Minerva cardiology and angiology最新文献

{"title":"Prevalence and features of coronary ectasia: an angiographic study.","authors":"Esma Cetinkaya, Fahri Er, Senem Şaş, Ayşe Taş","doi":"10.23736/S2724-5683.24.06652-3","DOIUrl":"https://doi.org/10.23736/S2724-5683.24.06652-3","url":null,"abstract":"<p><strong>Background: </strong>In the morphology of coronary arteries, changes such as atherosclerosis and ectasia occur over time. The aim of this study is to identify the factors influencing changes in coronary artery morphology.</p><p><strong>Methods: </strong>One hundred twenty-seven patients were evaluated of their baseline characteristics, echocardiography findings, laboratory values, and screening for systemical diseases. Patients were divided into three groups. Group N: the group with normal coronary arteries. Group A: the group with atherosclerosis. Group E: the group with ectasia and/or aneurysm. Mann-Whitney U Test and Kruskal Wallis Test were used in analysis of measurement data that did not conform to the normal distribution.</p><p><strong>Results: </strong>Diabetes mellitus, hypertension, and chronic kidney disease were found to be statistically significantly higher in Group A. The mean TAPSE/sPAP ratio in Group A patients is lower than in Group E and normal individuals (P<0.001) Vasculitis is more frequently observed in Group E (13.3%) compared to Group A. The frequency of at least one musculoskeletal disease in rheumatologic screening in Group A (100.0%) and in Group E (100.0%) is higher than in the Group N (69.8%) (P<0.001) CONCLUSIONS: No specific risk factor or disease was identified in this study that increases the frequency of coronary artery ectasia. However, diabetes mellitus, hypertension, chronic kidney disease, and low ejection fraction were found to be significantly associated with atherosclerosis.</p>","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143492929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review and meta-analysis investigating gender differences in in-hospital, short-term and long-term outcomes among patients who underwent primary PCI.","authors":"Iva Patel, Pooja Vyas, Anand Shukla, Pratik Shah, Deepanshu Assudani, Khushboo Chauhan","doi":"10.23736/S2724-5683.24.06670-5","DOIUrl":"https://doi.org/10.23736/S2724-5683.24.06670-5","url":null,"abstract":"<p><strong>Introduction: </strong>To assess how gender disparities impact major adverse cardiovascular events during hospitalization, as well as in the short and long term, among patients with ST-elevation myocardial infarction who undergo primary PCI.</p><p><strong>Evidence acquisition: </strong>PubMed, Scopus and Cochrane database were searched for relevant studies. Studies were included if all comers with STEMI, reported gender specific patient characteristics, treatments and outcomes. Odds ratio and 95% confidence interval were calculated using random effect model.</p><p><strong>Evidence synthesis: </strong>A total of 23 studies were included for the pooled meta-analysis. Average age of female at presentation was 68.61±3.91 years while in male was 60.83±2.48 years. In unadjusted analysis, female patients were at higher risk for mortality (OR=1.98, 95% CI: 1.71-2.30, P<0.0001, I²=35%) at hospitalization, (OR=2.25, 95% CI=1.75-2.88, P≤0.00001) at short term and (OR=1.76, 95% CI: 1.41-2.21, P<0.000, I²=68%) at long term. The adjusted analysis of major adverse cardiovascular events for short term (OR=1.09, 95% CI: 0.91-1.31, P=0.37, I²=76%) and long term (OR=1.05, 95% CI: 0.98-1.12, P=0.17, I²=37%) were not found significant between both genders. However, it remained significant during hospitalization (OR=1.12, 95% CI: 1.03-1.22, I²=15%, Tau²=0.00).</p><p><strong>Conclusions: </strong>The findings of this comprehensive meta-analysis indicate higher major adverse cardiac events among women with STEMI who underwent PPCI. After adjusting for comorbidities, the difference between women and men showed insignificant at short term and long term but remained significant at in-hospital. Female patients exhibited a higher prevalence of cardiovascular risk factors than men. Implementing intensive cardiovascular risk reduction strategies in women may offer a pathway to address this gender disparity.