Medical and Health Science Journal最新文献

{"title":"IMPLEMENTATION OF OCCUPATIONAL SAFETY AND HEALTH RISK MANAGEMENT IN ISLAMIC HOSPITAL SURABAYA A. YANI","authors":"Muhammad Huda Firmansyah","doi":"10.33086/mhsj.v5i2.2179","DOIUrl":"https://doi.org/10.33086/mhsj.v5i2.2179","url":null,"abstract":"Background: Risk management is a preventive effort for a company, especially those engaged in the service sector, which is very prone to errors and complaints. For this reason, it is necessary to map the risks that occur in accordance with the work unit in it which is expected to minimize the number of accidents or errors in both patients, visitors and employees in the hospital. In the 2019 patient safety incident report data at the Surabaya A. Yani Islamic Hospital, it was found that there were incidents which included near miss 93%, not injured 4%, unexpected events 3% and Sentinel 0%. The purpose of this study was to identify and identify the application of occupational safety and health risk management at the A. Yani Islamic Hospital in Surabaya.\u0000Methods: This thesis is a qualitative research with a case study method with the aim of fully describing the implementation of K3 risk management at Surabaya A. Yani Hospital based on observation, survey and documentation data on 37 units and hospital workplaces by identifying risks. , analyze and find risk control measures.\u0000Results: The results showed that the implementation of K3 risk management in the Islamic Hospital of Surabaya A. Yani based on the results of risk identification obtained as many as 25 risks in the graha building and the old building which were further analyzed by finding 15 moderate risks and 10 high risks. can be done is by repairing damaged infrastructure and improving the existing security system at the A. Yani Islamic Hospital in Surabaya.\u0000Conclusion: The conclusion in this study is the implementation of K3 risk management at the Islamic Hospital of Surabaya A. Yani based on the process of risk identification and risk analysis, there are 25 potential risks, of which there are 15 moderate risks and 10 high risks that can potentially cause accidents to employees, visitors and patients. In this case, control efforts are made to minimize the number of incidents and accidents.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80828827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PREDIKSI PERAN CURCUMINOID PADA CURCUMA LONGA SEBAGAI INHIBITOR GSK-3 TERHADAP PERTUMBUHAN DENTIN TERSIER","authors":"Naila Robbaniyya Fithriyya, Hanifah Nur Syafa, Dwi Cinthya Financia, Nadya Elsa Cahyaningrum, Husni Rama Wijayanti, Haidy Lailatun Nabila, Salma Kaltsum Kayana, Ghaida Humaira Susilo Putri, Nurul Hasanah Tanjung, Pratiwi Nur Widyaningsih, R. Purnama, Tirta Wardhana","doi":"10.20884/1.mhj.2021.1.1.4642","DOIUrl":"https://doi.org/10.20884/1.mhj.2021.1.1.4642","url":null,"abstract":"Caries is one of the most common oral diseases. Tertiary dentin regeneration has recently been developed as an alternative treatment for caries. Curcuminoids are known to have the ability to inhibit GSK-3β in the Wnt signalling pathway to accelerate the formation of reparative dentin. This study aimed to investigate curcuminoids as GSK-3β inhibitors in modulating tertiary dentin formation through the Wnt pathway. Insilico analysis has been carried out using an online database and software. Data collection is done through the Protein Data Bank https://www.rcsb.org/ dan PubChem https://pubchem.ncbi.nlm.here.gov/. The analysis of interactions between proteins and bioactive compounds through the STITCH website http://stitch.embl.de/ dan STRING https://string-db.org/.The results obtained that STK3 protein that binds to curcuminoids has a hippo signalling pathway that inhibits GSK-3β in the Wnt pathway. The study concludes that curcuminoids have the potential to accelerate the development of tertiary dentin.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76344261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"POTENTIAL COMPOUND EXTRACT FROM POTENTIAL COMPOUND EXTRACT FROM Carica pubescens ON GINGIVA INCISION WOUND HEALING: Through Proliferation, Differentiation and Immunoresponse Mechanisms","authors":"Salwa Az-Zahra, Sabrina Aulia Nurul Hidayah, Septina Nur Aini, Aprillya Yuniarni, Annisa Sukma Visanda, Asyyfa Devy, Amalia Putri Hesantera, Raja Ronaldo Siregar, Dicky Satria Ramadhan Basar, Pratiwi Nur Widyaningsih, R. B. Purnama, Tirta Wardana","doi":"10.20884/1.mhj.2021.1.1.4683","DOIUrl":"https://doi.org/10.20884/1.mhj.2021.1.1.4683","url":null,"abstract":"Luka menyebabkan gangguan struktur normal, sehingga penyembuhan luka dibutuhkan untuk perbaikan struktur sel dan