Martha A. Brumfield, Graham C. Higson, Cécile Ollivier, Nathalie Seigneuret
{"title":"Delivering regulatory impact from consortium-based projects","authors":"Martha A. Brumfield, Graham C. Higson, Cécile Ollivier, Nathalie Seigneuret","doi":"10.1038/d41573-025-00098-8","DOIUrl":"https://doi.org/10.1038/d41573-025-00098-8","url":null,"abstract":"Multiple consortia have been established in the past two decades with the aim of tackling roadblocks in the development of medical products, often by developing new tools to support decision making by regulatory agencies. Here, we highlight lessons learned from these efforts that could help maximize the regulatory impact of consortium-based projects.","PeriodicalId":18847,"journal":{"name":"Nature Reviews Drug Discovery","volume":"90 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144237901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Accelerating precision oncology by converging pragmatic trials and real-world evidence","authors":"Kjetil Taskén, Piers Mahon","doi":"10.1038/d41573-025-00047-5","DOIUrl":"https://doi.org/10.1038/d41573-025-00047-5","url":null,"abstract":"Engaging sufficient numbers of patients with cancers that have particular molecular characteristics is a key challenge in building evidence to support precision medicine in oncology. These challenges could be addressed by converging pragmatic clinical trials and hospital cancer informatics infrastructures to integrate cancer care and research.","PeriodicalId":18847,"journal":{"name":"Nature Reviews Drug Discovery","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143608392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
求助内容：
应助结果提醒方式：