Minerva dental and oral science最新文献

{"title":"Diagnostic approach for post-COVID-19 mucormycosis.","authors":"Ankita Mathur, Vishnu T Obulareddy, Praveen K Kamma, Sapna Negi, Snehasish Tripathy, Vini Mehta, Luca Fiorillo","doi":"10.23736/S2724-6329.25.05031-4","DOIUrl":"10.23736/S2724-6329.25.05031-4","url":null,"abstract":"<p><p>The COVID-19 pandemic, particularly in India, continues to pose a major threat to public health owing to the large number of patients that remain affected. The second wave of COVID-19 has brought with it several opportunistic diseases caused by bacteria and fungi, including mucormycosis, which is a well-known fungal infection primarily encountered in immunocompromised individuals through inhalation. In recent times, mucormycosis has become increasingly common in COVID-19 patients, particularly those with comorbidities such as diabetes, and has been observed to induce secondary infections as it spreads with COVID-19 treatment. Despite its importance, mucormycosis is still poorly studied due to the current priority given to research on treatments, vaccines, and diagnostics. To address this knowledge gap, this study aims to investigate the correlation between mucormycosis and COVID-19 patients and elucidate the molecular mechanism of mucormycosis to improve our understanding of fungal infections in patients who have recently contracted SARS-CoV-2.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"386-392"},"PeriodicalIF":1.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there a correlation between A, B, and O blood group system and dental anxiety in pediatric dental patients? An observational study.","authors":"Vritika Singh, Reema Sharma, Nikhil Marwah, Vipul Sharma, Maria Maddalena Marrapodi, Gabriele Cervino, Giuseppe Minervini","doi":"10.23736/S2724-6329.24.05064-2","DOIUrl":"10.23736/S2724-6329.24.05064-2","url":null,"abstract":"<p><strong>Background: </strong>Anxiety and fear are significant challenges in pediatric dentistry, often leading to avoidance of dental treatment. Some studies suggest a potential link between the dopamine beta-hydroxylase gene and the ABO gene. As ABO blood group type is determined genetically, it could serve as a bioindicator for assessing the impact of genetics on personality traits. The association between blood types and personality characteristics has long been debated.</p><p><strong>Methods: </strong>Eighty eligible children, meeting the inclusion criteria, were enrolled in the study. Blood group data were obtained from parents/guardians. Dental anxiety assessment was done using the RMS-Picture scale and pulse oximeter.</p><p><strong>Results: </strong>The collected data were analyzed statistically.</p><p><strong>Conclusions: </strong>The study found no correlation between dental anxiety and ABO blood grouping.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"349-354"},"PeriodicalIF":1.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The dentist's role in documenting and managing traumatic oral injuries: a narrative review of medico-legal implications.","authors":"Giorgia V Lacasella, Maria E Bizzoca, Andrea Ballini, Valentina Borgia, Francesca A Prencipe, Fabiola DE Tullio, Lucia DE Biasi, Pasquale Cupelli, Marialessia Rignani, Elisabetta Dimauro, Michele A Karaboue","doi":"10.23736/S2724-6329.25.05223-4","DOIUrl":"10.23736/S2724-6329.25.05223-4","url":null,"abstract":"<p><p>Traumatic oral injuries are frequently encountered in dental practice and may result from both accidental causes and intentional harm, including child abuse, intimate partner violence, and elder neglect. Dentists, due to their clinical expertise and regular patient contact, are often among the first healthcare providers to identify signs of non-accidental trauma. This narrative review explores the dentist's role in the detection, documentation, and medico-legal management of such injuries, particularly in the context of suspected abuse or neglect. A narrative review of relevant literature, clinical guidelines, and forensic protocols was conducted. Sources were selected based on their relevance to dental diagnosis, trauma recognition, medico-legal obligations, and interdisciplinary collaboration in suspected abuse cases. Certain injury patterns - such as contusions, lacerations, avulsions, and frenulum tears - especially in protected anatomical areas or with incongruent patient histories, may suggest inflicted trauma. Comprehensive clinical and photographic documentation is essential for legal and protective proceedings. Dentists must be familiar with mandatory reporting laws and recognize their legal responsibilities. Forensic odontologists contribute valuable expertise by providing objective injury analysis and supporting legal investigations. Multidisciplinary collaboration with pediatricians, general physicians, legal authorities, and social workers enhances case management and victim protection. Dentists have a dual responsibility: providing care and safeguarding vulnerable individuals. Strengthening dental education in forensic odontology, trauma-informed care, and medico-legal procedures is essential to prepare practitioners for this role. Increasing awareness and interprofessional communication can significantly improve outcomes in cases of traumatic oral injuries linked to abuse or neglect.