Minimally Invasive Therapy & Allied Technologies最新文献

{"title":"Robotic versus laparoscopic surgery for colorectal cancer in older patients: a systematic review and meta-analysis.","authors":"Xinyu Wang, Rui Ma, Tiewei Hou, Hao Xu, Cheng Zhang, Chun Ye","doi":"10.1080/13645706.2024.2359705","DOIUrl":"10.1080/13645706.2024.2359705","url":null,"abstract":"<p><strong>Objective: </strong>Robotic surgery is being increasingly used for colorectal cancer surgery. However, its utility versus laparoscopic surgery in older patients is unclear. We systematically examined evidence to assess the differences in short-term outcomes of robotic versus laparoscopic surgery for colorectal cancer in older patients.</p><p><strong>Material and methods: </strong>Comparative studies published on PubMed, Web of Science, Embase, and CENTRAL databases were searched up to August 30th, 2023.</p><p><strong>Results: </strong>Seven studies totaling 14,043 patients were included. Meta-analysis showed no difference in the operation time between the robotic and laparoscopic groups. Meta-analysis of ClavienDindo complications showed no difference between the robotic and laparoscopic groups for grades I and II or grades III and IV complications. Similarly, conversion to open surgery, reoperation rates and length of hospital stay were not significantly different between the two groups. Readmission rates and mortality rates were significantly lower with robotic surgery.</p><p><strong>Conclusion: </strong>This first meta-analysis comparing outcomes of robotic and laparoscopic surgery in older colorectal cancer patients shows that both approaches result in no difference in operating time, complication rates, conversion to open surgery, reoperation rates, and LOS. Scarce data shows that mortality and readmission rates may be lower with robotic surgery.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"35-43"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141179982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is cryoablation a valid option for renal cell carcinomas in direct contact with critical organs?","authors":"Shoma Nagata, Yusuke Matsui, Koji Tomita, Mayu Uka, Takahiro Kawabata, Noriyuki Umakoshi, Kazuaki Munetomo, Maria Kawada, Toshihiro Iguchi, Takao Hiraki","doi":"10.1080/13645706.2024.2354332","DOIUrl":"10.1080/13645706.2024.2354332","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess the outcomes of percutaneous cryoablation (PCA) for renal cell carcinomas (RCCs) contacting critical organs without intervening fat tissue.</p><p><strong>Material and methods: </strong>Twenty-three patients with 24 RCCs (mean size, 28.8 mm) contacting critical organs on preprocedural images were included. The organ displacement techniques, technical success, efficacy, and adverse events per Clavien-Dindo classification were retrospectively reviewed.</p><p><strong>Results: </strong>The organs contacting the RCCs included the colon (<i>n</i> = 16), pancreas (<i>n</i> = 3), duodenum (<i>n</i> = 3), small intestine (<i>n</i> = 1), and stomach (<i>n</i> = 1). In all procedures, hydrodissection was conducted, and probe traction was additionally utilized in one to displace organs. Two procedures were terminated with an insufficient ice-ball margin (<6 mm) due to recurring proximity of the colon or thermal sink effect by renal hilar vessels, yielding a technical success rate of 91.6% (22/24). No severe adverse events were noted. All patients were alive without any metastases during a median follow-up of 34.4 months. The primary and secondary technical efficacy rates were 91.6% (22/24) and 95.8% (23/24) of tumors, respectively.</p><p><strong>Conclusion: </strong>PCA can be a valid option for RCCs contacting critical organs with a good safety profile and sufficient technical efficacy.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"15-23"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140958050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Partial splenic embolization with embosphere microspheres (700-900 µm) for the treatment of hypersplenism: comparison of selective superior splenic artery embolization and inferior splenic artery embolization.","authors":"Chao Ma, Yan Wang, Heng Zhang, Feng Duan, Mao-Qiang Wang","doi":"10.1080/13645706.2024.2339917","DOIUrl":"10.1080/13645706.2024.2339917","url":null,"abstract":"<p><strong>Objective: </strong>To compare clinical outcomes of superior versus inferior splenic artery embolization in partial splenic embolization (PSE) and identify predictors of major complications.</p><p><strong>Material and methods: </strong>This retrospective case-control study included 73 patients who underwent PSE between May 2005 and April 2021. They were divided into two groups: the superior and middle splenic artery embolization group (Group A, <i>n</i> = 37) and the inferior and middle splenic artery embolization group (Group B, <i>n</i> = 36). Outcome differences and major complications between the groups were assessed. Logistic regression was used to analyze potential predictors of major complications, and the optimal cutoff value for splenic embolization rates was determined using the Youden index.