,Ashanté Dobbs,Charles B Collins,Marie E Johnston,Andrew De Los Reyes,Deborah Gelaude,Kamal Hughes,Rodel Desamu-Thorpe,Joseph Prejean
{"title":"Progress Toward Achieving National HIV/AIDS Strategy Goals for Quality of Life Among Persons Aged ≥50 Years with Diagnosed HIV - Medical Monitoring Project, United States, 2017-2023.","authors":"Linda Beer,Yunfeng Tie,Stacy M Crim,John Weiser,Jennifer Taussig,Jason A Craw,Kate A Buchacz,Ashanté Dobbs,Charles B Collins,Marie E Johnston,Andrew De Los Reyes,Deborah Gelaude,Kamal Hughes,Rodel Desamu-Thorpe,Joseph Prejean","doi":"10.15585/mmwr.mm7336a1","DOIUrl":"https://doi.org/10.15585/mmwr.mm7336a1","url":null,"abstract":"Ensuring good quality of life (QoL) among persons with diagnosed HIV (PWH) is a priority of the National HIV/AIDS Strategy (NHAS), which established 2025 goals for improving QoL. Goals are monitored through five indicators: self-rated health, unmet needs for mental health services, unemployment, hunger or food insecurity, and unstable housing or homelessness. Among the growing population of PWH aged ≥50 years, progress toward these goals has not been assessed. Data collected during the 2017-2022 cycles of the Medical Monitoring Project, an annual complex sample survey of U.S. adults with diagnosed HIV, assessed progress toward NHAS 2025 QoL goals among PWH aged ≥50 years, overall and by age group. The recent estimated annual percentage change from baseline (2017 or 2018) to 2022 was calculated for each indicator. Among PWH aged ≥50 years, the 2025 goal of 95% PWH with good or better self-rated health is 46.2% higher than the 2022 estimate. The 2025 goals of a 50% reduction in the other indicators range from 26.3% to 56.3% lower than the 2022 estimates. Decreasing hunger or food insecurity by 50% among PWH aged ≥65 was the only goal met by 2022. If recent trends continue, other NHAS QoL 2025 goals are unlikely to be met. Multisectoral strategies to improve access to housing, employment, food, and mental health will be needed to meet NHAS 2025 goals for QoL among older PWH.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"3 1","pages":"781-787"},"PeriodicalIF":0.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142231394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer P Collins,Jamie Loehr,Wilbur H Chen,Matthew Clark,Veronica Pinell-McNamara,Lucy A McNamara
{"title":"Use of Haemophilus influenzae Type b-Containing Vaccines Among American Indian and Alaska Native Infants: Updated Recommendations of the Advisory Committee on Immunization Practices - United States, 2024.","authors":"Jennifer P Collins,Jamie Loehr,Wilbur H Chen,Matthew Clark,Veronica Pinell-McNamara,Lucy A McNamara","doi":"10.15585/mmwr.mm7336a4","DOIUrl":"https://doi.org/10.15585/mmwr.mm7336a4","url":null,"abstract":"Invasive Haemophilus influenzae type b (Hib) disease is a serious bacterial infection that disproportionally affects American Indian and Alaska Native (AI/AN) populations. Hib vaccination with a monovalent Hib conjugate vaccine consisting of Hib capsular polysaccharide (polyribosylribitol phosphate [PRP]) conjugated to outer membrane protein complex of Neisseria meningitidis serogroup B, PRP-OMP (PedvaxHIB, Merck and Co., Inc.) has historically been preferred for AI/AN infants, who are at increased risk for invasive Hib disease, because it provides substantial protection after the first dose. On June 26, 2024, CDC's Advisory Committee on Immunization Practices (ACIP) recommended that a hexavalent, combined diphtheria and tetanus toxoids and acellular pertussis (DTaP), inactivated poliovirus (IPV), Hib conjugate, and hepatitis B (HepB) vaccine, DTaP-IPV-Hib-HepB (Vaxelis, MSP Vaccine Company) should be included with monovalent PRP-OMP in the preferential recommendation for AI/AN infants because of the PRP-OMP Hib component. A primary Hib vaccination series consisting of either 1) monovalent PRP-OMP (2-dose series at ages 2 and 4 months) or 2) DTaP-IPV-Hib-HepB (3-dose series at ages 2, 4, and 6 months) is preferred for AI/AN infants. DTaP-IPV-Hib-HepB is only indicated for use in infants at ages 2, 4, and 6 months and should not be used for the booster doses of Hib, DTaP, or IPV vaccines. For the booster dose of Hib vaccine, no vaccine formulation is preferred for AI/AN children; any Hib vaccine (except DTaP-IPV-Hib-HepB) should be used. This report summarizes evidence considered for these recommendations and provides clinical guidance for the use of Hib-containing vaccines among AI/AN infants and children.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"2 1","pages":"799-802"},"PeriodicalIF":0.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142231393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miwako Kobayashi,Andrew J Leidner,Ryan Gierke,Jennifer L Farrar,Rebecca L Morgan,Doug Campos-Outcalt,Robert Schechter,Katherine A Poehling,Sarah S Long,Jamie Loehr,Adam L Cohen
