Mykosen Pub Date : 1987-07-01

J Faergemann

引用次数: 0

[Multicenter study of the standardization of sensitivity testing of fungi to 5-fluorocytosine and amphotericin B]. 真菌对5-氟胞嘧啶和两性霉素B敏感性检测标准化的多中心研究

Mykosen Pub Date : 1987-07-01

A Polak

引用次数: 0

Candida albicans and Candida tropicalis antigens studied by SDS polyacrylamide gel electrophoresis and Western blot. 采用SDS聚丙烯酰胺凝胶电泳和Western blot技术研究白色念珠菌和热带念珠菌抗原。

Mykosen Pub Date : 1987-06-01 DOI: 10.1111/j.1439-0507.1987.tb03979.x

S M Bruneau, R M Guinet

{"title":"Candida albicans and Candida tropicalis antigens studied by SDS polyacrylamide gel electrophoresis and Western blot.","authors":"S M Bruneau, R M Guinet","doi":"10.1111/j.1439-0507.1987.tb03979.x","DOIUrl":"https://doi.org/10.1111/j.1439-0507.1987.tb03979.x","url":null,"abstract":"Summary: The SDS extracts of blastospores from 14 Candida albicans strains and from 8 Candida tropicalis strains were studied by SDS polyacrylamide gel electrophoresis. The Coomassie blue staining revealed more than 40 polypeptides; 4 from Candida albicans and 5 from Candida tropicalis were major polypeptides with molecular weights (M.W.) of 34 to 54 kDa. The extracts obtained by the mechanical disruption of yeasts cells and those obtained by the SDS whole‐cell treatment showed several differences especially with polypeptides ranging from 67 to 94 kDa and from 20 to 30 kDa – the major polypeptides were extracted by the both procedures. All the gels run with the SDS extracts from the strains of same species strains gave identical patterns but several polypeptides including the major ones showed different M.W. when extracted from Candida albicans or Candida tropicalis. However the antigens of these two species previously studied by quantitative Immunoelectrophoresis techniques (QIE) had shown more than 85% of cross‐reactions. (Gabriel‐Bruneau and Guinet 1984 [5]).","PeriodicalId":18826,"journal":{"name":"Mykosen","volume":"30 6","pages":"271-80"},"PeriodicalIF":0.0,"publicationDate":"1987-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb03979.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14435153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Macroconidial formation in Trichophyton soudanense Joyeux 1912. 苏丹毛癣菌的大孢子形成Joyeux 1912。

Mykosen Pub Date : 1987-06-01 DOI: 10.1111/j.1439-0507.1987.tb03976.x

L Ajello, A A Padhye

引用次数: 6

Clinical and immunological follow-up of trichophytic kerion celsi. 毛癣性角质细胞的临床及免疫学随访。

Mykosen Pub Date : 1987-06-01 DOI: 10.1111/j.1439-0507.1987.tb03974.x

M Papini, S Simonetti

引用次数: 4

Inhibitory effect of antifungal agents on germ tube formation in Candida albicans. 抗真菌药物对白色念珠菌芽管形成的抑制作用。

Mykosen Pub Date : 1987-06-01 DOI: 10.1111/j.1439-0507.1987.tb03980.x

M Schaude, H Ackerbauer, H Mieth

{"title":"Inhibitory effect of antifungal agents on germ tube formation in Candida albicans.","authors":"M Schaude, H Ackerbauer, H Mieth","doi":"10.1111/j.1439-0507.1987.tb03980.x","DOIUrl":"https://doi.org/10.1111/j.1439-0507.1987.tb03980.x","url":null,"abstract":"Summary: The allylamine derivatives naftifine and terbinafine were compared in vitro with 15 standard antifungals in terms of their inhibitory effects on the yeast‐mycelial (Y‐M) transformation in tests with 19 Candida albicans isolates. Y‐M transformation minimal inhibitory concentration (MICs) were determined in a microtiter‐broth‐dilution test using a chemically defined medium with N‐acetyglucosamine as inducer of hyphal growth. Clotrimazole was the most potent inhibitor with a geometric mean MIC (G‐MIC) value of 0.00038 μg ml‐1 followed by ketoconazole (G‐MIC,0.012 μg ml‐1) and itraconazole (G‐MIC,0.027 μg ml‐1) in that order. G‐MIC values ranging from 0.027–0.037 μg ml‐1 have been determined for itraconazole, econazole, amorolfine (RO 14–4767/002), miconazole and 5‐fluorocytosine. Among the orally active azole derivatives fluconazole was the least active (G‐MIC,0.14 μg ml‐1). Noteworthy activity included that of the allylamine terbinafine which was similar to that of bifonazole (G‐MIC 0.23–0.26 μg ml‐1). There was a statistically significant higher susceptibility of the test strains with terbinafine than with amphotericin B. Naftifine and amphotericin B were comparable active in terms of G‐MIC values (0.52–0.7 μg ml‐1). Significantly higher drug concentrations (> 1 μg ml‐1) were necessary to inhibit filamentation of C. albicans with ciclopiroxolamine, nystatin, griseofulvin and tolciclate. Tolnaftate was the least active drug tested with a G‐MIC of 74.7 μg ml‐1.","PeriodicalId":18826,"journal":{"name":"Mykosen","volume":"30 6","pages":"281-7"},"PeriodicalIF":0.0,"publicationDate":"1987-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1439-0507.1987.tb03980.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14435154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 47

[A method for the quantitative determination of yeasts]. [酵母的定量测定方法]。

Mykosen Pub Date : 1987-06-01

H Listemann, W Meigel

引用次数: 0

Experience with itraconazole in deep mycoses in northern Italy. 伊曲康唑治疗意大利北部深部真菌病的经验。

Mykosen Pub Date : 1987-05-01 DOI: 10.1111/j.1439-0507.1987.tb03973.x

M A Viviani, A M Tortorano, R Woenstenborghs, G Cauwenbergh

引用次数: 47

[Localized intracavitary mucormycosis of the maxillary sinus in a patient without discernible predisposition]. [上颌窦腔内毛霉菌病患者无明显易感性]。

Mykosen Pub Date : 1987-05-01

R Develey, F Bartlome-Gallandre, M Gasser, H J Scholer