MMWR. Morbidity and mortality weekly report最新文献

{"title":"Trends in Cervical Precancers Identified Through Population-Based Surveillance - Human Papillomavirus Vaccine Impact Monitoring Project, Five Sites, United States, 2008-2022.","authors":"Julia W Gargano, Ruth Stefanos, Rebecca M Dahl, Jessica L Castilho, Erica A Bostick, Linda M Niccolai, Ina U Park, Sheelah Blankenship, Monica M Brackney, Kameny Chan, Emily L Delikat, Sara Ehlers, Kimberly Gonzalez Barrera, RaeAnne Kurtz, James I Meek, Erin Whitney, Marissa Vigar, Elizabeth R Unger, Lauri E Markowitz","doi":"10.15585/mmwr.mm7406a4","DOIUrl":"10.15585/mmwr.mm7406a4","url":null,"abstract":"<p><p>In 2006, human papillomavirus (HPV) vaccine was first recommended in the United States to prevent cancers and other diseases caused by HPV; vaccination coverage increased steadily through 2021, and increasing numbers of young women had received HPV vaccine as children or adolescents. Since 2008, CDC has monitored incidence of precancerous lesions (cervical intraepithelial neoplasia [CIN] grades 2-3 and adenocarcinoma in situ [AIS], collectively CIN2+), which are detected through cervical cancer screening and can be used as an intermediate outcome for monitoring vaccination impact, via the five-site Human Papillomavirus Vaccine Impact Monitoring Project. This analysis describes trends in incidence of CIN2+ and CIN3+ (i.e., CIN grade 3 and AIS) lesions during 2008-2022. Among women aged 20-24 years who were screened for cervical cancer, rates during 2008-2022 decreased for CIN2+ by 79%, and for CIN3+ by 80%. In the same period, CIN3+ rates among screened women aged 25-29 years decreased by 37%. These data are consistent with considerable impact of HPV vaccination for preventing cervical precancers among women in the age groups most likely to have been vaccinated, and support existing recommendations to vaccinate children at the routinely recommended ages as a cancer prevention measure.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 6","pages":"96-101"},"PeriodicalIF":25.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Notes from the Field: Genomic and Wastewater Surveillance Data to Guide a Hepatitis A Outbreak Response - Los Angeles County, March 2024-June 2024.","authors":"Jordan B Braunfeld, Bonnie L Dao, Justin Buendia, Raiza Amiling, Cierra LeBlanc, Mirna P Jewell, Hannah Henry, Giorgio Cosentino, Prabhu Gounder","doi":"10.15585/mmwr.mm7405a3","DOIUrl":"10.15585/mmwr.mm7405a3","url":null,"abstract":"","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 5","pages":"66-68"},"PeriodicalIF":17.3,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly Pathogenic Avian Influenza A(H5N1) Virus Infection of Indoor Domestic Cats Within Dairy Industry Worker Households - Michigan, May 2024.","authors":"Ramya Naraharisetti, Meghan Weinberg, Becky Stoddard, Mary Grace Stobierski, Kimberly A Dodd, Nora Wineland, Mathew Beal, Jennifer Morse, Samantha Hatter, Dodd Sledge, Katelynn Youatt, Joseph Coyle, Jevon McFadden, Timothy M Uyeki, Lizette O Durand","doi":"10.15585/mmwr.mm7405a2","DOIUrl":"10.15585/mmwr.mm7405a2","url":null,"abstract":"<p><p>Highly pathogenic avian influenza (HPAI) A(H5N1) virus, clade 2.3.4.4b, genotype B3.13 infection has been documented in cats on U.S. dairy cattle farms. In May 2024, the detection of HPAI A(H5N1) virus infection in two cats that were reported to be exclusively indoor, and that had respiratory and neurologic illness in different households, prompted an investigation by the Michigan Department of Health and Human Services and Mid-Michigan District Health Department (MDHHS/MMDHD). The cats' owners and household members were interviewed and offered testing for influenza A(H5) virus. The owner of one cat worked on a dairy farm but declined A(H5) testing; three other household members received negative A(H5) test results. The owner of the other cat lived alone and worked on multiple dairy farms transporting unpasteurized milk; this worker also reported getting splashed in the face and eyes by unpasteurized milk but declined A(H5) testing. Both workers were employed in a county known by MDHHS/MMDHD to have HPAI A(H5N1) virus, clade 2.3.4.4b, genotype B3.13-positive dairy cattle. In states with confirmed HPAI A(H5N1) in livestock, veterinary care can be aided if veterinarians obtain household members' occupational information, especially when evaluating cats with signs of respiratory or neurologic illness. If occupational exposure to HPAI A(H5N1)-infected livestock is identified among cat owners, and their companion cats are suspected to have HPAI A(H5N1) virus infection, it is important that veterinarians contact state and federal public health and animal health officials to collaborate on joint One Health investigations and testing to protect human and animal health.