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Comparative histopathology of Dactylaria constricta, Fonsecaea pedrosoi, Wangiella dermatitidis, and Xylohypha bantiana in experimental phaeohyphomycosis of the central nervous system. 中枢神经系统实验性褐丝酵母菌病中缢缩短尾菌、木癣菌、皮炎王氏菌和班提亚木菌丝的比较组织病理学研究。
Mykosen Pub Date : 1987-05-01 DOI: 10.1111/j.1439-0507.1987.tb03970.x
T J Walsh, D M Dixon, A Polak, I F Salkin
{"title":"Comparative histopathology of Dactylaria constricta, Fonsecaea pedrosoi, Wangiella dermatitidis, and Xylohypha bantiana in experimental phaeohyphomycosis of the central nervous system.","authors":"T J Walsh, D M Dixon, A Polak, I F Salkin","doi":"10.1111/j.1439-0507.1987.tb03970.x","DOIUrl":"https://doi.org/10.1111/j.1439-0507.1987.tb03970.x","url":null,"abstract":"Summary: The comparative neuropathology of experimental phaeohyphomycosis due to Dactylaria constricta (D. gallopava; Scolecobasidium constrictum), Fonsecaea pedrosoi, Wangiella dermatitidis (Exophiala dermatitidis), and Xylohypha bantiana cladosporium bantianum; C. trichoides), was studied in the mouse central nervous system (CNS). All fungi appeared as brown hyphae on hematoxylin and eosin stain. Zigzag forms of hyphae were common in all species except F. pedrosoi. Neither blastoconidia nor chlamydoconidia were present in tissue infected with D. constricta. D. constricta, W. dermatitidis, and X. bantiana were distributed hematogenously throughout the cerebral hemispheres and demonstrated intraluminal, microvascular invasion whereas, CNS infection due to F. pedrosoi developed by extension from extracerebral dural lesions. F. pedrosoi invaded small to medium‐sized cerebral arteries and veins by extraluminal extension. Microabscesses and early granuloma formation occurred with D. constricta, W. dermatitidis, and X. bantiana, but not with F. pedrosoi, which was associated with only scant cellular inflammatory reaction. Only D. constricta caused a necrotizing ventriculitis with periventricular hemorrhage. Other than yeast‐like cells in W. dermatitidis and F. pedrosoi, ventriculitis in D. constricta, and epidural invasion in F. pedrosoi, these infections are remarkably similar in tissue.","PeriodicalId":18826,"journal":{"name":"Mykosen","volume":"30 5","pages":"215-25"},"PeriodicalIF":0.0,"publicationDate":"1987-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb03970.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14735012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 31
Ultrastructural changes in pathogenic fungi treated in vitro with chlorpromazine. 氯丙嗪处理病原菌体外超微结构的变化。
Mykosen Pub Date : 1987-05-01 DOI: 10.1111/j.1439-0507.1987.tb03968.x
A Virgili, A Aleotti, P Masperi, G L Vannini
{"title":"Ultrastructural changes in pathogenic fungi treated in vitro with chlorpromazine.","authors":"A Virgili, A Aleotti, P Masperi, G L Vannini","doi":"10.1111/j.1439-0507.1987.tb03968.x","DOIUrl":"https://doi.org/10.1111/j.1439-0507.1987.tb03968.x","url":null,"abstract":"Summary: The antifungal activity of chlorpromazine, an antispychotic phenothiazine, was evaluated in vitro in Candida albicans blastospores and Trichophyton mentagrophytes hyphae. The minimal inhibitory concentrations (MIC) were 40 μg/ml for the yeast and 20 μg/ml for the dermatophyte. The most striking ultrastructural changes following treatment with the MIC consisted in the deterioration of organelles membranes, disorganization of cytoplasmic structures and autolysis. It seems plausible that the fungal toxicity of chlorpromazine depends on its direct interaction with the membranes.","PeriodicalId":18826,"journal":{"name":"Mykosen","volume":"30 5","pages":"201-9"},"PeriodicalIF":0.0,"publicationDate":"1987-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb03968.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14429233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A comparative trial of bifonazole 1% cream and clotrimazole 1% cream in the treatment of candidal balanoposthitis. 1% bifonazole乳膏与1% clotrimazole乳膏治疗念珠菌性balanopthitis的比较研究。
