Minimally Invasive Therapy & Allied Technologies最新文献

{"title":"Clinical efficacy of end-to-end anastomosis followed by mucosal folding and burying in minimally invasive esophageal cancer surgery.","authors":"Xianchao Chen, Yun Huang","doi":"10.1080/13645706.2025.2472724","DOIUrl":"https://doi.org/10.1080/13645706.2025.2472724","url":null,"abstract":"<p><strong>Background: </strong>Esophageal cancer is a common malignancy in China, with anastomotic fistula being a major postoperative complication. This study compares the clinical outcomes of end-to-end anastomosis and end-to-end anastomosis with mucosal folding and burying in minimally invasive esophageal cancer surgery.</p><p><strong>Methods: </strong>From October 2020 to March 2023, patients with esophageal cancer who underwent laparoscopic three-incision cervical anastomosis at the Fourth People's Hospital of Zigong City, were radomly assigned to receive either end-to-end anastomosis or end-to-end anastomosis followed by mucosal folding and burying. Clinical indicators, including hospitalization time, operation time, intraoperative blood loss, anastomotic fistula, and anastomotic stenosis, were compared between the two groups.</p><p><strong>Results: </strong>A total of 107 patients werencluded, with 56 in the end-to-end anastomosis with mucosal folding and burying technique group. There were no statistically significant differences between the two groups in operation time, intraoperative blood loss, anastomotic fistula rate, and anastomotic stenosis. However, for patients who received preoperative chemoradiotherapy or chemotherapy combined with immunotherapy, the incidence of anastomotic fistula was significantly lower in the group with end-to-end anastomosis with mucosal folding and burying.</p><p><strong>Conclusions: </strong>End-to-end anastomosis followed by mucosal folding and burying helps reduce the occurrence of anastomotic fistula, especially in patients receiving neoadjuvant chemoradiotherapy.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"1-10"},"PeriodicalIF":1.7,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fluorescence-guided mesorectal nodes harvesting associated with local excision for early rectal cancer: technical notes.","authors":"Ilaria Benzoni, Martina Fricano, Jessica Borali, Martina Bonafede, Andrea Celotti, Antonio Tarasconi, Valerio Ranieri, Luigi Totaro, Luca Mattia Quarti, Arianna Dendena, Giulia Grizzi, Maria Bonomi, Roberto Grassia, Barbara Frittoli, Gian Luca Baiocchi","doi":"10.1080/13645706.2025.2473587","DOIUrl":"https://doi.org/10.1080/13645706.2025.2473587","url":null,"abstract":"<p><strong>Background: </strong>The spread of colorectal cancer screening has increased the percentage of patients with early-stage rectal cancer; at least 30% of patients are diagnosed with a clinical-stage cT1 or pT1 after endoscopic excision. In this subgroup of patients, the real advantage of total mesorectal excision (TME) over local excision (LE) is the ability to remove mesorectal nodes, which are metastatic in less than 20% of cases.</p><p><strong>Method: </strong>To solve the unmet need for accurate nodal staging in patients with cT0/cT1, cN0 rectal cancer, we designed a pilot study that associates LE with mesorectal fluorescence-guided nodal sampling. From November 2018 to November 2023, we enrolled a total of ten patients with T1N0M0 rectal cancer. After extensive staging and adequate information, patients underwent endoscopic indocyanine green (ICG) infiltration and transanal local excision associated with laparoscopic fluorescence-guided mesorectal nodal sampling.</p><p><strong>Results: </strong>After a median follow-up of 24 months (range 1-63 months), no case of local or nodal recurrence was observed. All patients were spared from ostomy and lower anterior resection syndrome.</p><p><strong>Conclusions: </strong>In selected cases of cT0-1cN0 rectal cancer, transanal local excision plus ICG lymph nodal sampling is a feasible surgical option that increases the rate of organ preservation. Further studies are needed to identify the patients most likely to benefit from this minimally invasive strategy.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"1-7"},"PeriodicalIF":1.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of current and emerging endoluminal robotic platforms using the IDEAL framework.","authors":"Diya Shah, Freweini Martha Tesfai, Matthew Boal, Alberto Arezzo, Nader Francis","doi":"10.1080/13645706.2025.2467805","DOIUrl":"https://doi.org/10.1080/13645706.2025.2467805","url":null,"abstract":"<p><strong>Background: </strong>Robotic-assisted endoluminal systems are rapidly evolving within the field of minimally invasive surgery. The IDEAL framework (Idea, Development, Exploration, Assessment, and Surveillance) can be used to evaluate novel technologies. This review provides a summary of current and emerging endoluminal systems using the IDEAL framework.