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S133 Disparities in Clinical Outcomes Between Younger and Older UC Patients With Respect to Insurance Status: An Analysis of the National Inpatient Sample 2016-2020 S133 与保险状况有关的年轻和老年 UC 患者临床结果的差异：2016-2020年全国住院患者样本分析
The American Journal of Gastroenterology Pub Date : 2023-12-01 DOI: 10.14309/01.ajg.0000996276.43941.bd
C. Chhoun, Fanchen Zhou, Jianle Gao, Marisa Pope, David J. Truscello, N. Dasu, Yaser Khalid
{"title":"S133 Disparities in Clinical Outcomes Between Younger and Older UC Patients With Respect to Insurance Status: An Analysis of the National Inpatient Sample 2016-2020","authors":"C. Chhoun, Fanchen Zhou, Jianle Gao, Marisa Pope, David J. Truscello, N. Dasu, Yaser Khalid","doi":"10.14309/01.ajg.0000996276.43941.bd","DOIUrl":"https://doi.org/10.14309/01.ajg.0000996276.43941.bd","url":null,"abstract":"Background: Parenteral glucocorticoids are a well-established treatment for acute severe ulcerative colitis(ASUC) fl aresin hospitalizedpatients. Mostreportsymptomaticimprovementwithin3-5days of startingtreatment. However,forthose withno improvementafter 5 days,considerationof second-line agents, such as in fl iximab or cyclosporine, is warranted. We report a case of ASUC and con-comitantCMV infectionrefractorytosystemicsteroidsand ganciclovir,requiringaddition ofa TNF-alpha inhibitor. Methods: A 40-year-old female with a history of iron-de fi ciency anemia presented with a 1-month history of abdominal pain and hematochezia. Prior fl exible sigmoidoscopy showed moderate in-fl ammation from 25cm to the anal verge, and biopsies were consistent with UC. She was discharged with a 20mg prednisone taper and PO mesalamine. Despite therapy, patient had worsening hema-tochezia, frequent nocturnal stooling, arthralgias, and weight loss, prompting return to the hospital. On admission, fecal calprotectin was elevated, 248 mcg/g. She was started on IV Solumedrol, 20mg every 8 hours. Results: After 3 days of treatment, her pain and hematochezia were persistent. GI PCR and C. di ff testing were negative, and she required blood transfusion for symptomatic anemia. Repeat colonoscopy to the transverse colon showed Mayo 3 left-sided colitis, and biopsies were consistent with UC with moderate in fl ammatory activity. Biopsied tissue was PCR-positive for CMV infection. Patient was started on IV ganciclovir, 5mg/kg twice daily. Following 3 days of treatment for CMV, symptoms had not improved. After discussing risks/bene fi ts between consulting services, in fl iximab 10mg/kg was started with signi fi cant symptom improvement the following day, with stool frequency decreased to 3-4 daily from 10 1 . She was discharged on a 40mg","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"297 ","pages":"S35 - S36"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139024931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
S45 Highlighting Disparities and Outcomes in Pregnant Patients With Inflammatory Bowel Disease (IBD): Does Race Matter? S45 强调妊娠期炎症性肠病 (IBD) 患者的差异和结果：种族是否重要？
The American Journal of Gastroenterology Pub Date : 2023-12-01 DOI: 10.14309/01.ajg.0000995920.77325.15
David J. Truscello, J. John, B. Blair, Yaser Khalid, N. Dasu
{"title":"S45 Highlighting Disparities and Outcomes in Pregnant Patients With Inflammatory Bowel Disease (IBD): Does Race Matter?","authors":"David J. Truscello, J. John, B. Blair, Yaser Khalid, N. Dasu","doi":"10.14309/01.ajg.0000995920.77325.15","DOIUrl":"https://doi.org/10.14309/01.ajg.0000995920.77325.15","url":null,"abstract":", immunohistochemical staining for IgG4 was performed on the patient ’ s colon biopsies, which revealed a high percentage of the IgG cells in the lamina propria with . 50% positivity for IgG4. This con fi rmed the patient ’ s IgG4 mediated colitis, and he has now started rituximab therapy. Conclusions: We demonstrate a case of IgG4-RD misclassi fi ed as CD and GPA and emphasize the importance of consideration of this rare disorder in appropriate patients. Clinical follow-up and response to rituximab will be described at the time of this case presentation.","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"239 ","pages":"S12 - S13"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139024993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
S41 Case Report: Immunoglobulin G4-Related Disease Mistaken for Crohn’s Disease S41 病例报告：免疫球蛋白 G4 相关疾病被误认为克罗恩病
The American Journal of Gastroenterology Pub Date : 2023-12-01 DOI: 10.14309/01.ajg.0000995904.06419.f0
E. Picker, Reem Jan, Christopher R. Weber, L. Yassan, John Hart, D. T. Rubin
