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Metabolites from Fungi 15. New Isocoumarins from an Endophytic Fungus Isolated from the Canadian Thistle Cirsium arvense 真菌的代谢物加拿大蓟内生真菌中新的异香豆素
Natural Product Letters Pub Date : 2001-11-01 DOI: 10.1080/10575630108041303
K. Krohn, U. Flörke, M. S. Rao, K. Steingröver, H. Aust, S. Draeger, B. Schulz
{"title":"Metabolites from Fungi 15. New Isocoumarins from an Endophytic Fungus Isolated from the Canadian Thistle Cirsium arvense","authors":"K. Krohn, U. Flörke, M. S. Rao, K. Steingröver, H. Aust, S. Draeger, B. Schulz","doi":"10.1080/10575630108041303","DOIUrl":"https://doi.org/10.1080/10575630108041303","url":null,"abstract":"Abstract One known (1) and five new polyketide metabolites (2-6) were isolated from the culture extract of an endophytic fungus. Mycelia sterila, from the Canadian thistle Cirsium arvense. Compounds 1-4 are members of the isocoumarin family, whereas metabolite 5 is a dihydrobenzofuran and 6 has an open chain structure. All compounds have an unusual methyl group at the aromatic ring that does not fit into the usual polyketide pattern.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"444 1","pages":"353 - 361"},"PeriodicalIF":0.0,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84899667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 51
New Galactolipids from the Marine Bacillariophycean Microalga Nitzschia sp 海洋硅藻微藻Nitzschia sp .的新半乳糖脂
Natural Product Letters Pub Date : 2001-11-01 DOI: 10.1080/10575630108041296
B. Son, Yong‐Jin Cho, J. Choi, W. Lee, Dong-Soo Kim, H. Choi, Jae-Sue Choi, Jee H Jung, K. Im, W. C. Choi
{"title":"New Galactolipids from the Marine Bacillariophycean Microalga Nitzschia sp","authors":"B. Son, Yong‐Jin Cho, J. Choi, W. Lee, Dong-Soo Kim, H. Choi, Jae-Sue Choi, Jee H Jung, K. Im, W. C. Choi","doi":"10.1080/10575630108041296","DOIUrl":"https://doi.org/10.1080/10575630108041296","url":null,"abstract":"Abstract Two new galactopyranosyldiacylglycerols have been isolated from the marine baciilariophycean microalga Nizschia sp. and their structures were determined as (2S)-3-O-β-D-galactopyranosyl-1,2-di-O-(9Z-hexadecenoyl)glycerol (1) and (2S)-3-O-β-D-galactopyranosyl-1,O-(5Z, 8Z,11Z.14Z,17Z-eicosapentaenoyl)-2-O-(9Z-hexadecenoyl)glycerol (2) by physicochemical evidence.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"2 1","pages":"299 - 306"},"PeriodicalIF":0.0,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88210454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Short Synthesis of Novel 9,11-Secosterols 新型9,11-二醇类化合物的短合成
Natural Product Letters Pub Date : 2001-10-01 DOI: 10.1080/10575630108041285
R. Jäälaid, I. Järving, T. Pehk, O. Parve, Ü. Lille
{"title":"Short Synthesis of Novel 9,11-Secosterols","authors":"R. Jäälaid, I. Järving, T. Pehk, O. Parve, Ü. Lille","doi":"10.1080/10575630108041285","DOIUrl":"https://doi.org/10.1080/10575630108041285","url":null,"abstract":"Abstract Starting from ergosterol two novel 9,11-secosterols with modified side chains (1a) and (1c) were synthesized via eight main transformations.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"20 1","pages":"221 - 228"},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89091358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Characterization of a New Decahydropyridoquinoline from Indigofera longeracemosa Boiv. Ex Baill. (Fabaceae) 一种新型十氢吡啶喹啉的表征。Baill交货。(豆科)
Natural Product Letters Pub Date : 2001-10-01 DOI: 10.1080/10575630108041293
D. Thangadurai, M. Viswanathan, N. Ramesh
