Medical Science Monitor Basic Research最新文献

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Exploring the Impact of the COVID-19 Pandemic on Academic Burnout Among Nursing College Students in China: A Web-Based Survey. 新冠肺炎疫情对中国护理大学生学业倦怠的影响:基于网络的调查
IF 2.8
Medical Science Monitor Basic Research Pub Date : 2023-10-30 DOI: 10.12659/MSMBR.940997
Huan Liu, Ziyu Zhang, Chenru Chi, Xiubin Tao, Ming Zhang
{"title":"Exploring the Impact of the COVID-19 Pandemic on Academic Burnout Among Nursing College Students in China: A Web-Based Survey.","authors":"Huan Liu, Ziyu Zhang, Chenru Chi, Xiubin Tao, Ming Zhang","doi":"10.12659/MSMBR.940997","DOIUrl":"10.12659/MSMBR.940997","url":null,"abstract":"<p><p>BACKGROUND The COVID-19 pandemic has brought changes and challenges to nursing students. However, little is known about the prevalence of academic burnout among nursing students in this challenging circumstance. This study aimed to assess nursing student academic burnout and its influencing factors. MATERIAL AND METHODS We conducted a sample survey of a 4-year undergraduate nursing university in Wuhu, Anhui Province, China. The social-demographic information questionnaire, Academic Burnout Scale, Connor-Davidson Resilience Scale, Impact of Event Scale-6, Patient Health Questionnaire-2, and Professional Identity Scale were used. Stepwise multiple linear regression was used to clarify the relationship among sociodemographic characteristics, resilience, and academic burnout. RESULTS Of all the study participants, 51.30% had a certain degree of academic burnout. Academic year, satisfaction with specialty, satisfaction with online learning, professional identity, and psychological resilience were negatively correlated with academic burnout among nursing students. Depression was positively correlated with academic burnout. CONCLUSIONS Nursing students had a high degree of academic burnout. Academic year, satisfaction with specialty, satisfaction with online learning, professional identity, and psychological resilience were protective factors that reduced nursing students' academic burnout.</p>","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"29 ","pages":"e940997"},"PeriodicalIF":2.8,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107591687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anxiety and Depression Survey and Analysis of Hospital Staff in a Designated Hospital in Shannan City During the COVID-19 Pandemic. 新冠肺炎大流行期间山南市某定点医院医护人员焦虑抑郁状况调查分析
IF 2.8
Medical Science Monitor Basic Research Pub Date : 2023-05-18 DOI: 10.12659/MSMBR.939514
Peijin Zhang, Liling Tang, Deji Ciren
{"title":"Anxiety and Depression Survey and Analysis of Hospital Staff in a Designated Hospital in Shannan City During the COVID-19 Pandemic.","authors":"Peijin Zhang,&nbsp;Liling Tang,&nbsp;Deji Ciren","doi":"10.12659/MSMBR.939514","DOIUrl":"https://doi.org/10.12659/MSMBR.939514","url":null,"abstract":"<p><p>BACKGROUND The aim of this study was to evaluate the psychological status of anxiety and depression of hospital staff in the designated hospital in the city of Shannan during the COVID-19 pandemic in order to provide a theoretical basis for effective psychological intervention. MATERIAL AND METHODS A cross-sectional survey was performed from September 10 to 16, 2022, by administering an online questionnaire to the hospital staff on duty in the hospital. We collected participants' demographic and general information. The Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) were used to investigate the anxiety and depression of hospital staff. RESULTS Among 267 hospital staff, anxiety was found in 98 individuals, with a prevalence of 36.70%. Depression was found in 170 individuals, with a prevalence of 63.67%. Anxiety combined with depression was found in 84 individuals, with a prevalence of 31.46%. The prevalence of depression was higher in women, Tibetan personnel, hospital staff with primary or lower titles, staff without career establishment, and non-aid Tibetan personnel, and the differences were all statistically significant (P.</p>","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"29 ","pages":"e939514"},"PeriodicalIF":2.8,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/02/2c/medscimonitbasicres-29-e939514.PMC10204610.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9556324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Questionnaire-Based Study to Compare the Psychological Effects of 6 Weeks of Exercise in 123 Chinese College Students. 123名中国大学生6周运动心理效果的问卷研究
IF 2.8
Medical Science Monitor Basic Research Pub Date : 2023-03-22 DOI: 10.12659/MSMBR.939096
Mei Xue Wei, Zhen Liu
