Minerva obstetrics and gynecology最新文献

{"title":"Association of high expression of CD44 in clinicopathological factors of endometrial cancer.","authors":"Gina M Riana, Nugraha U Pelupessy, Sriwijaya Qadar, Upik Miskad, Andi A Zainuddin, Fatmawati Madya, Efendi Lukas","doi":"10.23736/S2724-606X.23.05279-X","DOIUrl":"10.23736/S2724-606X.23.05279-X","url":null,"abstract":"<p><strong>Background: </strong>Clinical stages, histologic type, degree of cell differentiation, myometrial invasion, and lymph-vascular space invasion (LVSI) have been identified as clinicopathological factors that are predictive for endometrial cancer, however, further prognostic indicators are still required to account for the heterogeneity of this cancer. Adhesion molecule CD44, affects the invasion, metastasis, and prognosis of many forms of cancer. The purpose of this study is to examine the expression of CD44 in endometrial cancer and its correlation with established prognostic variables.</p><p><strong>Methods: </strong>A cross-sectional study was conducted on 64 samples of endometrial cancer from Wahidin Sudirohusodo Hospital and Hasanuddin University Hospital. Immunohistochemical analysis was used to detect CD44 expression using mouse anti-human CD44 monoclonal antibody. Differences in Histoscore were studied to determine the association between CD44 expression and clinicopathological factors of endometrial cancer.</p><p><strong>Results: </strong>Of the overall sample, 46 samples were in the early stage, whereas 18 samples were in the advanced stage. High expression of CD44 was associated with advanced stage compare than early stage (P=0.010), poor differentiation compare than well-moderate differentiation (P=0.001), myometrial invasion ≥50% compare than myometrial invasion <50% (P=0.004), and positive LVSI compare than negative LVSI (P=0.043) in endometrial cancer, but not associated with histological type of endometrial cancer (P=0.178).</p><p><strong>Conclusions: </strong>High expression of CD44 may be considered as a poor prognostic marker and predictive marker for targeted therapy in endometrial cancer.</p>","PeriodicalId":18572,"journal":{"name":"Minerva obstetrics and gynecology","volume":" ","pages":"410-415"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9091350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetal hyperechogenic pancreas and gestational diabetes mellitus: a meta-analysis.","authors":"Megan K Taylor, Giovanni Sisti","doi":"10.23736/S2724-606X.23.05341-1","DOIUrl":"10.23736/S2724-606X.23.05341-1","url":null,"abstract":"<p><strong>Introduction: </strong>Gestational diabetes mellitus is the most common metabolic disorder in pregnancy, and it is associated with detrimental short- and long-term consequences to both the fetus and the mother. Some studies in the literature have found an association between the identification of fetal hyperechogenic pancreas via prenatal ultrasound and the presence of gestational diabetes mellitus. The aim of our study was to assess the association of fetal hyperechogenic pancreas with gestational diabetes mellitus using the meta-analytic method.</p><p><strong>Evidence acquisition: </strong>We searched electronic databases for articles describing association (or lack of) between fetal hyperechogenic pancreas and gestational diabetes mellitus. For each study, we identified patients with or without fetal hyperechogenic pancreas and with or without gestational diabetes mellitus. We then calculated risk ratios for gestational diabetes mellitus using the meta-analytic Mantel-Haenszel method with a random effect to estimate the risk ratio.</p><p><strong>Evidence synthesis: </strong>We identified 286 patients in 2 studies. The risk ratio of gestational diabetes mellitus in women with fetal hyperechogenic pancreas was 3.34, P<0.0001 (95% CI, 1.56-7.17; I²=82% [95% CI 22.7-95.7%]).</p><p><strong>Conclusions: </strong>The presence of a fetal hyperechogenic pancreas was associated with gestational diabetes mellitus. We concluded that the detection of fetal pancreas echogenicity may be a promising indicator of gestational diabetes mellitus that, pending further research studies, can potentially help the clinician in making this diagnosis.