{"title":"Use of 21-Valent Pneumococcal Conjugate Vaccine Among U.S. Adults: Recommendations of the Advisory Committee on Immunization Practices - United States, 2024.","authors":"Miwako Kobayashi,Andrew J Leidner,Ryan Gierke,Jennifer L Farrar,Rebecca L Morgan,Doug Campos-Outcalt,Robert Schechter,Katherine A Poehling,Sarah S Long,Jamie Loehr,Adam L Cohen","doi":"10.15585/mmwr.mm7336a3","DOIUrl":"https://doi.org/10.15585/mmwr.mm7336a3","url":null,"abstract":"On June 17, 2024, the Food and Drug Administration approved 21-valent pneumococcal conjugate vaccine (PCV) (PCV21; CAPVAXIVE; Merck Sharp & Dohme, LLC) for adults aged ≥18 years. PCV21 does not contain certain serotypes that are included in other licensed pneumococcal vaccines but adds eight new serotypes. The Advisory Committee on Immunization Practices (ACIP) recommends use of a PCV for all adults aged ≥65 years, as well as adults aged 19-64 years with certain risk conditions for pneumococcal disease if they have not received a PCV or whose vaccination history is unknown. Previously, options included either 20-valent PCV (PCV20; Prevnar20; Wyeth Pharmaceuticals, Inc.) alone or a 15-valent PCV (PCV15; VAXNEUVANCE; Merck Sharp & Dohme, LLC) in series with 23-valent pneumococcal polysaccharide vaccine (PPSV23; Pneumovax23; Merck Sharp & Dohme, LLC). Additional recommendations for use of PCV20 exist for adults who started their pneumococcal vaccination series with 13-valent PCV (PCV13; Prevnar13; Wyeth Pharmaceuticals, Inc.). The ACIP Pneumococcal Vaccines Work Group employed the Evidence to Recommendations framework to guide its deliberations on PCV21 vaccination among U.S. adults. On June 27, 2024, ACIP recommended a single dose of PCV21 as an option for adults aged ≥19 years for whom PCV is currently recommended. Indications for PCV have not changed from previous recommendations. This report summarizes evidence considered for these recommendations and provides clinical guidance for use of PCV21.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":"62 1","pages":"793-798"},"PeriodicalIF":0.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142231392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Vaidyanathan, Abigail Gates, Claudia Brown, Emily Prezzato, Aaron Bernstein
{"title":"Heat-Related Emergency Department Visits — United States, May–September 2023","authors":"A. Vaidyanathan, Abigail Gates, Claudia Brown, Emily Prezzato, Aaron Bernstein","doi":"10.15585/mmwr.mm7315a1","DOIUrl":"https://doi.org/10.15585/mmwr.mm7315a1","url":null,"abstract":"Unprecedented heat waves can affect all persons, but some are more sensitive to the effects of heat, including children and adults with underlying health conditions, pregnant women, and outdoor workers. Many regions of the United States experienced record-breaking high temperatures in 2023, with populations exposed to extremely high temperatures for prolonged periods. CDC examined emergency department (ED) visits associated with heat-related illness (HRI) from the National Syndromic Surveillance Program and compared daily HRI ED visit rates during the warm-season months (May-September) of 2023 with those during 2018-2022. In the 2023 warm-season months, daily HRI ED visit rates peaked in several regions and remained elevated for a prolonged duration. More males than females sought care in EDs for HRI, especially males aged 18-64 years. CDC issued multiple public health alerts using the Epidemic Information Exchange system to bring attention to increases in ED utilization for HRI. Deaths and illnesses associated with heat exposure are a continuing public health concern as climate change results in longer, hotter, and more frequent episodes of extreme heat. Near real-time monitoring of weather conditions and adverse health outcomes can guide public health practitioners' timing of risk communication and implementation of prevention measures associated with extreme heat.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":" 5","pages":"324 - 329"},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140687589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Franklin, Kira Barbre, Theresa Rowe, Hannah Reses, Jason Massey, Lu Meng, Philip Dollard, Heather Dubendris, Molly Stillions, Lindsay Robinson, Jacques W Clerville, K. J. Slifka, Andrea Benin, Jeneita Bell
