Minimally Invasive Therapy & Allied Technologies最新文献

{"title":"A new method for placental volume measurements using tracked 2D ultrasound and automatic image segmentation.","authors":"Karianne Sagberg, Torgrim Lie, Helene F Peterson, Vigdis Hillestad, Anne Eskild, Lars Eirik Bø","doi":"10.1080/13645706.2025.2449699","DOIUrl":"https://doi.org/10.1080/13645706.2025.2449699","url":null,"abstract":"<p><strong>Background: </strong>Placental volume measurements can potentially identify high-risk pregnancies. We aimed to develop and validate a new method for placental volume measurements using tracked 2D ultrasound and automatic image segmentation.</p><p><strong>Methods: </strong>We included 43 pregnancies at gestational week 27 and acquired placental images using a 2D ultrasound probe with position tracking, and trained a convolutional neural network (CNN) for automatic image segmentation. The automatically segmented 2D images were combined with tracking data to calculate placental volume. For 15 of the included pregnancies, placental volume was also estimated based on MRI examinations, 3D ultrasound and manually segmented 2D ultrasound images. The ultrasound methods were compared to MRI (gold standard).</p><p><strong>Results: </strong>The CNN demonstrated good performance in automatic image segmentation (F1-score 0.84). The correlation with MRI-based placental volume was similar for tracked 2D ultrasound using automatically segmented images (absolute agreement intraclass correlation coefficient [ICC] 0.58, 95% CI 0.13-0.84) and manually segmented images (ICC 0.59, 95% CI 0.13-0.84). The 3D ultrasound method showed lower ICC (0.35, 95% CI -0.11 to 0.74) than the methods based on tracked 2D ultrasound.</p><p><strong>Conclusions: </strong>Tracked 2D ultrasound with automatic image segmentation is a promising new method for placental volume measurements and has potential for further improvement.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"1-9"},"PeriodicalIF":1.7,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A meta-analysis: laparoscopic versus open liver resection for large hepatocellular carcinoma.","authors":"Zha Peng, Zhuang-Rong Zhu, Cheng-Yi He, Hai Huang","doi":"10.1080/13645706.2024.2334762","DOIUrl":"10.1080/13645706.2024.2334762","url":null,"abstract":"<p><strong>Background: </strong>The indication of laparoscopic liver resection (LLR) for treating large hepatocellular carcinoma (HCC) is controversial. In this study, we compared the short-term and long-term outcomes of LLR and open liver resection (OLR) for large HCC.</p><p><strong>Material and methods: </strong>We searched eligible articles about LLR versus OLR for large HCC in PubMed, Cochrane Library, and EMBASE and performed a meta-analysis.</p><p><strong>Results: </strong>Eight publications involving 1,338 patients were included. Among them, 495 underwent LLR and 843 underwent OLR. The operation time was longer in the LLR group (MD: 22.23, 95% CI: 4.14-40.33, <i>p</i> = 0.02). but the postoperative hospital stay time was significantly shorter (MD : -4.88, CI: -5.55 to -4.23, <i>p</i> < 0.00001), and the incidence of total postoperative complications and major complications were significantly fewer (OR: 0.49, 95% CI:0.37-0.66, <i>p</i> < 0.00001; OR: 0.54, 95% CI:0.36 - 0.82, <i>p</i> = 0.003, respectively). Patients in the laparoscopic group had no significant difference in intraoperative blood loss, intraoperative transfusion rate, resection margin size, R0 resection rate, three-year overall survival (OS) and three-year disease-free survival (DFS).</p><p><strong>Conclusion: </strong>LLR for large HCC is safe and feasible. This surgical strategy will not affect the long-term outcomes of patients.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"24-34"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140864536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Camera sheath with transformable head for minimally invasive surgical instruments.","authors":"Seongil Kwon, Veysi Adin, Chulmin Park, Hanyong Chun, Keri Kim, Chunwoo Kim","doi":"10.1080/13645706.2024.2335540","DOIUrl":"10.1080/13645706.2024.2335540","url":null,"abstract":"<p><strong>Introduction: </strong>This paper presents a camera sheath that can be assembled to various minimally invasive surgical instruments and provide the localized view of the instrument tip.</p><p><strong>Material and methods: </strong>The advanced transformable head structure (ATHS) that overcomes the trade-off between the camera resolution and the instrument size is designed for the sheath. Design solutions to maintain the alignment between the camera's line of sight and the instrument tip direction during the transformation of the ATHS are derived and applied to the prototype of the sheath.</p><p><strong>Results: </strong>The design solution ensured proper alignment between the line of sight and the tip direction. The prototype was used with the curved micro-debrider blades in simulated functional endoscopic sinus surgery (FESS). Deep regions of the sinus that were not observable with the conventional endoscopes was accessed and observed using the prototype.