</p>","PeriodicalId":18572,"journal":{"name":"Minerva obstetrics and gynecology","volume":" ","pages":"452-457"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50158318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical features and their associations with umbilical cord gas abnormalities.","authors":"Allison Payne, Gianna Wilkie, Katherine Leung, Heidi Leftwich","doi":"10.23736/S2724-606X.24.05482-4","DOIUrl":"10.23736/S2724-606X.24.05482-4","url":null,"abstract":"<p><strong>Background: </strong>We seek to identify risk factors associated with abnormal umbilical artery cord gas (UACG).</p><p><strong>Methods: </strong>This was a secondary analysis of the multicenter Consortium for Safe Labor dataset. This study included singleton, term deliveries with UACG available. Abnormal UACG was defined as pH≤7.0 or base excess >12 mmol/L. Odds Ratios were calculated using a multivariable logistic regression to determine clinical factors associated with abnormal UACG.</p><p><strong>Results: </strong>18,589 patients met inclusion criteria, with approximately 2% having an abnormal UACG. Those with prior Cesarean delivery (OR=1.49, 95% CI: 1.15-1.93), maternal diabetes (OR=1.67, 95% CI: 1.06-2.64), magnesium sulfate use (OR=1.81, 95% CI: 1.25-2.60), current Cesarean delivery (OR=2.56, 95% CI: 2.06-3.19), pre-eclampsia/HELLP (hemolysis, elevate liver enzymes, low platelet count) syndrome (OR=2.80, 95% CI: 1.79-4.36), and placental abruption (OR=4.81, 95% CI: 3.35-6.91) had increased odds of having abnormal UACG at delivery compared to those without.</p><p><strong>Conclusions: </strong>Diabetes, pre-eclampsia, placental abruption, and a history of prior Cesarean delivery were all associated with abnormal UACG in this cohort of singleton, term deliveries. These findings indicate that patients with pre-existing risk factors may be at an increased likelihood of adverse neonatal outcomes.</p>","PeriodicalId":18572,"journal":{"name":"Minerva obstetrics and gynecology","volume":" ","pages":"437-443"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iron deficiency anemia in pregnancy and the postpartum: a practical approach by the Italian GOAL Working Group.","authors":"Giancarlo Paradisi, Laura Anelli, Francesco Barletta, Francesco A Battaglia, Michelangelo Boninfante, Marco Bonito, Roberto Brunelli, Franco Carboni, Brigida Carducci, Annafranca Cavaliere, Mario Ciampelli, Giulio DE Matteis, Davide DE Vita, Michele Desiato, Antonio DI Cioccio, Romolo DI Iorio, Sergio Ferrazzani, Alessandro Lena, Francesca Lippa, Patrizia Magliocchetti, Francesco Maneschi, Marina Marceca, Emanuela Marinoni, Roberto Marzilli, Valerio Napolitano, Giorgio Nicolanti, Mino Oliva, Pierluigi Palazzetti, Carlo Piscicelli, Antonio Ragusa, Pietro Saccucci, Giovanna Salerno, Giovanbattista Serra, Fabrizio Signore, Vincenzo Spina, Herbert Valensise, Rossana Orabona, Antonio Lanzone","doi":"10.23736/S2724-606X.24.05438-1","DOIUrl":"10.23736/S2724-606X.24.05438-1","url":null,"abstract":"<p><strong>Background: </strong>Iron deficiency and iron deficiency anemia represent global health issues, particularly during pregnancy and the postpartum. The present paper aims to summarize the appropriate management of these conditions in order to try to improve how clinicians perceive, diagnose and treat iron deficiency and iron deficiency anemia.</p><p><strong>Methods: </strong>An expert panel of Italian obstetricians of Lazio region was convened to evaluate the available literature on iron deficiency and iron deficiency anemia during pregnancy and the post-partum in order to try to define a flow chart on the appropriate management of such conditions; aspects related to the patient blood management have also been investigated.</p><p><strong>Results: </strong>According to both hemoglobin level and ferritin values, five the flow charts on the appropriate management of iron deficiency and iron deficiency anemia have been drawn.</p><p><strong>Conclusions: </strong>It is desired to define appropriate flow charts to treat iron deficiency and iron deficiency anemia, which are too often not promptly diagnosed and managed, in order to try to improve antenatal care.