</p><p><strong>Results: </strong>There were no significant differences in laboratory and radiological outcomes between the two groups. Group A had a significantly lower incidence of major complications than Group B (<i>p</i> = 0.049), a lower Visual Analog Scale (VAS) score for pain (<i>p</i> = 0.036), and a shorter hospital stay (<i>p</i> = 0.022). Independent risk factors for major complications included inferior and middle splenic artery embolization (odds ratio [OR] = 3.672; 95% confidence interval [CI] = 1.028-13.120; <i>p</i> = 0.045) and a higher spleen embolization rate (OR = 1.108; 95% CI = 1.003-1.224; <i>p</i> = 0.044). The optimal cutoff for spleen embolization rate to predict major complications was 59.93% (sensitivity 77.8%, specificity 63.6%).</p><p><strong>Conclusion: </strong>Using 500-700 µm microspheres for PSE, targeting the middle and superior splenic artery yields similar effects to targeting the middle and inferior artery, but results in lower rates of major complications and shorter hospital stays. To effectively minimize the risk of major complications, the embolization rate should be kept below 59.93%, regardless of the target vessel.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"61-70"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140874702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"4DryField vs. hyalobarrier gel for preventing the recurrence of intrauterine adhesions - a pilot study.","authors":"Zdenka Lisa, Adela Richtarova, Kristyna Hlinecka, Barbora Boudova, David Kuzel, Michael Fanta, Michal Mara","doi":"10.1080/13645706.2024.2351829","DOIUrl":"10.1080/13645706.2024.2351829","url":null,"abstract":"<p><strong>Introduction: </strong>This was a single-center pilot study that sought to describe an innovative use of 4DryField® PH (premix) for preventing the recurrence of intrauterine adhesions (IUAs) after hysteroscopic adhesiolysis in patients with Asherman's syndrome (AS).</p><p><strong>Material and methods: </strong>Twenty-three patients with AS were enrolled and 20 were randomized (1:1 ratio) to intrauterine application of 4DryField® PH (<i>n</i> = 10) or Hyalobarrier^® gel (<i>n</i> = 10) in a single-blind manner. We evaluated IUAs (American Fertility Society [AFS] score) during initial hysteroscopy and second-look hysteroscopy one month later. Patients completed a follow-up symptoms questionnaire three and reproductive outcomes questionnaire six months later.</p><p><strong>Results: </strong>The demographic and clinical characteristics, as well as severity of IUAs, were comparable in both groups. The mean initial AFS score was 9 and 8.5 in the 4DryField^® PH and Hyalobarrier^® gel groups, respectively (<i>p</i> = .476). There were no between-group differences in AFS progress (5.9 vs. 5.6, <i>p</i> = .675), need for secondary adhesiolysis (7 vs. 7 patients, <i>p</i> = 1), and the follow-up outcomes.</p><p><strong>Conclusion: </strong>4DryField^® PH could be a promising antiadhesive agent for preventing the recurrence of IUAs, showing similar effectiveness and safety to Hyalobarrier^® gel. Our findings warrant prospective validation in a larger clinical trial.</p><p><strong>Clinical trial registry number: </strong>ISRCTN15630617.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"71-77"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141076282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The vaginal route for minimally invasive surgery: a practical guide for general surgeons.","authors":"Matteo Pavone, Lise Lecointre, Barbara Seeliger, Riccardo Oliva, Cherif Akladios, Denis Querleu, Giovanni Scambia, Jacques Marescaux, Antonello Forgione","doi":"10.1080/13645706.2024.2359707","DOIUrl":"10.1080/13645706.2024.2359707","url":null,"abstract":"<p><strong>Introduction: </strong>Vaginal approaches have become routine in the field of gynecologic surgery, whereas in general surgery vaginal wall transection is an infrequent practice typically reserved for extensive tumor resections. Approximately two decades ago, natural orifice transluminal endoscopic surgery (NOTES) revolutionized conventional boundaries by accessing the peritoneal cavity transorally, transrectally, or transvaginally, enabling general surgery without visible scars. Although transvaginal approaches have been successfully used for various abdominal procedures by general surgeons, a gap remains in comprehensive training to fully exploit the potential of this route.</p><p><strong>Material and methods: </strong>PubMed, Google Scholar, and Scopus databases were searched to retrieve relevant articles illustrating how general surgeons can adeptly manage vaginal approaches.</p><p><strong>Results: </strong>The article presents a practical framework for general surgeons to execute a complete vaginal approach, addressing the management of vaginal specimen extraction and vaginal cuff closure, even in the absence of an experienced gynecologist.