jaringan. Beberapa sitokin dan growth factor yang memiliki peran penting pada proses penyembuhan luka diantaranya PDGF, FGF, TGF-β, VEGF, Angiopoetin, IL-1, IL-6, IL-10, TNF-α, IFN-γ, makrofag yang diproduksi oleh limfosit dan leukosit pada tahap sintetis kolagen. Daun papaya (Carica pubescens) diketahui memiliki kandungan flavonoid terdiri seperti apigenin, chyrsin, diosmetin, kaempferol, luteolin, naringenin dan quercetin yang berperan dalam meninkatkan ekspresi IL-10 untuk penyembuhan luka. Penelitian ini bertujuan untuk mengetahui kandungan senyawa dari Senyawa flavonoid Carica pubescens untuk meningkatkan kinerja IL-10. Penelitian ini dilakukan dengan menggunakan pendekatan bioinformatika menggunakan software web online server. Pencarian senyawa potensial didapatkan dari https://pubmed.ncbi.nlm.nih.gov/, senyawa kimia menggunakan http://www.pubchem.ncbi.nlm.nih.gov/ dengan struktur 3D. analisis prediksi bioaktivitas menggunakan http://stitch.embl.de/ dengan nilai indicator lebih dari 0.7 (Pa>0.7). Analisis ikatan kimia menggunakan http://stitch.embl.de/ dan http://string-db.org/. Analisis secara in silico menunjukkan bahwa senyawa kaemfrerol memiliki potensi meningkatkan kadar IL-10. Ditambah lagi, kami menemukan beberapa kandungan senyawa lainya yang berhubungan dengan penyembuhan luka seperti rutin, peroxynitrite, iloprost, quercetin. Pada penelitian ini, kami menyimpulkan bahwa senyawa kaempferol memiliki potensi sebagai alternative dalam pengembangan terapi untuk mempercepat penyembuhan luka.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"241 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76952445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PENGETAHUAN, SIKAP, DAN PERILAKU MAHASISWA KEDOKTERAN DAN KESEHATAN TERHADAP SKRINING GENETIK DAN PREMARITAL DI KABUPATEN BANYUMAS","authors":"Nouval Keandre, Lantip Rujito, Siti Munfiah","doi":"10.20884/1.mhj.2021.1.1.4670","DOIUrl":"https://doi.org/10.20884/1.mhj.2021.1.1.4670","url":null,"abstract":"","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86048851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role Of Tea Tree Oil as A Skin Antimicrobial : A Literature Study","authors":"Dian Ardiana","doi":"10.33086/MHSJ.V5I1.1921","DOIUrl":"https://doi.org/10.33086/MHSJ.V5I1.1921","url":null,"abstract":"Background: Skin disease due to microorganism infection are still widely found in community. The infections can be caused by bacteria, viruses, fungi, and parasite. Tea tree oil often used as a herbal medicine in the treatment of skin diseases due to microorganisms. This literature study is conducted to review the role of tea tree oil as an antimicrobial in skin infections.\u0000Method: Fifteen indexed journals published from 2015 to 2020 about tea tree oil and skin infections, were included. From 15 journals, 9 journals discuss antibacterial activity of tea tree oil, 2 journals discuss antiviral activity, 9 journals discuss antifungal activity, and 1 journal discusses antiparasitic activity. All journals state that tea tree oil has an antimicrobial effect on microorganisms that cause skin infections.\u0000Result: From 9 journals, it was found that A. baumanni, P. aeruginosa, and C. acnes were the most sensitive bacteria to tea tree oil in terms of MIC and S. epidermidis was the most sensitive bacteria, seen from their inhibition zone. Eight journals state variations with significant differences in the activity of tea tree oil as an anti-fungal. Tea tree oil has stronger antibacterial activity than antifungal activity. It also has antiviral activity against HSV and antiparasitic on S. scabiei.\u0000Conclusion: The conclusion of this study is that tea tree oil has antimicrobial activity against microorganisms that cause skin disease, including bacteria, viruses, fungi, and parasite.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"361 1","pages":"26-33"},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76475034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Tomate Juice On Trigliserida Levels Of Male White Rats Induced by Alloxan","authors":"Fitri Handajani, Ibrahim Shihatta","doi":"10.33086/MHSJ.V5I1.1740","DOIUrl":"https://doi.org/10.33086/MHSJ.V5I1.1740","url":null,"abstract":"Background: Tomato juice is believed to affect triglyceride levels in the blood because it contains lycopene. This study aims to determine the effect of tomato juice (Solanum lycopersicum) on blood triglyceride levels in the wistar strain of male Rattus norvegicus induced by alloxan.\u0000Methods: 24 were divided into 3 groups, (1) Group K (-) experimental animals without treatment, (2) Group K (+) experimental animals induced by alloxan 150 mg / kgBB, (3) Treatment group K (P) animals tried alloxan induced 150 mg / kg and got 1.75 ml / head of tomato juice.