{"title":"S41 Case Report: Immunoglobulin G4-Related Disease Mistaken for Crohn’s Disease","authors":"E. Picker, Reem Jan, Christopher R. Weber, L. Yassan, John Hart, D. T. Rubin","doi":"10.14309/01.ajg.0000995904.06419.f0","DOIUrl":"https://doi.org/10.14309/01.ajg.0000995904.06419.f0","url":null,"abstract":"and adalimumab (0.003), and ustekinumab/vedolizumab (0.002). We also looked at outcomes of the patients who had HF as an adverse event due to biologics, including hospitalizations and it showed it was highest with adalimumab,followed by In fl iximab and vedolizumab. The other outcome we looked at was mortality for patients who had HF with biologics, it was highest in patients who had used adalimumab, followed by In fl iximab and ustekinumab. Conclusions: Our study adds further to the literature regarding biologics adverse events, speci fi cally heart failure. Tofacitinib had the highest ratio of heart failure among all adverse e ff ects, followed by the already-established In fl iximab. All other newer biologics had a relatively lower ratio. Despite tofacitinibhavingthehighestratioforheartfailure,wecannotattributesigni fi cancetothisduetothis drug having only one reported case compared to other drugs. Furthermore, we can conclude that newer biologics have a relatively very small ratio for the risk of heart failure compared to In fl iximab. Further data is needed for the newer biologics.","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"65 10","pages":"S11 - S12"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139026188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
S79 Effects of NSTEMI on Patients With Ulcerative Colitis: Insights From the National Inpatient Sample S79 NSTEMI 对溃疡性结肠炎患者的影响：全国住院病人抽样调查的启示
The American Journal of Gastroenterology Pub Date : 2023-12-01 DOI: 10.14309/01.ajg.0000996060.50620.d7
T. Elias, R. Beshai, Mark Tawfik, Charles Yang, Joshua Soliman, Lucy Joo, Howard M. Weinberg, Peter Bulik
{"title":"S79 Effects of NSTEMI on Patients With Ulcerative Colitis: Insights From the National Inpatient Sample","authors":"T. Elias, R. Beshai, Mark Tawfik, Charles Yang, Joshua Soliman, Lucy Joo, Howard M. Weinberg, Peter Bulik","doi":"10.14309/01.ajg.0000996060.50620.d7","DOIUrl":"https://doi.org/10.14309/01.ajg.0000996060.50620.d7","url":null,"abstract":"Background: There is a paucity of data looking speci fi cally on the e ff ects of NSTEMI on patients with ulcerative colitis (UC). We sought to analyze this relationship further by examining the national inpatient sample database to describe in-hospital trends and","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"168 3","pages":"S22 - S22"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139013171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
S10 Outcomes of Early Versus Delayed Advanced Therapy Among Patients With Moderate Ulcerative Colitis in the United States: TARGET-IBD S10 美国中度溃疡性结肠炎患者早期与延迟晚期治疗的结果：TARGET-IBD
The American Journal of Gastroenterology Pub Date : 2023-12-01 DOI: 10.14309/01.ajg.0000995776.43269.ce
D. T. Rubin, E. Barnes, Shweta Shah, Harris A. Ahmad, D. Gazis, H. Morris, J. Crawford, Megan Lutz, Marla C. Dubinsky, Miguel Regueiro
{"title":"S10 Outcomes of Early Versus Delayed Advanced Therapy Among Patients With Moderate Ulcerative Colitis in the United States: TARGET-IBD","authors":"D. T. Rubin, E. Barnes, Shweta Shah, Harris A. Ahmad, D. Gazis, H. Morris, J. Crawford, Megan Lutz, Marla C. Dubinsky, Miguel Regueiro","doi":"10.14309/01.ajg.0000995776.43269.ce","DOIUrl":"https://doi.org/10.14309/01.ajg.0000995776.43269.ce","url":null,"abstract":"","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"209 1","pages":"S3 - S4"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139013575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
S9 Real-World Outcomes of Dual Advanced Therapy in Inflammatory Bowel Disease S9 炎症性肠病双重先进疗法的实际效果
The American Journal of Gastroenterology Pub Date : 2023-12-01 DOI: 10.14309/01.ajg.0000995772.48171.4c
A. Kellar, M. Dolinger, E. Spencer, Marla C. Dubinsky
{"title":"S9 Real-World Outcomes of Dual Advanced Therapy in Inflammatory Bowel Disease","authors":"A. Kellar, M. Dolinger, E. Spencer, Marla C. Dubinsky","doi":"10.14309/01.ajg.0000995772.48171.4c","DOIUrl":"https://doi.org/10.14309/01.ajg.0000995772.48171.4c","url":null,"abstract":"","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"980 ","pages":"S3 - S3"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139014314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
S93 Autoimmune Hemolytic Anemia Occurring After Laparoscopic Total Colectomy With Ileorectal Anastomosis in a Patient With Ulcerative Colitis: A Case report S93 一名溃疡性结肠炎患者腹腔镜全结肠切除术与回直肠吻合术后发生的自身免疫性溶血性贫血：病例报告