{"title":"Characterization of a New Decahydropyridoquinoline from Indigofera longeracemosa Boiv. Ex Baill. (Fabaceae)","authors":"D. Thangadurai, M. Viswanathan, N. Ramesh","doi":"10.1080/10575630108041293","DOIUrl":"https://doi.org/10.1080/10575630108041293","url":null,"abstract":"Repeated silica gel chromatography of the dichloromethane extract of air-dried stems of Indigofera longeracemosa followed by reverse-phase HPLC separation yielded a new decahydropyridoquinoline, rel-(3S, 5R, 6S, SR, 8aR, 12aR)-8-acetoxy-6-butyl-3-isothiocyanatodecahydropyrido (2,1) quinoline.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"C-18 1","pages":"287 - 290"},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85049110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Editorial board page for “Natural Product Letters”, Volume 15, Number 4 编辑委员会页“天然产品信函”，卷15，第4号
Natural Product Letters Pub Date : 2001-10-01 DOI: 10.1080/10575630108041282
{"title":"Editorial board page for “Natural Product Letters”, Volume 15, Number 4","authors":"","doi":"10.1080/10575630108041282","DOIUrl":"https://doi.org/10.1080/10575630108041282","url":null,"abstract":"Abstract This is a scanned image of the original Editorial Board page(s) for this issue.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"148 1","pages":"a - a"},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73036284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytotoxic Hydroxyanthracenones from Fruits of Karwinskia Parvifolia 小檗果实中的细胞毒性羟基蒽酮
Natural Product Letters Pub Date : 2001-10-01 DOI: 10.1080/10575630108041288
V. R. Galindo, N. Waksman
{"title":"Cytotoxic Hydroxyanthracenones from Fruits of Karwinskia Parvifolia","authors":"V. R. Galindo, N. Waksman","doi":"10.1080/10575630108041288","DOIUrl":"https://doi.org/10.1080/10575630108041288","url":null,"abstract":"Abstract Peroxisomicines A1 (1) and A2 (2) are cytotoxic hydroxyanthracenones isolated from the fruits of Karwinskia parvifolia. Peroxisomicine A1 exhibits selective cytotoxicity against several tumor cell lines. In the present investigation three minor constituents were obtained from the same fruit extracts; peroxisomicine A3 (3) and isoperoxisomicines A1 (4) and A2 (5). Compounds 3and 5 are novel and their structures were determined by spectroscopic methods and molecular modeling. Compounds 1-5 were significantly cytotoxic against hepatoma cell lines.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"15 1","pages":"243 - 251"},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78768757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Bowdenol, a New 2,3-Dihydrobenzofuran Constituent from Bowdichia Virgilioides 鲍登酚:一种新的2,3-二氢苯并呋喃化合物
Natural Product Letters Pub Date : 2001-10-01 DOI: 10.1080/10575630108041290
Francisca N. Melo, V. Navarro, M. S. Silva, Emidio V. Leitão da‐Cunha, J. Barbosa-Filho, R. Braz-Filho
{"title":"Bowdenol, a New 2,3-Dihydrobenzofuran Constituent from Bowdichia Virgilioides","authors":"Francisca N. Melo, V. Navarro, M. S. Silva, Emidio V. Leitão da‐Cunha, J. Barbosa-Filho, R. Braz-Filho","doi":"10.1080/10575630108041290","DOIUrl":"https://doi.org/10.1080/10575630108041290","url":null,"abstract":"Abstract From the stem bark of Bowdichia virgilioides, lupeol, lupeol acetate, sitosterol, stigmasterol and methyl-3-[2-(1-hydroxymethylvinyl)2,3-dihydrobenzo[b]furan-5-yl]-(E)-2-propenoate have been isolated. The latter is a new compound and it has been named as bowdenol. Their structures were elucidated with the aid of spectroscopic techniques, mostly 1 and 2D NMR. The biogenetic pathway for bowdenol has been suggested.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"89 1","pages":"261 - 266"},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72812344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
