Medical Science Monitor Basic Research最新文献_第2页

Anxiety and Depression Survey and Analysis of Hospital Staff in a Designated Hospital in Shannan City During the COVID-19 Pandemic. 新冠肺炎大流行期间山南市某定点医院医护人员焦虑抑郁状况调查分析

IF 2.8

Medical Science Monitor Basic Research Pub Date : 2023-05-18 DOI: 10.12659/MSMBR.939514

Peijin Zhang, Liling Tang, Deji Ciren

{"title":"Anxiety and Depression Survey and Analysis of Hospital Staff in a Designated Hospital in Shannan City During the COVID-19 Pandemic.","authors":"Peijin Zhang, Liling Tang, Deji Ciren","doi":"10.12659/MSMBR.939514","DOIUrl":"https://doi.org/10.12659/MSMBR.939514","url":null,"abstract":"BACKGROUND The aim of this study was to evaluate the psychological status of anxiety and depression of hospital staff in the designated hospital in the city of Shannan during the COVID-19 pandemic in order to provide a theoretical basis for effective psychological intervention. MATERIAL AND METHODS A cross-sectional survey was performed from September 10 to 16, 2022, by administering an online questionnaire to the hospital staff on duty in the hospital. We collected participants' demographic and general information. The Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) were used to investigate the anxiety and depression of hospital staff. RESULTS Among 267 hospital staff, anxiety was found in 98 individuals, with a prevalence of 36.70%. Depression was found in 170 individuals, with a prevalence of 63.67%. Anxiety combined with depression was found in 84 individuals, with a prevalence of 31.46%. The prevalence of depression was higher in women, Tibetan personnel, hospital staff with primary or lower titles, staff without career establishment, and non-aid Tibetan personnel, and the differences were all statistically significant (P.","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"29 ","pages":"e939514"},"PeriodicalIF":2.8,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/02/2c/medscimonitbasicres-29-e939514.PMC10204610.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9556324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Questionnaire-Based Study to Compare the Psychological Effects of 6 Weeks of Exercise in 123 Chinese College Students. 123名中国大学生6周运动心理效果的问卷研究

IF 2.8

Medical Science Monitor Basic Research Pub Date : 2023-03-22 DOI: 10.12659/MSMBR.939096

Mei Xue Wei, Zhen Liu

引用次数: 0

Study of 60 Adult Patients to Compare Standard Postoperative Clinical Assessment with Train-of-Four Ratio ≥0.9 on Patient Outcomes Using Postoperative Spirometry and Neuromuscular Function Measurements Following Extubation. 60例成人患者拔管后肺量测定和神经肌肉功能测量比较标准术后临床评估与四训练比值≥0.9患者预后的研究。

IF 2.8

Medical Science Monitor Basic Research Pub Date : 2023-03-08 DOI: 10.12659/MSMBR.938849

Chunlong Chen, Qingzhen Liu, Hong Fan, Zhiyang Yu, Xueyan Leng, Lidong Zhang, Zhiqiang Zhou

{"title":"Study of 60 Adult Patients to Compare Standard Postoperative Clinical Assessment with Train-of-Four Ratio ≥0.9 on Patient Outcomes Using Postoperative Spirometry and Neuromuscular Function Measurements Following Extubation.","authors":"Chunlong Chen, Qingzhen Liu, Hong Fan, Zhiyang Yu, Xueyan Leng, Lidong Zhang, Zhiqiang Zhou","doi":"10.12659/MSMBR.938849","DOIUrl":"https://doi.org/10.12659/MSMBR.938849","url":null,"abstract":"BACKGROUND Postoperative tracheal extubation requires optimal timing to ensure patient safety and normal muscle function. The train-of-four ratio (TOFR) of the fourth muscle response compared with the first indicates a non-depolarizing neuromuscular block, and a ratio ≥0.9 can be used as an objective measurement of neuromuscular reversal. This study of 60 adult patients who underwent elective surgery with general anesthesia that included the neuromuscular blocking agent cisatracurium aimed to compare standard postoperative clinical assessment with the TOFR ≥0.9 on patient outcomes using postoperative neuromuscular function assessed by grip strength and ability to sit up unaided and spirometry measurements following extubation. MATERIAL AND METHODS The 30 patients extubated postoperatively in the TOF group were required to have a TOFR ≥0.9, while the 30 patients in the clinical assessment group were awake and following simple commands and had a 5-second head lift and spontaneous breathing with acceptable oxygenation. The main outcomes were the incentive spirometry and grip strength and ability to sit up unaided measured at 10, 30, 50 min and 24 h after extubation. RESULTS The groups had no difference in recovery path of incentive spirometry volume (P=0.072) and no difference in postoperative incentive spirometry decrease from baseline except at 10 min after extubation (P=0.005). There was no difference in handgrip strength and independent sitting between groups. CONCLUSIONS The findings showed that using the TOF ratio ≥0.9 before extubation did not improve early postoperative strength quantified by spirometry volume, handgrip strength, and proportion of unaided sitting.","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"29 ","pages":"e938849"},"PeriodicalIF":2.8,"publicationDate":"2023-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/86/f7/medscimonitbasicres-29-e938849.PMC10010054.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9118093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Prospective Study of 73 Patients to Compare Forward Head Angle, Forward Shoulder Angle, Maximal Inspiratory Pressure, and Self-Reported Breathing-Related Symptoms Before and After Open-Heart Surgery. 一项73例患者的前瞻性研究，比较前头角、前肩角、最大吸气压力和心内直视手术前后自我报告的呼吸相关症状。