\u0000Results: There was a significant difference in mean triglyceride levels between groups K (-) and group K (+). This indicates that the induction of alloxan increases blood triglyceride levels. There were significant differences in the mean triglyceride levels between the K (+) and K (P) groups because tomato juice contained lycopene which could reduce triglyceride synthesis.\u0000Conclusions: Tomato juice (solanum lycopersicum) reduced wistar strain male Rattus novergicus triglyceride levels induced by alloxan.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"5 1","pages":"20-25"},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85097833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic Review: Comparison of triple drug therapy versus double drug therapy for Lymphatic Filariasis","authors":"I. Yana","doi":"10.33086/MHSJ.V5I1.1878","DOIUrl":"https://doi.org/10.33086/MHSJ.V5I1.1878","url":null,"abstract":"Background: Lymphatic filariasis is a parasitic infection caused by nematodes such as filaria Wuchereria bancrofti, Brugia malayi, and Brugia timori. These parasites can be transmitted through mosquito bites such as several species of mosquitoes, particularly Anopheles, Aedes, Culex, and Mansonia with geographical variations in the dominant vector identity. The main strategy used consists of community-wide mass drug administration (MDA) for the entire population at risk to stop disease transmission and prevent infectious morbidity. WHO recommends the use of annual medication in combination with the triple drug ivermectin therapy.\u0000Objective: To compare DEC and albendazole (IDA) versus the two drugs albendazole and diethycarbamazine or albendazole and ivermectin therapy.\u0000Methods: The literature search was carried out independently by the researcher using the Sciencedirect, Pubmed, and Cochrane online databases without limiting the type of study or the year of publication. The keywords used in this study were combined with the Boolean operator, namely \"AND\" namely ((((Lymphatic filariasis) AND (albendazole)) AND (diethylcarbamazine)) AND (ivermectin)) AND (compare).\u0000Results: Where triple drug therapy was significantly better in reducing and clearing microfilariae and worm nests in patients with lymphatic filariasis compared to two drug therapy alone. However, side effects occur more frequently in the combination of three therapies. The average side effects were low, such as headaches, joint pain, fatigue, and nausea.\u0000Conclusion: although it has relatively low side effects that occur in three drug combinations rather than two drug combination therapy, triple therapy combination therapy is more effective than two drug therapy in treating lymphatic filariasis disease.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"136 1","pages":"34-45"},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76389184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre Clinic Grade and Clinic Periods Effect on Progress Test of UNISMA Medical Profession Students","authors":"Ariani Ratri Dewi","doi":"10.33086/MHSJ.V5I1.1880","DOIUrl":"https://doi.org/10.33086/MHSJ.V5I1.1880","url":null,"abstract":"Introduction: Pre clinic grade point is often seen as predictor of good performance in professional education whose short term goal is to pass national examination which command progress test to evaluate the preparation.\u0000Purpose: To know the effect of pre clinic grade point and clinical study periods in progress test result of medical profession students.\u0000Methods: 135 students of medical profession programme completed computer based progress test of 200 national standardized questions in 200 minutes using siPENA software. Progress test result then analysed based on how long they have been studied and their pre clinic grade point using ANOVA – Tukey HSD and Pearson correlation in SPSS for Windows ver 19\u0000Results: Although students with pre clinic grade 2,50-2,74 have lower progress test result, but it’s not statistically significant (p>0,05). The same happen in clinic study periods with the longer the students in their clinical rotation, the better their result (p>0,05). The trends which showing better result in higher pre clinic grade point and time they spend in clinical rotation agrees with previous studies.\u0000Conclusion: Pre clinic grade point and clinic study periods has little to no effect on progress test result of medical profession students in UNISMA.