</p>","PeriodicalId":18572,"journal":{"name":"Minerva obstetrics and gynecology","volume":"76 5","pages":"470-477"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current practices and perceptions of misoprostol use for cervical preparation prior to outpatient hysteroscopy: a nationwide survey among gynecologists in Spain.","authors":"Antonio Ramírez-Osuna, Encarnación Carmona-Sánchez, Nicolás Mendoza, Peter Chedraui","doi":"10.23736/S2724-606X.24.05521-0","DOIUrl":"10.23736/S2724-606X.24.05521-0","url":null,"abstract":"<p><strong>Background: </strong>Although misoprostol has been used as a potential option for cervical priming prior to hysteroscopy, the available scientific evidence regarding its use is not always conclusive. The purpose of this article is to assess the different practices and criteria applied for the use of misoprostol use for cervical preparation in outpatient hysteroscopy without anesthesia among gynecologists across Spain, exploring the need for the corresponding evidence-based guidelines.</p><p><strong>Methods: </strong>We carried out a cross-sectional study in which a two-step approach survey was conducted. Firstly, an online pilot survey was conducted with a limited sample of 10 professionals from 10 centers to identify initial patterns and gather feedback. Subsequently, a comprehensive online survey was carried out over a larger sample of respondents. The comprehensive survey covered aspects of misoprostol usage, including dosage, timing, indications, safety concerns, and overall perception. The survey design allowed for a thorough examination of existing practices and provided valuable insights to help address the disparities noted in misoprostol use for cervical preparation in outpatient hysteroscopies.</p><p><strong>Results: </strong>Through the comprehensive online survey, we received response of 102 gynecologists from 54 centers across Spain. The overall results show a considerable variation in misoprostol use prior to hysteroscopy, with 21.57% of respondents not using misoprostol in any case, while a substantial majority (78.43%) use it selectively (68.83%) or consistently (9.8%). When asked about the type of patients, the vast majority (72.55%) use it in postmenopausal nulliparous patients, while its was used considerably less in premenopausal nulliparous patients (35.29%), postmenopausal multiparous patients (22.55%), and premenopausal multiparous patients (3.92%), whereas some choose not to use it in any patients (26.47%). Furthermore, 89.22% of respondents felt that there is a lack of clear criteria on misoprostol use, while 79.41% believed that it is necessary to establish such criteria.</p><p><strong>Conclusions: </strong>There was a diverse landscape of misoprostol use which underscores the complexity and individual approach to cervical preparation for an outpatient hysteroscopy. Indeed, the findings regarding its application, notably more prevalent among postmenopausal patients, contravene the prevailing body of published evidence. Moreover, a considerable proportion of respondents expressed the need for clear criteria, which emphasizes the importance of evidence-based protocols to guide the optimal use of misoprostol.</p>","PeriodicalId":18572,"journal":{"name":"Minerva obstetrics and gynecology","volume":" ","pages":"403-409"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141419723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A prospective cohort study evaluating exclusive breastfeeding in late preterm infants.","authors":"Daniela Menichini, Katia Rossi, Eleonora Bonini, Maria L Deicco, Francesca Monari, Simona DI Mario, Alberto Berardi, Fabio Facchinetti, Isabella Neri","doi":"10.23736/S2724-606X.23.05411-8","DOIUrl":"10.23736/S2724-606X.23.05411-8","url":null,"abstract":"<p><strong>Background: </strong>Breastfeeding can be challenging in neonates born between 34 ^0/7 and 36 ^6/7 weeks gestation (late preterm).</p><p><strong>Methods: </strong>This prospective cohort study aims to evaluate exclusive breastfeeding at discharge, at three and six months of life in late preterm infants, and to identify facilitators and challenges to it. We included late preterm neonates eligible for the rooming-in. Data about breastfeeding at discharge, at three and six months of life were collected.