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Isomeric oxabenzochrysenones from Musa acuminata and Wachendorfia thyrsiflora. 荆芥和荆芥的异分异构体草苯并蒽酮。
Natural Product Letters Pub Date : 2002-10-01 DOI: 10.1080/10575630290033079
Stefan Opitz, Felipe Otálvaro, Fernando Echeverri, Winston Quiñones, Bernd Schneider
{"title":"Isomeric oxabenzochrysenones from Musa acuminata and Wachendorfia thyrsiflora.","authors":"Stefan Opitz,&nbsp;Felipe Otálvaro,&nbsp;Fernando Echeverri,&nbsp;Winston Quiñones,&nbsp;Bernd Schneider","doi":"10.1080/10575630290033079","DOIUrl":"https://doi.org/10.1080/10575630290033079","url":null,"abstract":"<p><p>Two new oxabenzochrysenones (naphthoxanthenones), representing phenylphenalenone-related natural products, were isolated from Musa acuminata and Wachendorfia thyrsiflora.</p>","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"16 5","pages":"335-8"},"PeriodicalIF":0.0,"publicationDate":"2002-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10575630290033079","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22115305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
New Triterpenoids from the Orchids Scaphyglottis Livida and Nidema Boothii 兰科植物黄花兰科植物和凤仙花兰科植物的新三萜类化合物
Natural Product Letters Pub Date : 2002-01-01 DOI: 10.1080/10575630290019967
S. Estrada, L. Acevedo, Mitzi Rodriguez, R. Toscano, R. Mata
{"title":"New Triterpenoids from the Orchids Scaphyglottis Livida and Nidema Boothii","authors":"S. Estrada, L. Acevedo, Mitzi Rodriguez, R. Toscano, R. Mata","doi":"10.1080/10575630290019967","DOIUrl":"https://doi.org/10.1080/10575630290019967","url":null,"abstract":"Two new triterpenoids, nidemin ( 1 ), a modified lanostane, and 9,19-cyclolanosta-24,24-dimethyl-25-en-3 -yl trans - p -hydroxycinnamate ( 2 ) have been isolated from the orchids Nidema boothii and Scaphyglottis livida , respectively. The isolates were characterized by spectral methods. The structure of nidemin ( 1 ) was unambiguously confirmed by X-ray analysis.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"23 1","pages":"81 - 86"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73757128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
An in vitro screening method for DNA cytosine-C5-methylase inhibitor DNA胞嘧啶- c5 -甲基化酶抑制剂的体外筛选方法
Natural Product Letters Pub Date : 2002-01-01 DOI: 10.1080/1057563029001/4809
T. Tamura, Atsushi Kataoka, Lidan Shu, Akihiko Ashida, Hidehiko Tanaka, K. Inagaki
{"title":"An in vitro screening method for DNA cytosine-C5-methylase inhibitor","authors":"T. Tamura, Atsushi Kataoka, Lidan Shu, Akihiko Ashida, Hidehiko Tanaka, K. Inagaki","doi":"10.1080/1057563029001/4809","DOIUrl":"https://doi.org/10.1080/1057563029001/4809","url":null,"abstract":"A specific inhibitor of DNA cytosine C5-methylases would be useful for studying genomic imprinting, X-chromosome inactivation, carcinogenesis, and regulation of tissue-specific gene expression, for these physiological phenomena appears to be regulated through DNA methylation in promoter sequences. This paper reports a novel convenient in vitro assay method for screening DNA cytosine C5-methylase inhibitor. Our method uses a commercially available Hae III methylase (cytosine C5 methylase), its corresponding Hae III endonuclease, and u DNA as their substrate.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"606 1","pages":"25 - 27"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77468957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Two New Cyclic Bis(Bibenzyl)s, Isoriccardinquinone A and B from the Liverwort Marchantia Paleacea 两个新环双(联苯基)s，异烟基红醌A和B
Natural Product Letters Pub Date : 2002-01-01 DOI: 10.1080/10575630290004242
M. So, W. Chan, P. Xia, Yu-xin Cui