Mykosen Pub Date : 1987-05-01 DOI: 10.1111/j.1439-0507.1987.tb03972.x
R D Maw, T Horner, J Evans
{"title":"A comparative trial of bifonazole 1% cream and clotrimazole 1% cream in the treatment of candidal balanoposthitis.","authors":"R D Maw, T Horner, J Evans","doi":"10.1111/j.1439-0507.1987.tb03972.x","DOIUrl":"https://doi.org/10.1111/j.1439-0507.1987.tb03972.x","url":null,"abstract":"Summary: One hundred patients with a diagnosis of candidal balanoposthitis were treated using either Bifonazole 1% cream or Clotrimazole 1% cream on a randomized basis. Fifty patients (Group A) received Bifonazole 1% to be applied once only per day for six days, the remaining 50 received Clotrimazole 1% (Group B) to be applied twice daily for six days. Follow‐up at day 7 after exclusion, showed that 21 of 27 patients (77.8%) in Group A and 20 of 26 patients (76.9%) in Group B had negative mycology cultures.","PeriodicalId":18826,"journal":{"name":"Mykosen","volume":"30 5","pages":"229-32"},"PeriodicalIF":0.0,"publicationDate":"1987-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb03972.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14735014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A case of disseminated Scedosporium apiospermum infection after bone marrow transplantation. 骨髓移植后播散性顶精子隐孢子虫感染1例。
Mykosen Pub Date : 1987-04-01 DOI: 10.1111/j.1439-0507.1987.tb03961.x
D Guyotat, M A Piens, R Bouvier, D Fiere
{"title":"A case of disseminated Scedosporium apiospermum infection after bone marrow transplantation.","authors":"D Guyotat, M A Piens, R Bouvier, D Fiere","doi":"10.1111/j.1439-0507.1987.tb03961.x","DOIUrl":"https://doi.org/10.1111/j.1439-0507.1987.tb03961.x","url":null,"abstract":"Summary: A case of disseminated Scedosporium apiospermum infection in a patient undergoing bone marrow transplantation for chronic myeloid leukemia is reported. Because of graft rejection, the patient received a second transplantation 35 days after the first one, at which time he had a high fever and abdominal pains. A pulmonary infiltrate developed seven days later and S. apiospermum was grown from a bronchoalveolar lavage. The patient died 25 days after the second transplant with diffuse pulmonary infiltrates, renal failure and neurologic symptoms. An autopsy revealed a disseminated S. apiospermum infection, involving the lungs, kidneys, liver, spleen, gastrointestinal tract and the brain. The pathogen was resistant to amphotericin B and 5‐fluorocytosine, but susceptible to miconazole and ketoconazole.","PeriodicalId":18826,"journal":{"name":"Mykosen","volume":"30 4","pages":"151-4"},"PeriodicalIF":0.0,"publicationDate":"1987-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb03961.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14422090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Fungal infections in birds in captivity--six case reports. 圈养鸟类真菌感染——六例报告。
Mykosen Pub Date : 1987-04-01 DOI: 10.1111/j.1439-0507.1987.tb03963.x
J Van Cutsem, J Fransen
{"title":"Fungal infections in birds in captivity--six case reports.","authors":"J Van Cutsem, J Fransen","doi":"10.1111/j.1439-0507.1987.tb03963.x","DOIUrl":"https://doi.org/10.1111/j.1439-0507.1987.tb03963.x","url":null,"abstract":"Summary: Six case reports of birds in captivity with fungal infections, associated or not with other pathogens, are presented. Hatched avocets died in the first two weeks of life from aspergillosis of the respiratory tract and infection of the mucous membranes and skin by Candida albicans. A necropsy on an adult peewit and an adult oyster‐catcher presented several infection sites by C. albicans and Staphylococcus aureus. Toxoplasma cysts were observed in necrotic skin tissue of the oyster‐catcher. After necropsy, aspergillosis was diagnosed in a mynah. Several canaries died after an invasion of almost all internal organs by Aspergillus fumigatus, associated with St. aureus in some organs. A sixth case, a red‐tailed hawk, was dyspnoeic and died with invasion of the heart, lungs, air sacs and almost all abdominal organs, by A. fumigatus.","PeriodicalId":18826,"journal":{"name":"Mykosen","volume":"30 4","pages":"166-71"},"PeriodicalIF":0.0,"publicationDate":"1987-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb03963.