</p><p><strong>Conclusion: </strong>The evolution of abdominal surgery is moving towards less invasive techniques, emphasizing the importance of understanding the nuances and challenges associated with the vaginal route. This approach is linked to minimal oncological, sexual, and infective complications, and to the absence of pregnancy-related complications. Such knowledge becomes increasingly crucial, particularly with the renewed demand for transvaginal access in robot-assisted NOTES procedures.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"78-87"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141293555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3-Fr steerable microcatheter system via the upper limb artery in RADPLAT for right maxillary cancer.","authors":"Masao Takahashi, Ken Nakazawa, Yoko Usami, Yuki Natsuyama, Yuichi Tsukamoto, Jun Suzuki, Shiho Asami, Hitoshi Inoue, Satoko Matsumura, Mitsuhiko Nakahira, Tetsu Saito, Shingo Kato, Yoshitaka Okada, Hiroyuki Tajima, Eito Kozawa, Yasutaka Baba","doi":"10.1080/13645706.2024.2359718","DOIUrl":"10.1080/13645706.2024.2359718","url":null,"abstract":"<p><strong>Background: </strong>To evaluate the efficacy of a catheter system using a 3-Fr sheath with a steerable microcatheter through right upper limb artery access for superselective intra-arterial cisplatin infusion and concomitant radiotherapy (RADPLAT) to treat right maxillary sinus squamous cell carcinoma (MS-SCC).</p><p><strong>Material and methods: </strong>We retrospectively studied 46 sessions in eight patients treated between November 2020 and February 2023 using the catheter system briefly described below. A 3-Fr sheath was inserted into the distal radial, conventional radial, or brachial arteries. A coaxial catheter system with a 2.9-Fr steerable microcatheter and a 1.9-Fr microcatheter was advanced into the brachiocephalic artery. The right common carotid artery was selected by bending the tip of the steerable microcatheter. Coil embolization and intra-arterial cisplatin infusion after selecting each external carotid artery branch were achieved using this catheter system.</p><p><strong>Results: </strong>Cisplatin infusion and coil embolization were successful in all sessions. Arterial occlusion at the sheath insertion sites was found in 29.4% (5/17) of the distal radial arteries and 33.3% (3/9) of the conventional radial arteries. No other major complications were observed during the procedure.</p><p><strong>Conclusion: </strong>Using a 3-Fr catheter system with a steerable microcatheter through right upper limb artery access is a feasible method for RADPLAT in treating right MS-SCC.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"53-60"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141157151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"10-year experience with single-site laparoscopic-assisted Soave operation for Hirschsprung disease.","authors":"Yun-Jin Wang, Yi-Fan Fang, Hua-Jun Cai, Liu Chen, Chao-Ming Zhou, Guo-Xian Guan","doi":"10.1080/13645706.2025.2454966","DOIUrl":"https://doi.org/10.1080/13645706.2025.2454966","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to investigate the clinical outcomes after a transumbilical single-site laparoscopic-assisted Soave operation (TSLSO) for Hirschsprung disease (HD) in children, with a 10-year follow‑up results assessment.</p><p><strong>Methods: </strong>We retrospectively analyzed the clinical data of 165 children with HD from January 2013 to January 2023. The operation method was a TSLSO. The operation time, intraoperative bleeding, postoperative abdominal drainage time, postoperative hospitalization time, and postoperative complications were analyzed.</p><p><strong>Results: </strong>All 165 cases were successfully completed using the TSLSO. The median operative time was 160 (120-210) minutes, and the median volume of bleeding was 9 mL (3-15 mL). The median length of the resected intestine was 25 cm (20-32 cm), and the median postoperative peritoneal drainage time was 4.2 days (3-6 days). Postoperative defecation function generally recovered well, there was no recurrence of constipation. There were three cases of anal stenosis, 12 cases of perianal dermatitis, two cases of adhesive intestinal obstruction, 14 cases of soiling, and 18 cases of enterocolitis.</p><p><strong>Conclusion: </strong>The TSLSO is a safe and feasible surgical method for the treatment of HD in children. It has the advantages of little bleeding, a good cosmetic effect, and fast postoperative recovery. However, it does require skilled laparoscopic technique by the surgeon.