Medical Gas Research最新文献_第2页

Hydrogen sulfide: an emerging gasotransmitter involved in the survival of pancreatic islets during diabetes therapy. 硫化氢：糖尿病治疗过程中与胰岛存活有关的一种新兴气体递质。

IF 3

Medical Gas Research Pub Date : 2025-03-01 Epub Date: 2024-10-02 DOI: 10.4103/mgr.MEDGASRES-D-24-00067

Udayakumar Karunakaran

引用次数: 0

Comparative study on the anti-inflammatory and protective effects of different oxygen therapy regimens on lipopolysaccharide-induced acute lung injury in mice. 不同氧疗方案对脂多糖诱发的小鼠急性肺损伤的抗炎和保护作用的比较研究。

IF 3

Medical Gas Research Pub Date : 2025-03-01 Epub Date: 2024-09-25 DOI: 10.4103/mgr.MEDGASRES-D-24-00044

Xinhe Wu, Yanan Shao, Yongmei Chen, Wei Zhang, Shirong Dai, Yajun Wu, Xiaoge Jiang, Xinjian Song, Hao Shen

{"title":"Comparative study on the anti-inflammatory and protective effects of different oxygen therapy regimens on lipopolysaccharide-induced acute lung injury in mice.","authors":"Xinhe Wu, Yanan Shao, Yongmei Chen, Wei Zhang, Shirong Dai, Yajun Wu, Xiaoge Jiang, Xinjian Song, Hao Shen","doi":"10.4103/mgr.MEDGASRES-D-24-00044","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00044","url":null,"abstract":"Oxygen therapy after acute lung injury can regulate the inflammatory response and reduce lung tissue injury. However, the optimal exposure pressure, duration, and frequency of oxygen therapy for acute lung injury remain unclear. In the present study, after intraperitoneal injection of lipopolysaccharide in ICR mice, 1.0 atmosphere absolute (ATA) pure oxygen and 2.0 ATA hyperbaric oxygen treatment for 1 hour decreased the levels of proinflammatory factors (interleukin-1beta and interleukin-6) in peripheral blood and lung tissues. However, only 2.0 ATA hyperbaric oxygen increased the mRNA levels of anti-inflammatory factors (interleukin-10 and arginase-1) in lung tissue; 3.0 ATA hyperbaric oxygen treatment had no significant effect. We also observed that at 2.0 ATA, the anti-inflammatory effect of a single exposure to hyperbaric oxygen for 3 hours was greater than that of a single exposure to hyperbaric oxygen for 1 hour. The protective effect of two exposures for 1.5 hours was similar to that of a single exposure for 3 hours. These results suggest that hyperbaric oxygen alleviates lipopolysaccharide-induced acute lung injury by regulating the expression of inflammatory factors in an acute lung injury model and that appropriately increasing the duration and frequency of hyperbaric oxygen exposure has a better tissue-protective effect on lipopolysaccharide-induced acute lung injury. These results could guide the development of more effective oxygen therapy regimens for acute lung injury patients.","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":" ","pages":"171-179"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular hydrogen gas and its therapeutic potential in recent disease progression. 分子氢气及其在近期疾病进展中的治疗潜力。

IF 3

Medical Gas Research Pub Date : 2025-03-01 Epub Date: 2024-09-25 DOI: 10.4103/mgr.MEDGASRES-D-24-00012

Md Habibur Rahman, Cheol-Su Kim, Kyu-Jae Lee

引用次数: 0

A narrative review of gas separation and conservation technologies during xenon anesthesia. 氙气麻醉过程中气体分离和保存技术综述。

IF 3

Medical Gas Research Pub Date : 2025-03-01 Epub Date: 2024-06-26 DOI: 10.4103/mgr.MEDGASRES-D-24-00002

Steven McGuigan, Brendan F Abrahams, David A Scott

{"title":"A narrative review of gas separation and conservation technologies during xenon anesthesia.","authors":"Steven McGuigan, Brendan F Abrahams, David A Scott","doi":"10.4103/mgr.MEDGASRES-D-24-00002","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00002","url":null,"abstract":"Xenon gas has significant advantages over conventional general anesthetic agents but its use has been limited by the cost associated with its production. Xenon also has significant potential for medical use in the treatment of acquired brain injuries and for mental health disorders. As the demand for xenon gas from other industries increases, the costs associated with its medical use are only likely to increase. One solution to mitigate the significant cost of xenon use in research or medical care is the conservation of xenon gas. During delivery of xenon anesthesia, this can be achieved either by separating xenon from the other gases within the anesthetic circuit, conserving xenon and allowing other gases to be excluded from the circuit, or by selectively recapturing xenon utilized during the anesthetic episode at the conclusion of the case. Several technologies, including the pressurization and cooling of gas mixtures, the utilization of gas selective membranes and the utilization of gas selective adsorbents have been described in the literature for this purpose. These techniques are described in this narrative review along with important clinical context that informs how these technologies might be best applied. Whilst these technologies are discussed in the context of xenon general anesthesia, they could be applied in the delivery of xenon gas inhalation for other therapeutic purposes.","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"93-100"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrogen sulfide: a rising star for cancer treatment. 硫化氢：治疗癌症的新星。