{"title":"A Questionnaire-Based Study to Compare the Psychological Effects of 6 Weeks of Exercise in 123 Chinese College Students.","authors":"Mei Xue Wei,&nbsp;Zhen Liu","doi":"10.12659/MSMBR.939096","DOIUrl":"https://doi.org/10.12659/MSMBR.939096","url":null,"abstract":"<p><p>BACKGROUND The aim of this study was to explore the mechanisms underlying the association between exercise intervention and mental health, and our questionnaire-based study aimed to compare the psychological effects of 6 weeks of exercise among 123 Chinese university students. MATERIAL AND METHODS A total of 123 college students were randomly divided into the experimental group (80 patients) and the control group (43 patients). The experimental group participated in a 6-week exercise intervention, and the control group received no intervention. Questionnaires were used to study emotion regulation and mental health. RESULTS The exercise intervention has a significant effect on reducing the anxiety and depression levels of college students [F(1,122)=10.83, p.</p>","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"29 ","pages":"e939096"},"PeriodicalIF":2.8,"publicationDate":"2023-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cb/f6/medscimonitbasicres-29-e939096.PMC10041936.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9264013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study of 60 Adult Patients to Compare Standard Postoperative Clinical Assessment with Train-of-Four Ratio ≥0.9 on Patient Outcomes Using Postoperative Spirometry and Neuromuscular Function Measurements Following Extubation. 60例成人患者拔管后肺量测定和神经肌肉功能测量比较标准术后临床评估与四训练比值≥0.9患者预后的研究。
IF 2.8
Medical Science Monitor Basic Research Pub Date : 2023-03-08 DOI: 10.12659/MSMBR.938849
Chunlong Chen, Qingzhen Liu, Hong Fan, Zhiyang Yu, Xueyan Leng, Lidong Zhang, Zhiqiang Zhou
{"title":"Study of 60 Adult Patients to Compare Standard Postoperative Clinical Assessment with Train-of-Four Ratio ≥0.9 on Patient Outcomes Using Postoperative Spirometry and Neuromuscular Function Measurements Following Extubation.","authors":"Chunlong Chen,&nbsp;Qingzhen Liu,&nbsp;Hong Fan,&nbsp;Zhiyang Yu,&nbsp;Xueyan Leng,&nbsp;Lidong Zhang,&nbsp;Zhiqiang Zhou","doi":"10.12659/MSMBR.938849","DOIUrl":"https://doi.org/10.12659/MSMBR.938849","url":null,"abstract":"<p><p>BACKGROUND Postoperative tracheal extubation requires optimal timing to ensure patient safety and normal muscle function. The train-of-four ratio (TOFR) of the fourth muscle response compared with the first indicates a non-depolarizing neuromuscular block, and a ratio ≥0.9 can be used as an objective measurement of neuromuscular reversal. This study of 60 adult patients who underwent elective surgery with general anesthesia that included the neuromuscular blocking agent cisatracurium aimed to compare standard postoperative clinical assessment with the TOFR ≥0.9 on patient outcomes using postoperative neuromuscular function assessed by grip strength and ability to sit up unaided and spirometry measurements following extubation. MATERIAL AND METHODS The 30 patients extubated postoperatively in the TOF group were required to have a TOFR ≥0.9, while the 30 patients in the clinical assessment group were awake and following simple commands and had a 5-second head lift and spontaneous breathing with acceptable oxygenation. The main outcomes were the incentive spirometry and grip strength and ability to sit up unaided measured at 10, 30, 50 min and 24 h after extubation. RESULTS The groups had no difference in recovery path of incentive spirometry volume (P=0.072) and no difference in postoperative incentive spirometry decrease from baseline except at 10 min after extubation (P=0.005). There was no difference in handgrip strength and independent sitting between groups. CONCLUSIONS The findings showed that using the TOF ratio ≥0.9 before extubation did not improve early postoperative strength quantified by spirometry volume, handgrip strength, and proportion of unaided sitting.</p>","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"29 ","pages":"e938849"},"PeriodicalIF":2.8,"publicationDate":"2023-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/86/f7/medscimonitbasicres-29-e938849.PMC10010054.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9118093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Prospective Study of 73 Patients to Compare Forward Head Angle, Forward Shoulder Angle, Maximal Inspiratory Pressure, and Self-Reported Breathing-Related Symptoms Before and After Open-Heart Surgery. 一项73例患者的前瞻性研究,比较前头角、前肩角、最大吸气压力和心内直视手术前后自我报告的呼吸相关症状。
IF 2.8
Medical Science Monitor Basic Research Pub Date : 2023-02-07 DOI: 10.12659/MSMBR.938802