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"1-7"},"PeriodicalIF":1.7,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endovascular robotics: technical advances and future directions.","authors":"Matteo Pescio, Dennis Kundrat, Giulio Dagnino","doi":"10.1080/13645706.2025.2454237","DOIUrl":"https://doi.org/10.1080/13645706.2025.2454237","url":null,"abstract":"<p><p>Endovascular interventions excel in treating cardiovascular diseases in a minimally invasive manner, showing improved outcomes over open techniques. However, challenges related to precise navigation - still relying on 2D fluoroscopy - persist. This review examines the role of robotics, highlighting commercial and research platforms, while exploring emerging trends like MRI compatibility, enhanced navigation, and autonomy. MRI-compatible systems offer radiation-free 3D imaging. Human-robot interaction evolves with task-specific interfaces, while autonomy ranges from partial to full, aiding clinical operators. Challenges include complexity and cost, emphasizing compatibility and navigation advancements. Integrating MRI-compatible robots, refining human-robot interaction, and enhancing autonomy promise advancements in endovascular surgery, fueled by AI and innovative imaging.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"1-14"},"PeriodicalIF":1.7,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143008277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and efficacy of endoscopic resection for gastric gastrointestinal stromal tumors: a retrospective cohort study.","authors":"Xiaodan Zhao, Yadong Feng, Mingyue Li, Ye Zhu, Xiajiao Tang, Ruihua Shi","doi":"10.1080/13645706.2024.2449266","DOIUrl":"https://doi.org/10.1080/13645706.2024.2449266","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to verify the safety and efficacy of endoscopic resection (ER) for gastric gastrointestinal stromal tumors (GISTs).</p><p><strong>Methods: </strong>Among a consecutive series of resections for gastric GISTs performed in a single center, the outcomes of patients who had ER were compared to standard surgical resection (SR).</p><p><strong>Results: </strong>In the cohort, 329 consecutive primary localized gastric GISTs patients (<i>n</i>, ER/SR = 251/78) were enrolled. Patients receiving ER were revealed to have preferable post-treatment outcomes, prolonged overall survival (OS) and disease-free survival (DFS). Tumor diameter, the only independent risk factor for a complicated post-operative course, was utilized for propensity score matching (PSM). In the PSM cohort, patients receiving ER and SR with similar tumor size (4.0 [2.7-4.5] cm) shared similar aggressiveness in terms of stomach layers of tumor origination and invasion, and modified National Institutes of Health (mNIH) risk criteria. Shorter operative time, fewer economic costs, and shorter post-operative stay were still observed in the ER group (ER vs. SR: 80 [49-120] vs. 120 [98-160] minutes, <i>p</i> < 0.001; 44 [38-51] vs. 60 [49-84] thousand Renminbi [kRMB], <i>p</i> < 0.001; 7.0 [6.0-8.0] vs. 8.5 [6.0-12] days, <i>p</i> = 0.018, respectively). No significant difference in OS and DFS was demonstrated in the PSM cohort.</p><p><strong>Conclusions: </strong>ER is safe and effective, thus a feasible treatment option for indicated gastric GISTs patients with the advantage of faster recovery and lower economic costs.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"1-11"},"PeriodicalIF":1.7,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142951256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of liposomal as compared to standard bupivacaine for intercostal nerve blocks in patients undergoing minimally invasive thoracic surgery: a systematic review and meta-analysis.","authors":"Ruliang Chen, Zhibo Wang","doi":"10.1080/13645706.2024.2440910","DOIUrl":"https://doi.org/10.1080/13645706.2024.2440910","url":null,"abstract":"<p><strong>Background: </strong>This review aimed to provide evidence on the efficacy of liposomal bupivacaine as compared to standard bupivacaine for intercostal nerve blocks (ICB) in patients undergoing minimally invasive thoracic surgery.</p><p><strong>Methods: </strong>Randomized controlled trials (RCTs) and comparative observational studies published on the databases of PubMed, CENTRAL, Web of Science, and Embase up to June 20, 2024, were included. Total opioid consumption in morphine equivalents, pain scores, and length of hospital stay (LOS) were compared.</p><p><strong>Results: </strong>Two RCTs and eight observational studies were included. Eight hundred and four patients received liposomal bupivacaine while 631 patients received standard bupivacaine in the included studies. The meta-analysis showed that the use of liposomal bupivacaine for ICB did not reduce opioid consumption as compared to standard bupivacaine at 24 h, 48 h, and for the total duration of hospitalization. Pain scores were also not significantly different between the two groups at 24 h and 48 h. Meta-analysis showed that there was no difference in the LOS between intervention and control groups. Subgroup analysis based on study design also generated similar results.</p><p><strong>Conclusions: </strong>Mostly low-quality evidence shows that liposomal bupivacaine does not offer additional benefits over standard bupivacaine when used for ICB in patients undergoing minimally invasive thoracic surgery.</p>","PeriodicalId":18537,"journal":{"name":"Minimally Invasive Therapy & Allied Technologies","volume":" ","pages":"1-11"},"PeriodicalIF":1.7,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}