Microbiology and Molecular Biology Reviews最新文献_第10页

A Brief History of the Discovery of RNA-Mediated Antiviral Immune Defenses in Vector Mosquitos. 病媒蚊 RNA 介导的抗病毒免疫防御系统的发现简史。

IF 12.9 1区生物学

Microbiology and Molecular Biology Reviews Pub Date : 2023-03-21 Epub Date: 2022-12-13 DOI: 10.1128/mmbr.00191-21

Carol D Blair

{"title":"A Brief History of the Discovery of RNA-Mediated Antiviral Immune Defenses in Vector Mosquitos.","authors":"Carol D Blair","doi":"10.1128/mmbr.00191-21","DOIUrl":"10.1128/mmbr.00191-21","url":null,"abstract":"Arthropod-borne viruses (arboviruses) persist in a natural cycle that includes infections of humans or other vertebrates and transmission between vertebrates by infected arthropods, most commonly mosquitos. Arboviruses can cause serious, sometimes fatal diseases in humans and other vertebrates but cause little pathology in their mosquito vectors. Knowledge of the interactions between mosquito vectors and the arboviruses that they transmit is an important facet of developing schemes to control transmission. Mosquito innate immune responses to virus infection modulate virus replication in the vector, and understanding the components and mechanisms of the immune response could lead to improved methods for interrupting the transmission cycle. The most important aspect of mosquito antiviral defense is the exogenous small interfering RNA (exo-siRNA) pathway, one arm of the RNA interference (RNAi) silencing response. Our research as well as that of many other groups over the past 25 years to define this pathway are reviewed here. A more recently recognized but less well-understood RNA-mediated mosquito defense against arbovirus infections, the PIWI-interacting RNA (piRNA) pathway, is also described.","PeriodicalId":18520,"journal":{"name":"Microbiology and Molecular Biology Reviews","volume":"87 1","pages":"e0019121"},"PeriodicalIF":12.9,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9296496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Methyl-Based Methanogenesis: an Ecological and Genomic Review. 基于甲基的甲烷生成：生态学和基因组学回顾。

IF 8 1区生物学

Microbiology and Molecular Biology Reviews Pub Date : 2023-03-21 Epub Date: 2023-01-24 DOI: 10.1128/mmbr.00024-22

Clifton P Bueno de Mesquita, Dongying Wu, Susannah G Tringe

引用次数: 0

The Fission Yeast Mating-Type Switching Motto: "One-for-Two" and "Two-for-One". 裂变酵母的交配类型转换格言："一换二 "和 "二换一"。

IF 12.9 1区生物学

Microbiology and Molecular Biology Reviews Pub Date : 2023-03-21 Epub Date: 2023-01-11 DOI: 10.1128/mmbr.00008-21

Benoît Arcangioli, Serge Gangloff

引用次数: 3

2022 Acknowledgment of MMBR Reviewers. 2022感谢MMBR审稿人。

IF 12.9 1区生物学

Microbiology and Molecular Biology Reviews Pub Date : 2022-12-21 DOI: 10.1128/mmbr.00162-22

Corrella S Detweiler

引用次数: 0

How It All Begins: Bacterial Factors Mediating the Colonization of Invertebrate Hosts by Beneficial Symbionts. 一切是如何开始的：有益共生体介导无脊椎动物宿主定殖的细菌因素。

IF 12.9 1区生物学

Microbiology and Molecular Biology Reviews Pub Date : 2022-12-21 Epub Date: 2022-10-27 DOI: 10.1128/mmbr.00126-21

Ramya Ganesan, Jürgen C Wierz, Martin Kaltenpoth, Laura V Flórez

{"title":"How It All Begins: Bacterial Factors Mediating the Colonization of Invertebrate Hosts by Beneficial Symbionts.","authors":"Ramya Ganesan, Jürgen C Wierz, Martin Kaltenpoth, Laura V Flórez","doi":"10.1128/mmbr.00126-21","DOIUrl":"10.1128/mmbr.00126-21","url":null,"abstract":"Beneficial associations with bacteria are widespread across animals, spanning a range of symbiont localizations, transmission routes, and functions. While some of these associations have evolved into obligate relationships with permanent symbiont localization within the host, the majority require colonization of every host generation from the environment or via maternal provisions. Across the broad diversity of host species and tissue types that beneficial bacteria can colonize, there are some highly specialized strategies for establishment yet also some common patterns in the molecular basis of colonization. This review focuses on the mechanisms underlying the early stage of beneficial bacterium-invertebrate associations, from initial contact to the establishment of the symbionts in a specific location of the host's body. We first reflect on general selective pressures that can drive the transition from a free-living to a host-associated lifestyle in bacteria. We then cover bacterial molecular factors for colonization in symbioses from both model and nonmodel invertebrate systems where these have been studied, including terrestrial and aquatic host taxa. Finally, we discuss how interactions between multiple colonizing bacteria and priority effects can influence colonization. Taking the bacterial perspective, we emphasize the importance of developing new experimentally tractable systems to derive general insights into the ecological factors and molecular adaptations underlying the origin and establishment of beneficial symbioses in animals.","PeriodicalId":18520,"journal":{"name":"Microbiology and Molecular Biology Reviews","volume":"86 4","pages":"e0012621"},"PeriodicalIF":12.9,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769632/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10454680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Outer Membrane Vesicles: Biogenesis, Functions, and Issues. 外膜囊泡：生物学发生、功能和问题。

