MMWR. Morbidity and mortality weekly report最新文献

{"title":"Notes from the Field: Case of Legionnaires Disease Associated with a Home Device Used to Mix Powdered Infant Formula - United States, 2025.","authors":"Eric J Stern, Judie Hyun, Elizabeth J Hannapel, Melisa Willby, Chris Edens","doi":"10.15585/mmwr.mm7523a1","DOIUrl":"10.15585/mmwr.mm7523a1","url":null,"abstract":"","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"75 23","pages":"297-299"},"PeriodicalIF":16.2,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13277664/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148277954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Risk to the U.S. Population from the Ebola Disease Outbreak Caused by Bundibugyo Virus, 2026.","authors":"Danielle M Richard, Isobel Routledge, Sarah Koeller, Isaac Ghinai, Christopher H Hsu, Kevin Chatham-Stephens, Beau B Bruce, Rebecca Kahn, Inga Holmdahl","doi":"10.15585/mmwr.mm7522e2","DOIUrl":"10.15585/mmwr.mm7522e2","url":null,"abstract":"<p><p>On May 15, 2026, the ministries of health in the Democratic Republic of the Congo and Uganda declared outbreaks of Bundibugyo virus disease (BVD), a type of Ebola disease. In response to reports of high numbers of suspected cases and deaths in the affected countries, CDC assessed the risk posed by the BVD outbreak to the U.S. population during the next 3 months. This analysis used a standardized risk assessment approach that included epidemiologic data from the ongoing outbreak and historical data from previous Ebola outbreaks; the overall risk was determined by taking into account independent assessments of the likelihood of infection and the impact of infection. The assessment found that the overall risk to the U.S. population posed by the current BVD outbreak during the next 3 months is low, based on the extremely low likelihood of transmission, despite the high impact that potential infection could have and the resources that would be required to respond to the outbreak. Limitations to this assessment included uncertainties around the epidemiology of BVD as well as the current and future scope and geographic spread of the outbreak. CDC continues to monitor factors that could change this risk assessment.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"75 22","pages":"290-292"},"PeriodicalIF":16.2,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13258049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148226493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Legionnaires Disease Associated with a Private-Use Hot Tub in a Vacation Rental Property - New York, October 2024-April 2025.","authors":"Matthew Morse, Martin Zartarian, Braden Savage, Patrick O'Connor, David Nicholas, Halex Jones, Christopher Gil, Danielle Wroblewski, Stacey Chmura, Nirupam Biswas, Craig Bocketti, Grace Willard, Seth Blumerman, Theresa Hattenrath, Donna Gowie, Lisa Mingle, Ursula Lauper","doi":"10.15585/mmwr.mm7522a1","DOIUrl":"10.15585/mmwr.mm7522a1","url":null,"abstract":"<p><p>In mid-October 2024, the New York State Department of Health (NYSDOH) was notified of two cases of Legionnaires disease in persons who stayed at the same short-term vacation rental property and had both used the rental property's hot tub. The diagnoses were confirmed by urine antigen tests, and NYSDOH successfully isolated Legionella pneumophila serogroup 1 from the sputum of one patient. Local health department staff members collected three samples from three sinks and two samples from two showers to assess the rental property's potable water system, which was supplied by a private well. Three samples were also collected from the rental property's hot tub. Whole genome sequencing of isolates from the hot tub samples and the sputum specimen were closely related, suggesting that the hot tub was the likely source of exposure. Hot tubs create aerosols and typically maintain water temperatures of approximately 100°F-104°F (38°C-40°C). This temperature is within the most favorable range for Legionella growth and also accelerates the decay of disinfectants. Guidance from NYSDOH and CDC regarding proper operation, disinfection, and remediation of hot tubs was provided to the rental property owner. NYSDOH recommended that the owner close the hot tub until proper remediation was performed and postremediation samples without detection of any Legionella bacteria were collected by NYSDOH staff members. The rental property owner did not initially comply with NYSDOH recommendations, and a public nuisance law was used to ensure that proper measures were taken to disinfect the hot tub before use by future guests. Activities to raise awareness among short-term rental and vacation rental property owners regarding the risks associated with an improperly managed hot tub are needed to decrease the likelihood that rental property hot tubs are in a condition that is conducive to Legionella growth and reduce the risk for Legionnaires disease associated with vacation rental stays. Travelers staying in vacation rental properties should be aware that use of hot tubs might pose a risk for Legionnaires disease and exercise caution when using hot tubs, particularly those travelers with underlying medical conditions.