</p><p><strong>Conclusions: </strong>The presented camera sheath allows the delivery of the instrument and camera to the surgical site with minimal increase in port size. It may be applied to various surgeries to reduce invasiveness and provide additional visual information to the surgeons.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"44-52"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lateral versus anterior approach for bladder neck dissection during robot-assisted radical prostatectomy: a pair-matched analysis to evaluate urinary continence and surgical margins.","authors":"Marco Oderda, Alessandro Marquis, Alberto Sasia, Giorgio Calleris, Alessandro Dematteis, Daniele D'Agate, Marco Falcone, Federico Lavagno, Giancarlo Marra, Gabriele Montefusco, Paolo Gontero","doi":"10.1080/13645706.2024.2369096","DOIUrl":"10.1080/13645706.2024.2369096","url":null,"abstract":"<p><strong>Introduction: </strong>The preservation of the bladder neck during robot-assisted radical prostatectomy (RARP) could improve urinary continence recovery and limit the risk of positive surgical margins (PSMs). We refined our lateral approach to the bladder neck technique and compared its outcomes with those of the standard anterior approach.</p><p><strong>Material and methods: </strong>From a retrospective analysis of 599 consecutive RARPs, 171 patients treated with the lateral and 171 patients treated with the anterior approach were pair-matched 1:1 on the basis of age, grade, and pathological stage. We described our surgical technique and compared the two approaches in terms of basal PSMs, recovery of urinary continence, and complications.</p><p><strong>Results: </strong>As compared to the anterior approach, the lateral approach had shorter operative times and comparable rates of basal PSMs and postoperative complications. The rates of urinary continence after one, three, and 12 months were comparable between the two groups and were generally higher in localized disease. At regression analysis, predictors of urinary incontinence were only age, pathological stage T3b, ISUP grade 5 and nerve-sparing surgery.</p><p><strong>Conclusions: </strong>The lateral approach leads to an anatomical dissection of the bladder neck without increasing the risk of PSMs. However, no significant benefits in terms of continence recovery were demonstrated over the standard anterior approach.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"8-14"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141446495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic versus laparoscopic surgery for colorectal cancer in older patients: a systematic review and meta-analysis.","authors":"Xinyu Wang, Rui Ma, Tiewei Hou, Hao Xu, Cheng Zhang, Chun Ye","doi":"10.1080/13645706.2024.2359705","DOIUrl":"10.1080/13645706.2024.2359705","url":null,"abstract":"<p><strong>Objective: </strong>Robotic surgery is being increasingly used for colorectal cancer surgery. However, its utility versus laparoscopic surgery in older patients is unclear. We systematically examined evidence to assess the differences in short-term outcomes of robotic versus laparoscopic surgery for colorectal cancer in older patients.</p><p><strong>Material and methods: </strong>Comparative studies published on PubMed, Web of Science, Embase, and CENTRAL databases were searched up to August 30th, 2023.</p><p><strong>Results: </strong>Seven studies totaling 14,043 patients were included. Meta-analysis showed no difference in the operation time between the robotic and laparoscopic groups. Meta-analysis of ClavienDindo complications showed no difference between the robotic and laparoscopic groups for grades I and II or grades III and IV complications. Similarly, conversion to open surgery, reoperation rates and length of hospital stay were not significantly different between the two groups. Readmission rates and mortality rates were significantly lower with robotic surgery.</p><p><strong>Conclusion: </strong>This first meta-analysis comparing outcomes of robotic and laparoscopic surgery in older colorectal cancer patients shows that both approaches result in no difference in operating time, complication rates, conversion to open surgery, reoperation rates, and LOS. Scarce data shows that mortality and readmission rates may be lower with robotic surgery.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"35-43"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141179982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is cryoablation a valid option for renal cell carcinomas in direct contact with critical organs?","authors":"Shoma Nagata, Yusuke Matsui, Koji Tomita, Mayu Uka, Takahiro Kawabata, Noriyuki Umakoshi, Kazuaki Munetomo, Maria Kawada, Toshihiro Iguchi, Takao Hiraki","doi":"10.1080/13645706.2024.2354332","DOIUrl":"10.1080/13645706.2024.2354332","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess the outcomes of percutaneous cryoablation (PCA) for renal cell carcinomas (RCCs) contacting critical organs without intervening fat tissue.