Bussakorn Thanasarn, Wittawat Pibul, Chitima Kulchanarat, Dusarkorn Piathip, Kornanong Yuenyongchaiwat
{"title":"A Prospective Study of 73 Patients to Compare Forward Head Angle, Forward Shoulder Angle, Maximal Inspiratory Pressure, and Self-Reported Breathing-Related Symptoms Before and After Open-Heart Surgery.","authors":"Bussakorn Thanasarn,&nbsp;Wittawat Pibul,&nbsp;Chitima Kulchanarat,&nbsp;Dusarkorn Piathip,&nbsp;Kornanong Yuenyongchaiwat","doi":"10.12659/MSMBR.938802","DOIUrl":"https://doi.org/10.12659/MSMBR.938802","url":null,"abstract":"<p><p>BACKGROUND Patients who undergo open-heart surgery often experience widespread musculoskeletal and pulmonary complications. These can interfere with their functioning, resulting in soft tissue changes, worsening postural changes, and poor respiratory performance. Therefore, the prospective study aimed to compare forward head angle (FHA) and forward shoulder angle (FSA), maximal inspiratory pressure (MIP), and self-reported breathing dysfunction before and after open-heart surgery. MATERIAL AND METHODS In a prospective observational study of 106 patients, men and women scheduled for open-heart surgery were enrolled. Prior to surgery and before discharge from the hospital, all patients were required to assess FHA and FSA using 2-dimensional motion analysis software, MIP using a respiratory pressure meter, and breathing dysfunction using the 25-item Self Evaluation of Breathing Questionnaire (SEBQ). Paired t test was used to compare differences between before and after surgery. To evaluate associations, logistic regression analysis was performed. RESULTS Of the 106 patients recruited, 73 completed the study. FHA (-Δ6.55±4.77, P.</p>","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"29 ","pages":"e938802"},"PeriodicalIF":2.8,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/69/53/medscimonitbasicres-29-e938802.PMC9921079.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10804588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Associated Factors of Depression Among Frontline Nurses in Wuhan 6 Months After the Outbreak of COVID-19: A Cross-Sectional Study. 新冠肺炎疫情爆发后6个月武汉市一线护士抑郁患病率及相关因素的横断面研究
IF 2.8
Medical Science Monitor Basic Research Pub Date : 2023-01-10 DOI: 10.12659/MSMBR.938633
Huan Liu, Zhiqing Zhou, Yan Liu, Xiubin Tao, Yuxin Zhan, Ming Zhang
{"title":"Prevalence and Associated Factors of Depression Among Frontline Nurses in Wuhan 6 Months After the Outbreak of COVID-19: A Cross-Sectional Study.","authors":"Huan Liu,&nbsp;Zhiqing Zhou,&nbsp;Yan Liu,&nbsp;Xiubin Tao,&nbsp;Yuxin Zhan,&nbsp;Ming Zhang","doi":"10.12659/MSMBR.938633","DOIUrl":"https://doi.org/10.12659/MSMBR.938633","url":null,"abstract":"<p><p>BACKGROUND Due to the COVID-19 pandemic, frontline nurses have experienced psychological problems. However, the depression of frontline nurses in Wuhan 6 months after the outbreak of COVID-19 has not been studied adequately. The purpose of this study was to investigate the depression of frontline nurses in Wuhan 6 months after the COVID-19 outbreak and to analyze possible risk and protective factors. MATERIAL AND METHODS Data were collected through Wenjuanxing from 612 frontline nurses in Wuhan national COVID-19-designated hospitals between July 27, 2020, and August 12, 2020. The levels of depression, family functioning, and psychological resilience were assessed among frontline nurses in Wuhan with a depression scale, family function scale, and 10-item psychological resilience scale, respectively. The factors associated with depressive symptoms were identified using the chi-square test and binary logistic regression analysis. RESULTS A total of 126 respondents were included in the study. The overall prevalence of depression was 25.2%. The need for mental health services was a potential risk factor for depressive symptoms, while family functioning and psychological resilience were potential protective factors. The COVID-19 pandemic poses a major challenge to the depressive symptoms of frontline nursing in Wuhan, highlighting the need for all frontline nurses in Wuhan to be screened for depression regularly for timely intervention. CONCLUSIONS To mitigate the impact of the pandemic on depression, psychological interventions for frontline nurses need to be implemented to preserve their mental health.</p>","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"29 ","pages":"e938633"},"PeriodicalIF":2.8,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/61/a1/medscimonitbasicres-29-e938633.PMC9840364.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10861023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of Estimated Glomerular Filtration Rate and Urine Albumin-to-Creatinine Ratio Based on KDIGO 2012 Guideline in a Thai Community Hospital: Prevalence of Chronic Kidney Disease and its Risk Factors. 基于KDIGO 2012指南的肾小球滤过率和尿白蛋白与肌酐比值在泰国社区医院的应用:慢性肾病的患病率及其危险因素