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 5","pages":"61-65"},"PeriodicalIF":17.3,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dengue Outbreak and Response - Puerto Rico, 2024.","authors":"Fhallon Ware-Gilmore, Dania M Rodriguez, Kyle Ryff Mph, Jomil M Torres, Miladys Perez Velez, Cristhian T Torres-Toro, Gilberto A Santiago, Aidsa Rivera, Zachary J Madewell, Yashira Maldonado, Iris Cardona-Gerena, Grayson C Brown, Laura E Adams, Gabriela Paz-Bailey, Melissa Marzán-Rodriguez","doi":"10.15585/mmwr.mm7405a1","DOIUrl":"10.15585/mmwr.mm7405a1","url":null,"abstract":"<p><p>Dengue, a mosquitoborne viral infection, is a public health threat in Puerto Rico, where multiple dengue virus (DENV) serotypes circulate. Dengue causes an acute febrile illness that can progress to severe disease or death. The last outbreak declared by the Puerto Rico Department of Health occurred during 2013. In January 2024, the number of dengue cases in Puerto Rico surpassed the epidemic threshold and remained elevated, prompting the Puerto Rico Department of Health to declare a public health emergency in March 2024. In collaboration with CDC, a dengue outbreak response was initiated to monitor the outbreak and implement vector-control measures alongside public health campaigns to raise awareness about increasing dengue case numbers and strategies to prevent mosquito bites. During 2024, a total of 6,291 confirmed dengue cases were reported; the highest numbers of cases were reported in the municipalities of San Juan (1,200; 17.3%), Carolina (354; 5.1%), and Rincón (252; 3.6%). DENV serotype 3 predominated, accounting for 59.2% of cases with known serotype. Approximately one half of ill patients (52.3%) required hospitalization, with the highest percentages of hospitalizations (33.9%) and severe dengue cases (28.4%) occurring among persons aged 10-19 years. Overall, severe dengue was identified in 4.2% of cases, with 11 reported fatalities (0.2%). Transmission remains elevated in multiple regions, underscoring the need for tailored public health measures, including vaccination among eligible populations, vector management, community outreach, and provider education to facilitate improved outcomes. To reduce the risk for mosquito bites, residents of and visitors to Puerto Rico should consider using repellents, wearing protective clothing, and staying in places with door and window screens.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 5","pages":"54-60"},"PeriodicalIF":17.3,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Notes from the Field: Elevated Atmospheric Lead Levels During the Los Angeles Urban Fires - California, January 2025.","authors":"Haroula D Baliaka, Ryan X Ward, Roya Bahreini, Ann M Dillner, Armistead G Russell, John H Seinfeld, Richard C Flagan, Paul O Wennberg, Nga L Ng","doi":"10.15585/mmwr.mm7405a4","DOIUrl":"10.15585/mmwr.mm7405a4","url":null,"abstract":"","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 5","pages":"69-71"},"PeriodicalIF":17.3,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First Clade Ib Monkeypox Virus Infection Reported in the Americas - California, November 2024.","authors":"Vivian Levy, Anna Branzuela, Kristina Hsieh, Shiffen Getabecha, Ricardo Berumen, Kayla Saadeh, Robert E Snyder, Gillian Marek, Daniel Dodson, Alyssa Newman, Jill K Hacker, Chantha Kath, Faisal S Minhaj, Crystal M Gigante, Shannon Gearhart, Alexander Kallen, Christina L Hutson, Kathleen Jacobson","doi":"10.15585/mmwr.mm7404a1","DOIUrl":"10.15585/mmwr.mm7404a1","url":null,"abstract":"<p><p>A clade I monkeypox virus (MPXV) outbreak is ongoing in the Democratic Republic of the Congo; travel-associated clade I MPXV infections have been reported in non-African countries. In November 2024, San Mateo County Health in California identified an electronic laboratory report of polymerase chain reaction results suggestive of clade I MPXV infection in a male traveler who had recently returned from East Africa. After conferring with the California Department of Public Health (CDPH), a county health department worker visited the patient that same day at his home and obtained skin pustule swab specimens for expedited clade I MPXV testing. Clade I MPXV was confirmed the following day by the CDPH