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"75 22","pages":"274-279"},"PeriodicalIF":16.2,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13292786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148226503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Notes from the Field: Outbreak of Ebola Disease Caused by Bundibugyo Virus - Democratic Republic of the Congo and Uganda, May 2026.","authors":"Delayo L Zomahoun, Mary Adetinuke Boyd, Margaret A Honein, Joel M Montgomery, Emily Zielinski-Gutierrez, Elissa Meites, Athalia Christie, Satish K Pillai","doi":"10.15585/mmwr.mm7522e3","DOIUrl":"10.15585/mmwr.mm7522e3","url":null,"abstract":"","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"75 22","pages":"293-294"},"PeriodicalIF":16.2,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13257930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148226561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modeled Scenario Projections for the Ebola Disease Outbreak Caused by Bundibugyo Virus, 2026.","authors":"Eric Q Mooring, William T Koval, Isobel Routledge, Inga Holmdahl, Kate Hudson, Guido España, Rebecca Kahn, Beau B Bruce","doi":"10.15585/mmwr.mm7522e1","DOIUrl":"10.15585/mmwr.mm7522e1","url":null,"abstract":"<p><p>On May 15, 2026, the Ministries of Health in the Democratic Republic of the Congo and Uganda declared outbreaks of Bundibugyo virus disease (BVD), a type of Ebola disease. In response to reports of high numbers of suspected cases and deaths in these outbreaks, CDC simulated scenario projections to understand possible future morbidity and mortality. A branching process model with the capacity to model transmission-reducing nonpharmaceutical interventions was calibrated to three putative cumulative death counts and projected for four possible intervention scenarios ranging from poor (20%) to extremely high (95%) levels of isolation and treatment of symptomatic persons. The analysis suggested a plausible spillover event (i.e., the transmission of a virus from its natural animal reservoir to humans) in mid to late February 2026. With poor isolation levels of patients with BVD (20%) and no other interventions, the likelihood of an outbreak that exceeds 20,000 cases within 3 months is 65%. If, however a high proportion of patients were to enter isolation (70%), only a one in 20 chance is projected for an outbreak with ≥10,000 cases within 3 months. These results underscore the importance of strong public health interventions, because the current outbreak is already the largest known BVD outbreak and has the potential to quickly become one of the largest Ebola disease outbreaks ever recorded.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"75 22","pages":"285-289"},"PeriodicalIF":16.2,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13257927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148226553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alcohol Consumption During Pregnancy Among Women Aged 18-49 Years - United States, 2021-2024.","authors":"Shawn A Thomas, Lucas K Gosdin, Mishka Terplan, Shin Y Kim, Nicholas P Deputy","doi":"10.15585/mmwr.mm7522a2","DOIUrl":"10.15585/mmwr.mm7522a2","url":null,"abstract":"<p><p>Alcohol consumption during pregnancy can cause adverse birth outcomes and fetal alcohol spectrum disorders. One U.S. study identified a slight increasing trend in alcohol consumption during pregnancy from 2011 to 2018. During 2018-2020, 13.5% of pregnant women reported current drinking; more recent estimates are unavailable. CDC analyzed 2021-2024 Behavioral Risk Factor Surveillance System data to estimate prevalence of self-reported current drinking (one or more alcoholic drinks during the past 30 days), binge drinking (four or more alcoholic drinks on at least one occasion during the past 30 days), and heavy drinking (eight or more alcoholic drinks within 1 week during the past 30 days) among U.S. pregnant women aged 18-49 years. Multivariable regression was used to estimate adjusted prevalence ratios and identify correlates of alcohol consumption during pregnancy. Among U.S. pregnant women, 15.2% reported current drinking, 4.9% reported binge drinking, and 2.2% reported heavy drinking during the past 30 days. Higher prevalences of alcohol consumption were observed among pregnant women who were not married and those with frequent mental distress. Alcohol consumption during pregnancy remains a public health concern. Both clinical and community interventions might help reduce alcohol consumption during pregnancy and its associated adverse health outcomes.