</p><p><strong>Material and methods: </strong>Twenty-three patients with 24 RCCs (mean size, 28.8 mm) contacting critical organs on preprocedural images were included. The organ displacement techniques, technical success, efficacy, and adverse events per Clavien-Dindo classification were retrospectively reviewed.</p><p><strong>Results: </strong>The organs contacting the RCCs included the colon (<i>n</i> = 16), pancreas (<i>n</i> = 3), duodenum (<i>n</i> = 3), small intestine (<i>n</i> = 1), and stomach (<i>n</i> = 1). In all procedures, hydrodissection was conducted, and probe traction was additionally utilized in one to displace organs. Two procedures were terminated with an insufficient ice-ball margin (<6 mm) due to recurring proximity of the colon or thermal sink effect by renal hilar vessels, yielding a technical success rate of 91.6% (22/24). No severe adverse events were noted. All patients were alive without any metastases during a median follow-up of 34.4 months. The primary and secondary technical efficacy rates were 91.6% (22/24) and 95.8% (23/24) of tumors, respectively.</p><p><strong>Conclusion: </strong>PCA can be a valid option for RCCs contacting critical organs with a good safety profile and sufficient technical efficacy.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"15-23"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140958050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Partial splenic embolization with embosphere microspheres (700-900 µm) for the treatment of hypersplenism: comparison of selective superior splenic artery embolization and inferior splenic artery embolization.","authors":"Chao Ma, Yan Wang, Heng Zhang, Feng Duan, Mao-Qiang Wang","doi":"10.1080/13645706.2024.2339917","DOIUrl":"10.1080/13645706.2024.2339917","url":null,"abstract":"<p><strong>Objective: </strong>To compare clinical outcomes of superior versus inferior splenic artery embolization in partial splenic embolization (PSE) and identify predictors of major complications.</p><p><strong>Material and methods: </strong>This retrospective case-control study included 73 patients who underwent PSE between May 2005 and April 2021. They were divided into two groups: the superior and middle splenic artery embolization group (Group A, <i>n</i> = 37) and the inferior and middle splenic artery embolization group (Group B, <i>n</i> = 36). Outcome differences and major complications between the groups were assessed. Logistic regression was used to analyze potential predictors of major complications, and the optimal cutoff value for splenic embolization rates was determined using the Youden index.</p><p><strong>Results: </strong>There were no significant differences in laboratory and radiological outcomes between the two groups. Group A had a significantly lower incidence of major complications than Group B (<i>p</i> = 0.049), a lower Visual Analog Scale (VAS) score for pain (<i>p</i> = 0.036), and a shorter hospital stay (<i>p</i> = 0.022). Independent risk factors for major complications included inferior and middle splenic artery embolization (odds ratio [OR] = 3.672; 95% confidence interval [CI] = 1.028-13.120; <i>p</i> = 0.045) and a higher spleen embolization rate (OR = 1.108; 95% CI = 1.003-1.224; <i>p</i> = 0.044). The optimal cutoff for spleen embolization rate to predict major complications was 59.93% (sensitivity 77.8%, specificity 63.6%).</p><p><strong>Conclusion: </strong>Using 500-700 µm microspheres for PSE, targeting the middle and superior splenic artery yields similar effects to targeting the middle and inferior artery, but results in lower rates of major complications and shorter hospital stays. To effectively minimize the risk of major complications, the embolization rate should be kept below 59.93%, regardless of the target vessel.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"61-70"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140874702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"4DryField vs. hyalobarrier gel for preventing the recurrence of intrauterine adhesions - a pilot study.","authors":"Zdenka Lisa, Adela Richtarova, Kristyna Hlinecka, Barbora Boudova, David Kuzel, Michael Fanta, Michal Mara","doi":"10.1080/13645706.2024.2351829","DOIUrl":"10.1080/13645706.2024.2351829","url":null,"abstract":"<p><strong>Introduction: </strong>This was a single-center pilot study that sought to describe an innovative use of 4DryField® PH (premix) for preventing the recurrence of intrauterine adhesions (IUAs) after hysteroscopic adhesiolysis in patients with Asherman's syndrome (AS).</p><p><strong>Material and methods: </strong>Twenty-three patients with AS were enrolled and 20 were randomized (1:1 ratio) to intrauterine application of 4DryField® PH (<i>n</i> = 10) or Hyalobarrier^® gel (<i>n</i> = 10) in a single-blind manner. We evaluated IUAs (American Fertility Society [AFS] score) during initial hysteroscopy and second-look hysteroscopy one month later. Patients completed a follow-up symptoms questionnaire three and reproductive outcomes questionnaire six months later.