{"title":"Advancing apical POP treatment: a comparative analysis of vNOTES lateral suspension and laparoscopic lateral suspension.","authors":"Gizem Berfin Uluutku Bulutlar, Eralp Bulutlar, Ayşe Betül Albayrak Denizli, Çetin Kılıççı","doi":"10.1080/13645706.2025.2532108","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Apical pelvic organ prolapse (POP) significantly impacts quality of life. The vaginal natural orifice transluminal endoscopic surgery lateral suspension (vNOTES LS) combines the benefits of vNOTES and mesh-based suspension. This study compares clinical outcomes of vNOTES LS and laparoscopic lateral suspension (LLS) in patients with ≥ Stage 3 apical POP.</p><p><strong>Methods: </strong>In this retrospective cohort study, 80 patients with ≥ Stage 3 apical and/or anterior wall defects underwent hysterectomy with vNOTES LS (<i>n</i> = 40) or LLS (<i>n</i> = 40) between January 2022 and January 2024. Perioperative parameters, postoperative outcomes, and POP-Q measurements (Ba and C) were analyzed.</p><p><strong>Results: </strong>Preoperative characteristics, including BMI and prolapse stage, were comparable. Postoperative POP-Q measurements (Ba and C) significantly improved in the vNOTES LS group at day 1, month 6, and year 1 (<i>p</i> < 0.05). Operative time and hematocrit changes were similar (<i>p</i> > 0.05). Hospital stay was shorter with vNOTES LS (1.05 ± 0.22 vs. 2.2 ± 0.75 days, <i>p</i> < 0.05), and fewer complications were noted. No urinary injury, mesh erosion, or recurrence occurred in the vNOTES LS group.</p><p><strong>Conclusions: </strong>vNOTES LS demonstrated comparable success to LLS with shorter hospital stays and fewer complications. Its minimally invasive nature highlights its potential as a promising alternative for selected patients.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":"34 5","pages":"416-423"},"PeriodicalIF":2.0000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Minimally Invasive Therapy & Allied Technologies","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/13645706.2025.2532108","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/26 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"SURGERY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Apical pelvic organ prolapse (POP) significantly impacts quality of life. The vaginal natural orifice transluminal endoscopic surgery lateral suspension (vNOTES LS) combines the benefits of vNOTES and mesh-based suspension. This study compares clinical outcomes of vNOTES LS and laparoscopic lateral suspension (LLS) in patients with ≥ Stage 3 apical POP.
Methods: In this retrospective cohort study, 80 patients with ≥ Stage 3 apical and/or anterior wall defects underwent hysterectomy with vNOTES LS (n = 40) or LLS (n = 40) between January 2022 and January 2024. Perioperative parameters, postoperative outcomes, and POP-Q measurements (Ba and C) were analyzed.
Results: Preoperative characteristics, including BMI and prolapse stage, were comparable. Postoperative POP-Q measurements (Ba and C) significantly improved in the vNOTES LS group at day 1, month 6, and year 1 (p < 0.05). Operative time and hematocrit changes were similar (p > 0.05). Hospital stay was shorter with vNOTES LS (1.05 ± 0.22 vs. 2.2 ± 0.75 days, p < 0.05), and fewer complications were noted. No urinary injury, mesh erosion, or recurrence occurred in the vNOTES LS group.
Conclusions: vNOTES LS demonstrated comparable success to LLS with shorter hospital stays and fewer complications. Its minimally invasive nature highlights its potential as a promising alternative for selected patients.
期刊介绍:
Minimally Invasive Therapy and Allied Technologies (MITAT) is an international forum for endoscopic surgeons, interventional radiologists and industrial instrument manufacturers. It is the official journal of the Society for Medical Innovation and Technology (SMIT) whose membership includes representatives from a broad spectrum of medical specialities, instrument manufacturing and research. The journal brings the latest developments and innovations in minimally invasive therapy to its readers. What makes Minimally Invasive Therapy and Allied Technologies unique is that we publish one or two special issues each year, which are devoted to a specific theme. Key topics covered by the journal include: interventional radiology, endoscopic surgery, imaging technology, manipulators and robotics for surgery and education and training for MIS.