</p>","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atrial refractoriness early after transcatheter aortic valve implantation TAVI in patients with severe aortic stenosis and sinus rhythm.","authors":"Özcan Özdemir, Onur Yildirim","doi":"10.23736/S2724-5683.24.06540-2","DOIUrl":"10.23736/S2724-5683.24.06540-2","url":null,"abstract":"<p><strong>Background: </strong>Aortic valve stenosis (AS) is a common valvular heart disease, especially in the elderly, and is associated with a high prevalence of atrial fibrillation. Although the risk of atrial fibrillation is expected to decrease after the intervention, atrial fibrillation develops in many patients undergoing surgical or percutaneous transaortic valve implantation. We aimed to evaluate atrial refractoriness since it may play a key role in the occurrence of atrial fibrillation after transaortic valve implantation.</p><p><strong>Methods: </strong>Seventy-nine consecutive patients who underwent TAVI between October 2021 and May 2023 were enrolled in this trial. Sixty-seven patients underwent electrophysiology study before and after TAVI. We evaluated the changes in PA and AH intervals, as well as atrial effective refractory periods.</p><p><strong>Results: </strong>Besides the hemodynamic changes, atrial effective refractory periods increased, and atrial effective refractory period dispersion (39.8±21.6 vs. 31.1±18.0) decreased significantly after TAVI. The change in atrial effective refractory period dispersion after TAVI was correlated only with the changes in left ventricular end-diastolic pressure (r=0.77, P=0.001) and the changes in aortic gradient (r=0.4, P=0.001). The independent variables affecting the changes in atrial effective refractory period dispersion were basal pro-BNP levels, besides the changes in left ventricular end-diastolic pressure and aortic gradient after transaortic valve implantation.</p><p><strong>Conclusions: </strong>Our results show an acute improvement in atrial refractoriness after TAVI, though high atrial fibrillation rates are reported in the literature. The timing of aortic valve replacement is important, as irreversible maladaptive changes might have already developed by the time of intervention.</p>","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":"113-119"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142350100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified Medina Trifurcation Score: a new tool to predict outcomes of unprotected distal left main trifurcation percutaneous coronary intervention.","authors":"Andrea Marrone, Monica Verdoia, Alfonso Ielasi","doi":"10.23736/S2724-5683.24.06676-6","DOIUrl":"10.23736/S2724-5683.24.06676-6","url":null,"abstract":"","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":"73-76"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142951422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Dietary Inflammatory Index (DII) and sarcopenia in ischemic heart disease: an 1999-2004 NHANES study of 1088 US individuals.","authors":"Xiao-Yun Zheng, Yi Chen, Yan Gao, Mo Zhou, Wen-Zhuo Guan","doi":"10.23736/S2724-5683.24.06496-2","DOIUrl":"10.23736/S2724-5683.24.06496-2","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to investigate the relationship between DII and sarcopenia in individuals with ischemic heart disease (IHD).</p><p><strong>Methods: </strong>This was a retrospective study utilizing data of the National Health and Nutrition Examination Survey (NHANES) from 1999-2004. Adults aged ≥50 years diagnosed with IHD, having complete 24-hour dietary recall data, and dual energy X-ray absorptiometry (DEXA)-measured muscle mass were eligible for inclusion. Association between DII and sarcopenia, defined by reduced appendicular skeletal muscle mass, was determined by the logistic regression analyses.