IF 3

Medical Gas Research Pub Date : 2025-03-01 Epub Date: 2024-08-02 DOI: 10.4103/mgr.MEDGASRES-D-24-00016

Zixin Wang, Yin Wang

引用次数: 0

Biological gases, oxidative stress, artificial intelligence, and machine learning for neurodegeneration and metabolic disorders. 生物气体、氧化应激、人工智能和机器学习，用于治疗神经退行性病变和代谢性疾病。

IF 3

Medical Gas Research Pub Date : 2025-03-01 Epub Date: 2024-10-02 DOI: 10.4103/mgr.MEDGASRES-D-24-00059

Kenneth Maiese

引用次数: 0

Fatigue disappearance in hemodialysis patients by dual approach with hydrogen gas inhalation and hydrogen-enriched dialysate: two case reports. 通过氢气吸入和富氢透析液双管齐下，血液透析患者疲劳消失：两例报告。

IF 3

Medical Gas Research Pub Date : 2025-03-01 Epub Date: 2024-06-26 DOI: 10.4103/mgr.MEDGASRES-D-24-00024

Ryoichi Nakazawa, Shintaro Nagami, Hiroshi Nozaki, Minako Yataka, Kazuhiro Akiyama, Takashi Uchino, Nakanobu Azuma

引用次数: 0

Nitric oxide-based treatments improve wound healing associated with diabetes mellitus. 基于一氧化氮的疗法可改善与糖尿病相关的伤口愈合。

IF 3

Medical Gas Research Pub Date : 2025-03-01 Epub Date: 2024-07-25 DOI: 10.4103/mgr.MEDGASRES-D-24-00020

Zahra Bahadoran, Parvin Mirmiran, Farhad Hosseinpanah, Khosrow Kashfi, Asghar Ghasemi

{"title":"Nitric oxide-based treatments improve wound healing associated with diabetes mellitus.","authors":"Zahra Bahadoran, Parvin Mirmiran, Farhad Hosseinpanah, Khosrow Kashfi, Asghar Ghasemi","doi":"10.4103/mgr.MEDGASRES-D-24-00020","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00020","url":null,"abstract":"Non-healing wounds are long-term complications of diabetes mellitus (DM) that increase mortality risk and amputation-related disability and decrease the quality of life. Nitric oxide (NO·)-based treatments (i.e., use of both systemic and topical NO· donors, NO· precursors, and NO· inducers) have received more attention as complementary approaches in treatments of DM wounds. Here, we aimed to highlight the potential benefits of NO·-based treatments on DM wounds through a literature review of experimental and clinical evidence. Various topical NO·-based treatments have been used. In rodents, topical NO·-based therapy facilitates wound healing, manifested as an increased healing rate and a decreased half-closure time. The wound healing effect of NO·-based treatments is attributed to increasing local blood flow, angiogenesis induction, collagen synthesis and deposition, re-epithelization, anti-inflammatory and anti-oxidative properties, and potent broad-spectrum antibacterial effects. The existing literature lacks human clinical evidence on the safety and efficacy of NO·-based treatments for DM wounds. Translating experimental favors of NO·-based treatments of DM wounds into human clinical practice needs conducting clinical trials with well-predefined effect sizes, i.e., wound reduction area, rate of wound healing, and hospital length of stay.","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"23-35"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Why provide 40 sessions of hyperbaric oxygen therapy to patients with traumatic brain injury? 为什么要为脑外伤患者提供 40 次高压氧治疗？

IF 3

Medical Gas Research Pub Date : 2025-03-01 Epub Date: 2024-09-25 DOI: 10.4103/mgr.MEDGASRES-D-24-00029

Cesar V Borlongan, Amir Hadanny

引用次数: 0

Carbon monoxide inhalation as a potential aid to enhance aerobic endurance. 将一氧化碳吸入作为增强有氧耐力的潜在辅助手段。

IF 3

Medical Gas Research Pub Date : 2025-03-01 Epub Date: 2024-08-31 DOI: 10.4103/mgr.MEDGASRES-D-24-00021

Bezuglov Eduard, Achkasov Evgeniy, Kapralova Elizaveta, Rudiakova Elizaveta, Shurygin Vladimir, Malyakin Georgiy, Sadkovaya Olga, Talibov Oleg, Baymeeva Natalia, Michail Vartapetov, Morgans Ryland

引用次数: 0