Minerva pediatrica最新文献

{"title":"Developmental and behavioral profile in a domestic adoptees sample: a new challenge for the pediatrician.","authors":"P. Ferrara, C. Cutrona, C. Guadagno, M. Amato, A. Sbordone, R. Sacco, G. Bona","doi":"10.23736/S0026-4946.16.04767-8","DOIUrl":"https://doi.org/10.23736/S0026-4946.16.04767-8","url":null,"abstract":"BACKGROUND\u0000The aim of this study is to investigate the changes of developmental and behavioral profile in a domestic adoptees sample.\u0000\u0000\u0000METHODS\u0000Thirty-six domestic adoptive families were recruited, resulting in a sample of 39 children. Families were sent a general questionnaire for collecting data related to the children demographic variables, infant's background (time spent in institutional care, age at adoption), children's health status and anthropometric measures at T0, T1, T2, and T3. Moreover, the Infant Behavior Questionnaire-Revised Very Short Form and a modified version of parent-report of Child Behavior Checklist were used to assess temperament and to detect behavioral problems.\u0000\u0000\u0000RESULTS\u0000As regards the psychopathological evaluation, behavior problems were more common in older children, especially among girls. In particular they exhibited a higher frequency of internalizing problems versus externalizing.\u0000\u0000\u0000CONCLUSIONS\u0000Children in foster care suffer discontinuity of care that negatively affects their emotional and physical development. It is important for pediatricians to be aware of the special needs of adopted children, providing adequate support to adoptive families.","PeriodicalId":18533,"journal":{"name":"Minerva pediatrica","volume":"72 5 1","pages":"433-439"},"PeriodicalIF":2.6,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48410349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pidotimod in allergic diseases.","authors":"Sara Manti,&nbsp;Giuseppe F Parisi,&nbsp;Maria Papale,&nbsp;Salvatore Leonardi","doi":"10.23736/S0026-4946.20.05967-8","DOIUrl":"https://doi.org/10.23736/S0026-4946.20.05967-8","url":null,"abstract":"<p><p>The rising incidence of allergic disease requires more specific, effective and safe therapeutic strategies. In this regard, several kinds of biologically active substances, commonly known as immunostimulants, have been introduced for the prevention and treatment of allergic diseases in pediatric population. Among the heterogeneous group of biologically active molecules to date available, pidotimod (Axil, Valeas S.p.A, Milan) is proved to be able to ameliorate both innate and adaptive immunity and enhances the immune system properties often impaired in patients with allergic disorders.</p>","PeriodicalId":18533,"journal":{"name":"Minerva pediatrica","volume":"72 5","pages":"358-363"},"PeriodicalIF":2.6,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38209491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What's new about etiopathogenesis of musculoskeletal injuries in adolescent athletes?","authors":"M. Turati, Linda Boerci, M. Piatti, N. Zanchi, G. Zatti, F. Accadbled, M. Bigoni","doi":"10.23736/S0026-4946.20.05944-7","DOIUrl":"https://doi.org/10.23736/S0026-4946.20.05944-7","url":null,"abstract":"","PeriodicalId":18533,"journal":{"name":"Minerva pediatrica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43075061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Covid-19 and kawasaki disease: is there a need for revising treatment guidelines?","authors":"R. Mormile","doi":"10.23736/S0026-4946.20.05914-9","DOIUrl":"https://doi.org/10.23736/S0026-4946.20.05914-9","url":null,"abstract":"","PeriodicalId":18533,"journal":{"name":"Minerva pediatrica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46693412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Canned tuna tolerance in children with IgE-mediated fish allergy: an allergological and nutritional view.","authors":"Luca Pecoraro,&nbsp;Laura Tenero,&nbsp;Angelo Pietrobelli,&nbsp;Luca Dalle Carbonare,&nbsp;Sarah Czernin,&nbsp;Kurt Widhalm,&nbsp;Alberto Alvarez-Perea,&nbsp;Giorgio Piacentini","doi":"10.23736/S0026-4946.20.05972-1","DOIUrl":"https://doi.org/10.23736/S0026-4946.20.05972-1","url":null,"abstract":"<p><p>Scientific research, diagnostic tools and clinical experience have shown that children suffering from IgE-mediated fish allergy do not need to follow a strict exclusion diet. In fact, they could tolerate some species of fish, which could be reintroduced in the diet by verifying their tolerance with an oral food challenge in a clinical setting. Consequently, it is possible to look a new insight on diagnosis and management of IgE-mediated fish allergy in children, considering the use of canned tuna in clinical settings. Authors performed a literature search through the Cochrane Library and Medline/PubMed databases. All quantitative and qualitative pediatric studies involving diagnosis and management of IgE-mediated fish allergy and the use of canned tuna in clinical settings were considered. Articles related to allergological and nutritional features of fish, and especially canned tuna, were selected. This research was conducted on May 2020. Canned tuna shows peculiar allergological and nutritional characteristics. Relating to allergy, canning process, characterized by cooking the fish under pressure for a time equal to about 7 hours, can lead a conformational change in parvalbumin, making it less allergenic. In terms of nutrition, canned tuna contains B, D and A vitamins and, above all, omega-3 fatty acids and shows a favourable and significantly sustainable nutritional profile. Lower allergenicity, adequate nutritional value and its rich availability in markets at reasonable costs, could make the use of canned tuna as a solution with an excellent risk/benefit ratio in the field of IgE-mediated fish allergy.