</p><p><strong>Methods: </strong>A scoping review was conducted to include all existing and developing robotic-assisted endoluminal systems. Data was collected <i>via</i> virtual interviews, questionnaires, biomedical databases, company websites, and peer-reviewed articles. Key metrics were reported, enabling the assignment of each system to an IDEAL stage.</p><p><strong>Results: </strong>The review identified 17 distinct systems from 16 companies. Nine systems received regulatory approval in their respective countries. Our evaluation showed that two systems were at the pre-IDEAL Stage 0. Seven systems were in the Idea stage (Stage 1), six systems were in the Development stage (Stage 2) and two systems completed Stage 3. No system underwent long-term study evaluation (Stage 4).</p><p><strong>Conclusions: </strong>There is a gap in long-term clinical data of robotic-assisted endoluminal systems, indicated by the absence of systems at Stage 4. Collaborative efforts amongst the medical community, regulatory bodies, and industry specialists are vital to ensure the delivery of evidence-based medicine in the discipline of robotics.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"1-14"},"PeriodicalIF":1.7,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A meta-analysis: laparoscopic versus open liver resection for large hepatocellular carcinoma.","authors":"Zha Peng, Zhuang-Rong Zhu, Cheng-Yi He, Hai Huang","doi":"10.1080/13645706.2024.2334762","DOIUrl":"10.1080/13645706.2024.2334762","url":null,"abstract":"<p><strong>Background: </strong>The indication of laparoscopic liver resection (LLR) for treating large hepatocellular carcinoma (HCC) is controversial. In this study, we compared the short-term and long-term outcomes of LLR and open liver resection (OLR) for large HCC.</p><p><strong>Material and methods: </strong>We searched eligible articles about LLR versus OLR for large HCC in PubMed, Cochrane Library, and EMBASE and performed a meta-analysis.</p><p><strong>Results: </strong>Eight publications involving 1,338 patients were included. Among them, 495 underwent LLR and 843 underwent OLR. The operation time was longer in the LLR group (MD: 22.23, 95% CI: 4.14-40.33, <i>p</i> = 0.02). but the postoperative hospital stay time was significantly shorter (MD : -4.88, CI: -5.55 to -4.23, <i>p</i> < 0.00001), and the incidence of total postoperative complications and major complications were significantly fewer (OR: 0.49, 95% CI:0.37-0.66, <i>p</i> < 0.00001; OR: 0.54, 95% CI:0.36 - 0.82, <i>p</i> = 0.003, respectively). Patients in the laparoscopic group had no significant difference in intraoperative blood loss, intraoperative transfusion rate, resection margin size, R0 resection rate, three-year overall survival (OS) and three-year disease-free survival (DFS).</p><p><strong>Conclusion: </strong>LLR for large HCC is safe and feasible. This surgical strategy will not affect the long-term outcomes of patients.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"24-34"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140864536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Camera sheath with transformable head for minimally invasive surgical instruments.","authors":"Seongil Kwon, Veysi Adin, Chulmin Park, Hanyong Chun, Keri Kim, Chunwoo Kim","doi":"10.1080/13645706.2024.2335540","DOIUrl":"10.1080/13645706.2024.2335540","url":null,"abstract":"<p><strong>Introduction: </strong>This paper presents a camera sheath that can be assembled to various minimally invasive surgical instruments and provide the localized view of the instrument tip.</p><p><strong>Material and methods: </strong>The advanced transformable head structure (ATHS) that overcomes the trade-off between the camera resolution and the instrument size is designed for the sheath. Design solutions to maintain the alignment between the camera's line of sight and the instrument tip direction during the transformation of the ATHS are derived and applied to the prototype of the sheath.</p><p><strong>Results: </strong>The design solution ensured proper alignment between the line of sight and the tip direction. The prototype was used with the curved micro-debrider blades in simulated functional endoscopic sinus surgery (FESS). Deep regions of the sinus that were not observable with the conventional endoscopes was accessed and observed using the prototype.</p><p><strong>Conclusions: </strong>The presented camera sheath allows the delivery of the instrument and camera to the surgical site with minimal increase in port size. It may be applied to various surgeries to reduce invasiveness and provide additional visual information to the surgeons.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"44-52"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lateral versus anterior approach for bladder neck dissection during robot-assisted radical prostatectomy: a pair-matched analysis to evaluate urinary continence and surgical margins.","authors":"Marco Oderda, Alessandro Marquis, Alberto Sasia, Giorgio Calleris, Alessandro Dematteis, Daniele D'Agate, Marco Falcone, Federico Lavagno, Giancarlo Marra, Gabriele Montefusco, Paolo Gontero","doi":"10.1080/13645706.2024.2369096","DOIUrl":"10.1080/13645706.2024.2369096","url":null,"abstract":"<p><strong>Introduction: </strong>The preservation of the bladder neck during robot-assisted radical prostatectomy (RARP) could improve urinary continence recovery and limit the risk of positive surgical margins (PSMs). We refined our lateral approach to the bladder neck technique and compared its outcomes with those of the standard anterior approach.