无创通气中的气体混合物。

IF 2.9 Q2 MEDICINE, RESEARCH & EXPERIMENTAL
Medical Gas Research Pub Date : 2026-03-01 Epub Date: 2025-06-28 DOI:10.4103/mgr.MEDGASRES-D-24-00129
Mostafa Elshazly, Garuti Giancario, Benan Bayrakci, Jose Luis Sandoval, Hebatallah Hesham Ahmed, Antonio M Esquinas
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引用次数: 0

摘要

无创通气(NIV)和高流量鼻插管越来越多地用于治疗急性呼吸衰竭。由于许多患者也可以从吸入药物中获益,因此将气溶胶治疗与NIV或高流量鼻插管相结合是一种很有前途的方法。有效的药物输送到肺部是成功的气溶胶治疗在NIV期间至关重要。先前的研究已经确定了影响NIV患者气溶胶输送效率的几个因素。医用气体在治疗各种呼吸系统疾病方面有着悠久的历史。其中,氧常用于缺氧患者(如低氧性呼吸衰竭和新生儿)。除了脱氧外,还可以通过面罩和NIV等设备进行氦氧混合物和一氧化氮的管理。本文旨在全面概述混合气体(如氦氧混合物和一氧化氮)在NIV中的应用,重点关注其在不同临床环境中的有效性、安全性和优化策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Gas mixture in noninvasive ventilation.

Noninvasive ventilation (NIV) and high-flow nasal cannula are increasingly used to treat acute respiratory failure. Because many of these patients could also benefit from inhaled medications, combining aerosol therapy with NIV or high-flow nasal cannula is a promising approach. Effective drug delivery to the lungs is crucial for successful aerosol therapy during NIV. Prior research has identified several factors that affect aerosol delivery efficiency in NIV patients. Medical gases have a long history of use in managing various respiratory conditions. Among them, oxygen is frequently used for patients with hypoxia (e.g., hypoxemic respiratory failure and in newborns). In addition to deoxygenation, helium oxygen mixture and nitric oxide can also be administered through devices such as masks combined with NIV. This narrative review aims to provide a comprehensive overview on the application of gas mixtures (such as helium oxygen mixtures and nitric oxide) in NIV, focusing on their efficacy, safety, and optimization strategies in different clinical settings.

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来源期刊
Medical Gas Research
Medical Gas Research MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
5.10
自引率
13.80%
发文量
35
期刊介绍: Medical Gas Research is an open access journal which publishes basic, translational, and clinical research focusing on the neurobiology as well as multidisciplinary aspects of medical gas research and their applications to related disorders. The journal covers all areas of medical gas research, but also has several special sections. Authors can submit directly to these sections, whose peer-review process is overseen by our distinguished Section Editors: Inert gases - Edited by Xuejun Sun and Mark Coburn, Gasotransmitters - Edited by Atsunori Nakao and John Calvert, Oxygen and diving medicine - Edited by Daniel Rossignol and Ke Jian Liu, Anesthetic gases - Edited by Richard Applegate and Zhongcong Xie, Medical gas in other fields of biology - Edited by John Zhang. Medical gas is a large family including oxygen, hydrogen, carbon monoxide, carbon dioxide, nitrogen, xenon, hydrogen sulfide, nitrous oxide, carbon disulfide, argon, helium and other noble gases. These medical gases are used in multiple fields of clinical practice and basic science research including anesthesiology, hyperbaric oxygen medicine, diving medicine, internal medicine, emergency medicine, surgery, and many basic sciences disciplines such as physiology, pharmacology, biochemistry, microbiology and neurosciences. Due to the unique nature of medical gas practice, Medical Gas Research will serve as an information platform for educational and technological advances in the field of medical gas.
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