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"405-412"},"PeriodicalIF":1.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144743138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the effect of aging on the shear bond strength between old composite resin restoration and the repair composite resin: an in-vitro study.","authors":"Hafiz A Adawi, Saurabh Jain, Ahmed O Shami, Hamood M Mahdali, Ali M Kaabi, Osama B Balki, Marco Cicciù, Giuseppe Minervini","doi":"10.23736/S2724-6329.24.04889-7","DOIUrl":"10.23736/S2724-6329.24.04889-7","url":null,"abstract":"<p><strong>Background: </strong>The current study aimed to evaluate the effect of aging on the repair bond strength between old composite resin and repaired composite resin and to evaluate which type of repair composite material provides better bond strength in different time durations.</p><p><strong>Methods: </strong>Eighty nano-hybrid composite specimens were randomly divided into four groups (N.=20) and exposed to accelerated aging from 0 to 2 years. Each group was further divided into two subgroups, A and B, repaired with packable and flowable composite respectively, after micro-abrasion treatment. Shear bond strength was assessed and statistically analyzed.</p><p><strong>Results: </strong>It was observed that with an increase in aging time, the bond strength of both the composite materials used for repair decreased. The flowable composite's mean bond strength (22.09±0.65, 18.74±2.36, and 17.74±2.38 MPa) was more than the packable composite (21.97±0.84, 17.97±3.85, and 15.97±2.45 MPa) used for repair on aged specimens. In contrast, the bond strength of the packable was more than the flowable composite in control group specimens that were not aged (23.25±0.89 vs. 22.40±1.26).</p><p><strong>Conclusions: </strong>As restored composites age, their bond strength decreases. Flowable composite displays better repair shear strength than packable composite as aging progresses. Micro abrasion followed by flowable composite bonding can repair aged composite restorations effectively.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"291-298"},"PeriodicalIF":1.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence in dentistry: a narrative review of applications, challenges, and future directions.","authors":"Michele DI Cosola, Andrea Ballini, Francesca A Prencipe, Fabiola DE Tullio, Anna Fabrocini, Pasquale Cupelli, Marialessia Rignani, Angela P Cazzolla, Maria E Bizzoca, Gennaro Musella","doi":"10.23736/S2724-6329.25.05217-9","DOIUrl":"10.23736/S2724-6329.25.05217-9","url":null,"abstract":"<p><p>Artificial intelligence (AI) is increasingly influencing dental practice, offering advancements in diagnostics, treatment planning, and patient management. This narrative review explores the current applications of AI in dentistry, addressing clinical, technological, and ethical dimensions. A non-systematic narrative approach was employed to synthesize recent literature on AI in dentistry. The focus was on diagnostic tools, treatment planning, decision support systems, teledentistry, ethical implications, and emerging technologies. AI demonstrates high performance in image analysis (e.g., caries detection, periodontal assessment, oral cancer screening), treatment optimization (e.g., orthodontics, implant planning), and patient-specific risk modeling. Clinical decision support systems (CDSS) assist in evidence-based care, while AI-driven chatbots and remote monitoring platforms enhance patient engagement and access. However, challenges persist regarding algorithm transparency, data bias, legal liability, and privacy. Future directions include multimodal data integration, digital twins, and AI-driven precision dentistry. AI represents a paradigm shift in dentistry, supporting clinicians and enabling more accurate, accessible, and personalized care. Successful implementation will depend on ethical deployment, robust regulation, and adequate training to harness its full potential without compromising professional standards.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"337-348"},"PeriodicalIF":1.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing medical students' awareness of the link between oral and systemic health: a questionnaire-based study in a cohort of year 3 and 4 MBBS students in the UK.","authors":"Flavio Pisani, Gennaro Musella, Fozan Ashfaq, Alessandro Motta, Vito C A Caponio, Maria E Bizzoca, Lorenzo Lo Muzio, Andrea Ballini, Kathryn Taylor","doi":"10.23736/S2724-6329.25.05199-X","DOIUrl":"10.23736/S2724-6329.25.05199-X","url":null,"abstract":"<p><strong>Background: </strong>Oral health is crucial for overall well-being, as conditions like periodontitis are increasingly associated with systemic diseases, including type 2 diabetes, cardiovascular diseases, and neurological disorders. Research in the UK and globally has revealed limited awareness among medical students about these connections, emphasizing the need for curriculum enhancements. This study assessed the awareness of year 3 and 4 medical students about oral-systemic disease connections.