The American Journal of Gastroenterology最新文献

{"title":"S37 Incorporation of a Screening Program for Mental Health in Inflammatory Bowel Disease Identifies Many Patients With Undiagnosed or Ineffectively Treated Anxiety and Depression","authors":"N. Choi, Alexandra McDermott, E. Picker, Adar Zinger, Alyse Bedell, D. T. Rubin","doi":"10.14309/01.ajg.0000995884.64059.94","DOIUrl":"https://doi.org/10.14309/01.ajg.0000995884.64059.94","url":null,"abstract":"his weight had increased from 127 to 149 pounds, he was experiencing a clinical remission and down to 15mg prednisone daily. At 3 month follow up he was in steroid free clinical remission. Conclusions: UPA is e ff ective in achieving rapid clinical response assessed by improvement in the bowel wall thickness and vascularity on IUS in a patient with ASUC. This case report is the fi rst to show treatment response after induction with UPA in a patient with ASUC with IUS as an objective tool, o ff ering an additional non-invasive, cost-e ff ective method for monitoring disease activity as well as an alternative salvage treatment in those with ASUC who fail anti-TNF medications. Further prospective studies are needed to assess e ff ectiveness of UPA in ASUC as well as IUS monitoring in this population.","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"900 ","pages":"S10 - S11"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139022631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"S12 Rate of Ustekinumab Dose Escalation in Patients With Crohn’s Disease Who Had a History of Anti-TNF Dose Escalation","authors":"Kelly Sun, Scott Manski, Albert Crawford, Raina Shivashankar","doi":"10.14309/01.ajg.0000995784.94751.8a","DOIUrl":"https://doi.org/10.14309/01.ajg.0000995784.94751.8a","url":null,"abstract":"","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"1100 ","pages":"S4 - S4"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139014203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"S61 High Red Meat Consumption is Associated With Greater Risk of Ulcerative Colitis Flare","authors":"Adar Zinger, E. Barnes, L. Weisbein, Michael Kappelman, Dejan Micic","doi":"10.14309/01.ajg.0000995988.33419.a7","DOIUrl":"https://doi.org/10.14309/01.ajg.0000995988.33419.a7","url":null,"abstract":"","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"266 ","pages":"S17 - S17"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139016287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"S143 Prevalence, Epidemiology, and Association of Barrett’s Esophagus Among Patients With Inflammatory Bowel Disease: A National Estimate","authors":"D. Budh, Harshavardhan Sanekommu, H. V. Chawla, J. Ravilla, Sana Zafar, Iryna Kozak, Navyatha Annareddy, Francis Vino Dominic Savio, Roghayeh Marandi, Ruslan Ilyassov, Prasanthi Vanga, Ritvika Panghal, Nilay Bhatt, Urvish K Patel, Pranav D. Patel","doi":"10.14309/01.ajg.0000996316.02243.fd","DOIUrl":"https://doi.org/10.14309/01.ajg.0000996316.02243.fd","url":null,"abstract":"treatment of UC, as it indicates complete healing of the intestinal mucosa and is associated with better long-term results. Di ff erences were observed in the types of remission achieved with di ff erent therapeutic options, in fl iximab and 5-ASA were the treatments most frequently associated with deep remission, while certolizumab and adalimumab were more common in biochemical and histological remission. It is important to note sample size which was relatively small. In conclusion, this study provides strong evidence that histological remission is achievable in patients with ulcerative colitis. Theseresults supporttheimportanceof histologicalremissionas atherapeuticgoal, asit isassociated with signi fi cant clinical improvement and more favorable long-term outcomes.","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"132 ","pages":"S38 - S38"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139016793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"S47 Treatment Persistence Among Anti-TNF-Experienced Patients With Ulcerative Colitis Switching to Ustekinumab or Cycling to Another Anti-TNF Agent","authors":"M. Zhdanava, Sabree C Burbage, Porpong Boonmak, Sumesh Kachroo, Patrick Lefebvre, Aditi Shah, B. Godwin, D. Pilon","doi":"10.14309/01.ajg.0000995932.72952.a8","DOIUrl":"https://doi.org/10.14309/01.ajg.0000995932.72952.a8","url":null,"abstract":"Ustekinumab","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"88 ","pages":"S13 - S13"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139017621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"S144 Histological Remission: The Ultimate Goal in Ulcerative Colitis","authors":"Raul Sosa-Martinez, Daniela A. Garcia-Alonso, Jesus G. Lopez-Gomez, T. Cortés-Espinosa","doi":"10.14309/01.ajg.0000996320.73214.12","DOIUrl":"https://doi.org/10.14309/01.ajg.0000996320.73214.12","url":null,"abstract":"treatment of UC, as it indicates complete healing of the intestinal mucosa and is associated with better long-term results. Di ff erences were observed in the types of remission achieved with di ff erent therapeutic options, in fl iximab and 5-ASA were the treatments most frequently associated with deep remission, while certolizumab and adalimumab were more common in biochemical and histological remission. It is important to note sample size which was relatively small. In conclusion, this study provides strong evidence that histological remission is achievable in patients with ulcerative colitis. Theseresults supporttheimportanceof