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"36 1","pages":"14-19"},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88556472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Labor-Induced Pregnancy Cases In Dr Soetomo General Hospital: A Descriptive Study","authors":"Alfin Firasy","doi":"10.33086/MHSJ.V5I1.1673","DOIUrl":"https://doi.org/10.33086/MHSJ.V5I1.1673","url":null,"abstract":"Background: Labor induction is a procedure to stimulate uterine contractions during pregnancy before labor begins on its own to achieve a vaginal birth with medical or mechanical intervention to start the labor. This procedure aims to stimulate more extensive contraction in the uterus. The labor induction can reduce the caesarean rate. Prostaglandin E2 (PGE2) and misoprostol are the commonest medicine used to ripen the cervix in the Dr. Soetomo Hospital.\u0000Objective: Our study aim to evaluate the success rate of induction of labor patient.\u0000Methods: This study was a descriptive study using the medical record in 2018 in the Dr. Soetomo General Hospital, Surabaya. A total of 183 patient’s medical record data who underwent induced labor were used in this study. Inclusion criteria were the women with indication to deliver and have no cephalo-pelvic disproportion. Women with contraindication labor induction were excluded. Data was described using table and narrative approach. \u0000Results: The most range of gestational age was 21-36 weeks (53.01%) followed by 37-42 weeks (42.07%). There were 68 patients (37,1%) primigravida and 115 patients (62,8%) were multipara. The major induced labor was conducted with misoprostol (78.6%), and the most pelvic scores were 2 (58.46%) before underwent induced labor. Vertex delivery was the preferred mode of delivery after the induction of labor with 89 patients (48,62%). The labor induction failure followed with the caesarean operation were 27 patients (14,7%) and one patient (0,54%) with hysterotomy, most of them caused by failure to progress and fetal distress. There were 78 babies (43%) with the weight over 2500 g, 28 babies (31%) were over 2000 g, and the other was below 2000 g. A total of 84.71% with labor induction can be delivered vaginally, and It is a good number to reduce the rate of caesarean operations. \u0000Conclusion: This study concludes that misoprostol uses for the induction of labor than the other. Delivery abdominal is less percentage than the additional delivery finds that as a failure of induction of labor. The Labor induction success to delivered vaginally can reduce the rate of caesarean operation.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"23 1","pages":"7-13"},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90798046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Caulerpa Cylindracea Extract on Histopathology Depiction of Male Rattus Norvegicus Gaster Mucosa Induced by Indomethacin","authors":"Fitri Handajani, Adya Hidayatullah, Nita Pranitasari","doi":"10.33086/mhsj.v5i1.1671","DOIUrl":"https://doi.org/10.33086/mhsj.v5i1.1671","url":null,"abstract":"ABSTRACT\u0000Background: A lot of food can repair gastric mucosal damage. For example, sea grapes or the Caulerpa cylindracea with its flavonoid content. Anti-inflammatory and anti-ulcer effect can reduce gastric lesions due to ulcerogenic agents. Indomethacin is used to induce gastric ulcers in experimental animals. Based on this background, this study was conducted to analyze the effect of Caulerpa cylindracea extract, on the histopathological picture of gastric mucosal damage of Rattus norvegicus male rats.\u0000 \u0000Method: 32 male Rattus norvegicus rats were divided into 4 groups, (1) Group K(-), the untreated group, (2) Group K(+) induced by indomethacin 30mg/kgBB per head (3) Group P1 induced by indomethacin 30 mg/kgBB and Caulerpa cylindracea extract 1gr/100grBB per head, (4) Group P2, induced by indometacin 30mg/kgBB and 2gr/100grBB of Caulerpa cylindracea extract per head.\u0000 \u0000Result: There was a significant difference (p = 0.001) between the degree of gastric mucosal damage in group K(+) given only indomethacin and group P1 given Indomethacin and 1gr/100grBB Caulerpa cylindracea extract. There was a significant difference (p = 0.001) between group K(+) and group P2 that given Indomethacin and 2g/100grBB Caulerpa cylindracea extract. There was a significant difference (p = 0.004) between group P1 and group P2. Data revealed on group K(-) without any treatment did not obtain significant results (p = 0.060) with group P2. \u0000 \u0000Conclusion: Giving Caulerpa cylindracea extract with 1 gr/100grBB dose and 2gr/100grBB dose can repair mucosal damage in Rattus norvegicus male rats induced by indomethacin. \u0000 ","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73501212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}