</p><p><strong>Results: </strong>Two hundred and fourteen late preterm infants were included in the study. At discharge 70 infants (32.7%) were fed with human milk and 144 (67.2%) were not. Non-exclusive breastfeeding was more common in women who were primiparous, had hypertension, and who underwent cesarean sections. Non-exclusive breastfeeding was associated with a low birthweight (<2500 g), ≥2 blood glucose controls, weight loss >10%, and longer hospital stay. Early first latch-on and skin-to-skin contact were more frequently associated with exclusive human milk feeding (P<0.001). Late preterm neonates born at 35 weeks showed a significant increase in exclusive human milk feeding at 3 months compared to the rate at discharge (P=0.004).</p><p><strong>Conclusions: </strong>In this cohort, early first latch-on and immediate skin-to-skin contact resulted associated with exclusive human milk feeding. Despite formula-fed during hospitalization, infants born at ≥35 weeks gestation who were exclusively breastfed at follow-up increased.</p>","PeriodicalId":18572,"journal":{"name":"Minerva obstetrics and gynecology","volume":" ","pages":"423-430"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138445434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time to kiss goodbye the prolonged bladder catheterization after prolapse surgery.","authors":"Tala Kordiš, Ana Kofol, Mija Blaganje","doi":"10.23736/S2724-606X.23.05459-3","DOIUrl":"10.23736/S2724-606X.23.05459-3","url":null,"abstract":"","PeriodicalId":18572,"journal":{"name":"Minerva obstetrics and gynecology","volume":" ","pages":"478-479"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139735509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between decision and incision time by race and ethnicity.","authors":"Rodney Bruno, Gianna Wilkie, Julianne Lauring","doi":"10.23736/S2724-606X.24.05456-3","DOIUrl":"10.23736/S2724-606X.24.05456-3","url":null,"abstract":"<p><strong>Background: </strong>Identifying and reducing inequities in the delivery of care is crucial to improving health disparities in obstetric outcomes. This study sought to evaluate the effect of race and ethnicity on time from decision for cesarean delivery to incision following implementation of a case classification system.</p><p><strong>Methods: </strong>A retrospective cohort study was performed to identify women who had cesarean deliveries from October 1, 2020, to March 31, 2021, at a single, tertiary care institution. Medical records were reviewed for demographics and cesarean delivery case classification. Case classification was divided into STAT cesarean delivery (within 10 minutes), level A (within 30 minutes), level B (within 60 minutes), or scheduled/unscheduled other. The \"decision to incision time\" was determined from the time the case surgical order was placed to the case start time.</p><p><strong>Results: </strong>There were 565 eligible individuals who had a cesarean delivery during the study period, with 13.6% identifying as Black/African American, 29.0% as Hispanic/Latina, and 57.3% as White. Hispanic women were more likely to need interpreter services than other race/ethnicity groups. There was no statistically significant difference in \"decision to incision time\" by race/ethnicity. Within the total cohort, 51.8% of cesarean delivery cases went within the goal time according to case classification, which also did not differ by race/ethnicity.</p><p><strong>Conclusions: </strong>Race and ethnicity do not impact cesarean delivery \"decision to incision time\" or case classification. Only half of cesarean deliveries went within the goal time, so further evaluation to improve workflow and improve this metric for all patients is needed.</p>","PeriodicalId":18572,"journal":{"name":"Minerva obstetrics and gynecology","volume":" ","pages":"431-436"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140175489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antepartum pelvic floor muscle training (PFMT) plus perineal massage vs. postpartum PFMT alone: analysis of pelvic floor disorders, Quality of Life and sexual function.","authors":"Federica DI Pasquale, Alessia Contadini, Melania Loggia, Federica Sala, Debora Grilli, Lorenzo Campanella, Fabio Manganelli, Pier L Palazzetti, Herbert C Valensise, Michele C Schiavi","doi":"10.23736/S2724-606X.24.05466-6","DOIUrl":"https://doi.org/10.23736/S2724-606X.24.05466-6","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to analyze how antepartum pelvic floor muscle training (PFMT) plus perineal massage associated with postpartum PFMT have a significant impact on pelvic floor health during pregnancy and after delivery.