</p><p><strong>Results: </strong>The demographic and clinical characteristics, as well as severity of IUAs, were comparable in both groups. The mean initial AFS score was 9 and 8.5 in the 4DryField^® PH and Hyalobarrier^® gel groups, respectively (<i>p</i> = .476). There were no between-group differences in AFS progress (5.9 vs. 5.6, <i>p</i> = .675), need for secondary adhesiolysis (7 vs. 7 patients, <i>p</i> = 1), and the follow-up outcomes.</p><p><strong>Conclusion: </strong>4DryField^® PH could be a promising antiadhesive agent for preventing the recurrence of IUAs, showing similar effectiveness and safety to Hyalobarrier^® gel. Our findings warrant prospective validation in a larger clinical trial.</p><p><strong>Clinical trial registry number: </strong>ISRCTN15630617.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"71-77"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141076282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The vaginal route for minimally invasive surgery: a practical guide for general surgeons.","authors":"Matteo Pavone, Lise Lecointre, Barbara Seeliger, Riccardo Oliva, Cherif Akladios, Denis Querleu, Giovanni Scambia, Jacques Marescaux, Antonello Forgione","doi":"10.1080/13645706.2024.2359707","DOIUrl":"10.1080/13645706.2024.2359707","url":null,"abstract":"<p><strong>Introduction: </strong>Vaginal approaches have become routine in the field of gynecologic surgery, whereas in general surgery vaginal wall transection is an infrequent practice typically reserved for extensive tumor resections. Approximately two decades ago, natural orifice transluminal endoscopic surgery (NOTES) revolutionized conventional boundaries by accessing the peritoneal cavity transorally, transrectally, or transvaginally, enabling general surgery without visible scars. Although transvaginal approaches have been successfully used for various abdominal procedures by general surgeons, a gap remains in comprehensive training to fully exploit the potential of this route.</p><p><strong>Material and methods: </strong>PubMed, Google Scholar, and Scopus databases were searched to retrieve relevant articles illustrating how general surgeons can adeptly manage vaginal approaches.</p><p><strong>Results: </strong>The article presents a practical framework for general surgeons to execute a complete vaginal approach, addressing the management of vaginal specimen extraction and vaginal cuff closure, even in the absence of an experienced gynecologist.</p><p><strong>Conclusion: </strong>The evolution of abdominal surgery is moving towards less invasive techniques, emphasizing the importance of understanding the nuances and challenges associated with the vaginal route. This approach is linked to minimal oncological, sexual, and infective complications, and to the absence of pregnancy-related complications. Such knowledge becomes increasingly crucial, particularly with the renewed demand for transvaginal access in robot-assisted NOTES procedures.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"78-87"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141293555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3-Fr steerable microcatheter system via the upper limb artery in RADPLAT for right maxillary cancer.","authors":"Masao Takahashi, Ken Nakazawa, Yoko Usami, Yuki Natsuyama, Yuichi Tsukamoto, Jun Suzuki, Shiho Asami, Hitoshi Inoue, Satoko Matsumura, Mitsuhiko Nakahira, Tetsu Saito, Shingo Kato, Yoshitaka Okada, Hiroyuki Tajima, Eito Kozawa, Yasutaka Baba","doi":"10.1080/13645706.2024.2359718","DOIUrl":"10.1080/13645706.2024.2359718","url":null,"abstract":"<p><strong>Background: </strong>To evaluate the efficacy of a catheter system using a 3-Fr sheath with a steerable microcatheter through right upper limb artery access for superselective intra-arterial cisplatin infusion and concomitant radiotherapy (RADPLAT) to treat right maxillary sinus squamous cell carcinoma (MS-SCC).</p><p><strong>Material and methods: </strong>We retrospectively studied 46 sessions in eight patients treated between November 2020 and February 2023 using the catheter system briefly described below. A 3-Fr sheath was inserted into the distal radial, conventional radial, or brachial arteries. A coaxial catheter system with a 2.9-Fr steerable microcatheter and a 1.9-Fr microcatheter was advanced into the brachiocephalic artery. The right common carotid artery was selected by bending the tip of the steerable microcatheter. Coil embolization and intra-arterial cisplatin infusion after selecting each external carotid artery branch were achieved using this catheter system.</p><p><strong>Results: </strong>Cisplatin infusion and coil embolization were successful in all sessions. Arterial occlusion at the sheath insertion sites was found in 29.4% (5/17) of the distal radial arteries and 33.3% (3/9) of the conventional radial arteries. No other major complications were observed during the procedure.</p><p><strong>Conclusion: </strong>Using a 3-Fr catheter system with a steerable microcatheter through right upper limb artery access is a feasible method for RADPLAT in treating right MS-SCC.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"53-60"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141157151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}