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14422091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Experimental chronic lingual candidosis induced in streptozotocin diabetic rats. 链脲佐菌素诱导糖尿病大鼠慢性舌念珠菌病的实验研究。
Mykosen Pub Date : 1987-04-01 DOI: 10.1111/j.1439-0507.1987.tb03965.x
N Dourov, J Coremans-Pelseneer
{"title":"Experimental chronic lingual candidosis induced in streptozotocin diabetic rats.","authors":"N Dourov, J Coremans-Pelseneer","doi":"10.1111/j.1439-0507.1987.tb03965.x","DOIUrl":"https://doi.org/10.1111/j.1439-0507.1987.tb03965.x","url":null,"abstract":"Summary: A single application of C. albicans on the tongue of streptozotocin treated rats makes it possible to study long‐term mycotic lesions of lingual mucosa, such as loss of filiform papillae and parakeratosis. The giant conical papillae region is destroyed and irregular depression of the central portion of the dorsal mucosa appears. The epithelium is irregularly thickened and the derm is diffusely infiltrated by lymphocytes. No dysplastic or neoplastic lesions of the mucosa were observed, even after ten months of infection.","PeriodicalId":18826,"journal":{"name":"Mykosen","volume":"30 4","pages":"175-83"},"PeriodicalIF":0.0,"publicationDate":"1987-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb03965.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14422092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Fungistatic and fungicidal effects of amphotericin B, ketoconazole and fluconazole (UK 49,858) against histoplasma capsulatum in vitro and in vivo. 两性霉素B、酮康唑和氟康唑(UK 49,858)对荚膜组织浆体的体内体外抑菌作用
Mykosen Pub Date : 1987-04-01 DOI: 10.1111/j.1439-0507.1987.tb03967.x
A Polak, D M Dixon
{"title":"Fungistatic and fungicidal effects of amphotericin B, ketoconazole and fluconazole (UK 49,858) against histoplasma capsulatum in vitro and in vivo.","authors":"A Polak, D M Dixon","doi":"10.1111/j.1439-0507.1987.tb03967.x","DOIUrl":"https://doi.org/10.1111/j.1439-0507.1987.tb03967.x","url":null,"abstract":"Summary: Amphotericin B (Amph B), ketoconazole (KTZ) and fluconazole (FLZ) were compared for activity against yeast phase H. capsulatum in vitro and in Swiss albino mice. A quantitative spleen culture technique for yeast phase colony forming units (CFU) was used to evaluate the antifungal effects of these 3 drugs in vivo. In contrast to the in vitro indications, all 3 drugs showed fungicidal activity as demonstrated by the exponential decreases in CFU from spleens of infected mice. When relating the fungicidal activity obtained by this technique to the ED50 or ED100 values, KTZ and FTZ appeared to be the most active drugs. Fluconazole compared favorably to KTZ. At twice the ED100 Amph B had no significant effect upon viable yeasts recovered until after day 3 or infection (p ≤ 0.01). Thereafter, the drug was fungicidal. Based upon these studies, FLZ would appear to hold promise in the clinical management of histoplasmosis.","PeriodicalId":18826,"journal":{"name":"Mykosen","volume":"30 4","pages":"186-94"},"PeriodicalIF":0.0,"publicationDate":"1987-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb03967.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14167926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Aspergillus terreus as a possible cause of mycetoma on the foot of a dog. 土曲霉可能引起狗脚上的足菌肿。