</p><p><strong>Results: </strong>Data of 1088 individuals were analyzed, with the mean age of 68.1±0.5 years. Significantly higher DII was observed in the sarcopenic group compared to the non-sarcopenic group (0.24 vs. -0.17, P=0.020). After adjusting for relevant confounders in the multivariable analysis, each unit increase in DII was significantly associated with higher odds of sarcopenia (adjusted odd ratio [aOR]=1.07, 95% confidence interval: 1.00-1.14, P value = 0.040). In stratified analyses, among patients with a Body Mass Index (BMI) ≥30 kg/m², both DII tertile 2 and tertile 3 were significantly associated with greater odds of sarcopenia (tertile 2 vs. tertile 1: aOR=2.85, 95% CI: 1.56-5.23, P=0.001; tertile 3 vs. tertile 1: aOR=3.11, 95% CI: 1.53-6.31, P=0.002), whereas no significant associations was observed among patients with a BMI<30 kg/m².</p><p><strong>Conclusions: </strong>This study has established a significant independent association between a higher DII and an increased risk of sarcopenia in US adults with IHD regardless of type of IHD. BMI appears as a moderating factor in this association.</p>","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":"65-72"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frailty in chronic heart failure: a multidimensional assessment of older patients undergoing cardiac rehabilitation.","authors":"Nicolò Granata, Martina Vigorè, Raffaella Vaninetti, Roberto Maestri, Roberta Borri, Angelo Caporotondi, Giancarlo Piaggi, Gioele Cremonese, Antonia Pierobon","doi":"10.23736/S2724-5683.24.06555-4","DOIUrl":"10.23736/S2724-5683.24.06555-4","url":null,"abstract":"<p><strong>Background: </strong>Chronic heart failure (CHF) is often associated with cognitive, psychological, and functional disorders. In addition, since patients suffering from this condition are often older adults, the presence of frailty could worsen the clinical situation.</p><p><strong>Methods: </strong>The present multicentric observational study aimed to investigate, through a multidimensional evaluation, the associations between clinical, functional, cognitive, psychological, and frailty variables of older (age ≥65) CHF inpatients undergoing cardiac rehabilitation and to identify the eventual independent predictors of the frailty status.</p><p><strong>Results: </strong>The study included 85 patients (mean age 73.88±5.84). The disease severity of the sample was moderate (left ventricular ejection fraction = 41.79±15.40). Among the patients, 32.94% had cognitive impairment, 12.94% and 14.11% reported moderate to severe anxious or depressive symptoms, respectively, and 34.12% were classified as frail (Clinical Frailty Scale [CFS] score ≥5). The CFS score showed a negative correlation with cognitive status (Addenbrooke's Cognitive Examination III [ACE III] [r=-0.48, P≤0.0001] and Frontal Assessment Battery [FAB] [r=-0.33, P=0.0001]) and functional status (Short Physical Performance Battery [SPPB] [r=-0.55, P≤0.0001] and Barthel Index [r=-0.52, P≤0.0001]), while showing a positive correlation with comorbidities (Cumulative Illness Rating Scale [CIRS] [r=0.40, P≤0.0001]). The stepwise regression analysis revealed that ACE III, SPPB, and CIRS were independent predictors of frailty status (CFS).</p><p><strong>Conclusions: </strong>Frailty is an important variable that should be considered since it is linked with most of the variables that play a role in the management and outcomes of older CHF patients and, thus, its evaluation should be integrated into the usual assessment in cardiac rehabilitation.</p>","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":"120-128"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebrovascular events after perioperative paroxysmal atrial fibrillation in patients undergoing aortic valve replacement.","authors":"Andrew Cassar, Gabriella Montanaro, Bettina Booker, Mark A Sammut, Alexander Manche, Joseph F Galea","doi":"10.23736/S2724-5683.24.06551-7","DOIUrl":"10.23736/S2724-5683.24.06551-7","url":null,"abstract":"<p><strong>Background: </strong>Postoperative atrial fibrillation (POAF) is common after aortic valve replacement (AVR). However, the long-term risk of cerebrovascular ischemic events (CVA) associated with POAF in this scenario is not known. The study objective was to look at the long-term risk of stroke in patients undergoing AVR with POAF compared to those with no POAF, particularly in patients having a bioprosthetic valve and not discharged on anticoagulation. We also looked at the risk of peri-operative stroke and long-term mortality.