{"title":"链脲佐菌素诱导糖尿病大鼠慢性舌念珠菌病的实验研究。","authors":"N Dourov, J Coremans-Pelseneer","doi":"10.1111/j.1439-0507.1987.tb03965.x","DOIUrl":null,"url":null,"abstract":"Summary: A single application of C. albicans on the tongue of streptozotocin treated rats makes it possible to study long‐term mycotic lesions of lingual mucosa, such as loss of filiform papillae and parakeratosis. The giant conical papillae region is destroyed and irregular depression of the central portion of the dorsal mucosa appears. The epithelium is irregularly thickened and the derm is diffusely infiltrated by lymphocytes. No dysplastic or neoplastic lesions of the mucosa were observed, even after ten months of infection.","PeriodicalId":18826,"journal":{"name":"Mykosen","volume":"30 4","pages":"175-83"},"PeriodicalIF":0.0000,"publicationDate":"1987-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb03965.x","citationCount":"12","resultStr":"{\"title\":\"Experimental chronic lingual candidosis induced in streptozotocin diabetic rats.\",\"authors\":\"N Dourov, J Coremans-Pelseneer\",\"doi\":\"10.1111/j.1439-0507.1987.tb03965.x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Summary: A single application of C. albicans on the tongue of streptozotocin treated rats makes it possible to study long‐term mycotic lesions of lingual mucosa, such as loss of filiform papillae and parakeratosis. The giant conical papillae region is destroyed and irregular depression of the central portion of the dorsal mucosa appears. The epithelium is irregularly thickened and the derm is diffusely infiltrated by lymphocytes. No dysplastic or neoplastic lesions of the mucosa were observed, even after ten months of infection.\",\"PeriodicalId\":18826,\"journal\":{\"name\":\"Mykosen\",\"volume\":\"30 4\",\"pages\":\"175-83\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1987-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb03965.x\",\"citationCount\":\"12\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Mykosen\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1111/j.1439-0507.1987.tb03965.x\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mykosen","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/j.1439-0507.1987.tb03965.x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Experimental chronic lingual candidosis induced in streptozotocin diabetic rats.
Summary: A single application of C. albicans on the tongue of streptozotocin treated rats makes it possible to study long‐term mycotic lesions of lingual mucosa, such as loss of filiform papillae and parakeratosis. The giant conical papillae region is destroyed and irregular depression of the central portion of the dorsal mucosa appears. The epithelium is irregularly thickened and the derm is diffusely infiltrated by lymphocytes. No dysplastic or neoplastic lesions of the mucosa were observed, even after ten months of infection.
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