The American Journal of Gastroenterology Pub Date : 2023-12-01 DOI: 10.14309/01.ajg.0000996116.52805.3b
Taehyung Kim, Soo Jeong Kim
{"title":"S93 Autoimmune Hemolytic Anemia Occurring After Laparoscopic Total Colectomy With Ileorectal Anastomosis in a Patient With Ulcerative Colitis: A Case report","authors":"Taehyung Kim, Soo Jeong Kim","doi":"10.14309/01.ajg.0000996116.52805.3b","DOIUrl":"https://doi.org/10.14309/01.ajg.0000996116.52805.3b","url":null,"abstract":".Thiscaseseriespresented4patientswithCDwhoreceivedsirolimustherapyforaprimaryindicationofrefractoryCD.Allpatientshadfailedtreatmentwithatleast6otherIBD-therapies. Our results reveal 1 of 4 patients reporting symptomatic improvement and whilst treatment escalation was not required, imaging measures of in fl ammation remained equivocal. Furthermore, all 4 patients required sirolimus discontinuation due to adverse e ff ects. With minimal data currently available for use of sirolimus therapy in adults with refractory IBD, our fi ndings suggest that its role may be limited by treatment-derived adverse e ff ects. Further large-scale studies are needed to investigate the e ffi ciency of sirolimus therapy in refractory IBD, with particular attention to treatment-limiting adverse e ff ects.","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"137 ","pages":"S25 - S26"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139014506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
S136 Use of Teduglutide in a Patient With Ulcerative Colitis and Short Bowel Syndrome: Case Report S136 在溃疡性结肠炎和短肠综合征患者中使用泰度鲁肽：病例报告
The American Journal of Gastroenterology Pub Date : 2023-12-01 DOI: 10.14309/01.ajg.0000996288.46095.e0
Clarissa Maria Almeida, Paulo Roberto Ramaciotti Filho, Sandra di Felice Boratto, Aline Zara, Amanda Brosco, Mathew Kazmirik
{"title":"S136 Use of Teduglutide in a Patient With Ulcerative Colitis and Short Bowel Syndrome: Case Report","authors":"Clarissa Maria Almeida, Paulo Roberto Ramaciotti Filho, Sandra di Felice Boratto, Aline Zara, Amanda Brosco, Mathew Kazmirik","doi":"10.14309/01.ajg.0000996288.46095.e0","DOIUrl":"https://doi.org/10.14309/01.ajg.0000996288.46095.e0","url":null,"abstract":"The","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"50 ","pages":"S36 - S36"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139018301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
S108 Addressing Issues Important to Young Adults With IBD: The Impact of a Multistakeholder Roundtable on Sexual Health, Reproductive Health, and Family Planning Roundtable S108 解决对患有 IBD 的年轻人很重要的问题：多方利益相关者圆桌会议对性健康、生殖健康和计划生育的影响 圆桌会议
The American Journal of Gastroenterology Pub Date : 2023-12-01 DOI: 10.14309/01.ajg.0000996176.61009.c3
Linda Yoo, Mara Shapiro, Laurel Dorr, Divya Mehrish, Hilary K. Michel, Sneha P. Dave, Sandra Kim
{"title":"S108 Addressing Issues Important to Young Adults With IBD: The Impact of a Multistakeholder Roundtable on Sexual Health, Reproductive Health, and Family Planning Roundtable","authors":"Linda Yoo, Mara Shapiro, Laurel Dorr, Divya Mehrish, Hilary K. Michel, Sneha P. Dave, Sandra Kim","doi":"10.14309/01.ajg.0000996176.61009.c3","DOIUrl":"https://doi.org/10.14309/01.ajg.0000996176.61009.c3","url":null,"abstract":"","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"14 12","pages":"S29 - S29"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139019848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
S13 Methodological Considerations of Network Meta-Analyses: Improving Evaluation of Comparative Effectiveness and Safety of Advanced Therapies Treating Moderate to Severe Ulcerative Colitis S13 网络元分析的方法学考虑：改进对治疗中度至重度溃疡性结肠炎的先进疗法的有效性和安全性的比较评价
The American Journal of Gastroenterology Pub Date : 2023-12-01 DOI: 10.14309/01.ajg.0000995788.76745.fe
Ashley Bonner, Kiran Dave, Shweta Shah, Parash Bhandari, Kate Lebedeva, Seyavash Najle Rahim, Michael West
{"title":"S13 Methodological Considerations of Network Meta-Analyses: Improving Evaluation of Comparative Effectiveness and Safety of Advanced Therapies Treating Moderate to Severe Ulcerative Colitis","authors":"Ashley Bonner, Kiran Dave, Shweta Shah, Parash Bhandari, Kate Lebedeva, Seyavash Najle Rahim, Michael West","doi":"10.14309/01.ajg.0000995788.76745.fe","DOIUrl":"https://doi.org/10.14309/01.ajg.0000995788.76745.fe","url":null,"abstract":"","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"184 ","pages":"S4 - S5"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139020662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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