</p><p><strong>Methods: </strong>A retrospective study of 831 patients undergoing AVR were followed up for a median of 6.5 years. The primary outcome was the occurrence of CVA after discharge, comparing those with to those without POAF, after excluding patients with a past history of atrial fibrillation (AF). They were divided into two cohorts, those having bioprosthetic valves (without oral anticoagulation), and those with a mechanical valve (with oral anticoagulation). Other outcomes studied were the incidence of early perioperative CVA comparing patients with a history of AF to those with no history, and long-term mortality in the different cohorts.</p><p><strong>Results: </strong>There was no increased risk of long-term stroke in patients with POAF when compared to those without POAF, neither in bioprosthetic valves (adjusted HR 1.14; CI 95% 0.46-2.83, P=0.78)-nor in mechanical valves (adjusted HR 1.41; CI 95% 0.55-3.65, P=0.48). Patients with a history of AF had an increased risk of perioperative stroke (OR 1.5; CI 95% 1.3-13.8, P=0.01).</p><p><strong>Conclusions: </strong>Patients undergoing bioprosthetic AVR who develop POAF are not at an increased risk of stroke despite not being on any oral anticoagulation.</p>","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":"95-103"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tribute to Prof. Alessandro Santo Bortone.","authors":"Emanuela De Cillis, Martino Pepe, Antonio Gaglione, Vincenzo Pestrichella, Alfredo Marchese, Filippo Masi, Fortunato Iacovelli, Gaetano Contegiacomo, Elia Iorio, Nicola Signore, Giuseppe Colonna, Arturo Giordano, Giancarlo Piccinni, Andrea I Guaricci, Marco M Ciccone","doi":"10.23736/S2724-5683.24.06749-8","DOIUrl":"10.23736/S2724-5683.24.06749-8","url":null,"abstract":"","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":"1-3"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is vitamin D a new target for patients with acute coronary syndrome and diastolic dysfunction?","authors":"Rita Pavasini, Monica Verdoia","doi":"10.23736/S2724-5683.24.06766-8","DOIUrl":"10.23736/S2724-5683.24.06766-8","url":null,"abstract":"","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":"54-56"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low vitamin D levels are associated with impaired diastolic function in patients with acute coronary syndrome.","authors":"Engin Algül, Nail B Özbeyaz, Haluk F Şahan, Faruk Aydinyilmaz, Aslan Erdoğan, Muhammed Erzurum, Hamza Sunman, Tolga H Efe, Özcan Özdemir","doi":"10.23736/S2724-5683.24.06515-3","DOIUrl":"10.23736/S2724-5683.24.06515-3","url":null,"abstract":"<p><strong>Background: </strong>Vitamin D deficiency is a common clinical picture associated with poor cardiovascular prognosis. It is also associated with impaired diastolic dysfunction in stable coronary artery disease. We investigated the relationship between vitamin D levels and diastolic dysfunction in patients with acute coronary syndrome (ACS).</p><p><strong>Methods: </strong>One hundred seventeen patients with the ACS were enrolled in this cross-sectional study. The diastolic function of the patients was evaluated using echocardiography before discharge. We analyzed the relation between serum levels of 25(OH)D and echocardiographic measures of diastolic dysfunction.</p><p><strong>Results: </strong>IVRT and E/e' were found to be significantly greater in patients with low vitamin D levels (115.48±13.64 vs. 106.88±14.80 ms, P<0.05; 10.19±2.80 vs. 8.1±3.2, P<0.05). When regression tests were performed, it was shown that vitamin D level was a predictor (OR=0.935, 95% CI: 0.886-0.987; P=0.015) and independent risk factor (OR=0.942, 95% CI: 0.888-0.998; P=0.042) for the development of diastolic dysfunction.</p><p><strong>Conclusions: </strong>We found that low vitamin D levels are associated with impaired diastolic function in patients with ACS with preserved left ventricular systolic function.</p>","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":"57-64"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}