N2,N2 , 7-Trimethylguanine, a New Trimethylated Guanine Natural Product from the New Zealand Ascidian, Lissoclinum Notti N2,N2, 7-三甲基鸟嘌呤，一种新的三甲基鸟嘌呤天然产物，来自新西兰海鞘，Lissoclinum Notti
Natural Product Letters Pub Date : 2001-10-01 DOI: 10.1080/10575630108041287
A. Pearce, Russell C. Babcock, G. Lambert, B. Copp
{"title":"N2,N2 , 7-Trimethylguanine, a New Trimethylated Guanine Natural Product from the New Zealand Ascidian, Lissoclinum Notti","authors":"A. Pearce, Russell C. Babcock, G. Lambert, B. Copp","doi":"10.1080/10575630108041287","DOIUrl":"https://doi.org/10.1080/10575630108041287","url":null,"abstract":"Abstract From the New Zealand ascidian, Lissoclinum notti a new natural product, N2,N2 , 7-trimethyl-guanine (1) has been isolated. The structure of 1 was elucidated by analysis of spectroscopic data.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"128 1","pages":"237 - 241"},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79221443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
New Antifeedant Triterpene Glycosides from the Caribbean Sponge Erylus Formosus 从加勒比海绵中提取的新的抗食性三萜苷
Natural Product Letters Pub Date : 2001-10-01 DOI: 10.1080/10575630108041292
J. Kubanek, W. Fenical, J. Pawlik
{"title":"New Antifeedant Triterpene Glycosides from the Caribbean Sponge Erylus Formosus","authors":"J. Kubanek, W. Fenical, J. Pawlik","doi":"10.1080/10575630108041292","DOIUrl":"https://doi.org/10.1080/10575630108041292","url":null,"abstract":"Abstract Two groups of antifeedant triterpene glycosides were identified from the Caribbean sponge Erylus formosus. The structure of formoside B, a novel N-acetyl amino derivative of the known penasterol tetrasaccharide formoside, was elucidated using NMR and mass spectral data. Four triterpene hexasaccharides and two triterpene trisaccharides, characterized by a 31-carbon aglycone, proved difficult to isolate and therefore only the structure of their aglycone was determined. Gas chromatographic analysis of derivatized saccharides from these mixtures established the carbohydrate content of these compounds. All of the triterpene glycosides isolated contributed to the chemical defenses of this sponge, although with differing activities.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"1 1","pages":"275 - 285"},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88279835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Enhanced Podophyllotoxin Production from Agrobacterium Rhizogenes Transformed Cultures of Podophyllum Hexandrum 根状农杆菌转化六足鬼臼培养物提高鬼臼毒素产量的研究
Natural Product Letters Pub Date : 2001-10-01 DOI: 10.1080/10575630108041286
A. Giri, C. C. Giri, V. Dhingra, M. Narasu
{"title":"Enhanced Podophyllotoxin Production from Agrobacterium Rhizogenes Transformed Cultures of Podophyllum Hexandrum","authors":"A. Giri, C. C. Giri, V. Dhingra, M. Narasu","doi":"10.1080/10575630108041286","DOIUrl":"https://doi.org/10.1080/10575630108041286","url":null,"abstract":"Abstract Podophyllotoxin, a potent chemotherapeutic agent is obtained from Podophylhum hexandrum Royle. Embryos of P. hexandrum were transformed using different strains of Agrobacterium rhizogenes viz. A4, 15834, K599. Transformed nature of the calli was ascertained and the cultures were further maintained as individual clones. HPLC analysis of transformed cultures depicted a three-fold increase in podophyllotoxin content in comparison to controls.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"19 1","pages":"229 - 235"},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75586814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 46
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