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"75 22","pages":"280-284"},"PeriodicalIF":16.2,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13257928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148226428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"QuickStats: Age-Adjusted Colorectal Cancer Death Rates,* by State - United States, 2024.","authors":"","doi":"10.15585/mmwr.mm7522a3","DOIUrl":"10.15585/mmwr.mm7522a3","url":null,"abstract":"","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"75 22","pages":"295"},"PeriodicalIF":16.2,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13257926/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148226578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Notes from the Field: Borrelia mayonii Lyme Disease - New York, 2025.","authors":"Tanvir Noor Nafiz, Melissa A Prusinski, Sai Gubbala, Jennifer White, Dowd Naik, Jamie Sommer, Danielle Wroblewski","doi":"10.15585/mmwr.mm7521a2","DOIUrl":"10.15585/mmwr.mm7521a2","url":null,"abstract":"","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"75 21","pages":"271-272"},"PeriodicalIF":16.2,"publicationDate":"2026-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13235943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148163785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measles Outbreak in a Child Care Facility - Lubbock, Texas, March-April 2025.","authors":"Anh N Ly, Amanda Shotts, Tiffany Torres, Georgina Peacock, David E Sugerman, Carolyn Crisp, Gretchen Rodriguez, Thi Dang, Diana Martinez, Saroj Rai, Varun Shetty, Ashley Meehan, Susan Hocevar Adkins, Thomas D Filardo, Nicole F Dowling, Katherine Wells","doi":"10.15585/mmwr.mm7521a1","DOIUrl":"10.15585/mmwr.mm7521a1","url":null,"abstract":"<p><p>During 2025, the United States recorded the highest number of measles cases since measles elimination was declared in 2000. On March 21, 2025, Lubbock Public Health (LPH) in Texas received a report of a child care attendee aged 3 years, with fever, rash, cough, coryza, conjunctivitis, otitis media, and diarrhea who received a positive test result for measles by real-time reverse transcription-polymerase chain reaction (RT-PCR). Six additional children who attended the same child care facility and the grandfather of one of the children were confirmed by RT-PCR testing to have measles. None of the patients was reported to have traveled. LPH contacted the pediatric patients' caregivers to conduct case investigations and provided recommendations to the child care facility for home isolation, vaccination, and testing. LPH also communicated with caregivers, other child care facilities in the area, and the public to raise awareness. The child care facility implemented measures to minimize transmission, including separating children who were not yet eligible for the measles, mumps, and rubella vaccine; minimizing the use of shared spaces; and monitoring signs and symptoms. Collaboration between public health and community partners such as child care facilities can facilitate a rapid response and control of infectious disease outbreaks.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"75 21","pages":"266-270"},"PeriodicalIF":17.3,"publicationDate":"2026-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148163780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amanita Species Mushroom Poisonings - Northern California, November 2025-March 2026.","authors":"Kevin J Brandecker, Chelsea Hayman, Kathy T LeSaint, Rais Vohra, Asha Choudhury, M Elizabeth Marder, Russell Bartlett, Tracy Barreau, Craig G Smollin","doi":"10.15585/mmwr.mm7520a2","DOIUrl":"10.15585/mmwr.mm7520a2","url":null,"abstract":"<p><p>The genus Amanita contains approximately 600 species of mushrooms, including some that produce amatoxins, which can lead to liver failure and death when ingested. Poisonous mushrooms often resemble and are difficult to distinguish visually from nonpoisonous, edible mushrooms. After above-average late November 2025 rainfall in California, regional mycologists observed numerous Amanita mushroom blooms in regional parks and area wildlands. On November 18, 2025, specialists at the San Francisco division of the California Poison Control System (CPCS) suspected amatoxin-containing mushroom poisoning in two patients who gastrointestinal symptoms and hepatotoxicity after eating foraged wild mushrooms. Over the next 17 weeks (November 18, 2025-March 17, 2026), 39 cases of suspected amatoxin mushroom poisoning in patients who had eaten foraged wild mushrooms were reported to CPCS. These 39 cases were characterized by a pattern of delayed onset of gastrointestinal symptoms and hepatotoxicity; 32 (82%) patients recovered, three (8%) required liver transplants, and four (10%) died. CPCS and the California Department of Public Health Toxicological Outbreak Program coordinated a response that included a statewide health advisory and educational materials translated into multiple languages for the public; collectively, the affected patients spoke at least six languages other than English. This is the largest reported outbreak of mushroom-associated hepatotoxic poisoning in California history and the largest in the United States in several decades. This was also the first outbreak of this size in which some persons ate Amanita ocreata, another poisonous Amanita species. The morbidity and potential lethality associated with amatoxin-containing mushroom ingestion is a serious public health concern. Educational materials, including for non-English-speaking communities, during the late fall to mid-spring when fruiting of amatoxin-containing mushrooms occurs, might reduce the number of poisonings.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"75 20","pages":"258-263"},"PeriodicalIF":16.2,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13218420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148055563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}