IF 2.8

Medical Science Monitor Basic Research Pub Date : 2023-02-07 DOI: 10.12659/MSMBR.938802

Bussakorn Thanasarn, Wittawat Pibul, Chitima Kulchanarat, Dusarkorn Piathip, Kornanong Yuenyongchaiwat

{"title":"A Prospective Study of 73 Patients to Compare Forward Head Angle, Forward Shoulder Angle, Maximal Inspiratory Pressure, and Self-Reported Breathing-Related Symptoms Before and After Open-Heart Surgery.","authors":"Bussakorn Thanasarn, Wittawat Pibul, Chitima Kulchanarat, Dusarkorn Piathip, Kornanong Yuenyongchaiwat","doi":"10.12659/MSMBR.938802","DOIUrl":"https://doi.org/10.12659/MSMBR.938802","url":null,"abstract":"BACKGROUND Patients who undergo open-heart surgery often experience widespread musculoskeletal and pulmonary complications. These can interfere with their functioning, resulting in soft tissue changes, worsening postural changes, and poor respiratory performance. Therefore, the prospective study aimed to compare forward head angle (FHA) and forward shoulder angle (FSA), maximal inspiratory pressure (MIP), and self-reported breathing dysfunction before and after open-heart surgery. MATERIAL AND METHODS In a prospective observational study of 106 patients, men and women scheduled for open-heart surgery were enrolled. Prior to surgery and before discharge from the hospital, all patients were required to assess FHA and FSA using 2-dimensional motion analysis software, MIP using a respiratory pressure meter, and breathing dysfunction using the 25-item Self Evaluation of Breathing Questionnaire (SEBQ). Paired t test was used to compare differences between before and after surgery. To evaluate associations, logistic regression analysis was performed. RESULTS Of the 106 patients recruited, 73 completed the study. FHA (-Δ6.55±4.77, P.","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"29 ","pages":"e938802"},"PeriodicalIF":2.8,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/69/53/medscimonitbasicres-29-e938802.PMC9921079.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10804588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and Associated Factors of Depression Among Frontline Nurses in Wuhan 6 Months After the Outbreak of COVID-19: A Cross-Sectional Study. 新冠肺炎疫情爆发后6个月武汉市一线护士抑郁患病率及相关因素的横断面研究

IF 2.8

Medical Science Monitor Basic Research Pub Date : 2023-01-10 DOI: 10.12659/MSMBR.938633