IF 2.8
Medical Science Monitor Basic Research Pub Date : 2022-12-08 DOI: 10.12659/MSMBR.938176
Veeravan Lekskulchai
{"title":"Use of Estimated Glomerular Filtration Rate and Urine Albumin-to-Creatinine Ratio Based on KDIGO 2012 Guideline in a Thai Community Hospital: Prevalence of Chronic Kidney Disease and its Risk Factors.","authors":"Veeravan Lekskulchai","doi":"10.12659/MSMBR.938176","DOIUrl":"https://doi.org/10.12659/MSMBR.938176","url":null,"abstract":"<p><p>BACKGROUND Kidney disease is hard to detect at its early stage; therefore, the Kidney Disease: Improving Global Outcomes (KDIGO) 2012 guideline was developed for improving care and outcomes of patients with kidney disease. This study aimed to determine clinical outcomes from applying this guideline in a community hospital service. MATERIAL AND METHODS The patients' data were extracted from their medical records and analyzed for outcomes of using the estimated glomerular filtration rate (eGFR) and urine albumin-creatinine ratio (UACR) for detecting kidney disease. RESULTS The eGFR was utilized in 36 172 patients aged ≥18 years, and 76.86% of them had normal kidney function. The prevalence of chronic kidney disease (CKD) was 8.20%; most patients (68%) with CKD were in stages 3a and 3b. The most common causes of CKD were diabetes and hypertension. The UACR was mainly used in patients with diabetes. The percentage of patients with UACR ≥3 mg/mmol creatinine alone was significantly higher than that of patients with eGFR.</p>","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"28 ","pages":"e938176"},"PeriodicalIF":2.8,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f3/f0/medscimonitbasicres-28-e938176.PMC9745955.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10424014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FLT3 Gene Mutations in Acute Myeloid Leukemia Patients in Northeast Thailand. 泰国东北部急性髓性白血病患者FLT3基因突变
IF 2.8
Medical Science Monitor Basic Research Pub Date : 2022-11-24 DOI: 10.12659/MSMBR.937446
Nang Ei Ei Aung, Supawadee Yamsri, Nattiya Teawtrakul, Piyawan Kamsaen, Supan Fucharoen
{"title":"FLT3 Gene Mutations in Acute Myeloid Leukemia Patients in Northeast Thailand.","authors":"Nang Ei Ei Aung,&nbsp;Supawadee Yamsri,&nbsp;Nattiya Teawtrakul,&nbsp;Piyawan Kamsaen,&nbsp;Supan Fucharoen","doi":"10.12659/MSMBR.937446","DOIUrl":"https://doi.org/10.12659/MSMBR.937446","url":null,"abstract":"<p><p>BACKGROUND Mutations in the FLT3 gene are associated with acute myeloid leukemia (AML). FLT3 mutations have been identified in approximately 30% of de novo AML patients, particularly those with typical karyotype and inferior prognosis. Therefore, we examined the frequencies of an internal tandem duplication (ITD) and missense mutations of the FLT3 gene and their associated clinical characteristics in patients with AML in northeast Thailand. MATERIAL AND METHODS The leftover bone marrow and/or peripheral blood specimens of 65 newly diagnosed AML patients recruited from Srinagarind Hospital, Khon Kaen University, northeast Thailand, between January 2020 and May 2021 were included in this study. FLT3-ITD and FLT3- tyrosine kinase domain (TKD) were amplified using PCR-related techniques. RESULTS The frequencies of FLT3-ITD and TKD were found to be 16.9% (11/65) and 10.8% (7/65), respectively. One patient had ITD and TKD mutations. The white blood cell count and peripheral blast percentage of FLT3-ITD-positive patients were statistically significantly higher than those of the FLT3-wild type patients, while the peripheral blast percentage of FLT3-TKD-positive patients was significantly lower. No other clinical characteristics among FLT3-positive and FLT3-wild-type patients were observed. DNA sequencing identified 4 FLT3-TKD mutations. The c.2504A>T; Asp835Val and c.2503G>C; Asp835His mutations were predicted as pathogenic mutations while the 2 novel mutations, c.2508C>A; Ile836= and c.2508C>G; Ile836Met were predicted as neutral mutations. CONCLUSIONS This study showed for the first time that FLT3-TKD mutation is common among northeast Thai AML patients. The data should prove useful for selecting efficacious targeted treatment plans for the patients.</p>","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"28 ","pages":"e937446"},"PeriodicalIF":2.8,"publicationDate":"2022-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9e/5d/medscimonitbasicres-28-e937446.PMC9707044.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10424013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Evaluation of Antimicrobial Effectiveness of Dental Cement Materials on Growth of Different Bacterial Strains. 牙骨水泥材料对不同菌种生长的抗菌效果评价。