</p>","PeriodicalId":18533,"journal":{"name":"Minerva pediatrica","volume":"72 5","pages":"408-415"},"PeriodicalIF":2.6,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38178594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical features and physiotherapy management for Covid-19 in children.","authors":"Paulo Magalhães, F. Lanza, Bárbara Bernardo Figueirêdo","doi":"10.23736/S0026-4946.20.06100-9","DOIUrl":"https://doi.org/10.23736/S0026-4946.20.06100-9","url":null,"abstract":"BACKGROUND\u0000COVID-19 has quickly become a worldwide threat to health, travel, and commerce. Studies adressing the clinical-functional presentation of viral infection and physiotherapy management in children are scarce. The purpose statement was to provide current perspectives on the physiotherapy interventions for managing children based on COVID-19 evidences.\u0000\u0000\u0000METHODS\u0000In this review, databases were searched between 1th January and 26 th March 2020. The following descriptors were considered: (novel coronavirus); (novel corona virus); Coronavirus; (corona vírus); 2019-nCoV; nCovor; COVID-19; SARSCoV-2; in the electronic databases National Library of Medicine (PubMed/Medline), Scientific Electronic Library Online (SciELO) and Physiotherapy Evidence Database (PEDro). The results were described through the International Classification of Functioning, Disability and Health.\u0000\u0000\u0000RESULTS\u000016 papers were included in this review. COVID-19 seems to lead to restriction of participation and interfere in tasks, such as recreation and leisure activities, respiratory muscle function and exercise tolerance. Personal protective equipments and contact precautions are important part of treatment. Effective oxygen therapy should be given immediately in presence of hypoxia. Nasal high-flow oxygen therapy, non-invasive ventilation, lung-protective ventilation strategies and prone position, should be undertaken when necessary under appropriate conditions. Airway clearance techniques should be administered only strictly needed and early activities must be encouraged.\u0000\u0000\u0000CONCLUSIONS\u0000Potential physiotherapy interventions for children with COVID-19/SARS-CoV-2 consist on ventilatory management, airway clearance techniques and early activities and mobilization.","PeriodicalId":18533,"journal":{"name":"Minerva pediatrica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45735100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salbutamol combined with budesonide in treatment of pediatric bronchial asthma and its effect on eosinophils.","authors":"Suihua Li, Qing-xiu Mei, D. Qian, Xianghong Huang, C. Fan, J. Quan","doi":"10.23736/S0026-4946.20.06003-X","DOIUrl":"https://doi.org/10.23736/S0026-4946.20.06003-X","url":null,"abstract":"BACKGROUND\u0000To investigate and discuss the salbutamol combined with budesonide in treatment of pediatric bronchial asthma (BA) and its effect on eosinophils (EOS).\u0000\u0000\u0000METHODS\u000098 BA children admitted and treated in our hospital from July 2016 to June 2017 were collected and divided into control group (n=49) and observation group (n=49) according to random number table. The children in control group were treated with budesonide and those in observation group were treated with salbutamol combined with budesonide. The clinical efficacy, pulmonary functions and levels of T-lymphocyte subsets [including cluster of differentiation 3 (CD3)+, CD4+, CD8+ and CD4+/CD8+] in the immune system between two groups were compared after the treatment; the levels of eosinophil cationic protein (ECP) and eotaxin in the children were compared before the treatment and at 1, 4 and 8 weeks after the treatment; the changes in EOS counts in blood and induced sputum of the children before and after the treatment were compared, and the EOS apoptosis rate was compared at 1, 4 and 8 weeks after the treatment.