{"title":"Two New Cyclic Bis(Bibenzyl)s, Isoriccardinquinone A and B from the Liverwort Marchantia Paleacea","authors":"M. So, W. Chan, P. Xia, Yu-xin Cui","doi":"10.1080/10575630290004242","DOIUrl":"https://doi.org/10.1080/10575630290004242","url":null,"abstract":"From the 95% ethanol extract of the Hong Kong liverwort, Marchantia paleacea , guided by bioactivity directed isolation, two novel isoriccardinquinones A and B were obtained together with previously known marchantin C, isoriccardin C and phenanthrene derivative, 2-hydroxy-3,7-dimethoxyphenanthrene. The structures of the new compounds were established by high field spectroscopic methods, including 2D NMR techniques.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"192 1","pages":"167 - 171"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78031050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Extraction Studies of Tabernanthe Iboga and Voacanga Africana 山核桃和非洲山核桃的提取研究
Natural Product Letters Pub Date : 2002-01-01 DOI: 10.1080/1057563029001/4881
Christopher Jenks
{"title":"Extraction Studies of Tabernanthe Iboga and Voacanga Africana","authors":"Christopher Jenks","doi":"10.1080/1057563029001/4881","DOIUrl":"https://doi.org/10.1080/1057563029001/4881","url":null,"abstract":"The root bark of Tabernanthe iboga contains ibogaine as its predominant alkaloid and has been an important source of it. Ibogaine is used experimentally to interrupt drug addiction and allow therapeutic intervention, but is currently unaffordable to doctors in less economically developed countries. To meet this need, an extraction of alkaloids from T. iboga root bark was optimized and simplified to use only diluted vinegar and ammonia, and was successfully applied to related alkaloids from Voacanga africana bark also. The alkaloids were converted to their hydrochlorides and purified, and the minor alkaloids were recovered.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"27 15 1","pages":"71 - 76"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78645750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 44
Marruboside, a New Phenylethanoid Glycoside from Marrubium Vulgare L 一种来自凡士林的新型苯乙醇苷
Natural Product Letters Pub Date : 2002-01-01 DOI: 10.1080/10575630290013576
S. Sahpaz, T. Hennebelle, F. Bailleul
{"title":"Marruboside, a New Phenylethanoid Glycoside from Marrubium Vulgare L","authors":"S. Sahpaz, T. Hennebelle, F. Bailleul","doi":"10.1080/10575630290013576","DOIUrl":"https://doi.org/10.1080/10575630290013576","url":null,"abstract":"A new phenylethanoid glycoside, marruboside, has been isolated from the aerial parts of Marrubium vulgare L. Its structure was established as 3,4-dihydroxy- g -phenylethoxy- O- [ g - d -apiofuranosyl-(1 M 2)- f - l -rhamnopyranosyl-(1 M 3)]-[ g - d -apiofuranosyl-(1 M 6)]-4- O -caffeoyl- g - d -glucopyranoside, on the basis of spectroscopic evidence.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"45 1","pages":"195 - 199"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87900684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
New Triterpenoids from the Leaves of Abrus Precatorius 标题青花蒿叶中的新三萜类化合物
Natural Product Letters Pub Date : 2002-01-01 DOI: 10.1080/10575630290020596
Nam-Cheol Kim, Darrick S. H. L. Kim, A. Kinghorn
{"title":"New Triterpenoids from the Leaves of Abrus Precatorius","authors":"Nam-Cheol Kim, Darrick S. H. L. Kim, A. Kinghorn","doi":"10.1080/10575630290020596","DOIUrl":"https://doi.org/10.1080/10575630290020596","url":null,"abstract":"Three new ( 1-3 ) triterpenoids and one known ( 4 ) triterpenoid were isolated from an acid hydrolyzed methanol-soluble extract of the leaves of Abrus precatorius . Their structures were identified as (20 S ,22 S )-3 g ,22-dihydroxycucurbita-5(10),24-diene-26,29-dioic acid i -lactone ( 1 ), 3- O -[6'-methyl- g - d -glucuronopyranosyl]-3 g ,22 g -dihydroxyolean-12-en-29-oic acid methyl ester ( 2 ), 3- O - g - d -glucuronopyranosylsophoradiol methyl ester ( 3 ), and sophoradiol ( 4 ) by spectroscopic techniques including 2D NMR.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"3 1","pages":"261 - 266"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86392576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 22