Huan Liu, Zhiqing Zhou, Yan Liu, Xiubin Tao, Yuxin Zhan, Ming Zhang

{"title":"Prevalence and Associated Factors of Depression Among Frontline Nurses in Wuhan 6 Months After the Outbreak of COVID-19: A Cross-Sectional Study.","authors":"Huan Liu, Zhiqing Zhou, Yan Liu, Xiubin Tao, Yuxin Zhan, Ming Zhang","doi":"10.12659/MSMBR.938633","DOIUrl":"https://doi.org/10.12659/MSMBR.938633","url":null,"abstract":"BACKGROUND Due to the COVID-19 pandemic, frontline nurses have experienced psychological problems. However, the depression of frontline nurses in Wuhan 6 months after the outbreak of COVID-19 has not been studied adequately. The purpose of this study was to investigate the depression of frontline nurses in Wuhan 6 months after the COVID-19 outbreak and to analyze possible risk and protective factors. MATERIAL AND METHODS Data were collected through Wenjuanxing from 612 frontline nurses in Wuhan national COVID-19-designated hospitals between July 27, 2020, and August 12, 2020. The levels of depression, family functioning, and psychological resilience were assessed among frontline nurses in Wuhan with a depression scale, family function scale, and 10-item psychological resilience scale, respectively. The factors associated with depressive symptoms were identified using the chi-square test and binary logistic regression analysis. RESULTS A total of 126 respondents were included in the study. The overall prevalence of depression was 25.2%. The need for mental health services was a potential risk factor for depressive symptoms, while family functioning and psychological resilience were potential protective factors. The COVID-19 pandemic poses a major challenge to the depressive symptoms of frontline nursing in Wuhan, highlighting the need for all frontline nurses in Wuhan to be screened for depression regularly for timely intervention. CONCLUSIONS To mitigate the impact of the pandemic on depression, psychological interventions for frontline nurses need to be implemented to preserve their mental health.","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"29 ","pages":"e938633"},"PeriodicalIF":2.8,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/61/a1/medscimonitbasicres-29-e938633.PMC9840364.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10861023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of Estimated Glomerular Filtration Rate and Urine Albumin-to-Creatinine Ratio Based on KDIGO 2012 Guideline in a Thai Community Hospital: Prevalence of Chronic Kidney Disease and its Risk Factors. 基于KDIGO 2012指南的肾小球滤过率和尿白蛋白与肌酐比值在泰国社区医院的应用:慢性肾病的患病率及其危险因素

IF 2.8

Medical Science Monitor Basic Research Pub Date : 2022-12-08 DOI: 10.12659/MSMBR.938176

Veeravan Lekskulchai

{"title":"Use of Estimated Glomerular Filtration Rate and Urine Albumin-to-Creatinine Ratio Based on KDIGO 2012 Guideline in a Thai Community Hospital: Prevalence of Chronic Kidney Disease and its Risk Factors.","authors":"Veeravan Lekskulchai","doi":"10.12659/MSMBR.938176","DOIUrl":"https://doi.org/10.12659/MSMBR.938176","url":null,"abstract":"BACKGROUND Kidney disease is hard to detect at its early stage; therefore, the Kidney Disease: Improving Global Outcomes (KDIGO) 2012 guideline was developed for improving care and outcomes of patients with kidney disease. This study aimed to determine clinical outcomes from applying this guideline in a community hospital service. MATERIAL AND METHODS The patients' data were extracted from their medical records and analyzed for outcomes of using the estimated glomerular filtration rate (eGFR) and urine albumin-creatinine ratio (UACR) for detecting kidney disease. RESULTS The eGFR was utilized in 36 172 patients aged ≥18 years, and 76.86% of them had normal kidney function. The prevalence of chronic kidney disease (CKD) was 8.20%; most patients (68%) with CKD were in stages 3a and 3b. The most common causes of CKD were diabetes and hypertension. The UACR was mainly used in patients with diabetes. The percentage of patients with UACR ≥3 mg/mmol creatinine alone was significantly higher than that of patients with eGFR.","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"28 ","pages":"e938176"},"PeriodicalIF":2.8,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f3/f0/medscimonitbasicres-28-e938176.PMC9745955.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10424014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FLT3 Gene Mutations in Acute Myeloid Leukemia Patients in Northeast Thailand. 泰国东北部急性髓性白血病患者FLT3基因突变

IF 2.8

Medical Science Monitor Basic Research Pub Date : 2022-11-24 DOI: 10.12659/MSMBR.937446

Nang Ei Ei Aung, Supawadee Yamsri, Nattiya Teawtrakul, Piyawan Kamsaen, Supan Fucharoen