\u0000\u0000\u0000RESULTS\u0000The effective rate of treatment in observation group was significantly higher than that in control group (p<0.05). After the treatment, the indexes of pulmonary function in observation group were obviously better than those in control group (p<0.05). Compared with those in control group, the levels of CD3+, CD4+ and CD4+/CD8+ of the children in observation group were elevated remarkably, while the CD8+ level was lowered (p<0.05). The levels of ECP and eotaxin in the two groups were decreased after the treatment compared with those before the treatment, and the levels in observation group were superior to those in control group (p<0.05). After the treatment, the EOS counts of the both groups of children were lower than those before the treatment, and the decrease in observation group was more notable than that in control group. At 1, 4 and 8 weeks after the treatment, the EOS apoptosis rate in observation group was obviously higher than that in control group (p<0.05).\u0000\u0000\u0000CONCLUSIONS\u0000The treatment of salbutamol combined with budesonide for pediatric BA has significant therapeutic effects; it can restore the pulmonary functions rapidly and improve the immunity of the lung, reduce the levels of eotaxin, ECP and EOS of the child patients and promote EOS apoptosis.","PeriodicalId":18533,"journal":{"name":"Minerva pediatrica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2020-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47295158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Henoch-Schönlein purpura in Saudi Arabia the characteristics and rare vital organ involvement: a literature review.","authors":"Ashwaq Al E'ed","doi":"10.23736/S0026-4946.20.05962-9","DOIUrl":"https://doi.org/10.23736/S0026-4946.20.05962-9","url":null,"abstract":"Henoch-Schönlein purpura (HSP) is the most common small vessel vasculitis in children with an annual incidence of between 10 and 30 per 100,000. It is an inflammation that affects many organs primarily in the skin, gastrointestinal (GI) tract, musculoskeletal, also vital organs like kidneys and lungs which may lead to chronic kidney disease and pulmonary hemorrhage. In this review, we are showing the characteristics of Saudi patients with HSP and the relation with preceding infections, gender, and seasonal variations in addition to the common and most severe systemic involvements. We found cases that were challenging to diagnose and others with unfortunate fetal complications.","PeriodicalId":18533,"journal":{"name":"Minerva pediatrica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2020-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41643383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between sleep difficulty and school, sports and traffic injuries in early adolescents: a population-based study in north-eastern France.","authors":"Kénora Chau","doi":"10.23736/S0026-4946.20.05779-5","DOIUrl":"https://doi.org/10.23736/S0026-4946.20.05779-5","url":null,"abstract":"","PeriodicalId":18533,"journal":{"name":"Minerva pediatrica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2020-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43158352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extracorporeal membrane oxygenation for immunocompromised children with acute respiratory distress syndrome: a French referral center cohort.","authors":"B. Robert, I. Guellec, J. Jegard, S. Jean, J. Guilbert, Yohan Sorèze, J. Starck, Jean-Eudes Piloquet, P. Léger, J. Rambaud","doi":"10.23736/S0026-4946.20.05725-4","DOIUrl":"https://doi.org/10.23736/S0026-4946.20.05725-4","url":null,"abstract":"BACKGROUND\u0000Immunocompromised children are likely to develop a refractory acute respiratory distress syndrome (ARDS). The usefulness of providing extracorporeal life support (ECLS) to these patients is a subject of debate. The aim of our study was to report the outcomes and to compare factors associated with mortality between immunocompromised and non-immunocompromised children supported with veno-venous ECMO.\u0000\u0000\u0000METHODS\u0000We performed a retrospective monocentric study in the French pediatric ECMO center of Armand Trousseau Hospital, including all pediatric patients aged from 1 month to 18 years requiring ECLS for ARDS.\u0000\u0000\u0000RESULTS\u0000Between 2007 and 2018, one hundred and eleven (111) patients underwent ECMO for respiratory failure; among them twenty-five (25) were immunocompromised. Survival rate at 6 months after intensive care discharge was significantly lower for immunocompromised patients compared to non-immunocompromised ones (41.7% vs. 62.8%; p = 0.04). ARDS severity was similar between the 2 groups. Fungal pneumonias were reported only in immunocompromised patients (12.5% versus 0% in the control group; p = 0.001). Bleeding complications were significantly more frequent in the immunocompromised group and blood product transfusions were also more frequently required in this group.\u0000\u0000\u0000CONCLUSIONS\u0000Six months after intensive care discharge, survival rate of immunocompromised children supported with ECMO for pediatric ARDS is lower than for nonimmunocompromised patients. But, the expectation for a favorable outcome is real and it is worth it if their condition is likely to be compatible with a good long-term quality of life.","PeriodicalId":18533,"journal":{"name":"Minerva pediatrica","volume":"1 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68827264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}