Viral and Rickettsial Disease Laboratory. This was the first reported clade I MPXV infection in the Americas. Among 83 identified contacts, five received JYNNEOS vaccine as postexposure prophylaxis. All contacts were monitored for 21 days; no secondary cases were identified. Patients with mpox-compatible lesions or clinical features should receive MPXV testing, and health care providers should immediately notify public health authorities of suspected clade I MPXV infections (e.g., mpox manifestations and travel history to an area with ongoing clade I MPXV transmission) or upon receiving a nonvariola orthopoxvirus DNA detected, clade II MPXV DNA undetectable test result to trigger additional testing and facilitate the rapid implementation of transmission-based precautions and other preventive public health interventions.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 4","pages":"44-49"},"PeriodicalIF":25.4,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11824946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143414666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Notes from the Field: Seroprevalence of Highly Pathogenic Avian Influenza A(H5) Virus Infections Among Bovine Veterinary Practitioners - United States, September 2024.","authors":"Jerome Leonard, Elizabeth J Harker, Christine M Szablewski, Sara F Margrey, K Fred Gingrich, Keyana Crossley, Emily Fletcher, Claire J McCreavy, Sabrina Weis-Torres, Dennis Wang, Emma K Noble, Min Z Levine, H Pamela Pagano, Crystal Holiday, Feng Liu, Stacie Jefferson, Zhu-Nan Li, F Liaini Gross, Carrie Reed, Sascha Ellington, Alexandra M Mellis, Samantha M Olson","doi":"10.15585/mmwr.mm7404a2","DOIUrl":"10.15585/mmwr.mm7404a2","url":null,"abstract":"","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 4","pages":"50-52"},"PeriodicalIF":25.4,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11824947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143414668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Notes from the Field: Emergency Department Use During the Los Angeles County Wildfires, January 2025.","authors":"Emily Kajita, Karen Chang, Vannalyn de Leon, Wesley Moss, Michael Lim, Sharon Balter, Annabelle de St Maurice","doi":"10.15585/mmwr.mm7403a2","DOIUrl":"10.15585/mmwr.mm7403a2","url":null,"abstract":"","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 3","pages":"40-42"},"PeriodicalIF":25.4,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Notes from the Field: Serum Concentrations of Perfluoroalkyl and Polyfluoroalkyl Substances Among First Responders to the Maui Wildfires - Hawaii, September 2023.","authors":"Catherine C Beaucham, Rachel Zeiler, Kenneth Fent, Sophia K Chiu, Nicholas Somerville, Alexander Mayer, Jessica L Rinsky, Cheryl Estill","doi":"10.15585/mmwr.mm7403a1","DOIUrl":"10.15585/mmwr.mm7403a1","url":null,"abstract":"","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 3","pages":"35-39"},"PeriodicalIF":25.4,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advisory Committee on Immunization Practices Recommended Immunization Schedule for Adults Aged 19 Years or Older - United States, 2025.","authors":"A Patricia Wodi, Anindita N Issa, Charlotte A Moser, Sybil Cineas","doi":"10.15585/mmwr.mm7402a3","DOIUrl":"10.15585/mmwr.mm7402a3","url":null,"abstract":"<p><p>At its October 2024 meeting, the Advisory Committee on Immunization Practices* (ACIP) approved the Recommended Immunization Schedule for Adults Ages 19 Years or Older, United States, 2025. The schedule supports health care providers, as well as public health and other professionals, by providing a consolidated summary of current ACIP recommendations for adult vaccination. The 2025 schedule includes several updates to the cover page, tables, notes, and appendix.^† The addendum remains part of the schedule and will be used to summarize new or updated ACIP recommendations that occur before the next annual schedule update. Health care providers are strongly encouraged to use all parts of the schedule (the cover page, tables, notes, appendix, and addendum) together when making recommendations for individual patients. The 2025 adult immunization schedule can be found on the CDC website (https://www.cdc.gov/vaccines/hcp/imz-schedules/index.html).</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 2","pages":"30-33"},"PeriodicalIF":25.4,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11737654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143008147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}