{"title":"FLT3 Gene Mutations in Acute Myeloid Leukemia Patients in Northeast Thailand.","authors":"Nang Ei Ei Aung, Supawadee Yamsri, Nattiya Teawtrakul, Piyawan Kamsaen, Supan Fucharoen","doi":"10.12659/MSMBR.937446","DOIUrl":"https://doi.org/10.12659/MSMBR.937446","url":null,"abstract":"BACKGROUND Mutations in the FLT3 gene are associated with acute myeloid leukemia (AML). FLT3 mutations have been identified in approximately 30% of de novo AML patients, particularly those with typical karyotype and inferior prognosis. Therefore, we examined the frequencies of an internal tandem duplication (ITD) and missense mutations of the FLT3 gene and their associated clinical characteristics in patients with AML in northeast Thailand. MATERIAL AND METHODS The leftover bone marrow and/or peripheral blood specimens of 65 newly diagnosed AML patients recruited from Srinagarind Hospital, Khon Kaen University, northeast Thailand, between January 2020 and May 2021 were included in this study. FLT3-ITD and FLT3- tyrosine kinase domain (TKD) were amplified using PCR-related techniques. RESULTS The frequencies of FLT3-ITD and TKD were found to be 16.9% (11/65) and 10.8% (7/65), respectively. One patient had ITD and TKD mutations. The white blood cell count and peripheral blast percentage of FLT3-ITD-positive patients were statistically significantly higher than those of the FLT3-wild type patients, while the peripheral blast percentage of FLT3-TKD-positive patients was significantly lower. No other clinical characteristics among FLT3-positive and FLT3-wild-type patients were observed. DNA sequencing identified 4 FLT3-TKD mutations. The c.2504A>T; Asp835Val and c.2503G>C; Asp835His mutations were predicted as pathogenic mutations while the 2 novel mutations, c.2508C>A; Ile836= and c.2508C>G; Ile836Met were predicted as neutral mutations. CONCLUSIONS This study showed for the first time that FLT3-TKD mutation is common among northeast Thai AML patients. The data should prove useful for selecting efficacious targeted treatment plans for the patients.","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"28 ","pages":"e937446"},"PeriodicalIF":2.8,"publicationDate":"2022-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9e/5d/medscimonitbasicres-28-e937446.PMC9707044.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10424013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Calcitriol Inhibits Proliferation and Potentially Induces Apoptosis in B16–F10 Cells 骨化三醇抑制B16-F10细胞增殖并可能诱导凋亡

IF 2.8

Medical Science Monitor Basic Research Pub Date : 2022-05-05 DOI: 10.12659/MSMBR.935139

Eva Krishna Sutedja, Daniar Amarassaphira, H. Goenawan, Y. Pratiwi, N. Sylviana, B. Setiabudiawan, O. Suwarsa, R. Judistiani, U. Supratman, R. Lesmana

{"title":"Calcitriol Inhibits Proliferation and Potentially Induces Apoptosis in B16–F10 Cells","authors":"Eva Krishna Sutedja, Daniar Amarassaphira, H. Goenawan, Y. Pratiwi, N. Sylviana, B. Setiabudiawan, O. Suwarsa, R. Judistiani, U. Supratman, R. Lesmana","doi":"10.12659/MSMBR.935139","DOIUrl":"https://doi.org/10.12659/MSMBR.935139","url":null,"abstract":"Background Melanoma is one of the most aggressive types of cancer and it has shown a remarkable surge in incidence during the last 50 years. Melanoma has been projected to be continuously rising in the future. Therapy for advanced-type melanoma is still a challenge due to the low response rate and poor 10-year survival. Interestingly, several epidemiological and preclinical studies had reported that vitamin D deficiency was associated with disease progression in several cancer types. In vivo and in vitro studies revealed anti-proliferative, anti-angiogenic, apoptosis, and differentiation induction effects of calcitriol in various cancers. However, information on the effects of calcitriol (1,25(OH)2D3) on melanoma is still limited, and its mechanism remains unclear. Material/Methods In the present study, by utilizing B16–F10 cells, which is a melanoma cell line, we explored the anti-proliferative effect of calcitriol using cell viability assay, near-infrared imaging, expression of apoptosis-related genes using real-time polymerase chain reactions (PCR), and the expression of apoptosis proteins levels using western blot. In addition, we also assessed calcitriol uptake by B16–F10 cells using high-performance liquid chromatography (HPLC). Results We found that calcitriol inhibits melanoma cell proliferation with an IC50 of 93.88 ppm (0.24 μM), as shown by cell viability assay. Additionally, we showed that B16–F10 cells are capable of calcitriol uptake, with a peak uptake time at 60 min after administration. Calcitriol was also able to induce apoptosis-related proteins such as caspase-3, caspase 8, and caspase-9. These effects of calcitriol reflect its potential utility as a potent adjuvant therapy for melanoma. Conclusions Calcitriol inhibits cell proliferation and induces apoptosis in B16–F10 cells.","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"82 1","pages":"e935139-1 - e935139-12"},"PeriodicalIF":2.8,"publicationDate":"2022-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83991964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Case-Control Study to Evaluate the Oral Hygiene Habits in 31 Children with Hemophilia in Bulgaria Using the Oral Health Impact Profile-14 (OHIP-14) Questionnaire 使用口腔健康影响概况-14 (OHIP-14)问卷评估保加利亚31例血友病儿童口腔卫生习惯的病例-对照研究