</p><p><strong>Material and methods: </strong>From a retrospective analysis of 599 consecutive RARPs, 171 patients treated with the lateral and 171 patients treated with the anterior approach were pair-matched 1:1 on the basis of age, grade, and pathological stage. We described our surgical technique and compared the two approaches in terms of basal PSMs, recovery of urinary continence, and complications.</p><p><strong>Results: </strong>As compared to the anterior approach, the lateral approach had shorter operative times and comparable rates of basal PSMs and postoperative complications. The rates of urinary continence after one, three, and 12 months were comparable between the two groups and were generally higher in localized disease. At regression analysis, predictors of urinary incontinence were only age, pathological stage T3b, ISUP grade 5 and nerve-sparing surgery.</p><p><strong>Conclusions: </strong>The lateral approach leads to an anatomical dissection of the bladder neck without increasing the risk of PSMs. However, no significant benefits in terms of continence recovery were demonstrated over the standard anterior approach.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"8-14"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141446495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is cryoablation a valid option for renal cell carcinomas in direct contact with critical organs?","authors":"Shoma Nagata, Yusuke Matsui, Koji Tomita, Mayu Uka, Takahiro Kawabata, Noriyuki Umakoshi, Kazuaki Munetomo, Maria Kawada, Toshihiro Iguchi, Takao Hiraki","doi":"10.1080/13645706.2024.2354332","DOIUrl":"10.1080/13645706.2024.2354332","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess the outcomes of percutaneous cryoablation (PCA) for renal cell carcinomas (RCCs) contacting critical organs without intervening fat tissue.</p><p><strong>Material and methods: </strong>Twenty-three patients with 24 RCCs (mean size, 28.8 mm) contacting critical organs on preprocedural images were included. The organ displacement techniques, technical success, efficacy, and adverse events per Clavien-Dindo classification were retrospectively reviewed.</p><p><strong>Results: </strong>The organs contacting the RCCs included the colon (<i>n</i> = 16), pancreas (<i>n</i> = 3), duodenum (<i>n</i> = 3), small intestine (<i>n</i> = 1), and stomach (<i>n</i> = 1). In all procedures, hydrodissection was conducted, and probe traction was additionally utilized in one to displace organs. Two procedures were terminated with an insufficient ice-ball margin (<6 mm) due to recurring proximity of the colon or thermal sink effect by renal hilar vessels, yielding a technical success rate of 91.6% (22/24). No severe adverse events were noted. All patients were alive without any metastases during a median follow-up of 34.4 months. The primary and secondary technical efficacy rates were 91.6% (22/24) and 95.8% (23/24) of tumors, respectively.</p><p><strong>Conclusion: </strong>PCA can be a valid option for RCCs contacting critical organs with a good safety profile and sufficient technical efficacy.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"15-23"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140958050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic versus laparoscopic surgery for colorectal cancer in older patients: a systematic review and meta-analysis.","authors":"Xinyu Wang, Rui Ma, Tiewei Hou, Hao Xu, Cheng Zhang, Chun Ye","doi":"10.1080/13645706.2024.2359705","DOIUrl":"10.1080/13645706.2024.2359705","url":null,"abstract":"<p><strong>Objective: </strong>Robotic surgery is being increasingly used for colorectal cancer surgery. However, its utility versus laparoscopic surgery in older patients is unclear. We systematically examined evidence to assess the differences in short-term outcomes of robotic versus laparoscopic surgery for colorectal cancer in older patients.</p><p><strong>Material and methods: </strong>Comparative studies published on PubMed, Web of Science, Embase, and CENTRAL databases were searched up to August 30th, 2023.</p><p><strong>Results: </strong>Seven studies totaling 14,043 patients were included. Meta-analysis showed no difference in the operation time between the robotic and laparoscopic groups. Meta-analysis of ClavienDindo complications showed no difference between the robotic and laparoscopic groups for grades I and II or grades III and IV complications. Similarly, conversion to open surgery, reoperation rates and length of hospital stay were not significantly different between the two groups. Readmission rates and mortality rates were significantly lower with robotic surgery.