</p><p><strong>Methods: </strong>One thousand two hundred thirty-three women were enrolled from January 2019 to December 2021. They were divided into two groups: 786 women underwent postpartum PFMT only, 447 women experienced both prepartum perineal massage and PFMT and postpartum PFMT. The primary endpoint was to evaluate prepartum perineal massage and PFMT's impact on delivery. The second endpoint was the evaluation of Quality of Life and sexual function at 3- and 12-months follow-up after delivery.</p><p><strong>Results: </strong>Women who underwent prepartum PFMT experienced significantly lower percentage of episiotomy, high-grade obstetric tear or instrumental delivery and higher percentage of intact perineum. Furthermore, prepartum PFMT appeared to improve sexual function at 3 months follow-up, and it was associated with an earlier first sexual intercourse after childbirth. The incidence of stress urinary incontinence was significantly higher in women who experienced PFMT only in postpartum, both at 3- and 12-months follow-up, while the other examined clinical parameters did not show a significant difference.</p><p><strong>Conclusions: </strong>Prepartum PFMT has a role in preventing obstetric traumas and on improving Sexual Function and Quality of Live in the immediate postpartum. Moreover, prepartum PFMT in association with postpartum PFMT reduces the incidence of stress urinary incontinence in a higher percentage than postpartum PFMT only.</p>","PeriodicalId":18572,"journal":{"name":"Minerva obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Induction of labor in high-risk nulliparous women with unfavorable cervix.","authors":"Valerio Carletti, Veronica Yacoub, Herbert C Valensise, Francesco Maneschi","doi":"10.23736/S2724-606X.24.05462-9","DOIUrl":"https://doi.org/10.23736/S2724-606X.24.05462-9","url":null,"abstract":"<p><strong>Background: </strong>Inducing labor by ensuring a good maternal-fetal outcome is a challenge. The aim of the study was to evaluate the success rate, safeness, and time to delivery after the induction of labor (IOL), with the alternately first use of dinoprostone or Foley balloon, in high-risk pregnancy nulliparous women with unfavorable Bishop Score (BS).</p><p><strong>Methods: </strong>This is a retrospective study of high-risk nulliparous women who underwent the IOL, either with dinoprostone or the Foley balloon method. In the former case, if the labor has not started after dinoprostone removal, oxytocin infusion started. In Foley group, the BS was re-evaluated after Foley removal, and IOL continued with the use of dinoprostone (if BS<6) or oxytocin (if BS>6). Here, too, if no labor occurred after dinoprostone removal, Oxytocin was administered. Delivery mode, fetal and maternal complications were recorded. The time to delivery was tracked.</p><p><strong>Results: </strong>A total of 261 women were enrolled in the study. The CS rate was similar between groups (37.56% vs. 35.93%; P=0.81). Time to delivery was statistically lower in dinoprostone group (26.82h), as opposed to Foley (47.4h) (P<0.0001). Body Mass Index (BMI) of women who underwent Cesarean section (CS) was significantly higher than women who gave birth by vaginal delivery (VD), 26.80 vs. 27.40, P=0.012.</p><p><strong>Conclusions: </strong>IOL in high-risk pregnancy nulliparous women resulted in equal rate of CS between the two groups. Dinoprostone first use resulted in a shorter time to delivery, with no maternal-fetal side effects. There is then no need to prolong IOL and raise maternal stress, as this will not yield better outcomes.</p>","PeriodicalId":18572,"journal":{"name":"Minerva obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142291097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}