IF 2.8

Medical Science Monitor Basic Research Pub Date : 2022-04-21 DOI: 10.12659/MSMBR.936560

V. Mandova, R. Stefanov

{"title":"Case-Control Study to Evaluate the Oral Hygiene Habits in 31 Children with Hemophilia in Bulgaria Using the Oral Health Impact Profile-14 (OHIP-14) Questionnaire","authors":"V. Mandova, R. Stefanov","doi":"10.12659/MSMBR.936560","DOIUrl":"https://doi.org/10.12659/MSMBR.936560","url":null,"abstract":"Background For patients with hereditary coagulopathies such as hemophilia, the most common dental problem is spontaneous oral bleeding caused by daily oral hygiene habits like tooth brushing. Because of fear of bleeding, children with hemophilia often skip routine oral hygiene procedures, which can lead to dental caries and periodontal diseases. This case control study aimed to evaluate the oral hygiene awareness and hygiene practices of children with hemophilia from 6 to 18 years of age in Bulgaria. Material/Methods This study was conducted over 4 years and included 31 patients (children). A sociological approach was used, with direct individual questionnaires for self-assessment of dental habits. Statistical analyses were performed using SPSS. Results There was no significant difference between groups in methods of oral hygiene. The duration of oral hygiene procedures was 1 min (n=5, 16.13±6.61%) or 2 min (n=13, 41.94±8.86%), which was considered insufficient for proper oral hygiene. Children who had received oral hygiene advice by a dentist brushed their teeth significantly longer (n=9, 69.23±12.80%) than those who had not. There was a considerable difference between the reasons for the last dental visit between the groups of children (χ2=5.18, P<0.05). Conclusions Children with hemophilia have high awareness of oral hygiene methods; however, more attention should be focused on additional individual educational methods at the dental office. Frequent professional and self-assessment of the oral hygiene routine of children with hemophilia could identify the factors compromising dental status in this vulnerable population.","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"15 1","pages":"e936560-1 - e936560-8"},"PeriodicalIF":2.8,"publicationDate":"2022-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83068260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Case-Control Study to Evaluate the Oral Hygiene Habits in 31 Children with Hemophilia in Bulgaria Using the Oral Health Impact Profile-14 (OHIP-14) Questionnaire. 使用口腔健康影响档案-14 (OHIP-14) 问卷评估保加利亚 31 名血友病患儿口腔卫生习惯的病例对照研究。

IF 1.5

Medical Science Monitor Basic Research Pub Date : 2022-04-21

Viktoriya D Mandova, Rumen S Stefanov

{"title":"Case-Control Study to Evaluate the Oral Hygiene Habits in 31 Children with Hemophilia in Bulgaria Using the Oral Health Impact Profile-14 (OHIP-14) Questionnaire.","authors":"Viktoriya D Mandova, Rumen S Stefanov","doi":"","DOIUrl":"","url":null,"abstract":"BACKGROUND For patients with hereditary coagulopathies such as hemophilia, the most common dental problem is spontaneous oral bleeding caused by daily oral hygiene habits like tooth brushing. Because of fear of bleeding, children with hemophilia often skip routine oral hygiene procedures, which can lead to dental caries and periodontal diseases. This case control study aimed to evaluate the oral hygiene awareness and hygiene practices of children with hemophilia from 6 to 18 years of age in Bulgaria. MATERIAL AND METHODS This study was conducted over 4 years and included 31 patients (children). A sociological approach was used, with direct individual questionnaires for self-assessment of dental habits. Statistical analyses were performed using SPSS. RESULTS There was no significant difference between groups in methods of oral hygiene. The duration of oral hygiene procedures was 1 min (n=5, 16.13±6.61%) or 2 min (n=13, 41.94±8.86%), which was considered insufficient for proper oral hygiene. Children who had received oral hygiene advice by a dentist brushed their teeth significantly longer (n=9, 69.23±12.80%) than those who had not. There was a considerable difference between the reasons for the last dental visit between the groups of children (χ²=5.18, P.","PeriodicalId":18491,"journal":{"name":"Medical Science Monitor Basic Research","volume":"28 ","pages":"e936560"},"PeriodicalIF":1.5,"publicationDate":"2022-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141862063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0