IF 2.8
Medical Science Monitor Basic Research Pub Date : 2022-11-03 DOI: 10.12659/MSMBR.937893
Zana D Lila-Krasniqi, Rrezarta Bajrami Halili, Valeza Hamza, Sokol Krasniqi
{"title":"Evaluation of Antimicrobial Effectiveness of Dental Cement Materials on Growth of Different Bacterial Strains.","authors":"Zana D Lila-Krasniqi,&nbsp;Rrezarta Bajrami Halili,&nbsp;Valeza Hamza,&nbsp;Sokol Krasniqi","doi":"10.12659/MSMBR.937893","DOIUrl":"https://doi.org/10.12659/MSMBR.937893","url":null,"abstract":"<p><p>BACKGROUND The aim of this study was to evaluate the antimicrobial effectiveness of dental cement materials for the prevention of bacterial growth, which can cause failure of fixed cementation. MATERIAL AND METHODS We developed an agar diffusion disk test in-house to evaluate the antibacterial properties of 3 commercially available dental cement materials (Ketac, Harvard FLB, and Panavia SA Universal Dual Resin cements) compared with a negative control. The materials were tested for the inhibition against Streptococcus mutans (ATCC 10449), Streptoccocus salivarius (ATCC 25975), Enterococcus faecalis (ATCC 29212), and Lactobacilus acidophilus (ATCC 4356). The antimicrobial effectiveness of materials was expressed as the diameters of the inhibition zones around the disk. RESULTS Overall, 240 specimens were tested. All cement materials showed antimicrobial effectiveness. Different microbial strains reacted differently to the different dental cements (all P.</p>","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":" ","pages":"e937893"},"PeriodicalIF":2.8,"publicationDate":"2022-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/01/eb/medscimonitbasicres-28-e937893.PMC9642093.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40692868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Evaluation of Apical Leakage After Root Canal Obturation with Glass Ionomer, Resin, and Zinc Oxide Eugenol Sealers Combined with Thermafil. 玻璃离子、树脂、氧化锌丁香酚密封剂联合Thermafil对根管封闭后根尖渗漏的评价。
IF 2.8
Medical Science Monitor Basic Research Pub Date : 2022-06-15 DOI: 10.12659/MSMBR.936675
Violeta Vula, Miranda Stavileci, Nexhmije Ajeti, Vegim Vula, Astrit Kuçi, Kastriot Meqa
{"title":"Evaluation of Apical Leakage After Root Canal Obturation with Glass Ionomer, Resin, and Zinc Oxide Eugenol Sealers Combined with Thermafil.","authors":"Violeta Vula,&nbsp;Miranda Stavileci,&nbsp;Nexhmije Ajeti,&nbsp;Vegim Vula,&nbsp;Astrit Kuçi,&nbsp;Kastriot Meqa","doi":"10.12659/MSMBR.936675","DOIUrl":"https://doi.org/10.12659/MSMBR.936675","url":null,"abstract":"<p><p>BACKGROUND A hermetic seal at the apical terminus is required for healthy periradicular tissue. Root canal obturation sealers that are used in endodontics are based on zinc oxide eugenol, calcium hydroxide, resins, glass ionomers, silicone, or bioceramics, but no optimal sealer material has been identified to date. Therefore, the aim of this in vitro study was to evaluate apical leakage after crown-down preparation and root canal obturation with Endomethasone N, glass ionomer cement, and EndoRez sealers. MATERIAL AND METHODS For this in vitro study, we tested 92 extracted human teeth, which were divided into 3 groups after a preparation technique and obturation with Endomethasone N sealer, glass ionomer cement, and EndoRez sealer in combination with Thermafil obturator. Apical leakage was evaluated and compared among the tested groups using a dye leakage method through a stereomicroscope. The values were measured from the apex to the coronal extent of dye penetration. For statistical analysis, the t test was used for comparison of the arithmetic averages of tested groups. RESULTS After preparation with rotary files, tested groups obturated with Thermafil obturator in combination with Endomethasone sealer showed higher average dye penetration than tested groups obturated with EndoRez and glass ionomer sealer. CONCLUSIONS Although all experimental groups showed dye leakage, the glass ionomer sealer in combination with Thermafil showed the least leakage, compared with EndoRez and Endomethason N.</p>","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":" ","pages":"e936675"},"PeriodicalIF":2.8,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3c/14/medscimonitbasicres-28-e936675.PMC9208302.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40410937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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