</p><p><strong>Methods: </strong>Following approval from the University of Central Lancashire School of Medicine and Dentistry Ethics Committee, a cross-sectional questionnaire-based survey was conducted. The survey, consisting of multiple-choice questions with multiple answer options, was delivered anonymously via an internal Teams channel to a representative cohort of year 3 and 4 medical students. The questionnaire covered general awareness of oral-systemic health, specific oral disease knowledge, and a focused evaluation of the periodontitis-diabetes relationship. Statistics included descriptive analysis and Chi-square Tests to assess associations between responses. Measures of association, such as Phi and Cramér's V, were also calculated.</p><p><strong>Results: </strong>A total of 122 students participated (65.67% year 3, 34.33% year 4). Most (91.04%) acknowledged the link between oral and general health. While 80.6% identified periodontitis as gum disease, 8.96% associated it with tooth decay, and 10.45% were unaware. Awareness of the bidirectional relationship with diabetes was limited; 60% recognized that diabetes increases periodontitis risk, but only 29.9% understood the reverse.</p><p><strong>Conclusions: </strong>This study highlights gaps in medical students' knowledge of oral-systemic health, emphasizing the need for better integration of oral health education in the medical curriculum. Aligning with WHO strategies and European Federation of Periodontology initiatives, improved interprofessional education can enhance patient care through collaboration between medical and dental professionals.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"328-336"},"PeriodicalIF":1.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are the dermatological cut-off values of commercially available ELISAs for BP180-NC16A appropriate when applied for diagnosis of oral mucous membrane pemphigoid?. Results of a preliminary study.","authors":"Andrea Gabusi, Federica Filippi, Camilla Loi, Lucio Montebugnoli, Cosimo Misciali, Davide B Gissi, Federico Bardazzi","doi":"10.23736/S2724-6329.25.05004-1","DOIUrl":"10.23736/S2724-6329.25.05004-1","url":null,"abstract":"<p><strong>Background: </strong>Enzyme-linked immunosorbent assay (ELISA) kits for BP180-NC16A use different cutoff levels established for cutaneous bullous pemphigoid (BP). However, in oral mucous membrane pemphigoid (OMMP), circulating antibodies are reported to be less readily detectable than cutaneous BP and there is little evidence that these cut-off levels are suitable for OMMP. This study was performed to explore whether the available cutoff values of anti-BP180-NC16A ELISA used for cutaneous BP are equally effective when applied to OMMP or should benefit from an optimized cut-off value.</p><p><strong>Methods: </strong>Eighty-one patients with oral blistering diseases were divided into two groups based on the results of histological and direct immunofluorescence analyses: the OMMP group (N.=31) and the non-OMMP control group (N.=50). Antibodies against BP180-NC16A were evaluated using manufacturer's cutoff level (Euroimmun 20 U/mL). A preliminary cutoff specific for BP180 in OMMP was identified by receiver operator characteristic (ROC) curve analysis.</p><p><strong>Results: </strong>A cutoff value of 20 U/mL showed low sensitivity (41.94%) but high specificity (94%). Using ROC curve analysis, a cutoff of 11 U/mL emerged as the optimal cutoff for BP180-OMMP (sensitivity: 70.97%; specificity: 88.7%). Using both cutoff values false-positives cases emerged (pemphigus vulgaris and oral lichen planus).</p><p><strong>Conclusions: </strong>The BP180-NC16A ELISA cutoff values designed for cutaneous BP may not be equally accurate when applied for the diagnosis of OMMP. The use of cut-off values specific for OMMP and a panel of several antigens specific for OMMP may improve the clinical utility of ELISAs; however, problems deriving from low specificity should be acknowledged.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"299-306"},"PeriodicalIF":1.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the crestal bone expansion obtained with the Magnetic Mallet® during the preparation of the implant site: a case series.","authors":"Domenico Baldi, Jacopo Colombo, Elena Cassinotto, Francesco Bagnasco, Luisa DE Giorgis, Francesca Baldi, Tadeusz Morawiec, Paolo Pesce, Maria Menini","doi":"10.23736/S2724-6329.25.05106-X","DOIUrl":"10.23736/S2724-6329.25.05106-X","url":null,"abstract":"<p><strong>Background: </strong>The purpose of the study is to evaluate the use of a magnetodynamic instrument (Magnetic Mallet^®, Metaergonomica, Turbigo, Milan, Italy) to perform a horizontal bone expansion in edentulous sites that need to be rehabilitated with a dental implant.</p><p><strong>Methods: </strong>A sample of 15 patients, 11 men and 4 women, age between 39 and 78 years, was analyzed. A total of 18 conical-shaped implants with a diameter of 3.80 mm and a length between 10 and 11.5 mm were inserted in the maxillary region in the area between the lateral incisor and the first upper molar. The patients were treated by two different surgeons. Bone thickness was measured through CBCT before treatment and at 3 months post-surgery.