{"title":"COVID-19 Vaccination Coverage, and Rates of SARS-CoV-2 Infection and COVID-19–Associated Hospitalization Among Residents in Nursing Homes — National Healthcare Safety Network, United States, October 2023–February 2024","authors":"David Franklin, Kira Barbre, Theresa Rowe, Hannah Reses, Jason Massey, Lu Meng, Philip Dollard, Heather Dubendris, Molly Stillions, Lindsay Robinson, Jacques W Clerville, K. J. Slifka, Andrea Benin, Jeneita Bell","doi":"10.15585/mmwr.mm7315a3","DOIUrl":"https://doi.org/10.15585/mmwr.mm7315a3","url":null,"abstract":"Nursing home residents are at increased risk for developing severe COVID-19. Nursing homes report weekly facility-level data on SARS-CoV-2 infections, COVID-19-associated hospitalizations, and COVID-19 vaccination coverage among residents to CDC's National Healthcare Safety Network. This analysis describes rates of incident SARS-CoV-2 infection, rates of incident COVID-19-associated hospitalization, and COVID-19 vaccination coverage during October 16, 2023-February 11, 2024. Weekly rates of SARS-CoV-2 infection ranged from 61.4 to 133.8 per 10,000 nursing home residents. The weekly percentage of facilities reporting one or more incident SARS-CoV-2 infections ranged from 14.9% to 26.1%. Weekly rates of COVID-19-associated hospitalization ranged from 3.8 to 7.1 per 10,000 residents, and the weekly percentage of facilities reporting one or more COVID-19-associated hospitalizations ranged from 2.6% to 4.7%. By February 11, 2024, 40.5% of nursing home residents had received a dose of the updated 2023-2024 COVID-19 vaccine that was first recommended in September 2023. Although the peak rate of SARS-CoV-2 infection among nursing home residents was lower during the 2023-24 respiratory virus season than during the three previous respiratory virus seasons, nursing home residents continued to be disproportionately affected by SARS-CoV-2 infection and related severe outcomes. Vaccination coverage remains suboptimal in this population. Ongoing surveillance for SARS-CoV-2 infections and COVID-19-associated hospitalizations in this population is necessary to develop and evaluate evidence-based interventions for protecting nursing home residents.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":" 2","pages":"339 - 344"},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140688550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer P Collins, Samuel J Crowe, Ismael R. Ortega-Sanchez, Lynn Bahta, Doug Campos-Outcalt, Jamie Loehr, Rebecca L Morgan, K. Poehling, Lucy A McNamara
{"title":"Use of the Pfizer Pentavalent Meningococcal Vaccine Among Persons Aged ≥10 Years: Recommendations of the Advisory Committee on Immunization Practices ― United States, 2023","authors":"Jennifer P Collins, Samuel J Crowe, Ismael R. Ortega-Sanchez, Lynn Bahta, Doug Campos-Outcalt, Jamie Loehr, Rebecca L Morgan, K. Poehling, Lucy A McNamara","doi":"10.15585/mmwr.mm7315a4","DOIUrl":"https://doi.org/10.15585/mmwr.mm7315a4","url":null,"abstract":"Meningococcal disease is a life-threatening invasive infection caused by Neisseria meningitidis. Two quadrivalent (serogroups A, C, W, and Y) meningococcal conjugate vaccines (MenACWY) (MenACWY-CRM [Menveo, GSK] and MenACWY-TT [MenQuadfi, Sanofi Pasteur]) and two serogroup B meningococcal vaccines (MenB) (MenB-4C [Bexsero, GSK] and MenB-FHbp [Trumenba, Pfizer Inc.]), are licensed and available in the United States and have been recommended by CDC's Advisory Committee on Immunization Practices (ACIP). On October 20, 2023, the Food and Drug Administration approved the use of a pentavalent meningococcal vaccine (MenACWY-TT/MenB-FHbp [Penbraya, Pfizer Inc.]) for prevention of invasive disease caused by N. meningitidis serogroups A, B, C, W, and Y among persons aged 10-25 years. On October 25, 2023, ACIP recommended that MenACWY-TT/MenB-FHbp may be used when both MenACWY and MenB are indicated at the same visit for the following groups: 1) healthy persons aged 16-23 years (routine schedule) when shared clinical decision-making favors administration of MenB vaccine, and 2) persons aged ≥10 years who are at increased risk for meningococcal disease (e.g., because of persistent complement deficiencies, complement inhibitor use, or functional or anatomic asplenia). Different manufacturers' serogroup B-containing vaccines are not interchangeable; therefore, when MenACWY-TT/MenB-FHbp is used, subsequent doses of MenB should be from the same manufacturer (Pfizer Inc.). This report summarizes evidence considered for these recommendations and provides clinical guidance for the use of MenACWY-TT/MenB-FHbp.","PeriodicalId":18931,"journal":{"name":"Morbidity and Mortality Weekly Report","volume":" 45","pages":"345 - 350"},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140687546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}