A New Approach for Asymmetric Synthesis of (R)-3-Methylpyrrolidine Alkaloids from (S)-Malic Acid (S)-苹果酸不对称合成(R)-3-甲基吡咯烷生物碱的新方法
Natural Product Letters Pub Date : 2002-01-01 DOI: 10.1080/1057563029001/4854
Xiao Zheng, Pei‐Qiang Huang, Yuanping Ruan, A. Lee, W. Chan
{"title":"A New Approach for Asymmetric Synthesis of (R)-3-Methylpyrrolidine Alkaloids from (S)-Malic Acid","authors":"Xiao Zheng, Pei‐Qiang Huang, Yuanping Ruan, A. Lee, W. Chan","doi":"10.1080/1057563029001/4854","DOIUrl":"https://doi.org/10.1080/1057563029001/4854","url":null,"abstract":"Diastereoselective methylation of dimethyl (S)-malate 7, followed by two, three-step reductive de-hydroxylation procedures afforded dimethyl (R)-2-methylsuccinate 11 in 80.2% e.e. and 84.7% e.e., respectively. The latter compound was further transformed into the natural enantiomers of the ant venom alkaloids (R)-leptothoracine 1 and (R)-3-methyl-N-(2-phenylethyl)-pyrrolidine 2.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"44 1","pages":"53 - 56"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79706951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
A Novel Cacalolide from Psacalium Decompositum 一种新的仙人掌碱类化合物
Natural Product Letters Pub Date : 2002-01-01 DOI: 10.1080/10575630290020532
R. Reyes‐Chilpa, M. Jiménez-Estrada, Marcia V Godínez, S. Hernández-Ortega, M. Campos, E. Bejar
{"title":"A Novel Cacalolide from Psacalium Decompositum","authors":"R. Reyes‐Chilpa, M. Jiménez-Estrada, Marcia V Godínez, S. Hernández-Ortega, M. Campos, E. Bejar","doi":"10.1080/10575630290020532","DOIUrl":"https://doi.org/10.1080/10575630290020532","url":null,"abstract":"A new cacalolide sesquiterpenoid, named as Romo-A, was isolated from the roots of Psacalium decompositum , Asteraceae, a Mexican medicinal shrub with antidiabetic properties. Its structure was elucidated by NMR, MS, IR, UV, and confirmed by X-ray diffraction studies.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"102 12 1","pages":"239 - 242"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88749976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A Novel Phenanthrenolide and C-Benzyl Dihydrochalcones from Uvaria Puguensis 普古乌耳草中一种新的菲蒽酚内酯和c -苄基二氢查尔酮
Natural Product Letters Pub Date : 2002-01-01 DOI: 10.1080/10575630290020604
J. Makangara, S. Jonker, M. Nkunya
{"title":"A Novel Phenanthrenolide and C-Benzyl Dihydrochalcones from Uvaria Puguensis","authors":"J. Makangara, S. Jonker, M. Nkunya","doi":"10.1080/10575630290020604","DOIUrl":"https://doi.org/10.1080/10575630290020604","url":null,"abstract":"Two new natural products, the phenanthrenoid puguenolide (6-hydroxy-3-methoxy-4-oxapyren-5-one) and isoangoletin were isolated from the stem bark of the newly described Uvaria species, U. puguensis D.M. Johnson, together with the sesquiterpene guaiol and the usual C-benzyldihydrochalcones previously found in the genus Uvaria , viz . uvaretin, diuvaretin, chamuvaritin and a mixture of triuvaretin and isotriuvaretin. Structural elucidation was achieved through a combination of spectroscopic methods.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"76 1","pages":"267 - 272"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75157649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
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