</p><p><strong>Results: </strong>No implant failed and all of them achieved a correct osseointegration. The average pre-surgery bone thickness was 4.36±0.70 mm, it changed to 5.58±1.11 mm after using the Magnetic Mallet^®, finally stabilized at 6.72±1.24 mm with the insertion of the implant. CBCT examination revealed a statistically significant difference in mean bone thickness before treatment and at 3 months post-surgery with a mean bone thickness of respectively 4.39±0.60 mm and 6.97±1.25 mm. Significantly different outcomes were obtained by operators with a different learning curve.</p><p><strong>Conclusions: </strong>At 3 months of follow-up, the Magnetic Mallet^® proved to be a useful tool in the horizontal expansion of the atrophic upper jaw bone crest, along with the preparation of the implant site. A learning curve is necessary to optimize the clinical outcomes. Further studies are needed with a larger patient cohort and a longer follow-up to confirm the present results.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"318-327"},"PeriodicalIF":1.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apex locators in endodontics: in-vivo comparison between different devices and radiographic method.","authors":"Enzo Cumbo, Giuseppe Gallina, Pietro Messina, Giuseppe A Scardina","doi":"10.23736/S2724-6329.25.05077-6","DOIUrl":"10.23736/S2724-6329.25.05077-6","url":null,"abstract":"<p><strong>Background: </strong>The precise measurement of the working length (WL) is pivotal for the success of endodontic treatments. Incorrect WL determination can lead to improper reaming and filling of the canal, posing risks of periradicular pathologies onset or failure to heal pre-existing conditions. Presently, apex locators are commonly used for WL determination, available in a variety of characteristics and costs. Alternatively, the traditional method using intraoral radiography remains prevalent.</p><p><strong>Methods: </strong>This study, conducted partly in vivo and partly in vitro, on teeth designated for extraction, compares three WL measurement methods: 1) radiographic method (zero cost); 2) Apex Locator (inexpensive); and 3) Root ZX II (expensive). The correctness of measurements was verified through visual inspection under a stereomicroscope.</p><p><strong>Results: </strong>Our data indicate that the precision of apex locators surpasses that of the radiographic method, which relies on visual inspection of the instrument inside the canal and is subject to personal interpretations of the images. No significant differences in precision were observed between the two locators examined, despite their differing price ranges and brand histories in the field of endodontics.</p><p><strong>Conclusions: </strong>Among the multitude of parameters influencing a dentist's choice of electro-medical equipment, cost remains a significant consideration, particularly when equipment exhibits similar characteristics.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"307-317"},"PeriodicalIF":1.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Forensic odontology: a comprehensive review of advances and applications in dental forensic medicine.","authors":"Giorgia V Lacasella, Luca Signorini, Andrea Ballini, Maria E Bizzoca, Gennaro Musella, Eleonora Lo Muzio, Nunzio Cirulli, Elisabetta Dimauro, Michele A Karaboue","doi":"10.23736/S2724-6329.25.05187-3","DOIUrl":"10.23736/S2724-6329.25.05187-3","url":null,"abstract":"<p><p>Forensic odontology is essential in medico-legal investigations, aiding in the identification of individuals, particularly in cases involving decomposed or severely damaged remains. Teeth, due to their durability and uniqueness, serve as critical forensic markers. This field also plays a role in age estimation, bite mark analysis, and legal disputes related to dental malpractice. Key forensic dental techniques include comparative dental analysis, radiographic imaging, and DNA extraction from teeth, which offer resistance to environmental degradation. Advanced methods such as aspartic acid racemization, radiocarbon dating, and histological analysis further enhance age estimation accuracy. Bite mark impressions, though controversial, remain relevant in forensic investigations. Additionally, forensic odontology collaborates with anthropology, botany, and entomology to strengthen identification processes. Technological advancements, including digital forensic tools, 3D imaging, and improved DNA analysis, have enhanced the precision of forensic dental identification. Bite mark analysis, while debated, benefits from computer-assisted comparisons. Forensic dentists are increasingly involved in legal cases, particularly in dental malpractice disputes, requiring specialized knowledge to assess liability and damages. Forensic odontology continues to evolve, integrating innovative technologies to improve accuracy and efficiency. Future research will focus on refining identification methods, utilizing AI-driven forensic analysis, and addressing ethical concerns related to DNA usage. Expanding forensic dental expertise in both clinical and legal contexts will be crucial for maintaining the discipline's role in forensic science.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"273-290"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}