</p><p><strong>Conclusion: </strong>This first meta-analysis comparing outcomes of robotic and laparoscopic surgery in older colorectal cancer patients shows that both approaches result in no difference in operating time, complication rates, conversion to open surgery, reoperation rates, and LOS. Scarce data shows that mortality and readmission rates may be lower with robotic surgery.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"35-43"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141179982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Partial splenic embolization with embosphere microspheres (700-900 µm) for the treatment of hypersplenism: comparison of selective superior splenic artery embolization and inferior splenic artery embolization.","authors":"Chao Ma, Yan Wang, Heng Zhang, Feng Duan, Mao-Qiang Wang","doi":"10.1080/13645706.2024.2339917","DOIUrl":"10.1080/13645706.2024.2339917","url":null,"abstract":"<p><strong>Objective: </strong>To compare clinical outcomes of superior versus inferior splenic artery embolization in partial splenic embolization (PSE) and identify predictors of major complications.</p><p><strong>Material and methods: </strong>This retrospective case-control study included 73 patients who underwent PSE between May 2005 and April 2021. They were divided into two groups: the superior and middle splenic artery embolization group (Group A, <i>n</i> = 37) and the inferior and middle splenic artery embolization group (Group B, <i>n</i> = 36). Outcome differences and major complications between the groups were assessed. Logistic regression was used to analyze potential predictors of major complications, and the optimal cutoff value for splenic embolization rates was determined using the Youden index.</p><p><strong>Results: </strong>There were no significant differences in laboratory and radiological outcomes between the two groups. Group A had a significantly lower incidence of major complications than Group B (<i>p</i> = 0.049), a lower Visual Analog Scale (VAS) score for pain (<i>p</i> = 0.036), and a shorter hospital stay (<i>p</i> = 0.022). Independent risk factors for major complications included inferior and middle splenic artery embolization (odds ratio [OR] = 3.672; 95% confidence interval [CI] = 1.028-13.120; <i>p</i> = 0.045) and a higher spleen embolization rate (OR = 1.108; 95% CI = 1.003-1.224; <i>p</i> = 0.044). The optimal cutoff for spleen embolization rate to predict major complications was 59.93% (sensitivity 77.8%, specificity 63.6%).</p><p><strong>Conclusion: </strong>Using 500-700 µm microspheres for PSE, targeting the middle and superior splenic artery yields similar effects to targeting the middle and inferior artery, but results in lower rates of major complications and shorter hospital stays. To effectively minimize the risk of major complications, the embolization rate should be kept below 59.93%, regardless of the target vessel.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"61-70"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140874702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"4DryField vs. hyalobarrier gel for preventing the recurrence of intrauterine adhesions - a pilot study.","authors":"Zdenka Lisa, Adela Richtarova, Kristyna Hlinecka, Barbora Boudova, David Kuzel, Michael Fanta, Michal Mara","doi":"10.1080/13645706.2024.2351829","DOIUrl":"10.1080/13645706.2024.2351829","url":null,"abstract":"<p><strong>Introduction: </strong>This was a single-center pilot study that sought to describe an innovative use of 4DryField® PH (premix) for preventing the recurrence of intrauterine adhesions (IUAs) after hysteroscopic adhesiolysis in patients with Asherman's syndrome (AS).</p><p><strong>Material and methods: </strong>Twenty-three patients with AS were enrolled and 20 were randomized (1:1 ratio) to intrauterine application of 4DryField® PH (<i>n</i> = 10) or Hyalobarrier^® gel (<i>n</i> = 10) in a single-blind manner. We evaluated IUAs (American Fertility Society [AFS] score) during initial hysteroscopy and second-look hysteroscopy one month later. Patients completed a follow-up symptoms questionnaire three and reproductive outcomes questionnaire six months later.</p><p><strong>Results: </strong>The demographic and clinical characteristics, as well as severity of IUAs, were comparable in both groups. The mean initial AFS score was 9 and 8.5 in the 4DryField^® PH and Hyalobarrier^® gel groups, respectively (<i>p</i> = .476). There were no between-group differences in AFS progress (5.9 vs. 5.6, <i>p</i> = .675), need for secondary adhesiolysis (7 vs. 7 patients, <i>p</i> = 1), and the follow-up outcomes.</p><p><strong>Conclusion: </strong>4DryField^® PH could be a promising antiadhesive agent for preventing the recurrence of IUAs, showing similar effectiveness and safety to Hyalobarrier^® gel. Our findings warrant prospective validation in a larger clinical trial.</p><p><strong>Clinical trial registry number: </strong>ISRCTN15630617.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"71-77"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141076282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}