histologicalremissionas atherapeuticgoal, asit isassociated with signi fi cant clinical improvement and more favorable long-term outcomes.","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"372 4","pages":"S38 - S38"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139022302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"S66 High Rates of Patient-Reported Outcome Measurements in Patients With Inflammatory Bowel Disease With Electronic Medical Record Implementation","authors":"Ciang Gu, Audrey Bennett, Justin Bachmann, David A. Schwartz, D. Beaulieu, Elizabeth A. Scoville, Robin L. Dalal, B. Pabla, James C. Slaughter, Sara Horst","doi":"10.14309/01.ajg.0000996008.39621.ca","DOIUrl":"https://doi.org/10.14309/01.ajg.0000996008.39621.ca","url":null,"abstract":"were","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"528 15","pages":"S18 - S18"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139023570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"S122 Evaluation of Fatigue and Nutritional Aspects in Patients With Crohn’s Disease at a Reference Center for IBD in the City of Salvador-BA","authors":"F. Fortes, Genalva Couto, Tayane Morais, G. Santana, Bruna Cruz, Gabriela Sousa, N. Almeida, Andrea Pimentel, Jaciane Fontes, V. Surlo, Raquel Rocha","doi":"10.14309/01.ajg.0000996232.17976.5f","DOIUrl":"https://doi.org/10.14309/01.ajg.0000996232.17976.5f","url":null,"abstract":"between","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"81 1","pages":"S33 - S33"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139025969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"S105 From Surgery to Symptomatology: Race’s Role in Crohn’s Disease Emergence Post-Bariatric Surgery","authors":"Raj Mohan Ram Mohan, Melvin Joy, Sai Greeshma Magam, Sai Reshma Magam, Dilman Natt, Jiten Desai, R. Jiyani, P. Mustacchia","doi":"10.14309/01.ajg.0000996164.57811.f8","DOIUrl":"https://doi.org/10.14309/01.ajg.0000996164.57811.f8","url":null,"abstract":"Background: Pediatric in fl ammatory bowel disease (IBD), de fi ned as diagnosis before the age of 19, has garnered increasing attention due to its potential implications for disease outcomes. Evidence suggests that the age of disease manifestation might in fl uence disease progression. There are very few reports of pediatric-onset IBD in Hispanics. This study aims to characterize pediatric onset of Crohn ’ s disease (CD) in a cohort of Hispanics and compare it to adult-onset CD subjects. Methods: The UPR Registry of IBD is an ongoing database actively recruiting participants since 1995. A cohort of 322 patients with con fi rmed CD recruited between 2002 and 2022 was analyzed. Subjects were categorized into pediatric ( # 18 years) and adult diagnosis ( . 19 years) cohorts. Univariate analysis was employed for population description. Categorical variables were compared via Chi2 test, while continuous variables were compared using Wilcoxon rank-sum test. Statistical signi fi cance was set at p , 0.05. The study is approved by the MSC-IRB. Results: 322 CD patients, 126 with pediatric diagnosis and 196 with adult diagnosis were included. Gender distribution, phenotype, location, hospitalizations, and surgery exhibited no signi fi cant differences (p 5 0.164,p 5 0.365, p 5 0.780, p 5 0.490, p 5 0.741, respectively). Family historyof IBD showed a trend towards signi fi cance (p 5 0.074). Pediatric patients experienced a shorter delay in diagnosis (1.2 years) compared to adults (3.7 years). The presence of extraintestinal manifestations (EIMs) showed a signi fi cant association with age at diagnosis (p 5 0.012), with pediatric subjects exhibiting a higher prevalence of EIMs (22.2%) compared to adults (11.7%). Perianal disease was signi fi cantly higher (p 5 0.039), in pediatric subjects (38.8%) than in adults (26.5%). Conclusions: This study of a Hispanic cohort of patients with IBD reveals some signi fi cant associations in disease characteristics linked to a diagnosis of CD in childhood. The higher prevalence of EIMs and perianal disease, and a shorter diagnostic delay in the pediatric group represent important di ff erences from adults. More studiesare needed to explore therole of childhoodonset in thisdisease and to guide management of this vulnerable population.","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"118 3","pages":"S28 - S29"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138988220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"S72 IBD-Associated Arthritis is Associated With Concomitant Autoimmune and Inflammatory Disorders","authors":"Madeline Alizadeh, Uni Wong, Bernadette C. Siaton, Seema A. Patil, Lauren George, J. Raufman, William H. Scott, Erik C. von Rosenvinge, Jacques Ravel, Raymond Cross","doi":"10.14309/01.ajg.0000996032.89247.4e","DOIUrl":"https://doi.org/10.14309/01.ajg.0000996032.89247.4e","url":null,"abstract":"Background: There are few data on the quality-of-care for in fl ammatory bowel disease (IBD) in public, private or mixed hospitals. Aim: To evaluated clinic and quality parameters and their association with need for ICU and death in Brazilian hospitals. Methods: Multicentre study carried out in 26 hospitals including 488 admissions of patients with IBD were analyzed between June 2021 and October 2022. Results","PeriodicalId":188050,"journal":{"name":"The American Journal of Gastroenterology","volume":"70 7","pages":"S20 - S20"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138988641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}