IF 8 1区生物学

Microbiology and Molecular Biology Reviews Pub Date : 2022-12-21 Epub Date: 2022-09-26 DOI: 10.1128/mmbr.00032-22

Rokas Juodeikis, Simon R Carding

引用次数: 0

Enzyme Discovery in Anaerobic Fungi (Neocallimastigomycetes) Enables Lignocellulosic Biorefinery Innovation. 厌氧真菌(neocallimastigomyetes)中酶的发现促进了木质纤维素生物炼制的创新。

IF 12.9 1区生物学

Microbiology and Molecular Biology Reviews Pub Date : 2022-12-21 DOI: 10.1128/mmbr.00041-22

Thomas S Lankiewicz, Stephen P Lillington, Michelle A O'Malley

{"title":"Enzyme Discovery in Anaerobic Fungi (Neocallimastigomycetes) Enables Lignocellulosic Biorefinery Innovation.","authors":"Thomas S Lankiewicz, Stephen P Lillington, Michelle A O'Malley","doi":"10.1128/mmbr.00041-22","DOIUrl":"https://doi.org/10.1128/mmbr.00041-22","url":null,"abstract":"Lignocellulosic biorefineries require innovative solutions to realize their full potential, and the discovery of novel lignocellulose-active enzymes could improve biorefinery deconstruction processes. Enzymatic deconstruction of plant cell walls is challenging, as noncarbohydrate linkages in hemicellulosic sidechains and lignin protect labile carbohydrates from hydrolysis. SUMMARY Lignocellulosic biorefineries require innovative solutions to realize their full potential, and the discovery of novel lignocellulose-active enzymes could improve biorefinery deconstruction processes. Enzymatic deconstruction of plant cell walls is challenging, as noncarbohydrate linkages in hemicellulosic sidechains and lignin protect labile carbohydrates from hydrolysis. Highly specialized microbes that degrade plant biomass are attractive sources of enzymes for improving lignocellulose deconstruction, and the anaerobic gut fungi (Neocallimastigomycetes) stand out as having great potential for harboring novel lignocellulose-active enzymes. We discuss the known aspects of Neocallimastigomycetes lignocellulose deconstruction, including their extensive carbohydrate-active enzyme content, proficiency at deconstructing complex lignocellulose, unique physiology, synergistic enzyme complexes, and sizeable uncharacterized gene content. Progress describing Neocallimastigomycetes and their enzymes has been rapid in recent years, and it will only continue to expand. In particular, direct manipulation of anaerobic fungal genomes, effective heterologous expression of anaerobic fungal enzymes, and the ability to directly relate chemical changes in lignocellulose to fungal gene regulation will accelerate the discovery and subsequent deployment of Neocallimastigomycetes lignocellulose-active enzymes.","PeriodicalId":18520,"journal":{"name":"Microbiology and Molecular Biology Reviews","volume":"86 4","pages":"e0004122"},"PeriodicalIF":12.9,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769567/pdf/mmbr.00041-22.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10191181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Harnessing the Power of Model Organisms To Unravel Microbial Functions in the Coral Holobiont. 利用模式生物的力量解开珊瑚Holobiont中的微生物功能。

IF 12.9 1区生物学

Microbiology and Molecular Biology Reviews Pub Date : 2022-12-21 Epub Date: 2022-10-26 DOI: 10.1128/mmbr.00053-22

Giulia Puntin, Michael Sweet, Sebastian Fraune, Mónica Medina, Koty Sharp, Virginia M Weis, Maren Ziegler

{"title":"Harnessing the Power of Model Organisms To Unravel Microbial Functions in the Coral Holobiont.","authors":"Giulia Puntin, Michael Sweet, Sebastian Fraune, Mónica Medina, Koty Sharp, Virginia M Weis, Maren Ziegler","doi":"10.1128/mmbr.00053-22","DOIUrl":"10.1128/mmbr.00053-22","url":null,"abstract":"Stony corals build the framework of coral reefs, ecosystems of immense ecological and economic importance. The existence of these ecosystems is threatened by climate change and other anthropogenic stressors that manifest in microbial dysbiosis such as coral bleaching and disease, often leading to coral mortality. Despite a significant amount of research, the mechanisms ultimately underlying these destructive phenomena, and what could prevent or mitigate them, remain to be resolved. This is mostly due to practical challenges in experimentation on corals and the highly complex nature of the coral holobiont that also includes bacteria, archaea, protists, and viruses. While the overall importance of these partners is well recognized, their specific contributions to holobiont functioning and their interspecific dynamics remain largely unexplored. Here, we review the potential of adopting model organisms as more tractable systems to address these knowledge gaps. We draw on parallels from the broader biological and biomedical fields to guide the establishment, implementation, and integration of new and emerging model organisms with the aim of addressing the specific needs of coral research. We evaluate the cnidarian models Hydra, Aiptasia, Cassiopea, and Astrangia poculata; review the fast-evolving field of coral tissue and cell cultures; and propose a framework for the establishment of \"true\" tropical reef-building coral models. Based on this assessment, we also suggest future research to address key aspects limiting our ability to understand and hence improve the response of reef-building corals to future ocean conditions.","PeriodicalId":18520,"journal":{"name":"Microbiology and Molecular Biology Reviews","volume":"86 4","pages":"e0005322"},"PeriodicalIF":12.9,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10640821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