Mykosen Pub Date : 1987-04-01 DOI: 10.1111/j.1439-0507.1987.tb03964.x
M Pal, J D Verma
{"title":"Aspergillus terreus as a possible cause of mycetoma on the foot of a dog.","authors":"M Pal, J D Verma","doi":"10.1111/j.1439-0507.1987.tb03964.x","DOIUrl":"https://doi.org/10.1111/j.1439-0507.1987.tb03964.x","url":null,"abstract":"Summary: Aspergillus terreus, a soil‐borne fungus, has been found incriminated as an opportunistic etiologic agent of canine mycetoma. The dog had a chronic swelling on the second digit of the right hind‐leg. The pathogen was isolated from the amputated digit on Sabouraud's medium at 37°C, and demonstrated in the clinical specimen by the potassium hydroxide technique. The isolate was virulent to white Swiss mice and sensitive to nystatin.","PeriodicalId":18826,"journal":{"name":"Mykosen","volume":"30 4","pages":"172-4"},"PeriodicalIF":0.0,"publicationDate":"1987-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb03964.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14708965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Mycological and epidemiological studies on trichophyton terrestre in cats. 猫毛癣菌的真菌学和流行病学研究。
Mykosen Pub Date : 1987-04-01 DOI: 10.1111/j.1439-0507.1987.tb03962.x
R Aho, A A Padhye, L Ajello
{"title":"Mycological and epidemiological studies on trichophyton terrestre in cats.","authors":"R Aho, A A Padhye, L Ajello","doi":"10.1111/j.1439-0507.1987.tb03962.x","DOIUrl":"https://doi.org/10.1111/j.1439-0507.1987.tb03962.x","url":null,"abstract":"Summary: Trichophyton terrestre was isolated from twenty of 276 cats examined (7.2%) in seven catteries. The catteries that gave positive isolations of T. terrestre were: a) three catteries that bred mainly Persian cats, but also had one or more outdoor‐indoor European shorthair cats, b) one cattery that bred European shorthair cats and colorpoint Persians, c) one cattery that bred only European shorthairs, d) one that bred only Persian cats, and e) one cattery that bred four different breeds including European shorthairs as well as Persian cats. The isolation of T. terrestre was significantly more often achieved from European shorthairs than from Persian cats, and from the group of European shorthairs and Persians kept together than from an other breeds. The hairbrush technique was found to be the most reliable method of sampling especially when the cats were asymptomatic. None of the 276 cats examined yielded Microsporum canis. Diluted Sabouraud dextrose agar containing chloramphenicol and cycloheximide was the medium of choice for the isolation of T. terrestre. Of the 21 isolates, three produced creamy white, downy colonies, while 18 developed red‐pigmented, granular colonies. Microconidia were numerous. They were 1‐celled, cylindric to clavate and were borne singly. Four isolates also produced smoothwalled, cylindric to cigar‐shaped, 2–4–celled macroconidia. Spiral hyphae were observed. In addition, three isolated produced Arthroderma‐type peridial hyphae but none developed pseudo‐ or fertile gymnothecia.","PeriodicalId":18826,"journal":{"name":"Mykosen","volume":"30 4","pages":"157-65"},"PeriodicalIF":0.0,"publicationDate":"1987-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb03962.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14708964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
[Molds in the household]. [家里的霉菌]。
Mykosen Pub Date : 1987-03-01
J Reiss
{"title":"[Molds in the household].","authors":"J Reiss","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18826,"journal":{"name":"Mykosen","volume":"30 3","pages":"127-33"},"PeriodicalIF":0.0,"publicationDate":"1987-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14708960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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