The Role of Chromatin and Transcriptional Control in the Formation of Sexual Fruiting Bodies in Fungi. 染色质和转录调控在真菌有性子实体形成中的作用。

IF 8 1区生物学

Microbiology and Molecular Biology Reviews Pub Date : 2022-12-21 Epub Date: 2022-11-21 DOI: 10.1128/mmbr.00104-22

Minou Nowrousian

{"title":"The Role of Chromatin and Transcriptional Control in the Formation of Sexual Fruiting Bodies in Fungi.","authors":"Minou Nowrousian","doi":"10.1128/mmbr.00104-22","DOIUrl":"10.1128/mmbr.00104-22","url":null,"abstract":"Fungal fruiting bodies are complex, three-dimensional structures that arise from a less complex vegetative mycelium. Their formation requires the coordinated action of many genes and their gene products, and fruiting body formation is accompanied by major changes in the transcriptome. In recent years, numerous transcription factor genes as well as chromatin modifier genes that play a role in fruiting body morphogenesis were identified, and through research on several model organisms, the underlying regulatory networks that integrate chromatin structure, gene expression, and cell differentiation are becoming clearer. This review gives a summary of the current state of research on the role of transcriptional control and chromatin structure in fruiting body development. In the first part, insights from transcriptomics analyses are described, with a focus on comparative transcriptomics. In the second part, examples of more detailed functional characterizations of the role of chromatin modifiers and/or transcription factors in several model organisms (Neurospora crassa, Aspergillus nidulans, Sordaria macrospora, Coprinopsis cinerea, and Schizophyllum commune) that have led to a better understanding of regulatory networks at the level of chromatin structure and transcription are discussed.","PeriodicalId":18520,"journal":{"name":"Microbiology and Molecular Biology Reviews","volume":"86 4","pages":"e0010422"},"PeriodicalIF":8.0,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9549194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pheromone Response and Mating Behavior in Fission Yeast. 裂变酵母的信息素反应和交配行为。

IF 8 1区生物学

Microbiology and Molecular Biology Reviews Pub Date : 2022-12-21 Epub Date: 2022-12-05 DOI: 10.1128/mmbr.00130-22

Taisuke Seike, Hironori Niki

{"title":"Pheromone Response and Mating Behavior in Fission Yeast.","authors":"Taisuke Seike, Hironori Niki","doi":"10.1128/mmbr.00130-22","DOIUrl":"10.1128/mmbr.00130-22","url":null,"abstract":"Most ascomycete fungi, including the fission yeast Schizosaccharomyces pombe, secrete two peptidyl mating pheromones: C-terminally modified and unmodified peptides. S. pombe has two mating types, plus and minus, which secrete two different pheromones, P-factor (unmodified) and M-factor (modified), respectively. These pheromones are specifically recognized by receptors on the cell surface of cells of opposite mating types, which trigger a pheromone response. Recognition between pheromones and their corresponding receptors is important for mate discrimination; therefore, genetic changes in pheromone or receptor genes affect mate recognition and cause reproductive isolation that limits gene flow between populations. Such genetic variation in recognition via the pheromone/receptor system may drive speciation. Our recent studies reported that two pheromone receptors in S. pombe might have different stringencies in pheromone recognition. In this review, we focus on the molecular mechanism of pheromone response and mating behavior, emphasizing pheromone diversification and its impact on reproductive isolation in S. pombe and closely related fission yeast species. We speculate that the \"asymmetric\" system might allow flexible adaptation to pheromone mutational changes while maintaining stringent recognition of mating partners. The loss of pheromone activity results in the extinction of an organism's lineage. Therefore, genetic changes in pheromones and their receptors may occur gradually and/or coincidently before speciation. Our findings suggest that the M-factor plays an important role in partner discrimination, whereas P-factor communication allows flexible adaptation to create variations in S. pombe. Our inferences provide new insights into the evolutionary mechanisms underlying pheromone diversification.","PeriodicalId":18520,"journal":{"name":"Microbiology and Molecular Biology Reviews","volume":"86 4","pages":"e0013022"},"PeriodicalIF":8.0,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10458957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0